{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Stable3"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Stable3","index":0,"n_rows":865,"n_cols":14,"rows_kept":865,"flags":["formulas_cached_only"]}
[null,"DEG in EHF vs HF"]
[null,"GeneID","Length","EHF-Expression","HF-Expression","log2FoldChange(EHF/HF)","Up/Down-Regulation","Pvalue","Symbol","Cellular Component","Molecular Function","Biological Process","Kegg Orthology","Nr Description"]
[null,24153,4614,817.259589848627,15668.3952042698,-4.26091921186762,"DOWN",{"v":8.30137951155923e-21,"d":"8.30E-21"},"A2m","GO:0044421//extracellular region part","GO:0019958//C-X-C chemokine binding;GO:0019838//growth factor binding;GO:0004866//endopeptidase inhibitor activity","GO:0031960//response to corticosteroid;GO:0010466//negative regulation of peptidase activity;GO:0001867//complement activation, lectin pathway;GO:0031667//response to nutrient levels;GO:0010035//response to inorganic substance;GO:0002526//acute inflammatory response","K03910//alpha-2-macroglobulin","gi|158138551|ref|NP_036620.2|//alpha-2-macroglobulin precursor [Rattus norvegicus]"]
[null,24171,3015,4.43623978832862,19.2472803107568,-2.11724535026321,"DOWN",0.00196605353672928,"Add2","GO:0016020//membrane;GO:0015629//actin cytoskeleton","GO:0003779//actin binding;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0046983//protein dimerization activity","GO:0006810//transport;GO:0051693//actin filament capping;GO:0043393//regulation of protein binding;GO:0048534//hematopoietic or lymphoid organ development","K18622//adducin","gi|158081763|ref|NP_001103350.1|//beta-adducin isoform a [Rattus norvegicus];gi|6978449|ref|NP_036623.1|//beta-adducin isoform b [Rattus norvegicus]"]
[null,24188,2119,5346.86636627177,2666.73008768289,1.0036218097302,"UP",0.0107965895778975,"Aldh1a1","GO:0005829//cytosol;GO:0044444//cytoplasmic part;GO:0048471//perinuclear region of cytoplasm","GO:0019115//benzaldehyde dehydrogenase activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0005515//protein binding;GO:0001758//retinal dehydrogenase activity;GO:0018479//benzaldehyde dehydrogenase (NAD+) activity;GO:0016918//retinal binding;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity","GO:0060324//face development;GO:0048738//cardiac muscle tissue development;GO:0051260//protein homooligomerization;GO:0001568//blood vessel development;GO:0043627//response to estrogen;GO:0042573//retinoic acid metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0021915//neural tube development;GO:0033189//response to vitamin A;GO:0008285//negative regulation of cell proliferation;GO:0022602//ovulation cycle process;GO:0035799//ureter maturation;GO:0048562//embryonic organ morphogenesis;GO:0031076//embryonic camera-type eye development;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0071300//cellular response to retinoic acid;GO:0030900//forebrain development;GO:0016331//morphogenesis of embryonic epithelium;GO:0001936//regulation of endothelial cell proliferation;GO:0009954//proximal/distal pattern formation;GO:0048566//embryonic digestive tract development;GO:0030902//hindbrain development;GO:0030324//lung development;GO:0009952//anterior/posterior pattern specification;GO:0006950//response to stress;GO:0042574//retinal metabolic process;GO:0034097//response to cytokine;GO:0055114//oxidation-reduction process;GO:0014032//neural crest cell development;GO:0030182//neuron differentiation;GO:0002138//retinoic acid biosynthetic process;GO:0048384//retinoic acid receptor signaling pathway;GO:0007612//learning;GO:0048565//digestive tract development;GO:0035115//embryonic forelimb morphogenesis;GO:0001947//heart looping;GO:0031016//pancreas development;GO:0035238//vitamin A biosynthetic process;GO:0008284//positive regulation of cell proliferation","K07249//retinal dehydrogenase [EC:1.2.1.36]","gi|589945586|ref|XP_006985474.1|//PREDICTED: retinal dehydrogenase 1 [Peromyscus maniculatus bairdii];gi|28386049|gb|AAH44729.1|//Aldh1a1 protein, partial [Mus musculus]"]
[null,24192,1339,71.9498579922607,152.499035653465,-1.08373637501593,"DOWN",0.00131095424578677,"Akr1b1","GO:0031981//nuclear lumen;GO:0044421//extracellular region part;GO:0044444//cytoplasmic part","GO:0004033//aldo-keto reductase (NADP) activity","GO:0042221//response to chemical;GO:0008284//positive regulation of cell proliferation;GO:0006060//sorbitol metabolic process;GO:0006629//lipid metabolic process","K00011//aldehyde reductase [EC:1.1.1.21]","gi|6978491|ref|NP_036630.1|//aldose reductase [Rattus norvegicus]"]
[null,24251,1710,94.9801968379336,210.36275052405,-1.14718061433745,"DOWN",0.0115558413848332,"Cd53","GO:0031224//intrinsic component of membrane","NA","GO:0050789//regulation of biological process;GO:0023052//signaling","K06489//CD53 antigen","gi|6978633|ref|NP_036655.1|//leukocyte surface antigen CD53 [Rattus norvegicus]"]
[null,24297,1882,8648.05197503916,17686.839531793,-1.03222917647313,"DOWN",0.0164368384463216,"Cyp1a2","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0033695//oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0018894//dibenzo-p-dioxin metabolic process;GO:0009404//toxin metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0030323//respiratory tube development;GO:0017144//drug metabolic process;GO:0043627//response to estrogen;GO:0008202//steroid metabolic process;GO:0009698//phenylpropanoid metabolic process;GO:0042493//response to drug;GO:0042743//hydrogen peroxide metabolic process;GO:0006730//one-carbon metabolic process;GO:0006805//xenobiotic metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0019752//carboxylic acid metabolic process;GO:0033013//tetrapyrrole metabolic process;GO:0010467//gene expression;GO:0006721//terpenoid metabolic process;GO:0035238//vitamin A biosynthetic process","K07409//cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]","gi|158186713|ref|NP_036673.3|//cytochrome P450 1A2 [Rattus norvegicus]"]
[null,24299,1696,10.9359298717928,64.3520217292062,-2.55690957729976,"DOWN",{"v":6.40084170453023e-05,"d":"6.40E-05"},"Cyp2a3","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0042493//response to drug;GO:0009804//coumarin metabolic process;GO:0006629//lipid metabolic process","K07411//cytochrome P450 family 2 subfamily A [EC:1.14.14.1];K17685//cytochrome P450 family 2 subfamily A polypeptide 13 [EC:1.14.14.1]","gi|6978743|ref|NP_036674.1|//cytochrome P450 2A3 [Rattus norvegicus]"]
[null,24309,1610,156.057538812,754.474076815802,-2.27339327913571,"DOWN",{"v":5.31978119597834e-06,"d":"5.32E-06"},"Dbp","GO:0043231//intracellular membrane-bounded organelle","GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0048511//rhythmic process","K09056//albumin D box-binding protein","gi|586597897|ref|NP_001276911.1|//D site-binding protein isoform 2 [Rattus norvegicus];gi|586597916|ref|NP_001276912.1|//D site-binding protein isoform 3 [Rattus norvegicus];gi|7549756|ref|NP_036675.1|//D site-binding protein isoform 1 [Rattus norvegicus]"]
[null,24310,4142,19.539319234989,80.669978217616,-2.04565166280805,"DOWN",0.000210654893639123,"Ace","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part;GO:0009986//cell surface","GO:0043168//anion binding;GO:0008238//exopeptidase activity;GO:0001664//G-protein coupled receptor binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding","GO:0015909//long-chain fatty acid transport;GO:0009991//response to extracellular stimulus;GO:0007600//sensory perception;GO:0048513//animal organ development;GO:0031349//positive regulation of defense response;GO:0006518//peptide metabolic process;GO:0050880//regulation of blood vessel size;GO:0014909//smooth muscle cell migration;GO:0002237//response to molecule of bacterial origin;GO:0006915//apoptotic process;GO:0019538//protein metabolic process;GO:0007631//feeding behavior;GO:0010720//positive regulation of cell development;GO:0009056//catabolic process;GO:0002444//myeloid leukocyte mediated immunity","K01283//peptidyl-dipeptidase A [EC:3.4.15.1]","gi|6978757|ref|NP_036676.1|//angiotensin-converting enzyme precursor [Rattus norvegicus]"]
[null,24314,1480,357.310642924717,996.126533364757,-1.47915012587877,"DOWN",{"v":4.83092796546319e-05,"d":"4.83E-05"},"Nqo1","GO:0044424//intracellular part","GO:0048037//cofactor binding;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor","GO:0043065//positive regulation of apoptotic process;GO:0044092//negative regulation of molecular function;GO:0008152//metabolic process;GO:0006950//response to stress","K00355//NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]","gi|27501444|ref|NP_058696.2|//NAD(P)H dehydrogenase [quinone] 1 [Rattus norvegicus]"]
[null,24326,4595,23.8642744258824,73.5445092660844,-1.62376516276211,"DOWN",0.0015028356882143,"Ednra","GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0042383//sarcolemma","GO:0004672//protein kinase activity;GO:0004962//endothelin receptor activity;GO:0004629//phospholipase C activity","GO:0007600//sensory perception;GO:0001822//kidney development;GO:0014031//mesenchymal cell development;GO:0042127//regulation of cell proliferation;GO:0050880//regulation of blood vessel size;GO:0002237//response to molecule of bacterial origin;GO:0043009//chordate embryonic development;GO:0003014//renal system process;GO:0001932//regulation of protein phosphorylation;GO:0042476//odontogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0001525//angiogenesis;GO:0031349//positive regulation of defense response;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0008645//hexose transport;GO:0006915//apoptotic process;GO:0010863//positive regulation of phospholipase C activity;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007620//copulation;GO:0014072//response to isoquinoline alkaloid;GO:0014820//tonic smooth muscle contraction;GO:0043410//positive regulation of MAPK cascade;GO:0033002//muscle cell proliferation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0048609//multicellular organismal reproductive process;GO:0007265//Ras protein signal transduction;GO:0046903//secretion","K04197//endothelin receptor type A","gi|7549758|ref|NP_036682.1|//endothelin-1 receptor precursor [Rattus norvegicus]"]
[null,24346,1872,10240.7783207021,4583.94110815745,1.15966495295458,"UP",0.0142242686944151,"Ces1c","GO:0005788//endoplasmic reticulum lumen;GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0044432//endoplasmic reticulum part","GO:0052689//carboxylic ester hydrolase activity","GO:0030855//epithelial cell differentiation","K01044//carboxylesterase 1 [EC:3.1.1.1]","gi|57529187|ref|NP_058700.1|//carboxylesterase 1C precursor [Rattus norvegicus];gi|564394681|ref|XP_006255234.1|//PREDICTED: carboxylesterase 1C isoform X1 [Rattus norvegicus]"]
[null,24360,551,23738.725827185,10100.3066955786,1.23284339955815,"UP",0.00143767591962811,"Fabp1","GO:0070062//extracellular exosome;GO:0045179//apical cortex;GO:0005654//nucleoplasm;GO:0044439//peroxisomal part;GO:0043234//protein complex;GO:0005829//cytosol;GO:0044448//cell cortex part;GO:0005782//peroxisomal matrix","GO:0032052//bile acid binding;GO:0051978//lysophospholipid transporter activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005543//phospholipid binding;GO:0015245//fatty acid transporter activity;GO:0016209//antioxidant activity;GO:0005515//protein binding;GO:0008144//drug binding;GO:0003682//chromatin binding;GO:0005504//fatty acid binding;GO:0005496//steroid binding;GO:0005548//phospholipid transporter activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071456//cellular response to hypoxia;GO:0000087//mitotic M phase;GO:0050892//intestinal absorption;GO:0007067//mitotic nuclear division;GO:0006635//fatty acid beta-oxidation;GO:0008283//cell proliferation;GO:0015914//phospholipid transport;GO:0051977//lysophospholipid transport;GO:0043085//positive regulation of catalytic activity;GO:0070301//cellular response to hydrogen peroxide;GO:0015909//long-chain fatty acid transport;GO:0098779//mitophagy in response to mitochondrial depolarization;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0015908//fatty acid transport;GO:0051345//positive regulation of hydrolase activity;GO:0022600//digestive system process;GO:0098792//xenophagy;GO:0098869//cellular oxidant detoxification;GO:0002230//positive regulation of defense response to virus by host;GO:0008284//positive regulation of cell proliferation","K08750//fatty acid-binding protein 1, liver","gi|6978825|ref|NP_036688.1|//fatty acid-binding protein, liver [Rattus norvegicus]"]
[null,24366,1596,88184.8864462578,182002.543711434,-1.04535528801419,"DOWN",0.0262697691195215,"Fgb","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005577//fibrinogen complex;GO:0072562//blood microparticle;GO:0005938//cell cortex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0031091//platelet alpha granule","GO:0050839//cell adhesion molecule binding;GO:0005515//protein binding;GO:0030674//protein binding, bridging;GO:0005102//receptor binding;GO:0005198//structural molecule activity;GO:0051087//chaperone binding","GO:0045921//positive regulation of exocytosis;GO:0045907//positive regulation of vasoconstriction;GO:0071347//cellular response to interleukin-1;GO:0023052//signaling;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043152//induction of bacterial agglutination;GO:0044320//cellular response to leptin stimulus;GO:0072378//blood coagulation, fibrin clot formation;GO:0007599//hemostasis;GO:0010038//response to metal ion;GO:0045087//innate immune response;GO:0090277//positive regulation of peptide hormone secretion;GO:0009611//response to wounding;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0031639//plasminogen activation;GO:0002250//adaptive immune response;GO:0007160//cell-matrix adhesion;GO:0050714//positive regulation of protein secretion;GO:0051258//protein polymerization;GO:0001775//cell activation;GO:0051592//response to calcium ion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0043623//cellular protein complex assembly;GO:0006887//exocytosis","K03904//fibrinogen beta chain","gi|564336898|ref|XP_006232586.1|//PREDICTED: fibrinogen beta chain isoform X2 [Rattus norvegicus];gi|344239875|gb|EGV95978.1|//Fibrinogen beta chain [Cricetulus griseus];gi|158186678|ref|NP_064456.2|//fibrinogen beta chain precursor [Rattus norvegicus]"]
[null,24367,1576,61123.8241492428,155462.610539529,-1.3467609353533,"DOWN",0.000544300526154059,"Fgg","GO:0016020//membrane;GO:0030141//secretory granule;GO:0009986//cell surface;GO:0005615//extracellular space","GO:0005515//protein binding","GO:0001775//cell activation;GO:0006952//defense response;GO:0023052//signaling;GO:0010038//response to metal ion;GO:0043623//cellular protein complex assembly","K03903//fibrinogen alpha chain;K03905//fibrinogen gamma chain","gi|531999343|ref|XP_005344206.1|//PREDICTED: fibrinogen gamma chain isoform X2 [Microtus ochrogaster];gi|61098186|ref|NP_036691.2|//fibrinogen gamma chain precursor [Rattus norvegicus];gi|944215099|gb|KQK81492.1|//hypothetical protein AAES_83371 [Amazona aestiva]"]
[null,24373,2202,48.0011649336969,131.542616531296,-1.45438894856547,"DOWN",0.0268718843377866,"Fst","GO:0043231//intracellular membrane-bounded organelle","GO:0060089//molecular transducer activity;GO:0043394//proteoglycan binding;GO:0032403//protein complex binding","GO:0045684//positive regulation of epidermis development;GO:0032924//activin receptor signaling pathway;GO:0032277//negative regulation of gonadotropin secretion;GO:0019953//sexual reproduction;GO:0008406//gonad development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0030097//hemopoiesis;GO:0001942//hair follicle development;GO:0045595//regulation of cell differentiation;GO:0042476//odontogenesis","K04661//follistatin","gi|6978857|ref|NP_036693.1|//follistatin precursor [Rattus norvegicus]"]
[null,24422,912,5082.09069301218,1785.11312208202,1.50940662109273,"UP",0.00109193154760348,"Gsta2","GO:0070062//extracellular exosome;GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0044444//cytoplasmic part;GO:0005640//nuclear outer membrane","GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0008144//drug binding;GO:0042277//peptide binding","GO:0032502//developmental process;GO:0042178//xenobiotic catabolic process;GO:0035634//response to stilbenoid;GO:0006805//xenobiotic metabolic process;GO:0007568//aging","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|58331251|ref|NP_001010921.1|//glutathione S-transferase alpha-2 [Rattus norvegicus];gi|51036637|ref|NP_058709.2|//glutathione S-transferase alpha-1 [Rattus norvegicus]"]
[null,24423,1063,17384.701460382,8537.68535448081,1.02590139253887,"UP",0.0290065796121393,"Gstm1","GO:0044424//intracellular part;GO:0043234//protein complex;GO:0005576//extracellular region;GO:0043209//myelin sheath;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0008289//lipid binding;GO:0043295//glutathione binding;GO:0016151//nickel cation binding;GO:0005496//steroid binding","GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0001101//response to acid chemical;GO:0035690//cellular response to drug;GO:0010226//response to lithium ion;GO:0070458//cellular detoxification of nitrogen compound;GO:0045471//response to ethanol;GO:0046677//response to antibiotic;GO:0010038//response to metal ion;GO:0042178//xenobiotic catabolic process;GO:0007608//sensory perception of smell;GO:0048678//response to axon injury;GO:0007606//sensory perception of chemical stimulus;GO:0006749//glutathione metabolic process;GO:0010288//response to lead ion;GO:0018916//nitrobenzene metabolic process","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|8393502|ref|NP_058710.1|//glutathione S-transferase Mu 1 [Rattus norvegicus];gi|149025664|gb|EDL81907.1|//rCG29047, isoform CRA_b [Rattus norvegicus]"]
[null,24446,2532,51.5644516645292,178.141535930863,-1.78857521308325,"DOWN",0.000449584133728607,"Hgf","GO:0044421//extracellular region part","GO:0004175//endopeptidase activity;GO:0070851//growth factor receptor binding;GO:0046983//protein dimerization activity","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009887//animal organ morphogenesis;GO:0032989//cellular component morphogenesis;GO:0000165//MAPK cascade;GO:0008283//cell proliferation;GO:0019538//protein metabolic process;GO:0060638//mesenchymal-epithelial cell signaling;GO:0043066//negative regulation of apoptotic process","K05460//hepatocyte growth factor","gi|433431|emb|CAA51054.1|//hepatocyte growth factor [Mus musculus]"]
[null,24472,4045,3685.84185582558,901.003439306663,2.03238965402922,"UP",0.000325069300523134,"Hspa1a","GO:0032991//macromolecular complex;GO:0044429//mitochondrial part;GO:0044459//plasma membrane part;GO:0016604//nuclear body","GO:0032559//adenyl ribonucleotide binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0006401//RNA catabolic process;GO:0006457//protein folding;GO:0010466//negative regulation of peptidase activity;GO:0019229//regulation of vasoconstriction;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0016049//cell growth;GO:0006259//DNA metabolic process;GO:0008283//cell proliferation;GO:0033028//myeloid cell apoptotic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity","K03283//heat shock 70kDa protein 1/8","gi|47059179|ref|NP_997669.1|//heat shock 70kD protein 1B [Rattus norvegicus]"]
[null,24536,4600,311.256114538383,653.547997961423,-1.07019101572276,"DOWN",0.0235240106827304,"Lepr","GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex","GO:0005515//protein binding;GO:0016500//protein-hormone receptor activity;GO:0038021//leptin receptor activity;GO:0017046//peptide hormone binding;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity","GO:1904060//negative regulation of locomotor rhythm;GO:0014070//response to organic cyclic compound;GO:0008203//cholesterol metabolic process;GO:0006950//response to stress;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045721//negative regulation of gluconeogenesis;GO:0019953//sexual reproduction;GO:1903999//negative regulation of eating behavior;GO:0098868//bone growth;GO:0043086//negative regulation of catalytic activity;GO:0033210//leptin-mediated signaling pathway;GO:0044237//cellular metabolic process;GO:0016125//sterol metabolic process;GO:0046850//regulation of bone remodeling;GO:0051346//negative regulation of hydrolase activity;GO:0006909//phagocytosis;GO:0022602//ovulation cycle process;GO:0001525//angiogenesis;GO:0048545//response to steroid hormone;GO:0007631//feeding behavior;GO:0031667//response to nutrient levels;GO:0010507//negative regulation of autophagy;GO:0043410//positive regulation of MAPK cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030217//T cell differentiation;GO:2000505//regulation of energy homeostasis","K05062//leptin receptor","gi|1381733|gb|AAC52706.1|//leptin receptor short form [Mus musculus];gi|148698917|gb|EDL30864.1|//leptin receptor, isoform CRA_b, partial [Mus musculus];gi|6981150|ref|NP_036728.1|//leptin receptor precursor [Rattus norvegicus]"]
[null,24539,3055,50.4241238879233,173.362656179967,-1.78160714545442,"DOWN",0.000188384492727794,"Lpl","GO:0031224//intrinsic component of membrane;GO:0034385//triglyceride-rich lipoprotein particle","GO:0008289//lipid binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding","GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0010878//cholesterol storage;GO:0010742//macrophage derived foam cell differentiation;GO:0042221//response to chemical;GO:0006641//triglyceride metabolic process;GO:0006631//fatty acid metabolic process;GO:0055088//lipid homeostasis;GO:0010884//positive regulation of lipid storage","K01059//lipoprotein lipase [EC:3.1.1.34]","gi|6981168|ref|NP_036730.1|//lipoprotein lipase precursor [Rattus norvegicus]"]
[null,24582,6555,55.7061216362087,128.976693439074,-1.21120260743059,"DOWN",0.0252310039310922,"Myh11","GO:0032432//actin filament bundle;GO:0016460//myosin II complex;GO:0043292//contractile fiber","GO:0032559//adenyl ribonucleotide binding;GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity","GO:0006936//muscle contraction;GO:0048747//muscle fiber development;GO:0085029//extracellular matrix assembly","K10352//myosin heavy chain","gi|282158051|ref|NP_001164071.1|//myosin-11 [Rattus norvegicus]"]
[null,24599,3793,14.0543923873111,36.7850173938627,-1.38809719041908,"DOWN",0.0146013963553119,"Nos2","GO:0005856//cytoskeleton;GO:0042579//microbody","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0016597//amino acid binding;GO:0019887//protein kinase regulator activity;GO:0005506//iron ion binding;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0050662//coenzyme binding","GO:0032502//developmental process;GO:0048771//tissue remodeling;GO:0016310//phosphorylation;GO:0042742//defense response to bacterium;GO:0032496//response to lipopolysaccharide;GO:0030073//insulin secretion;GO:0043627//response to estrogen;GO:0006525//arginine metabolic process;GO:0034341//response to interferon-gamma;GO:0009611//response to wounding;GO:0050673//epithelial cell proliferation;GO:0022602//ovulation cycle process;GO:0031343//positive regulation of cell killing;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0072593//reactive oxygen species metabolic process;GO:0033280//response to vitamin D;GO:0006915//apoptotic process;GO:0030522//intracellular receptor signaling pathway;GO:0008015//blood circulation;GO:0019222//regulation of metabolic process;GO:0044057//regulation of system process;GO:0017014//protein nitrosylation;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K13241//nitric-oxide synthase, inducible [EC:1.14.13.39]","gi|148298711|ref|NP_036743.3|//nitric oxide synthase, inducible [Rattus norvegicus]"]
[null,24614,768,26779.9439734617,69261.9470317403,-1.37091000150465,"DOWN",0.00219094950246535,"Orm1","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0072562//blood microparticle","GO:0008144//drug binding;GO:0005488//binding","GO:0031100//animal organ regeneration;GO:0071385//cellular response to glucocorticoid stimulus;GO:0032715//negative regulation of interleukin-6 production;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0002237//response to molecule of bacterial origin;GO:0060416//response to growth hormone;GO:0033197//response to vitamin E;GO:0051384//response to glucocorticoid;GO:0006810//transport;GO:0002439//chronic inflammatory response to antigenic stimulus;GO:0042493//response to drug;GO:0006953//acute-phase response;GO:0032526//response to retinoic acid;GO:0002526//acute inflammatory response;GO:0071300//cellular response to retinoic acid;GO:0009887//animal organ morphogenesis;GO:0002682//regulation of immune system process;GO:0071378//cellular response to growth hormone stimulus;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0002437//inflammatory response to antigenic stimulus","K17308//alpha-1-acid glycoprotein 1","gi|16757980|ref|NP_445740.1|//alpha-1-acid glycoprotein precursor [Rattus norvegicus]"]
[null,24617,3053,105.082938618112,590.589615919764,-2.4906275396612,"DOWN",{"v":2.2203442474186e-06,"d":"2.22E-06"},"Serpine1","GO:0016020//membrane;GO:0044421//extracellular region part;GO:0031091//platelet alpha granule","GO:0004175//endopeptidase activity;GO:0004866//endopeptidase inhibitor activity;GO:0019899//enzyme binding","GO:0009888//tissue development;GO:0032496//response to lipopolysaccharide;GO:0014909//smooth muscle cell migration;GO:0042742//defense response to bacterium;GO:0001819//positive regulation of cytokine production;GO:0045807//positive regulation of endocytosis;GO:0009629//response to gravity;GO:0002540//leukotriene production involved in inflammatory response;GO:0008283//cell proliferation;GO:0002548//monocyte chemotaxis;GO:0010466//negative regulation of peptidase activity;GO:0030195//negative regulation of blood coagulation;GO:0016525//negative regulation of angiogenesis;GO:0031349//positive regulation of defense response;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0032102//negative regulation of response to external stimulus;GO:0031960//response to corticosteroid;GO:0006979//response to oxidative stress;GO:0033500//carbohydrate homeostasis;GO:0001775//cell activation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0010755//regulation of plasminogen activation;GO:0009966//regulation of signal transduction;GO:0030194//positive regulation of blood coagulation;GO:0006887//exocytosis","K03982//plasminogen activator inhibitor 1","gi|6981332|ref|NP_036752.1|//plasminogen activator inhibitor 1 precursor [Rattus norvegicus]"]
[null,24653,2855,51.3418997516139,124.007717497553,-1.27222132352667,"DOWN",0.00810561983995399,"Pla2g4a","GO:0030141//secretory granule;GO:0031090//organelle membrane","GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0004623//phospholipase A2 activity","GO:0003006//developmental process involved in reproduction;GO:0048875//chemical homeostasis within a tissue;GO:0002237//response to molecule of bacterial origin;GO:0000302//response to reactive oxygen species;GO:0046677//response to antibiotic;GO:0008283//cell proliferation;GO:0010038//response to metal ion;GO:0001516//prostaglandin biosynthetic process;GO:0015909//long-chain fatty acid transport;GO:0022602//ovulation cycle process;GO:0000038//very long-chain fatty acid metabolic process;GO:0030282//bone mineralization;GO:0031349//positive regulation of defense response;GO:0001660//fever generation;GO:0006915//apoptotic process;GO:0031960//response to corticosteroid;GO:0006906//vesicle fusion;GO:0006644//phospholipid metabolic process;GO:0033273//response to vitamin","K16342//cytosolic phospholipase A2 [EC:3.1.1.4]","gi|126722674|ref|NP_598235.2|//cytosolic phospholipase A2 [Rattus norvegicus]"]
[null,24686,2142,34.94084931206,75.6908261451736,-1.11520377728387,"DOWN",0.0116745309600799,"Prnp","GO:0043231//intracellular membrane-bounded organelle;GO:0031225//anchored component of membrane","GO:0015631//tubulin binding;GO:0046914//transition metal ion binding","GO:0043066//negative regulation of apoptotic process;GO:0010038//response to metal ion","K05634//prion protein","gi|667481282|gb|AIG55232.1|//prion protein, partial [Rattus losea]"]
[null,24718,11344,407.701842101434,956.590811485412,-1.23038745830418,"DOWN",0.00485300494359953,"Reln","GO:0031012//extracellular matrix;GO:0030425//dendrite;GO:0030424//axon;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0043005//neuron projection;GO:0005578//proteinaceous extracellular matrix;GO:0043204//perikaryon;GO:0044424//intracellular part;GO:0005886//plasma membrane","GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0008236//serine-type peptidase activity","GO:0001101//response to acid chemical;GO:0021766//hippocampus development;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0038026//reelin-mediated signaling pathway;GO:0009611//response to wounding;GO:0097120//receptor localization to synapse;GO:0051414//response to cortisol;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:2000969//positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0071549//cellular response to dexamethasone stimulus;GO:0007155//cell adhesion;GO:0033674//positive regulation of kinase activity;GO:0021769//orbitofrontal cortex development;GO:0051412//response to corticosterone;GO:0097119//postsynaptic density protein 95 clustering;GO:0021800//cerebral cortex tangential migration;GO:0043200//response to amino acid;GO:0010226//response to lithium ion;GO:0009636//response to toxic substance;GO:0048265//response to pain;GO:0006935//chemotaxis;GO:0010038//response to metal ion;GO:0000902//cell morphogenesis;GO:0051705//multi-organism behavior;GO:0021536//diencephalon development;GO:0032793//positive regulation of CREB transcription factor activity;GO:0090129//positive regulation of synapse maturation;GO:0042403//thyroid hormone metabolic process;GO:0050795//regulation of behavior;GO:0007494//midgut development;GO:0021854//hypothalamus development;GO:0032570//response to progesterone;GO:0009628//response to abiotic stimulus;GO:0045471//response to ethanol;GO:0021795//cerebral cortex cell migration;GO:0033555//multicellular organismal response to stress;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0007411//axon guidance;GO:0033993//response to lipid;GO:0009612//response to mechanical stimulus;GO:0042493//response to drug;GO:0097114//NMDA glutamate receptor clustering;GO:0035176//social behavior;GO:0021511//spinal cord patterning;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0006575//cellular modified amino acid metabolic process;GO:0006468//protein phosphorylation;GO:0021542//dentate gyrus development;GO:0006508//proteolysis;GO:0070542//response to fatty acid;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0003002//regionalization;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0032008//positive regulation of TOR signaling;GO:0017085//response to insecticide;GO:0007616//long-term memory;GO:0051602//response to electrical stimulus;GO:1902078//positive regulation of lateral motor column neuron migration;GO:0021819//layer formation in cerebral cortex;GO:0031175//neuron projection development;GO:0007611//learning or memory;GO:0010001//glial cell differentiation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:0048678//response to axon injury;GO:0021517//ventral spinal cord development;GO:0048565//digestive tract development;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0009967//positive regulation of signal transduction","K06249//reelin [EC:3.4.21.-]","gi|31543579|ref|NP_536319.2|//reelin precursor [Rattus norvegicus]"]
[null,24778,2571,43.1169112394977,112.110778824663,-1.37859925512522,"DOWN",0.00644636503157113,"Slc2a1","GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0048770//pigment granule;GO:0045120//pronucleus","GO:0051183//vitamin transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005402//cation:sugar symporter activity;GO:0019899//enzyme binding","GO:0051180//vitamin transport;GO:0006766//vitamin metabolic process;GO:0009267//cellular response to starvation;GO:0044238//primary metabolic process;GO:0030073//insulin secretion;GO:0008645//hexose transport;GO:0015980//energy derivation by oxidation of organic compounds","K07299//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1","gi|20301952|ref|NP_620182.1|//solute carrier family 2, facilitated glucose transporter member 1 [Rattus norvegicus]"]
[null,24779,4508,46.4646927512958,157.34195652006,-1.75969665534686,"DOWN",0.00354710477312127,"Slc4a1","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0072562//blood microparticle;GO:0044459//plasma membrane part;GO:0030863//cortical cytoskeleton;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0030018//Z disc;GO:0031674//I band;GO:0016021//integral component of membrane;GO:0014704//intercalated disc","GO:0015108//chloride transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0005452//inorganic anion exchanger activity;GO:0042803//protein homodimerization activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0003779//actin binding;GO:0015301//anion:anion antiporter activity;GO:0008022//protein C-terminus binding;GO:0030506//ankyrin binding;GO:0015103//inorganic anion transmembrane transporter activity;GO:0019899//enzyme binding","GO:0010037//response to carbon dioxide;GO:0014823//response to activity;GO:0042102//positive regulation of T cell proliferation;GO:0051453//regulation of intracellular pH;GO:0042542//response to hydrogen peroxide;GO:0015701//bicarbonate transport;GO:0006821//chloride transport;GO:0046685//response to arsenic-containing substance;GO:0015698//inorganic anion transport;GO:0051259//protein oligomerization","K06573//solute carrier family 4 (anion exchanger), member 1","gi|76443687|ref|NP_036783.2|//band 3 anion transport protein [Rattus norvegicus];gi|20141169|sp|P23562.3|B3AT_RAT//RecName: Full=Band 3 anion transport protein; AltName: Full=Anion exchange protein 1; Short=AE 1; Short=Anion exchanger 1; AltName: Full=Solute carrier family 4 member 1; AltName: CD_antigen=CD233"]
[null,24791,2072,881.372436929302,1900.55905158786,-1.10860016617789,"DOWN",0.00218164033774581,"Sparc","GO:0005615//extracellular space;GO:0016363//nuclear matrix;GO:0005578//proteinaceous extracellular matrix;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005604//basement membrane;GO:0031092//platelet alpha granule membrane","GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding","GO:0010595//positive regulation of endothelial cell migration;GO:0009628//response to abiotic stimulus;GO:0030323//respiratory tube development;GO:0009629//response to gravity;GO:0045471//response to ethanol;GO:0071363//cellular response to growth factor stimulus;GO:0007599//hemostasis;GO:0033591//response to L-ascorbic acid;GO:0009611//response to wounding;GO:0001937//negative regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0007507//heart development;GO:0031960//response to corticosteroid;GO:0046686//response to cadmium ion;GO:0051592//response to calcium ion;GO:0070848//response to growth factor;GO:0033273//response to vitamin;GO:0030324//lung development;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0002237//response to molecule of bacterial origin;GO:0001503//ossification;GO:0008283//cell proliferation;GO:0048839//inner ear development;GO:0023052//signaling;GO:0051384//response to glucocorticoid;GO:0010038//response to metal ion;GO:0060348//bone development;GO:0016525//negative regulation of angiogenesis;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0001775//cell activation;GO:0010288//response to lead ion;GO:0022604//regulation of cell morphogenesis;GO:0006887//exocytosis","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican);K12819//pre-mRNA-processing factor SLU7;K17550//protein phosphatase 1 regulatory subunit 7","gi|6981574|ref|NP_036788.1|//SPARC precursor [Rattus norvegicus]"]
[null,24792,1755,5344.2872235582,2379.61716895035,1.1672680536576,"UP",0.0179124802661055,"Agxt","GO:0005759//mitochondrial matrix;GO:0044429//mitochondrial part;GO:0005782//peroxisomal matrix;GO:0042579//microbody","GO:0008453//alanine-glyoxylate transaminase activity;GO:0016597//amino acid binding;GO:0031406//carboxylic acid binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0004760//serine-pyruvate transaminase activity;GO:0008483//transaminase activity;GO:0048037//cofactor binding;GO:0030170//pyridoxal phosphate binding","GO:0042853//L-alanine catabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0042866//pyruvate biosynthetic process;GO:0019532//oxalate transport;GO:0010498//proteasomal protein catabolic process;GO:0051384//response to glucocorticoid;GO:0006605//protein targeting;GO:0046724//oxalic acid secretion;GO:0006090//pyruvate metabolic process;GO:0051591//response to cAMP;GO:0009436//glyoxylate catabolic process;GO:0031960//response to corticosteroid;GO:0019265//glycine biosynthetic process, by transamination of glyoxylate;GO:0019448//L-cysteine catabolic process;GO:0007219//Notch signaling pathway;GO:0006545//glycine biosynthetic process","K00830//alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]","gi|397529546|ref|NP_085914.2|//serine--pyruvate aminotransferase, mitochondrial isoform 1 precursor [Rattus norvegicus];gi|397529548|ref|NP_001257588.1|//serine--pyruvate aminotransferase isoform 2 [Rattus norvegicus];gi|149037531|gb|EDL91962.1|//alanine-glyoxylate aminotransferase, isoform CRA_c [Rattus norvegicus]"]
[null,24795,5192,57550.152340623,147413.060287591,-1.35697269546562,"DOWN",0.0001136609532428,"Serpina3n","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0044464//cell part","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0006508//proteolysis;GO:0006952//defense response;GO:0009725//response to hormone;GO:0006953//acute-phase response;GO:0043434//response to peptide hormone;GO:0034097//response to cytokine","K04525//serpin peptidase inhibitor, clade A","gi|13928716|ref|NP_113719.1|//serine protease inhibitor A3N [Rattus norvegicus];gi|68053311|sp|Q91WP6.1|SPA3N_MOUSE//RecName: Full=Serine protease inhibitor A3N; Short=Serpin A3N; Flags: Precursor"]
[null,24807,3408,19.8218564350645,49.9312950539201,-1.33285224008147,"DOWN",0.038950886014117,"Tacr1","GO:0031224//intrinsic component of membrane;GO:0044424//intracellular part;GO:0043005//neuron projection","GO:0004995//tachykinin receptor activity","GO:0008217//regulation of blood pressure;GO:0007320//insemination;GO:0007600//sensory perception;GO:0019229//regulation of vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033555//multicellular organismal response to stress;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0051705//multi-organism behavior;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0010631//epithelial cell migration;GO:0007612//learning;GO:0014832//urinary bladder smooth muscle contraction;GO:0030278//regulation of ossification;GO:0045987//positive regulation of smooth muscle contraction;GO:0006954//inflammatory response;GO:0014072//response to isoquinoline alkaloid;GO:0007271//synaptic transmission, cholinergic;GO:0009719//response to endogenous stimulus;GO:0007613//memory;GO:0007631//feeding behavior;GO:0001508//action potential;GO:0032233//positive regulation of actin filament bundle assembly","K04222//tachykinin receptor 1","gi|6981628|ref|NP_036799.1|//substance-P receptor [Rattus norvegicus]"]
[null,24903,1674,82629.9110744457,360126.818080058,-2.12376901850683,"DOWN",{"v":9.03115690567604e-10,"d":"9.03E-10"},"Kng1","GO:0044421//extracellular region part;GO:0043025//neuronal cell body","GO:0004866//endopeptidase inhibitor activity;GO:0019899//enzyme binding","GO:0010466//negative regulation of peptidase activity;GO:0007596//blood coagulation;GO:0050880//regulation of blood vessel size;GO:0043405//regulation of MAP kinase activity;GO:0002526//acute inflammatory response;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0030162//regulation of proteolysis;GO:0001935//endothelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K03898//kininogen","gi|80861401|ref|NP_036828.2|//T-kininogen 1 precursor [Rattus norvegicus]"]
[null,24907,2019,36.2507779042716,80.7995225266236,-1.15633481339349,"DOWN",0.00803162476708546,"Dmd","GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044463//cell projection part;GO:0031674//I band","GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0001948//glycoprotein binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0005198//structural molecule activity;GO:0019899//enzyme binding","GO:0014706//striated muscle tissue development;GO:0048513//animal organ development;GO:0006936//muscle contraction;GO:0006518//peptide metabolic process;GO:0043112//receptor metabolic process;GO:0006351//transcription, DNA-templated;GO:0021604//cranial nerve structural organization;GO:0019725//cellular homeostasis;GO:0048858//cell projection morphogenesis","K10366//dystrophin","gi|52630318|ref|NP_036830.2|//dystrophin isoform Dp71a [Rattus norvegicus];gi|52630316|ref|NP_001005244.1|//dystrophin isoform Dp71ab [Rattus norvegicus];gi|957949291|gb|ALQ33490.1|//dystrophin isoform 4, partial [Homo sapiens]"]
[null,24914,1808,2.29354081869472,6.2112478652804,-1.43730655730404,"DOWN",0.0409077890516119,"Lox","GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix","GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046914//transition metal ion binding","GO:0009611//response to wounding;GO:0001944//vasculature development;GO:0008152//metabolic process;GO:0085029//extracellular matrix assembly;GO:0009725//response to hormone;GO:0030323//respiratory tube development","K00277//protein-lysine 6-oxidase [EC:1.4.3.13]","gi|8393733|ref|NP_058757.1|//protein-lysine 6-oxidase precursor [Rattus norvegicus]"]
[null,24932,3235,530.479787187524,1259.13864266876,-1.24706745925764,"DOWN",{"v":7.3224390921499e-06,"d":"7.32E-06"},"Cd4","GO:0005788//endoplasmic reticulum lumen;GO:0009897//external side of plasma membrane;GO:0031090//organelle membrane;GO:0044432//endoplasmic reticulum part;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:1990782//protein tyrosine kinase binding;GO:0019865//immunoglobulin binding;GO:0015026//coreceptor activity;GO:0042803//protein homodimerization activity;GO:0042289//MHC class II protein binding;GO:0019900//kinase binding;GO:0008270//zinc ion binding;GO:0001948//glycoprotein binding","GO:0050863//regulation of T cell activation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050829//defense response to Gram-negative bacterium;GO:0035397//helper T cell enhancement of adaptive immune response;GO:0032507//maintenance of protein location in cell;GO:0045185//maintenance of protein location;GO:0042102//positive regulation of T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0019058//viral life cycle;GO:0032355//response to estradiol;GO:0010033//response to organic substance;GO:0006948//induction by virus of host cell-cell fusion;GO:0001934//positive regulation of protein phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0030098//lymphocyte differentiation;GO:0033280//response to vitamin D;GO:0001816//cytokine production;GO:0045058//T cell selection;GO:0006497//protein lipidation;GO:0009967//positive regulation of signal transduction;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0033674//positive regulation of kinase activity;GO:0019048//modulation by virus of host morphology or physiology","K06454//T-cell surface glycoprotein CD4","gi|6978631|ref|NP_036837.1|//T-cell surface glycoprotein CD4 precursor [Rattus norvegicus]"]
[null,24936,1162,58.5645010797589,138.914025264406,-1.24609392249246,"DOWN",0.0121993971743675,"Cd9","GO:0030667//secretory granule membrane;GO:0044459//plasma membrane part;GO:0016021//integral component of membrane","GO:0005102//receptor binding","GO:0007043//cell-cell junction assembly;GO:0006950//response to stress;GO:0007417//central nervous system development;GO:0021782//glial cell development;GO:0001775//cell activation;GO:0008283//cell proliferation;GO:0007338//single fertilization;GO:0007599//hemostasis;GO:0006887//exocytosis","K06460//CD9 antigen","gi|148229054|ref|NP_444177.1|//CD9 antigen [Rattus norvegicus]"]
[null,24963,2632,2.37250765238909,6.15652419365099,-1.37570333373613,"DOWN",0.0495084479716517,"Hspa1l","GO:0044429//mitochondrial part","GO:0032559//adenyl ribonucleotide binding","GO:0048232//male gamete generation;GO:0050896//response to stimulus","K03283//heat shock 70kDa protein 1/8","gi|47087121|ref|NP_997711.1|//heat shock 70 kDa protein 1-like [Rattus norvegicus]"]
[null,24973,1566,860.707796694956,1897.82782139822,-1.14075366856951,"DOWN",0.0178962427918312,"RT1-A1","GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0042611//MHC protein complex","GO:0046983//protein dimerization activity","GO:0002484//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway;GO:0001911//negative regulation of leukocyte mediated cytotoxicity;GO:0002462//tolerance induction to nonself antigen","K06751//major histocompatibility complex, class I","gi|57012424|ref|NP_001008827.1|//RT1 class Ia, locus A1 precursor [Rattus norvegicus]"]
[null,24988,1035,18.6165346816514,44.2097235750592,-1.24777916195298,"DOWN",0.0288723568926889,"RT1-M2","GO:0031224//intrinsic component of membrane;GO:0042611//MHC protein complex","NA","GO:0002376//immune system process","K06751//major histocompatibility complex, class I","gi|48843735|ref|NP_001001717.1|//RT1 class Ib, locus M2 precursor [Rattus norvegicus]"]
[null,25021,3833,24.7958969093991,101.413108810734,-2.03207083320242,"DOWN",{"v":6.10382332663295e-05,"d":"6.10E-05"},"Itgam","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane","GO:0046982//protein heterodimerization activity;GO:0001846//opsonin binding;GO:0046983//protein dimerization activity;GO:0043394//proteoglycan binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0004871//signal transducer activity","GO:0050798//activated T cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0045123//cellular extravasation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0014005//microglia development;GO:0042098//T cell proliferation;GO:0007229//integrin-mediated signaling pathway","K06461//integrin alpha M","gi|29789036|ref|NP_036843.1|//integrin alpha-M precursor [Rattus norvegicus];gi|132626295|ref|NP_032427.2|//integrin alpha-M isoform 2 precursor [Mus musculus]"]
[null,25043,3615,27.6969615443156,104.078351368565,-1.90987039337431,"DOWN",0.000236280018001999,"Eln","NA","NA","NA","K14211//elastin","gi|674078310|ref|XP_008846618.1|//PREDICTED: elastin [Nannospalax galili]"]
[null,25059,3633,11.5267051545996,49.536606440158,-2.10351485309609,"DOWN",0.00034941257585652,"Hk2","GO:0031966//mitochondrial membrane","GO:0032559//adenyl ribonucleotide binding;GO:0048029//monosaccharide binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor","GO:0016310//phosphorylation;GO:0007589//body fluid secretion;GO:0006007//glucose catabolic process;GO:0010827//regulation of glucose transport;GO:0006915//apoptotic process","K00844//hexokinase [EC:2.7.1.1]","gi|7549765|ref|NP_036867.1|//hexokinase-2 [Rattus norvegicus]"]
[null,25100,1496,347.738833153078,699.649905347914,-1.00862901234541,"DOWN",{"v":4.80879939376621e-05,"d":"4.81E-05"},"Foxa3","GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044446//intracellular organelle part","GO:0043566//structure-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding","GO:0060897//neural plate regionalization;GO:0048232//male gamete generation;GO:0007417//central nervous system development;GO:0042593//glucose homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0001708//cell fate specification;GO:0006325//chromatin organization;GO:0045597//positive regulation of cell differentiation;GO:0031669//cellular response to nutrient levels","K08038//forkhead box protein A3, hepatocyte nuclear factor 3-gamma","gi|8393541|ref|NP_058773.1|//hepatocyte nuclear factor 3-gamma [Rattus norvegicus]"]
[null,25123,1386,108.889282100618,218.066602700962,-1.00190687797958,"DOWN",0.0365066796481479,"Tagln","GO:0044424//intracellular part;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0051015//actin filament binding;GO:0030674//protein binding, bridging","GO:0048513//animal organ development;GO:0007010//cytoskeleton organization;GO:0006996//organelle organization;GO:0030855//epithelial cell differentiation","K20526//transgelin","gi|674082951|ref|XP_008849145.1|//PREDICTED: transgelin isoform X1 [Nannospalax galili]"]
[null,25146,1711,825.93445944734,338.1436524012,1.28839103181252,"UP",0.0328081320267924,"Cyp17a1","GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044297//cell body;GO:0005739//mitochondrion","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004508//steroid 17-alpha-monooxygenase activity;GO:0047442//17-alpha-hydroxyprogesterone aldolase activity","GO:0021543//pallium development;GO:0006704//glucocorticoid biosynthetic process;GO:0042537//benzene-containing compound metabolic process;GO:0006950//response to stress;GO:0032496//response to lipopolysaccharide;GO:0007292//female gamete generation;GO:0006066//alcohol metabolic process;GO:0055114//oxidation-reduction process;GO:0009636//response to toxic substance;GO:0008406//gonad development;GO:0046677//response to antibiotic;GO:0018904//ether metabolic process;GO:0033189//response to vitamin A;GO:0042448//progesterone metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0035270//endocrine system development;GO:0007548//sex differentiation;GO:0009314//response to radiation;GO:0006700//C21-steroid hormone biosynthetic process;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0010893//positive regulation of steroid biosynthetic process","K00512//steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]","gi|6978731|ref|NP_036885.1|//steroid 17-alpha-hydroxylase/17,20 lyase precursor [Rattus norvegicus];gi|160948601|ref|NP_031835.3|//steroid 17-alpha-hydroxylase/17,20 lyase precursor [Mus musculus]"]
[null,25156,2851,94.8105224050247,208.718168424959,-1.13843710068074,"DOWN",0.000432363934006997,"Vav1","GO:0016020//membrane;GO:0005911//cell-cell junction;GO:0005622//intracellular;GO:0044444//cytoplasmic part","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0045785//positive regulation of cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0006897//endocytosis;GO:0007229//integrin-mediated signaling pathway;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0030155//regulation of cell adhesion;GO:0048468//cell development;GO:0006909//phagocytosis;GO:0030098//lymphocyte differentiation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0008361//regulation of cell size;GO:0072593//reactive oxygen species metabolic process;GO:0007266//Rho protein signal transduction;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0035023//regulation of Rho protein signal transduction;GO:0030217//T cell differentiation","K05730//guanine nucleotide exchange factor VAV","gi|162287067|ref|NP_036891.2|//proto-oncogene vav [Rattus norvegicus]"]
[null,25204,5046,24.5465982502147,167.216869266571,-2.76812538754083,"DOWN",{"v":1.87509875105315e-13,"d":"1.88E-13"},"Pcsk1","GO:0044421//extracellular region part;GO:0005783//endoplasmic reticulum;GO:0044297//cell body;GO:0033267//axon part;GO:0016023//null;GO:0044431//Golgi apparatus part","GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding","GO:0009746//response to hexose;GO:0006518//peptide metabolic process;GO:0034097//response to cytokine;GO:0002237//response to molecule of bacterial origin;GO:0030073//insulin secretion;GO:0048522//positive regulation of cellular process;GO:0006807//nitrogen compound metabolic process;GO:0009058//biosynthetic process;GO:0010038//response to metal ion;GO:0009611//response to wounding;GO:0009991//response to extracellular stimulus;GO:0033993//response to lipid;GO:0021536//diencephalon development;GO:0015980//energy derivation by oxidation of organic compounds;GO:0014072//response to isoquinoline alkaloid;GO:0031960//response to corticosteroid","K01359//proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]","gi|8393919|ref|NP_058787.1|//neuroendocrine convertase 1 precursor [Rattus norvegicus]"]
[null,25236,1176,7.15285304528314,27.5095575572015,-1.94334222972715,"DOWN",0.00291853474274205,"Gpc3","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005764//lysosome;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0000323//lytic vacuole","GO:0043395//heparan sulfate proteoglycan binding;GO:0060422//peptidyl-dipeptidase inhibitor activity;GO:0005515//protein binding;GO:0043394//proteoglycan binding;GO:0030414//peptidase inhibitor activity","GO:0030324//lung development;GO:0072203//cell proliferation involved in metanephros development;GO:0045926//negative regulation of growth;GO:0008589//regulation of smoothened signaling pathway;GO:0040008//regulation of growth;GO:0030100//regulation of endocytosis;GO:0030316//osteoclast differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0045807//positive regulation of endocytosis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0046326//positive regulation of glucose import;GO:0008283//cell proliferation;GO:0051346//negative regulation of hydrolase activity;GO:0072171//mesonephric tubule morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060976//coronary vasculature development;GO:0010466//negative regulation of peptidase activity;GO:0030282//bone mineralization;GO:0035116//embryonic hindlimb morphogenesis;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0030509//BMP signaling pathway;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0072180//mesonephric duct morphogenesis;GO:0009896//positive regulation of catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0010171//body morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0009948//anterior/posterior axis specification","K08109//glypican 3","gi|149060136|gb|EDM10952.1|//glypican 3 [Rattus norvegicus];gi|6980976|ref|NP_036906.1|//glypican-3 precursor [Rattus norvegicus]"]
[null,25256,2071,1281.86579335497,542.677534228165,1.24007813466539,"UP",0.00784707153926474,"Fmo1","GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0000166//nucleotide binding;GO:0050662//coenzyme binding","GO:0006950//response to stress;GO:0044237//cellular metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0055114//oxidation-reduction process;GO:0019748//secondary metabolic process","K00485//dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]","gi|537153454|gb|ERE72484.1|//dimethylaniline monooxygenase [N-oxide-forming] 1 [Cricetulus griseus];gi|6978847|ref|NP_036924.1|//dimethylaniline monooxygenase [N-oxide-forming] 1 [Rattus norvegicus]"]
[null,25290,2535,2.13788720999617,5.70894254797741,-1.41703780202506,"DOWN",0.0397125139052881,"Alox5","GO:0034399//nuclear periphery;GO:0005635//nuclear envelope;GO:0005886//plasma membrane;GO:0044444//cytoplasmic part;GO:0043005//neuron projection","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046914//transition metal ion binding","GO:0006691//leukotriene metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0019229//regulation of vasoconstriction;GO:0007600//sensory perception;GO:0031667//response to nutrient levels;GO:0002538//arachidonic acid metabolite production involved in inflammatory response","K00461//arachidonate 5-lipoxygenase [EC:1.13.11.34]","gi|6978493|ref|NP_036954.1|//arachidonate 5-lipoxygenase [Rattus norvegicus]"]
[null,25291,3444,482.782700953419,971.927683954083,-1.00947499200666,"DOWN",{"v":4.74025632191277e-05,"d":"4.74E-05"},"Anxa3","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0042581//specific granule;GO:0030670//phagocytic vesicle membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0030141//secretory granule;GO:0044297//cell body;GO:0005886//plasma membrane","GO:0004859//phospholipase inhibitor activity;GO:0019834//phospholipase A2 inhibitor activity;GO:0046872//metal ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0005543//phospholipid binding","GO:0021543//pallium development;GO:0031100//animal organ regeneration;GO:0002283//neutrophil activation involved in immune response;GO:0021766//hippocampus development;GO:0010595//positive regulation of endothelial cell migration;GO:0051054//positive regulation of DNA metabolic process;GO:0042742//defense response to bacterium;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006897//endocytosis;GO:0043312//neutrophil degranulation;GO:0043086//negative regulation of catalytic activity;GO:0045766//positive regulation of angiogenesis;GO:0010594//regulation of endothelial cell migration;GO:0051384//response to glucocorticoid;GO:0043388//positive regulation of DNA binding;GO:0006909//phagocytosis;GO:0031960//response to corticosteroid;GO:0009887//animal organ morphogenesis;GO:0010604//positive regulation of macromolecule metabolic process;GO:0045765//regulation of angiogenesis;GO:0070848//response to growth factor;GO:0006952//defense response","K17089//annexin A3","gi|401709965|ref|NP_036955.2|//annexin A3 [Rattus norvegicus];gi|507539039|ref|XP_004653533.1|//PREDICTED: annexin A3 [Jaculus jaculus]"]
[null,25314,2685,66.0267132996921,143.782701809788,-1.12276838076994,"DOWN",0.00778953861343788,"Emp1","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0032060//bleb assembly;GO:0040007//growth;GO:0008219//cell death;GO:0016049//cell growth","K19289//peripheral myelin protein 22","gi|6978807|ref|NP_036975.1|//epithelial membrane protein 1 [Rattus norvegicus]"]
[null,25315,1744,19912.5339924215,9214.93572652868,1.11163081624193,"UP",0.0204746726495994,"Ephx1","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0005515//protein binding;GO:0016803//ether hydrolase activity","GO:0006725//cellular aromatic compound metabolic process;GO:0051384//response to glucocorticoid","K01253//microsomal epoxide hydrolase [EC:3.3.2.9]","gi|77539442|ref|NP_001029262.1|//epoxide hydrolase 1 precursor [Rattus norvegicus]"]
[null,25333,521,28.4580211852224,66.797574309979,-1.2309603653119,"DOWN",0.0269136334038807,"Mgp","GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0044421//extracellular region part","GO:0046872//metal ion binding;GO:0005515//protein binding","GO:0009888//tissue development;GO:0065003//macromolecular complex assembly;GO:0030323//respiratory tube development;GO:0030278//regulation of ossification;GO:0001763//morphogenesis of a branching structure;GO:0048869//cellular developmental process;GO:0031960//response to corticosteroid;GO:0031667//response to nutrient levels;GO:0010038//response to metal ion","K19481//matrix Gla protein","gi|149049143|gb|EDM01597.1|//matrix Gla protein, isoform CRA_b [Rattus norvegicus]"]
[null,25341,2832,53.2899620984355,113.301408881762,-1.08823008879309,"DOWN",0.0121355319258965,"Tnfrsf11b","GO:0031012//extracellular matrix","GO:0005102//receptor binding;GO:0004871//signal transducer activity","GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0043062//extracellular structure organization;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048545//response to steroid hormone;GO:0012501//programmed cell death;GO:0031667//response to nutrient levels;GO:0032845//negative regulation of homeostatic process;GO:0023052//signaling;GO:0010038//response to metal ion","K05148//tumor necrosis factor receptor superfamily member 11B","gi|6981306|ref|NP_037002.1|//tumor necrosis factor receptor superfamily member 11B precursor [Rattus norvegicus]"]
[null,25353,1503,13.1549283185036,44.7129158561368,-1.76508824393839,"DOWN",0.00156456628976846,"Spp1","GO:0044421//extracellular region part;GO:0044444//cytoplasmic part;GO:0031982//vesicle","GO:0005102//receptor binding","GO:0048671//negative regulation of collateral sprouting;GO:0006952//defense response;GO:0009725//response to hormone;GO:0010810//regulation of cell-substrate adhesion;GO:0043066//negative regulation of apoptotic process;GO:0033273//response to vitamin;GO:0001503//ossification;GO:0032846//positive regulation of homeostatic process","K06250//secreted phosphoprotein 1","gi|145046230|ref|NP_037013.2|//osteopontin precursor [Rattus norvegicus]"]
[null,25358,4035,248.514783020418,505.605539488182,-1.02468059623643,"DOWN",0.0183812788620404,"Timp3","GO:0070062//extracellular exosome;GO:0044424//intracellular part;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0007399//nervous system development;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:0043200//response to amino acid;GO:0001101//response to acid chemical;GO:0009888//tissue development;GO:0043627//response to estrogen;GO:0042246//tissue regeneration;GO:0071310//cellular response to organic substance;GO:0030162//regulation of proteolysis;GO:0050953//sensory perception of light stimulus;GO:0051593//response to folic acid;GO:1904684//negative regulation of metalloendopeptidase activity;GO:0012502//induction of programmed cell death;GO:0009605//response to external stimulus;GO:0031330//negative regulation of cellular catabolic process;GO:0010466//negative regulation of peptidase activity;GO:0009612//response to mechanical stimulus;GO:0007417//central nervous system development;GO:0007568//aging;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0048545//response to steroid hormone;GO:0009725//response to hormone;GO:0051045//negative regulation of membrane protein ectodomain proteolysis","K16866//metalloproteinase inhibitor 3","gi|67972654|ref|NP_037018.2|//metalloproteinase inhibitor 3 precursor [Rattus norvegicus]"]
[null,25380,1401,59.312582127326,141.347201139834,-1.25283323131658,"DOWN",0.00141240631749643,"Anxa1","GO:0005740//mitochondrial envelope;GO:0032991//macromolecular complex;GO:0005856//cytoskeleton;GO:0044421//extracellular region part;GO:0042995//cell projection;GO:0044459//plasma membrane part","GO:0004859//phospholipase inhibitor activity;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005543//phospholipid binding","GO:0034614//cellular response to reactive oxygen species;GO:0034097//response to cytokine;GO:0043627//response to estrogen;GO:0022008//neurogenesis;GO:0008283//cell proliferation;GO:0048523//negative regulation of cellular process;GO:0001516//prostaglandin biosynthetic process;GO:0015909//long-chain fatty acid transport;GO:0022602//ovulation cycle process;GO:0009913//epidermal cell differentiation;GO:0030072//peptide hormone secretion;GO:0007165//signal transduction;GO:0010212//response to ionizing radiation;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0031960//response to corticosteroid;GO:0031016//pancreas development;GO:0019222//regulation of metabolic process;GO:0006906//vesicle fusion;GO:0006464//cellular protein modification process","K17091//annexin A1","gi|564333152|ref|XP_006231221.1|//PREDICTED: annexin A1 isoform X2 [Rattus norvegicus]"]
[null,25404,2584,28.2949949945395,78.4205270928919,-1.47068445656123,"DOWN",0.000579442863019169,"Cav1","GO:0012505//endomembrane system;GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005924//cell-substrate adherens junction","GO:0000149//SNARE binding;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity","GO:0014706//striated muscle tissue development;GO:0007596//blood coagulation;GO:0048732//gland development;GO:0030301//cholesterol transport;GO:0043405//regulation of MAP kinase activity;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0031294//lymphocyte costimulation;GO:0031669//cellular response to nutrient levels;GO:0051259//protein oligomerization;GO:0001935//endothelial cell proliferation;GO:0043393//regulation of protein binding;GO:0051345//positive regulation of hydrolase activity;GO:0030509//BMP signaling pathway;GO:0006639//acylglycerol metabolic process;GO:0031960//response to corticosteroid;GO:0001933//negative regulation of protein phosphorylation;GO:0006898//receptor-mediated endocytosis;GO:0048771//tissue remodeling;GO:0007589//body fluid secretion;GO:0019229//regulation of vasoconstriction;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030100//regulation of endocytosis;GO:0045185//maintenance of protein location;GO:0006937//regulation of muscle contraction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006631//fatty acid metabolic process;GO:0001765//membrane raft assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0042391//regulation of membrane potential;GO:0033483//gas homeostasis;GO:0000165//MAPK cascade;GO:0010212//response to ionizing radiation;GO:0031112//positive regulation of microtubule polymerization or depolymerization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0055092//sterol homeostasis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation","K06278//caveolin 1","gi|984104888|ref|XP_015343756.1|//PREDICTED: caveolin-1 [Marmota marmota marmota];gi|189083698|ref|NP_113744.2|//caveolin-1 isoform alpha [Rattus norvegicus]"]
[null,25413,2296,2975.12466425118,1455.54391658634,1.03139175274662,"UP",0.0293482421907432,"Cpt2","GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane","GO:0016406//carnitine O-acyltransferase activity","GO:0019217//regulation of fatty acid metabolic process;GO:0015908//fatty acid transport;GO:0003333//amino acid transmembrane transport;GO:0009062//fatty acid catabolic process","K08766//carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]","gi|6978705|ref|NP_037062.1|//carnitine O-palmitoyltransferase 2, mitochondrial precursor [Rattus norvegicus]"]
[null,25418,5230,36.5572988150897,93.4638015692071,-1.35424824398691,"DOWN",0.00307986462380339,"Dpysl3","GO:0044421//extracellular region part;GO:0030427//site of polarized growth;GO:0030133//transport vesicle","GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0019904//protein domain specific binding;GO:0005539//glycosaminoglycan binding","GO:0023052//signaling;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development","K07528//dihydropyrimidinase-like 2","gi|25742568|ref|NP_037066.1|//dihydropyrimidinase-related protein 3 [Rattus norvegicus];gi|950961799|ref|XP_014453102.1|//PREDICTED: dihydropyrimidinase-related protein 3 isoform X1 [Alligator mississippiensis] "]
[null,25429,2626,39.7022643290268,86.2823822740462,-1.11984471958073,"DOWN",0.00976774577763291,"Cyp7b1","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0008395//steroid hydroxylase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding","GO:0006694//steroid biosynthetic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0002009//morphogenesis of an epithelium;GO:0010033//response to organic substance;GO:0016125//sterol metabolic process;GO:0048511//rhythmic process;GO:0007611//learning or memory;GO:0008284//positive regulation of cell proliferation","K07430//25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]","gi|158186667|ref|NP_062011.1|//25-hydroxycholesterol 7-alpha-hydroxylase [Rattus norvegicus]"]
[null,25434,2676,95.3016775296126,193.474567099313,-1.02157041734715,"DOWN",0.0100730773860362,"Sparcl1","GO:0031012//extracellular matrix","GO:0046872//metal ion binding","GO:0023052//signaling","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican);K12819//pre-mRNA-processing factor SLU7","gi|6978789|ref|NP_037078.1|//SPARC-like protein 1 precursor [Rattus norvegicus]"]
[null,25472,1577,79.7817098764433,161.604931773869,-1.01834127755023,"DOWN",0.0248250719246145,"Kcnj8","GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0043292//contractile fiber","GO:0032559//adenyl ribonucleotide binding;GO:0005242//inward rectifier potassium channel activity","GO:0043331//response to dsRNA;GO:0048513//animal organ development;GO:0050880//regulation of blood vessel size;GO:0002252//immune effector process;GO:0071805//potassium ion transmembrane transport;GO:0002237//response to molecule of bacterial origin;GO:0009628//response to abiotic stimulus","K05001//potassium inwardly-rectifying channel subfamily J member 8","gi|148747200|ref|NP_058795.3|//ATP-sensitive inward rectifier potassium channel 8 [Rattus norvegicus]"]
[null,25475,879,33.8226683728464,93.557781125772,-1.46786716342439,"DOWN",0.0115855964979504,"Lgals5","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0060089//molecular transducer activity;GO:0048030//disaccharide binding;GO:0016936//galactoside binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0005102//receptor binding;GO:0004871//signal transducer activity;GO:0019899//enzyme binding","GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0060135//maternal process involved in female pregnancy;GO:1902715//positive regulation of interferon-gamma secretion;GO:0043305//negative regulation of mast cell degranulation;GO:0043322//negative regulation of natural killer cell degranulation;GO:1900426//positive regulation of defense response to bacterium;GO:0034134//toll-like receptor 2 signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0033081//regulation of T cell differentiation in thymus;GO:2001184//positive regulation of interleukin-12 secretion;GO:0070555//response to interleukin-1;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:2000406//positive regulation of T cell migration;GO:0032753//positive regulation of interleukin-4 production;GO:2000778//positive regulation of interleukin-6 secretion;GO:1902714//negative regulation of interferon-gamma secretion;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0043032//positive regulation of macrophage activation;GO:0032674//regulation of interleukin-5 production;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:0010628//positive regulation of gene expression;GO:0002519//natural killer cell tolerance induction;GO:0046598//positive regulation of viral entry into host cell;GO:1904469//positive regulation of tumor necrosis factor secretion;GO:2000316//regulation of T-helper 17 type immune response;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0010819//regulation of T cell chemotaxis;GO:0098586//cellular response to virus;GO:0046007//negative regulation of activated T cell proliferation;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000667//positive regulation of interleukin-13 secretion;GO:1900744//regulation of p38MAPK cascade;GO:0045185//maintenance of protein location;GO:0010629//negative regulation of gene expression;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032496//response to lipopolysaccharide;GO:0032823//regulation of natural killer cell differentiation;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0097029//mature conventional dendritic cell differentiation;GO:0051353//positive regulation of oxidoreductase activity;GO:0032834//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response;GO:2001181//positive regulation of interleukin-10 secretion;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070241//positive regulation of activated T cell autonomous cell death;GO:0032682//negative regulation of chemokine production;GO:0006811//ion transport;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:2000484//positive regulation of interleukin-8 secretion;GO:0071636//positive regulation of transforming growth factor beta production;GO:2001190//positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2001200//positive regulation of dendritic cell differentiation","K17522//galectin-5;K10093//galectin-9","gi|149053564|gb|EDM05381.1|//rCG35210 [Rattus norvegicus];gi|6981154|ref|NP_037108.1|//galectin-5 [Rattus norvegicus]"]
[null,25505,2547,12.7262578645492,30.975568589663,-1.28332250535323,"DOWN",0.0340024489410034,"P2rx1","GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0009279//cell outer membrane","GO:0016502//nucleotide receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0032559//adenyl ribonucleotide binding;GO:0046914//transition metal ion binding","GO:0042310//vasoconstriction;GO:0006915//apoptotic process;GO:0006672//ceramide metabolic process;GO:0006940//regulation of smooth muscle contraction;GO:0007620//copulation;GO:0001775//cell activation;GO:0010959//regulation of metal ion transport;GO:0035587//purinergic receptor signaling pathway;GO:0001508//action potential;GO:0010033//response to organic substance;GO:0007270//neuron-neuron synaptic transmission;GO:0002442//serotonin secretion involved in inflammatory response;GO:0051259//protein oligomerization","K05215//P2X purinoceptor 1","gi|215276993|ref|NP_001135839.1|//P2X purinoceptor 1 isoform 2 [Rattus norvegicus];gi|549806796|ref|NP_001272344.1|//P2X purinoceptor 1 isoform 3 [Rattus norvegicus];gi|6981320|ref|NP_037129.1|//P2X purinoceptor 1 isoform 1 [Rattus norvegicus]"]
[null,25528,3846,591.004618738985,1400.57812237781,-1.24478114694636,"DOWN",0.000340113985361777,"Sirpa","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0019904//protein domain specific binding;GO:0045309//protein phosphorylated amino acid binding;GO:0017124//SH3 domain binding;GO:0051219//phosphoprotein binding","GO:0006911//phagocytosis, engulfment;GO:0002244//hematopoietic progenitor cell differentiation;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0006910//phagocytosis, recognition;GO:0031589//cell-substrate adhesion;GO:0045807//positive regulation of endocytosis;GO:0050766//positive regulation of phagocytosis;GO:0007160//cell-matrix adhesion;GO:0007015//actin filament organization;GO:0048870//cell motility;GO:0006909//phagocytosis","K06551//signal-regulatory protein alpha/beta1/gamma","gi|31543529|ref|NP_037148.2|//tyrosine-protein phosphatase non-receptor type substrate 1 precursor [Rattus norvegicus];gi|149023273|gb|EDL80167.1|//protein tyrosine phosphatase, non-receptor type substrate 1, isoform CRA_b [Rattus norvegicus];gi|29427383|sp|P97710.1|SHPS1_RAT//RecName: Full=Tyrosine-protein phosphatase non-receptor type substrate 1; Short=SHP substrate 1; Short=SHPS-1; AltName: Full=Brain Ig-like molecule with tyrosine-based activation motifs; Short=Bit; AltName: Full=CD172 antigen-like family member A; AltName: Full=Inhibitory receptor SHPS-1; AltName: Full=Macrophage fusion receptor; AltName: Full=Macrophage membrane protein MFP150; AltName: Full=Signal-regulatory protein alpha-1; Short=Sirp-alpha-1; AltName: CD_antigen=CD172a; Flags: Precursor"]
[null,25559,1767,116.299233655659,35.6032950561102,1.70775891758043,"UP",0.000184781289198963,"Abcc8","GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0030672//synaptic vesicle membrane;GO:0042383//sarcolemma;GO:0008076//voltage-gated potassium channel complex","GO:0000149//SNARE binding;GO:0015405//P-P-bond-hydrolysis-driven transmembrane transporter activity;GO:0005524//ATP binding;GO:0005267//potassium channel activity;GO:0005261//cation channel activity;GO:0044325//ion channel binding;GO:0032559//adenyl ribonucleotide binding;GO:0004888//transmembrane signaling receptor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0019905//syntaxin binding","GO:0006813//potassium ion transport;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:0043434//response to peptide hormone;GO:0010043//response to zinc ion;GO:0002237//response to molecule of bacterial origin;GO:0009628//response to abiotic stimulus;GO:0050796//regulation of insulin secretion;GO:0071310//cellular response to organic substance;GO:0043268//positive regulation of potassium ion transport;GO:0046676//negative regulation of insulin secretion;GO:0010038//response to metal ion;GO:0009207//purine ribonucleoside triphosphate catabolic process","K05032//ATP-binding cassette subfamily C (CFTR/MRP) member 8","gi|672036284|ref|XP_008757541.1|//PREDICTED: ATP-binding cassette sub-family C member 8 isoform X1 [Rattus norvegicus];gi|568947586|ref|XP_006540813.1|//PREDICTED: ATP-binding cassette sub-family C member 8 isoform X9 [Mus musculus];gi|148368981|ref|NP_037171.2|//ATP-binding cassette sub-family C member 8 [Rattus norvegicus]"]
[null,25560,4848,200.173480308957,549.765778106211,-1.45756625108233,"DOWN",0.0174256227551144,"Abcc9","GO:0043231//intracellular membrane-bounded organelle;GO:0030315//T-tubule;GO:0043229//intracellular organelle;GO:0008282//ATP-sensitive potassium channel complex;GO:0044425//membrane part;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0044444//cytoplasmic part;GO:0008076//voltage-gated potassium channel complex","GO:0000149//SNARE binding;GO:0005524//ATP binding;GO:0008144//drug binding;GO:0004888//transmembrane signaling receptor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0015459//potassium channel regulator activity;GO:0015405//P-P-bond-hydrolysis-driven transmembrane transporter activity;GO:0005267//potassium channel activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008281//sulfonylurea receptor activity;GO:0016247//channel regulator activity;GO:0005488//binding;GO:0005261//cation channel activity;GO:0044325//ion channel binding;GO:0032559//adenyl ribonucleotide binding;GO:0019905//syntaxin binding;GO:0022857//transmembrane transporter activity","GO:0006810//transport;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0042221//response to chemical;GO:0051607//defense response to virus;GO:0002252//immune effector process;GO:0006932//substrate-dependent cell migration, cell contraction;GO:0001667//ameboidal-type cell migration;GO:0010107//potassium ion import;GO:0023052//signaling;GO:0071805//potassium ion transmembrane transport;GO:0009207//purine ribonucleoside triphosphate catabolic process","K05033//ATP-binding cassette subfamily C (CFTR/MRP) member 9","gi|149049027|gb|EDM01481.1|//rCG30275, isoform CRA_f [Rattus norvegicus];gi|19923678|ref|NP_037172.2|//ATP-binding cassette sub-family C member 9 [Rattus norvegicus]"]
[null,25563,477,17.3500221032739,55.2446448951083,-1.67089712380181,"DOWN",0.0107169504647516,"Tff3","GO:0016023//null;GO:0033166//hyaline layer","NA","GO:0009611//response to wounding;GO:0009725//response to hormone","NA","gi|386869333|ref|NP_037174.2|//trefoil factor 3 precursor [Rattus norvegicus]"]
[null,25584,1798,7.3229824764612,19.3097408047402,-1.39882555041916,"DOWN",0.0280707633843448,"F3","GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part;GO:0044424//intracellular part","GO:0008289//lipid binding;GO:0019899//enzyme binding","GO:0009605//response to external stimulus;GO:0034614//cellular response to reactive oxygen species;GO:0014909//smooth muscle cell migration;GO:0002237//response to molecule of bacterial origin;GO:0009628//response to abiotic stimulus;GO:0043627//response to estrogen;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0072376//protein activation cascade;GO:0045765//regulation of angiogenesis;GO:0055094//response to lipoprotein particle;GO:0007599//hemostasis;GO:0001935//endothelial cell proliferation","K03901//coagulation factor III (tissue factor)","gi|52138595|ref|NP_037189.2|//tissue factor precursor [Rattus norvegicus]"]
[null,25599,1299,1908.55828582615,4554.07248857435,-1.25467400951284,"DOWN",0.00619893273899878,"Cd74","GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0042611//MHC protein complex;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0042613//MHC class II protein complex;GO:0005764//lysosome;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0009986//cell surface;GO:0035693//NOS2-CD74 complex;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0000323//lytic vacuole","GO:0001540//beta-amyloid binding;GO:0035718//macrophage migration inhibitory factor binding;GO:0004896//cytokine receptor activity;GO:0042658//MHC class II protein binding, via antigen binding groove;GO:0015293//symporter activity;GO:0042287//MHC protein binding;GO:0050998//nitric-oxide synthase binding;GO:0004888//transmembrane signaling receptor activity;GO:0019899//enzyme binding;GO:0044183//protein binding involved in protein folding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016064//immunoglobulin mediated immune response;GO:0009968//negative regulation of signal transduction;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0045580//regulation of T cell differentiation;GO:0002468//dendritic cell antigen processing and presentation;GO:0045060//negative thymic T cell selection;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0045581//negative regulation of T cell differentiation;GO:0015031//protein transport;GO:0001516//prostaglandin biosynthetic process;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0019724//B cell mediated immunity;GO:0030888//regulation of B cell proliferation;GO:0002901//mature B cell apoptotic process;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0048146//positive regulation of fibroblast proliferation;GO:0065003//macromolecular complex assembly;GO:0006886//intracellular protein transport;GO:0008643//carbohydrate transport;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0002478//antigen processing and presentation of exogenous peptide antigen;GO:0043383//negative T cell selection;GO:0010935//regulation of macrophage cytokine production;GO:0006461//protein complex assembly;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0045089//positive regulation of innate immune response;GO:0006950//response to stress;GO:0051084//'de novo' posttranslational protein folding;GO:0002790//peptide secretion;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0001934//positive regulation of protein phosphorylation;GO:0045582//positive regulation of T cell differentiation;GO:0060907//positive regulation of macrophage cytokine production;GO:0006814//sodium ion transport;GO:0002792//negative regulation of peptide secretion;GO:0055085//transmembrane transport;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0000187//activation of MAPK activity;GO:0035691//macrophage migration inhibitory factor signaling pathway;GO:0043368//positive T cell selection;GO:0002828//regulation of type 2 immune response;GO:0006693//prostaglandin metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002830//positive regulation of type 2 immune response;GO:0043410//positive regulation of MAPK cascade;GO:0045059//positive thymic T cell selection;GO:0002821//positive regulation of adaptive immune response;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032722//positive regulation of chemokine production;GO:0008284//positive regulation of cell proliferation","K06505//CD74 antigen","gi|6978637|ref|NP_037201.1|//H-2 class II histocompatibility antigen gamma chain [Rattus norvegicus];gi|123111|sp|P10247.2|HG2A_RAT//RecName: Full=H-2 class II histocompatibility antigen gamma chain; AltName: Full=Ia antigen-associated invariant chain; Short=Ii; AltName: Full=MHC class II-associated invariant chain; AltName: CD_antigen=CD74"]
[null,25602,1492,21.3269821640483,46.2736353380756,-1.117510609838,"DOWN",0.0387448478586286,"Tnxa-ps1","NA","NA","NA","K06252//tenascin","gi|195540030|gb|AAI68181.1|//Tnxb protein [Rattus norvegicus];gi|841426|gb|AAA91987.1|//tenascin-X, partial [Rattus norvegicus]"]
[null,25612,2531,276.361982751372,102.094279057374,1.43665714178068,"UP",0.0122817963548757,"Asns","GO:0044444//cytoplasmic part","GO:0032559//adenyl ribonucleotide binding;GO:0042802//identical protein binding;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor","GO:0009064//glutamine family amino acid metabolic process;GO:0034698//response to gonadotropin;GO:0014070//response to organic cyclic compound;GO:0007346//regulation of mitotic cell cycle;GO:0048513//animal organ development;GO:0009267//cellular response to starvation;GO:0001101//response to acid chemical;GO:0006915//apoptotic process;GO:0009314//response to radiation;GO:0006528//asparagine metabolic process","K01953//asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]","gi|149064973|gb|EDM15049.1|//asparagine synthetase, isoform CRA_a [Rattus norvegicus];gi|585640156|ref|XP_006880294.1|//PREDICTED: asparagine synthetase [glutamine-hydrolyzing]-like [Elephantulus edwardii]"]
[null,25619,2355,90.3736015328682,281.326163900538,-1.63827040976955,"DOWN",{"v":1.08297996767847e-06,"d":"1.08E-06"},"Plau","GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0044421//extracellular region part;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005925//focal adhesion","GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups","GO:0001952//regulation of cell-matrix adhesion;GO:0016310//phosphorylation;GO:0071222//cellular response to lipopolysaccharide;GO:0070997//neuron death;GO:0014909//smooth muscle cell migration;GO:0007566//embryo implantation;GO:0006796//phosphate-containing compound metabolic process;GO:0010469//regulation of receptor activity;GO:0060279//positive regulation of ovulation;GO:0042730//fibrinolysis;GO:2000345//regulation of hepatocyte proliferation;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0001525//angiogenesis;GO:0071333//cellular response to glucose stimulus;GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0019538//protein metabolic process;GO:0055093//response to hyperoxia;GO:0009966//regulation of signal transduction;GO:0048646//anatomical structure formation involved in morphogenesis;GO:2000097//regulation of smooth muscle cell-matrix adhesion;GO:0071456//cellular response to hypoxia;GO:0043403//skeletal muscle tissue regeneration;GO:0071498//cellular response to fluid shear stress;GO:0042246//tissue regeneration;GO:0007283//spermatogenesis;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0008283//cell proliferation;GO:0072734//cellular response to staurosporine;GO:0014911//positive regulation of smooth muscle cell migration;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0014823//response to activity;GO:0042221//response to chemical;GO:0008284//positive regulation of cell proliferation","K01348//urokinase plasminogen activator [EC:3.4.21.73]","gi|145207953|ref|NP_037217.3|//urokinase-type plasminogen activator precursor [Rattus norvegicus]"]
[null,25630,2451,329.666198808627,997.999422387075,-1.59803300776262,"DOWN",{"v":2.01118860592643e-05,"d":"2.01E-05"},"Pkm","GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005929//cilium;GO:0042995//cell projection;GO:0005634//nucleus;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0004743//pyruvate kinase activity;GO:0016301//kinase activity;GO:0023026//MHC class II protein complex binding;GO:0043531//ADP binding;GO:0030955//potassium ion binding;GO:0032559//adenyl ribonucleotide binding;GO:0031420//alkali metal ion binding","GO:0031100//animal organ regeneration;GO:0043403//skeletal muscle tissue regeneration;GO:0009206//purine ribonucleoside triphosphate biosynthetic process;GO:0006096//glycolytic process;GO:0009628//response to abiotic stimulus;GO:0042246//tissue regeneration;GO:0009629//response to gravity;GO:0006754//ATP biosynthetic process;GO:0042866//pyruvate biosynthetic process;GO:0007584//response to nutrient;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process;GO:0001889//liver development;GO:0014854//response to inactivity;GO:0006007//glucose catabolic process;GO:0032868//response to insulin;GO:0043434//response to peptide hormone;GO:0008219//cell death;GO:0001666//response to hypoxia;GO:0014870//response to muscle inactivity;GO:0009887//animal organ morphogenesis;GO:0031667//response to nutrient levels;GO:0012501//programmed cell death","K00873//pyruvate kinase [EC:2.7.1.40]","gi|537175787|gb|ERE74943.1|//pyruvate kinase isozymes M1/M2-like isoform 1 [Cricetulus griseus];gi|564364021|ref|XP_006243250.1|//PREDICTED: pyruvate kinase PKM isoform X2 [Rattus norvegicus];gi|564364019|ref|XP_006243249.1|//PREDICTED: pyruvate kinase PKM isoform X1 [Rattus norvegicus]"]
[null,25632,556,7174.06873267056,19888.3869072096,-1.47106279534199,"DOWN",0.00186207913000832,"Hba1","GO:0043234//protein complex;GO:0015935//small ribosomal subunit","GO:0016209//antioxidant activity;GO:0022892//substrate-specific transporter activity;GO:0005515//protein binding;GO:0005506//iron ion binding","GO:0008217//regulation of blood pressure;GO:0015669//gas transport;GO:0042743//hydrogen peroxide metabolic process;GO:0008219//cell death;GO:0043009//chordate embryonic development;GO:0051931//regulation of sensory perception;GO:0000302//response to reactive oxygen species;GO:0048468//cell development;GO:0051259//protein oligomerization","K13822//hemoglobin subunit alpha","gi|6981010|ref|NP_037228.1|//hemoglobin subunit alpha-1/2 [Rattus norvegicus]"]
[null,25634,2338,18841.5232519033,6787.01692422386,1.47306608926073,"UP",0.000146008326305985,"G6pc","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0022624//proteasome accessory complex","GO:0019203//carbohydrate phosphatase activity;GO:0043168//anion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups","GO:0006006//glucose metabolic process;GO:0006639//acylglycerol metabolic process;GO:0055092//sterol homeostasis;GO:0005977//glycogen metabolic process;GO:0033500//carbohydrate homeostasis;GO:0010467//gene expression;GO:0031667//response to nutrient levels;GO:0006082//organic acid metabolic process;GO:0016311//dephosphorylation;GO:0040007//growth;GO:0015712//hexose phosphate transport","K01084//glucose-6-phosphatase [EC:3.1.3.9]","gi|145207998|ref|NP_037230.2|//glucose-6-phosphatase [Rattus norvegicus];gi|504175781|ref|XP_004597401.1|//PREDICTED: glucose-6-phosphatase [Ochotona princeps]"]
[null,25649,827,34214.6394964928,15917.5183215258,1.103998321648,"UP",0.00860868708367532,"Apoa2","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0044432//endoplasmic reticulum part;GO:0034361//very-low-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0034385//triglyceride-rich lipoprotein particle","GO:0032934//sterol binding;GO:0070653//high-density lipoprotein particle receptor binding;GO:0055102//lipase inhibitor activity;GO:0015485//cholesterol binding;GO:0046982//protein heterodimerization activity;GO:0034190//apolipoprotein receptor binding;GO:0046983//protein dimerization activity;GO:0071813//lipoprotein particle binding;GO:0004857//enzyme inhibitor activity;GO:0031210//phosphatidylcholine binding;GO:0070325//lipoprotein particle receptor binding;GO:0042802//identical protein binding;GO:0017127//cholesterol transporter activity;GO:0042803//protein homodimerization activity;GO:0008035//high-density lipoprotein particle binding;GO:0005543//phospholipid binding;GO:0015248//sterol transporter activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0008047//enzyme activator activity","GO:0031100//animal organ regeneration;GO:0046470//phosphatidylcholine metabolic process;GO:0009746//response to hexose;GO:0034374//low-density lipoprotein particle remodeling;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0043627//response to estrogen;GO:0033344//cholesterol efflux;GO:0044267//cellular protein metabolic process;GO:0060695//negative regulation of cholesterol transporter activity;GO:0009749//response to glucose;GO:0016125//sterol metabolic process;GO:0051346//negative regulation of hydrolase activity;GO:0042157//lipoprotein metabolic process;GO:0006457//protein folding;GO:0009395//phospholipid catabolic process;GO:0042493//response to drug;GO:0030300//regulation of intestinal cholesterol absorption;GO:0050996//positive regulation of lipid catabolic process;GO:0009896//positive regulation of catabolic process;GO:0015759//beta-glucoside transport;GO:0031960//response to corticosteroid;GO:0032787//monocarboxylic acid metabolic process;GO:0009895//negative regulation of catabolic process;GO:0030299//intestinal cholesterol absorption;GO:0033700//phospholipid efflux;GO:0018158//protein oxidation;GO:0042946//glucoside transport;GO:0043691//reverse cholesterol transport;GO:0006656//phosphatidylcholine biosynthetic process;GO:0060192//negative regulation of lipase activity;GO:0008203//cholesterol metabolic process;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0010872//regulation of cholesterol esterification;GO:0060621//negative regulation of cholesterol import;GO:0050995//negative regulation of lipid catabolic process;GO:0034381//plasma lipoprotein particle clearance;GO:0015914//phospholipid transport;GO:0006631//fatty acid metabolic process;GO:0002740//negative regulation of cytokine secretion involved in immune response;GO:0042632//cholesterol homeostasis;GO:0051384//response to glucocorticoid;GO:0043085//positive regulation of catalytic activity;GO:0032375//negative regulation of cholesterol transport;GO:0034377//plasma lipoprotein particle assembly;GO:0034384//high-density lipoprotein particle clearance;GO:0046340//diacylglycerol catabolic process;GO:0002526//acute inflammatory response;GO:0034380//high-density lipoprotein particle assembly;GO:0002374//cytokine secretion involved in immune response;GO:0055092//sterol homeostasis;GO:0009887//animal organ morphogenesis;GO:0006952//defense response;GO:0034375//high-density lipoprotein particle remodeling;GO:0031647//regulation of protein stability;GO:0046339//diacylglycerol metabolic process;GO:0010901//regulation of very-low-density lipoprotein particle remodeling;GO:0045416//positive regulation of interleukin-8 biosynthetic process;GO:0018206//peptidyl-methionine modification;GO:0010873//positive regulation of cholesterol esterification","K08758//apolipoprotein A-II","gi|6978517|ref|NP_037244.1|//apolipoprotein A-II preproprotein [Rattus norvegicus]"]
[null,25650,2228,2711.58317828575,1080.28611587603,1.32772196237182,"UP",0.00983439817267313,"Atp1b1","GO:0005887//integral component of plasma membrane","GO:0008556//potassium-transporting ATPase activity;GO:0005488//binding","GO:0002376//immune system process;GO:0035725//sodium ion transmembrane transport;GO:0009206//purine ribonucleoside triphosphate biosynthetic process;GO:0006950//response to stress;GO:0007599//hemostasis;GO:0009207//purine ribonucleoside triphosphate catabolic process","K01540//sodium/potassium-transporting ATPase subunit beta","gi|148747253|ref|NP_037245.2|//sodium/potassium-transporting ATPase subunit beta-1 [Rattus norvegicus]"]
[null,25663,5010,2218.36830293055,5633.62559438127,-1.34456477895702,"DOWN",0.00034911608662652,"Il1r1","GO:0030424//axon;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0014069//postsynaptic density;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0070851//growth factor receptor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0004909//interleukin-1, Type I, activating receptor activity;GO:0035255//ionotropic glutamate receptor binding;GO:0004908//interleukin-1 receptor activity;GO:0019966//interleukin-1 binding","GO:0010286//heat acclimation;GO:2000661//positive regulation of interleukin-1-mediated signaling pathway;GO:0070849//response to epidermal growth factor;GO:0007292//female gamete generation;GO:0030728//ovulation;GO:0002376//immune system process;GO:0071559//response to transforming growth factor beta;GO:0071731//response to nitric oxide;GO:0050727//regulation of inflammatory response;GO:2000391//positive regulation of neutrophil extravasation;GO:0071333//cellular response to glucose stimulus;GO:0009314//response to radiation;GO:0006952//defense response;GO:0010035//response to inorganic substance;GO:0019221//cytokine-mediated signaling pathway;GO:2001224//positive regulation of neuron migration","K04386//interleukin 1 receptor type I","gi|149046287|gb|EDL99180.1|//interleukin 1 receptor, type I, isoform CRA_b [Rattus norvegicus];gi|148747433|ref|NP_037255.3|//interleukin-1 receptor type 1 [Rattus norvegicus]"]
[null,25668,2870,154.562555039477,345.516635435983,-1.1605643247264,"DOWN",0.000135095305378499,"Cd38","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003953//NAD+ nucleosidase activity;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016740//transferase activity;GO:0050135//NAD(P)+ nucleosidase activity","GO:0033194//response to hydroperoxide;GO:0022414//reproductive process;GO:0043627//response to estrogen;GO:0032570//response to progesterone;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0050796//regulation of insulin secretion;GO:0045779//negative regulation of bone resorption;GO:0030890//positive regulation of B cell proliferation;GO:0060292//long term synaptic depression;GO:0032355//response to estradiol;GO:0070555//response to interleukin-1;GO:0033189//response to vitamin A;GO:0030888//regulation of B cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0006979//response to oxidative stress;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0032024//positive regulation of insulin secretion;GO:0019229//regulation of vasoconstriction;GO:0034097//response to cytokine;GO:0030307//positive regulation of cell growth;GO:0016049//cell growth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045907//positive regulation of vasoconstriction;GO:0032845//negative regulation of homeostatic process;GO:0050853//B cell receptor signaling pathway;GO:0032526//response to retinoic acid;GO:0007204//positive regulation of cytosolic calcium ion concentration","K01242//ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]","gi|6978629|ref|NP_037259.1|//ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Rattus norvegicus]"]
[null,25679,8806,22.8052010258137,52.8267934571771,-1.21190695466811,"DOWN",0.0170314221923099,"Itpr3","GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0044297//cell body;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane","GO:0046873//metal ion transmembrane transporter activity;GO:0004872//receptor activity;GO:0005217//intracellular ligand-gated ion channel activity;GO:0043178//alcohol binding;GO:0005261//cation channel activity;GO:0005543//phospholipid binding","GO:0050909//sensory perception of taste;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006816//calcium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0051259//protein oligomerization","K04960//inositol 1,4,5-triphosphate receptor type 3","gi|6981110|ref|NP_037270.1|//inositol 1,4,5-trisphosphate receptor type 3 [Rattus norvegicus]"]
[null,25695,1139,380.878510875818,805.53651085485,-1.08061908690982,"DOWN",0.0287532350165228,"Cebpd","GO:0043231//intracellular membrane-bounded organelle","GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation","K10050//CCAAT/enhancer binding protein (C/EBP), delta","gi|6978643|ref|NP_037286.1|//CCAAT/enhancer-binding protein delta [Rattus norvegicus]"]
[null,25734,2081,162.631150701175,328.630247448137,-1.01486165283439,"DOWN",0.000955546781242619,"Hck","GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part","GO:0004713//protein tyrosine kinase activity;GO:0032559//adenyl ribonucleotide binding","GO:0006464//cellular protein modification process;GO:0050688//regulation of defense response to virus;GO:0009888//tissue development;GO:0006897//endocytosis;GO:0042742//defense response to bacterium","K08893//hemopoietic cell kinase [EC:2.7.10.2]","gi|34734058|ref|NP_037317.2|//tyrosine-protein kinase HCK [Rattus norvegicus]"]
[null,25748,1895,123.629703977953,416.111398334424,-1.75094439292671,"DOWN",0.000471121933531378,"Alas2","GO:0005759//mitochondrial matrix;GO:0044429//mitochondrial part;GO:0005743//mitochondrial inner membrane;GO:0019866//organelle inner membrane","GO:0016597//amino acid binding;GO:0016594//glycine binding;GO:0005506//iron ion binding;GO:0003870//5-aminolevulinate synthase activity;GO:0048037//cofactor binding;GO:0016749//N-succinyltransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0050662//coenzyme binding","GO:0020027//hemoglobin metabolic process;GO:0006879//cellular iron ion homeostasis;GO:0007595//lactation;GO:0007589//body fluid secretion;GO:0097421//liver regeneration;GO:0060135//maternal process involved in female pregnancy;GO:0006950//response to stress;GO:0030099//myeloid cell differentiation;GO:0022414//reproductive process;GO:0042541//hemoglobin biosynthetic process;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0010038//response to metal ion;GO:0042493//response to drug;GO:1901423//response to benzene;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0001666//response to hypoxia;GO:0030218//erythrocyte differentiation;GO:0032025//response to cobalt ion;GO:0010288//response to lead ion;GO:0006875//cellular metal ion homeostasis;GO:0070542//response to fatty acid","K00643//5-aminolevulinate synthase [EC:2.3.1.37]","gi|6978485|ref|NP_037329.1|//5-aminolevulinate synthase, erythroid-specific, mitochondrial [Rattus norvegicus]"]
[null,25756,3898,225.495441805107,57.7360605194035,1.96555369371145,"UP",{"v":3.8444004855208e-05,"d":"3.84E-05"},"Cpt1b","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0016406//carnitine O-acyltransferase activity;GO:0005488//binding","GO:0019217//regulation of fatty acid metabolic process;GO:0015908//fatty acid transport;GO:0003333//amino acid transmembrane transport","K19523//carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]","gi|6978703|ref|NP_037332.1|//carnitine O-palmitoyltransferase 1, muscle isoform [Rattus norvegicus];gi|524925840|ref|XP_005067161.1|//PREDICTED: carnitine O-palmitoyltransferase 1, muscle isoform [Mesocricetus auratus]"]
[null,26296,1619,23.0229823299135,49.1363282812489,-1.09371532806764,"DOWN",0.0321866489697527,"Tfec","GO:0043231//intracellular membrane-bounded organelle","GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated;GO:0009408//response to heat","K15591//transcription factor EC","gi|158187526|ref|NP_071774.1|//transcription factor EC [Rattus norvegicus]"]
[null,26760,1672,2784.55091633615,892.660944406812,1.64126046117568,"UP",0.00588927347587501,"Akr7a3","GO:0044444//cytoplasmic part","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0042221//response to chemical;GO:0009804//coumarin metabolic process;GO:0043387//mycotoxin catabolic process","K15303//aflatoxin B1 aldehyde reductase","gi|7106240|ref|NP_037347.1|//aflatoxin B1 aldehyde reductase member 3 [Rattus norvegicus];gi|354489569|ref|XP_003506934.1|//PREDICTED: LOW QUALITY PROTEIN: aflatoxin B1 aldehyde reductase member 3-like [Cricetulus griseus]"]
[null,29139,1674,177.694335487143,431.692967358025,-1.28060789818599,"DOWN",0.0121085696951821,"Dcn","GO:0030934//anchoring collagen complex;GO:0005589//collagen type VI trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm","GO:0044822//poly(A) RNA binding;GO:0030247//polysaccharide binding;GO:0047485//protein N-terminus binding;GO:0005518//collagen binding;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0050840//extracellular matrix binding","GO:0014706//striated muscle tissue development;GO:0001822//kidney development;GO:0032496//response to lipopolysaccharide;GO:0001890//placenta development;GO:0002237//response to molecule of bacterial origin;GO:0051901//positive regulation of mitochondrial depolarization;GO:0018149//peptide cross-linking;GO:0009611//response to wounding;GO:0009605//response to external stimulus;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0009612//response to mechanical stimulus;GO:0090141//positive regulation of mitochondrial fission;GO:0048513//animal organ development;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0046426//negative regulation of JAK-STAT cascade;GO:0042060//wound healing;GO:0007568//aging;GO:0016239//positive regulation of macroautophagy;GO:0006469//negative regulation of protein kinase activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007519//skeletal muscle tissue development;GO:0019221//cytokine-mediated signaling pathway","K04660//decorin","gi|54020664|ref|NP_077043.1|//decorin precursor [Rattus norvegicus]"]
[null,29185,1158,60.5329685820571,125.930607552245,-1.05683596531942,"DOWN",0.00551080686557602,"Cd37","GO:0031224//intrinsic component of membrane","NA","GO:0006959//humoral immune response;GO:0002377//immunoglobulin production","K06475//CD37 antigen","gi|564327918|ref|XP_006229043.1|//PREDICTED: leukocyte antigen CD37 isoform X1 [Rattus norvegicus]"]
[null,29206,1541,881.167139262355,352.114506468175,1.3233710298448,"UP",0.00302820591858015,"Ybx1-ps3","GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0044444//cytoplasmic part","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005515//protein binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048523//negative regulation of cellular process","K09276//Y-box-binding protein 1","gi|823419836|ref|XP_012420023.1|//PREDICTED: nuclease-sensitive element-binding protein 1 [Odobenus rosmarus divergens]"]
[null,29219,1176,2.69926959246681,7.48110669861475,-1.47068263261891,"DOWN",0.0371648187910128,"Snca","GO:0005856//cytoskeleton;GO:0030667//secretory granule membrane;GO:0030427//site of polarized growth;GO:0030136//clathrin-coated vesicle;GO:0033267//axon part;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","GO:0004859//phospholipase inhibitor activity;GO:0015631//tubulin binding;GO:0005506//iron ion binding;GO:0031072//heat shock protein binding;GO:0019899//enzyme binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0050543//icosatetraenoic acid binding","GO:0002694//regulation of leukocyte activation;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0042773//ATP synthesis coupled electron transport;GO:0042053//regulation of dopamine metabolic process;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0017157//regulation of exocytosis;GO:0010466//negative regulation of peptidase activity;GO:0042116//macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0010039//response to iron ion;GO:0007005//mitochondrion organization;GO:0006979//response to oxidative stress;GO:0006898//receptor-mediated endocytosis;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0030534//adult behavior;GO:0032409//regulation of transporter activity;GO:0051581//negative regulation of neurotransmitter uptake;GO:0001881//receptor recycling;GO:0030100//regulation of endocytosis;GO:0034097//response to cytokine;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0060191//regulation of lipase activity;GO:0010676//positive regulation of cellular carbohydrate metabolic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0001934//positive regulation of protein phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0019217//regulation of fatty acid metabolic process;GO:0016573//histone acetylation;GO:0032768//regulation of monooxygenase activity;GO:0051621//regulation of norepinephrine uptake;GO:0007626//locomotory behavior;GO:0019637//organophosphate metabolic process;GO:0051899//membrane depolarization","K04528//alpha-synuclein","gi|148666340|gb|EDK98756.1|//synuclein, alpha, isoform CRA_b, partial [Mus musculus]"]
[null,29225,2054,2863.42839845249,1300.51505060931,1.13866043315014,"UP",0.000733462075918597,"Ces1e","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0044432//endoplasmic reticulum part;GO:0005811//lipid particle;GO:0005829//cytosol","GO:0004806//triglyceride lipase activity;GO:0004771//sterol esterase activity;GO:0030339//fatty-acyl-ethyl-ester synthase activity","GO:0051969//regulation of transmission of nerve impulse;GO:0019626//short-chain fatty acid catabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:0006637//acyl-CoA metabolic process;GO:0046464//acylglycerol catabolic process;GO:0030855//epithelial cell differentiation;GO:0009636//response to toxic substance","K01044//carboxylesterase 1 [EC:3.1.1.1]","gi|354496802|ref|XP_003510514.1|//PREDICTED: carboxylesterase 1E [Cricetulus griseus];gi|298493214|ref|NP_113753.2|//carboxylesterase 1E precursor [Rattus norvegicus];gi|148679149|gb|EDL11096.1|//mCG145172, partial [Mus musculus]"]
[null,29230,2181,648.870011237251,291.504267154292,1.15441248834553,"UP",0.0403284573865967,"Sqle","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050660//flavin adenine dinucleotide binding;GO:0004497//monooxygenase activity;GO:0004506//squalene monooxygenase activity;GO:0050662//coenzyme binding","GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0042221//response to chemical;GO:0010033//response to organic substance;GO:0006725//cellular aromatic compound metabolic process;GO:0044237//cellular metabolic process;GO:0055114//oxidation-reduction process","K00511//squalene monooxygenase [EC:1.14.14.17]","gi|8394354|ref|NP_058832.1|//squalene monooxygenase [Rattus norvegicus]"]
[null,29260,3373,21.9908415171563,50.0680684029415,-1.18698798571477,"DOWN",0.0316123416781255,"Tlr4","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0043235//receptor complex","GO:0001530//lipopolysaccharide binding;GO:0004872//receptor activity;GO:0019900//kinase binding","GO:0032481//positive regulation of type I interferon production;GO:0032872//regulation of stress-activated MAPK cascade;GO:0070426//positive regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0010543//regulation of platelet activation;GO:0001818//negative regulation of cytokine production;GO:0001774//microglial cell activation;GO:0070391//response to lipoteichoic acid;GO:0030277//maintenance of gastrointestinal epithelium;GO:0019724//B cell mediated immunity;GO:0030888//regulation of B cell proliferation;GO:0009612//response to mechanical stimulus;GO:0033993//response to lipid;GO:0032490//detection of molecule of bacterial origin;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0006915//apoptotic process;GO:0031960//response to corticosteroid;GO:0010935//regulation of macrophage cytokine production;GO:0042742//defense response to bacterium;GO:0052166//positive regulation by symbiont of host innate immune response;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0051931//regulation of sensory perception;GO:0006941//striated muscle contraction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001934//positive regulation of protein phosphorylation;GO:0043434//response to peptide hormone;GO:0002224//toll-like receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade","K10160//toll-like receptor 4","gi|25742799|ref|NP_062051.1|//toll-like receptor 4 precursor [Rattus norvegicus]"]
[null,29292,945,93513.4448182466,37937.4746624414,1.30155015437379,"UP",0.000795309281852533,"Ftl1","GO:0044444//cytoplasmic part","GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0003824//catalytic activity","GO:0000041//transition metal ion transport;GO:0048193//Golgi vesicle transport;GO:0006875//cellular metal ion homeostasis;GO:0008152//metabolic process","K13625//ferritin light chain","gi|84000579|ref|NP_071945.3|//ferritin light chain 1 [Rattus norvegicus]"]
[null,29302,2367,128.119320452741,297.485412577093,-1.21533087534492,"DOWN",0.0139641633313037,"Itgb3","GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0032587//ruffle membrane;GO:0042470//melanosome;GO:0008305//integrin complex;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0034683//integrin alphav-beta3 complex;GO:0031527//filopodium membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0071133//alpha9-beta1 integrin-ADAM8 complex;GO:0031258//lamellipodium membrane;GO:0009986//cell surface;GO:0034679//integrin alpha9-beta1 complex;GO:0031528//microvillus membrane","GO:0031994//insulin-like growth factor I binding;GO:0019960//C-X3-C chemokine binding;GO:0001968//fibronectin binding;GO:0046983//protein dimerization activity;GO:0005172//vascular endothelial growth factor receptor binding;GO:0005178//integrin binding;GO:0003756//protein disulfide isomerase activity;GO:0004871//signal transducer activity;GO:0038132//neuregulin binding;GO:0050840//extracellular matrix binding;GO:0070051//fibrinogen binding;GO:0002020//protease binding;GO:0042802//identical protein binding;GO:0004872//receptor activity;GO:0042277//peptide binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0017134//fibroblast growth factor binding;GO:0032403//protein complex binding","GO:0010941//regulation of cell death;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0060055//angiogenesis involved in wound healing;GO:0033627//cell adhesion mediated by integrin;GO:0007566//embryo implantation;GO:0034113//heterotypic cell-cell adhesion;GO:0010594//regulation of endothelial cell migration;GO:0009611//response to wounding;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0048146//positive regulation of fibroblast proliferation;GO:0010761//fibroblast migration;GO:0032846//positive regulation of homeostatic process;GO:0048858//cell projection morphogenesis;GO:0009314//response to radiation;GO:0010742//macrophage derived foam cell differentiation;GO:0033690//positive regulation of osteoblast proliferation;GO:0046718//viral entry into host cell;GO:0001954//positive regulation of cell-matrix adhesion;GO:0007044//cell-substrate junction assembly;GO:0006869//lipid transport;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0032369//negative regulation of lipid transport;GO:0016049//cell growth;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0061097//regulation of protein tyrosine kinase activity;GO:0007229//integrin-mediated signaling pathway;GO:0006935//chemotaxis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0051704//multi-organism process;GO:0014823//response to activity;GO:0030030//cell projection organization;GO:0032269//negative regulation of cellular protein metabolic process;GO:0045780//positive regulation of bone resorption;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010871//negative regulation of receptor biosynthetic process;GO:0060548//negative regulation of cell death;GO:0070527//platelet aggregation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010763//positive regulation of fibroblast migration;GO:0034329//cell junction assembly;GO:0035690//cellular response to drug;GO:0071260//cellular response to mechanical stimulus;GO:0014909//smooth muscle cell migration;GO:0010595//positive regulation of endothelial cell migration;GO:0045672//positive regulation of osteoclast differentiation;GO:0032956//regulation of actin cytoskeleton organization;GO:1900731//positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0034109//homotypic cell-cell adhesion;GO:0007599//hemostasis;GO:2000406//positive regulation of T cell migration;GO:0001935//endothelial cell proliferation;GO:0045715//negative regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0042493//response to drug;GO:0009612//response to mechanical stimulus;GO:0032147//activation of protein kinase activity;GO:0010628//positive regulation of gene expression;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0050748//negative regulation of lipoprotein metabolic process;GO:0010888//negative regulation of lipid storage;GO:0050919//negative chemotaxis;GO:1903053//regulation of extracellular matrix organization;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0001934//positive regulation of protein phosphorylation;GO:0048333//mesodermal cell differentiation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0010883//regulation of lipid storage;GO:0031589//cell-substrate adhesion;GO:0002684//positive regulation of immune system process;GO:0001775//cell activation;GO:0006875//cellular metal ion homeostasis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation;GO:0006887//exocytosis","K06493//integrin beta 3","gi|24308466|ref|NP_714942.1|//integrin beta-3 precursor [Rattus norvegicus]"]
[null,29362,4158,306.270182622782,737.7522109971,-1.26833142122199,"DOWN",{"v":3.93681359984201e-05,"d":"3.94E-05"},"Tef","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus","GO:0043566//structure-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048511//rhythmic process","K09058//thyrotrophic embryonic factor","gi|76362828|ref|NP_062067.2|//thyrotroph embryonic factor [Rattus norvegicus];gi|149065828|gb|EDM15701.1|//thyrotroph embryonic factor, isoform CRA_a [Rattus norvegicus];gi|564361160|ref|XP_006242130.1|//PREDICTED: thyrotroph embryonic factor isoform X1 [Rattus norvegicus]"]
[null,29372,2518,33.2434586820349,81.8009727301891,-1.29904750964632,"DOWN",0.0109162021321761,"Rasa3","GO:0044424//intracellular part;GO:0009898//cytoplasmic side of plasma membrane","GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0008047//enzyme activator activity","GO:0006816//calcium ion transport","K12380//Ras GTPase-activating protein 3","gi|115432015|ref|NP_113762.1|//ras GTPase-activating protein 3 [Rattus norvegicus]"]
[null,29393,5843,53.755709028449,373.129241052591,-2.79518553761127,"DOWN",{"v":3.07117175635702e-07,"d":"3.07E-07"},"Col1a1","GO:0005583//fibrillar collagen trimer;GO:0044424//intracellular part","GO:0005515//protein binding;GO:0005198//structural molecule activity","GO:0051716//cellular response to stimulus;GO:0007600//sensory perception;GO:0007162//negative regulation of cell adhesion;GO:0051216//cartilage development;GO:0001503//ossification;GO:0000302//response to reactive oxygen species;GO:0048522//positive regulation of cellular process;GO:0001944//vasculature development;GO:0006810//transport;GO:0051291//protein heterooligomerization;GO:0030154//cell differentiation;GO:0007154//cell communication;GO:0032526//response to retinoic acid;GO:0060343//trabecula formation;GO:0048545//response to steroid hormone;GO:0008544//epidermis development;GO:0070848//response to growth factor;GO:0008104//protein localization","K06236//collagen, type I, alpha","gi|149053909|gb|EDM05726.1|//procollagen, type 1, alpha 1, isoform CRA_a [Rattus norvegicus]"]
[null,29465,2812,19.6895340710277,89.5070598880421,-2.1845725077246,"DOWN",{"v":2.60665828743889e-05,"d":"2.61E-05"},"Trpv2","GO:0031224//intrinsic component of membrane;GO:0048770//pigment granule","GO:0005488//binding;GO:0005261//cation channel activity","GO:0006950//response to stress;GO:0009628//response to abiotic stimulus;GO:0070838//divalent metal ion transport","K04971//transient receptor potential cation channel subfamily V member 2","gi|78187981|ref|NP_058903.2|//transient receptor potential cation channel subfamily V member 2 [Rattus norvegicus]"]
[null,29469,1881,8118.11748128201,28313.3154241192,-1.80226357215593,"DOWN",{"v":8.31431678699428e-07,"d":"8.31E-07"},"Lbp","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part","GO:0005515//protein binding","GO:0042108//positive regulation of cytokine biosynthetic process;GO:0042742//defense response to bacterium;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0002699//positive regulation of immune effector process;GO:0002523//leukocyte migration involved in inflammatory response;GO:0010876//lipid localization;GO:0015774//polysaccharide transport;GO:0001818//negative regulation of cytokine production;GO:0070391//response to lipoteichoic acid;GO:0002696//positive regulation of leukocyte activation;GO:0044126//regulation of growth of symbiont in host;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002275//myeloid cell activation involved in immune response;GO:0002526//acute inflammatory response","K05399//lipopolysaccharide-binding protein","gi|139948891|ref|NP_058904.2|//lipopolysaccharide-binding protein precursor [Rattus norvegicus]"]
[null,29480,2919,50.899745927547,206.427282400879,-2.01990329668818,"DOWN",0.00147144405012541,"Rgs4","GO:0016020//membrane;GO:0044444//cytoplasmic part","GO:0005515//protein binding;GO:0060089//molecular transducer activity;GO:0008047//enzyme activator activity","GO:0007186//G-protein coupled receptor signaling pathway","K16449//regulator of G-protein signaling","gi|829785807|ref|XP_012624111.1|//PREDICTED: regulator of G-protein signaling 4 isoform X1 [Microcebus murinus]"]
[null,29515,4385,430.557119527523,187.053603715203,1.20275288368145,"UP",0.0210238969444374,"Atn1","GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0005654//nucleoplasm;GO:0030054//cell junction;GO:0016363//nuclear matrix;GO:0048471//perinuclear region of cytoplasm","GO:0050827//toxin receptor binding;GO:0019904//protein domain specific binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003712//transcription cofactor activity;GO:0008432//JUN kinase binding;GO:0005102//receptor binding;GO:0019901//protein kinase binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051402//neuron apoptotic process;GO:0009404//toxin metabolic process;GO:0045664//regulation of neuron differentiation;GO:0050767//regulation of neurogenesis;GO:0019748//secondary metabolic process","K05626//atrophin-1 (dentatorubral-pallidoluysian atrophy protein)","gi|158517923|ref|NP_058924.2|//atrophin-1 [Rattus norvegicus];gi|1706520|sp|P54258.1|ATN1_RAT//RecName: Full=Atrophin-1; AltName: Full=Dentatorubral-pallidoluysian atrophy protein homolog"]
[null,29543,1656,120.359139857757,349.185815596389,-1.53664925426655,"DOWN",{"v":5.40082329741471e-06,"d":"5.40E-06"},"Timp2","GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044297//cell body;GO:0030427//site of polarized growth;GO:0005578//proteinaceous extracellular matrix","GO:0043169//cation binding;GO:0004866//endopeptidase inhibitor activity;GO:0005102//receptor binding","GO:0010466//negative regulation of peptidase activity;GO:0007346//regulation of mitotic cell cycle;GO:0048232//male gamete generation;GO:0046058//cAMP metabolic process;GO:0031281//positive regulation of cyclase activity;GO:0046578//regulation of Ras protein signal transduction;GO:0008283//cell proliferation;GO:0030162//regulation of proteolysis;GO:0010033//response to organic substance;GO:0045597//positive regulation of cell differentiation;GO:0032486//Rap protein signal transduction;GO:0050767//regulation of neurogenesis","K16866//metalloproteinase inhibitor 3","gi|267133|sp|P25785.2|TIMP2_MOUSE//RecName: Full=Metalloproteinase inhibitor 2; AltName: Full=Tissue inhibitor of metalloproteinases 2; Short=TIMP-2; Flags: Precursor"]
[null,29569,1547,92.1749751203619,545.031895153852,-2.56389363155241,"DOWN",{"v":9.36720792756388e-07,"d":"9.37E-07"},"Pcolce","GO:0044421//extracellular region part","GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008047//enzyme activator activity","GO:0019538//protein metabolic process;GO:0051345//positive regulation of hydrolase activity","K14616//cubilin","gi|9506953|ref|NP_062110.1|//procollagen C-endopeptidase enhancer 1 precursor [Rattus norvegicus]"]
[null,29583,2857,274.538110164241,574.634100925533,-1.06563717863596,"DOWN",0.000502739753742018,"Pecam1","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0030667//secretory granule membrane;GO:0005615//extracellular space;GO:0044459//plasma membrane part;GO:0009897//external side of plasma membrane;GO:0030054//cell junction;GO:0030485//smooth muscle contractile fiber;GO:0043292//contractile fiber;GO:0031224//intrinsic component of membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0005515//protein binding;GO:0005488//binding","GO:0034097//response to cytokine;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0010033//response to organic substance;GO:0006897//endocytosis;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0072011//glomerular endothelium development;GO:0006909//phagocytosis;GO:0009611//response to wounding;GO:0050904//diapedesis;GO:0001886//endothelial cell morphogenesis;GO:0001525//angiogenesis;GO:0043542//endothelial cell migration;GO:0050900//leukocyte migration;GO:0042060//wound healing;GO:0090673//endothelial cell-matrix adhesion;GO:0007266//Rho protein signal transduction;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0030837//negative regulation of actin filament polymerization;GO:0034260//negative regulation of GTPase activity;GO:0007265//Ras protein signal transduction;GO:0002687//positive regulation of leukocyte migration","K06471//platelet/endothelial cell adhesion molecule","gi|149054589|gb|EDM06406.1|//platelet/endothelial cell adhesion molecule, isoform CRA_c [Rattus norvegicus];gi|75832033|ref|NP_113779.1|//platelet endothelial cell adhesion molecule precursor [Rattus norvegicus];gi|149054588|gb|EDM06405.1|//platelet/endothelial cell adhesion molecule, isoform CRA_b [Rattus norvegicus];gi|149054587|gb|EDM06404.1|//platelet/endothelial cell adhesion molecule, isoform CRA_a [Rattus norvegicus]"]
[null,29624,965,32.6754621067568,86.429332745789,-1.40331338411016,"DOWN",0.00118048899081875,"Alox5ap","GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031090//organelle membrane","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity;GO:0046983//protein dimerization activity;GO:0050543//icosatetraenoic acid binding","GO:0006691//leukotriene metabolic process;GO:0051592//response to calcium ion;GO:0019222//regulation of metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0051260//protein homooligomerization;GO:0002538//arachidonic acid metabolite production involved in inflammatory response","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|8392897|ref|NP_058956.1|//arachidonate 5-lipoxygenase-activating protein [Rattus norvegicus]"]
[null,29637,3389,9163.80927682695,2531.43268834683,1.85599330963766,"UP",0.000191997093014425,"Hmgcs1","GO:0044444//cytoplasmic part","GO:0042802//identical protein binding;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer","GO:0070723//response to cholesterol;GO:0014070//response to organic cyclic compound;GO:0008203//cholesterol metabolic process;GO:0006720//isoprenoid metabolic process;GO:0007417//central nervous system development;GO:0032354//response to follicle-stimulating hormone;GO:0008406//gonad development;GO:0009642//response to light intensity;GO:0010038//response to metal ion;GO:0033273//response to vitamin","K01641//hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]","gi|537235061|gb|ERE85068.1|//hydroxymethylglutaryl-CoA synthase, cytoplasmic-like protein [Cricetulus griseus];gi|440906773|gb|ELR57001.1|//Hydroxymethylglutaryl-CoA synthase, cytoplasmic, partial [Bos mutus];gi|674066774|ref|XP_008840337.1|//PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic [Nannospalax galili];gi|149059420|gb|EDM10427.1|//rCG44679, isoform CRA_b [Rattus norvegicus]"]
[null,29657,3128,364.333545341395,141.107142555583,1.36846881862774,"UP",0.000532260512665605,"Arntl","GO:0043231//intracellular membrane-bounded organelle;GO:0016605//PML body;GO:0043234//protein complex;GO:0033391//chromatoid body;GO:0005667//transcription factor complex","GO:0070888//E-box binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0031072//heat shock protein binding;GO:0046982//protein heterodimerization activity;GO:0070491//repressing transcription factor binding;GO:0005102//receptor binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0051879//Hsp90 protein binding;GO:0043425//bHLH transcription factor binding;GO:0004871//signal transducer activity","GO:0032007//negative regulation of TOR signaling;GO:0000060//protein import into nucleus, translocation;GO:0090403//oxidative stress-induced premature senescence;GO:0007283//spermatogenesis;GO:0009894//regulation of catabolic process;GO:0050796//regulation of insulin secretion;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0023052//signaling;GO:0032922//circadian regulation of gene expression;GO:0007623//circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042634//regulation of hair cycle;GO:0045599//negative regulation of fat cell differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0051775//response to redox state;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:2000074//regulation of type B pancreatic cell development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042176//regulation of protein catabolic process;GO:0006606//protein import into nucleus;GO:2001016//positive regulation of skeletal muscle cell differentiation;GO:0042753//positive regulation of circadian rhythm;GO:0051726//regulation of cell cycle;GO:2000772//regulation of cellular senescence;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0050767//regulation of neurogenesis;GO:0060137//maternal process involved in parturition","K02296//aryl hydrocarbon receptor nuclear translocator-like protein 1","gi|817283650|ref|XP_012312038.1|//PREDICTED: aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X3 [Aotus nancymaae];gi|537206173|gb|ERE79929.1|//aryl hydrocarbon receptor nuclear translocator-like protein 1 [Cricetulus griseus];gi|71896600|ref|NP_077338.2|//aryl hydrocarbon receptor nuclear translocator-like protein 1 [Rattus norvegicus]"]
[null,29692,783,29.6963409940346,87.3991432536974,-1.55733395580885,"DOWN",0.0167344850057851,"Pla2g2a","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0016023//null;GO:0048471//perinuclear region of cytoplasm;GO:0030141//secretory granule;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0005509//calcium ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0004623//phospholipase A2 activity;GO:0005543//phospholipid binding","GO:0016042//lipid catabolic process;GO:0035019//somatic stem cell population maintenance;GO:0042130//negative regulation of T cell proliferation;GO:0006650//glycerophospholipid metabolic process;GO:0019827//stem cell population maintenance;GO:0006644//phospholipid metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008285//negative regulation of cell proliferation","K01047//secretory phospholipase A2 [EC:3.1.1.4]","gi|291621686|ref|NP_113786.3|//phospholipase A2, membrane associated precursor [Rattus norvegicus]"]
[null,29715,6161,38.6028873707709,104.515643638314,-1.43693823187698,"DOWN",0.0136127306593686,"Slc8a1","GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0043231//intracellular membrane-bounded organelle;GO:0044459//plasma membrane part;GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0042383//sarcolemma","GO:0015291//secondary active transmembrane transporter activity;GO:0005515//protein binding;GO:0015081//sodium ion transmembrane transporter activity","GO:0035725//sodium ion transmembrane transport;GO:0003012//muscle system process;GO:0009746//response to hexose;GO:0051591//response to cAMP;GO:0006816//calcium ion transport;GO:0000302//response to reactive oxygen species;GO:0001775//cell activation;GO:0010959//regulation of metal ion transport;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0008016//regulation of heart contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007599//hemostasis;GO:0006814//sodium ion transport;GO:0070838//divalent metal ion transport","K05849//solute carrier family 8 (sodium/calcium exchanger)","gi|398650648|ref|NP_001257708.1|//sodium/calcium exchanger 1 isoform 9 precursor [Rattus norvegicus] ;gi|398650642|ref|NP_001257705.1|//sodium/calcium exchanger 1 isoform 6 precursor [Rattus norvegicus] ;gi|398650638|ref|NP_001257703.1|//sodium/calcium exchanger 1 isoform 4 precursor [Rattus norvegicus];gi|398650640|ref|NP_001257704.1|//sodium/calcium exchanger 1 isoform 5 precursor [Rattus norvegicus];gi|398650636|ref|NP_001257702.1|//sodium/calcium exchanger 1 isoform 3 precursor [Rattus norvegicus];gi|398650632|ref|NP_001257701.1|//sodium/calcium exchanger 1 isoform 2 precursor [Rattus norvegicus];gi|398650644|ref|NP_001257706.1|//sodium/calcium exchanger 1 isoform 7 precursor [Rattus norvegicus] ;gi|398650622|ref|NP_062141.3|//sodium/calcium exchanger 1 isoform 1 precursor [Rattus norvegicus];gi|398650646|ref|NP_001257707.1|//sodium/calcium exchanger 1 isoform 8 precursor [Rattus norvegicus] "]
[null,29740,989,11309.2482932308,4155.36466017434,1.44445604549261,"UP",0.0118500165194362,"Eci1","GO:0044429//mitochondrial part;GO:0019866//organelle inner membrane","GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds","GO:0009062//fatty acid catabolic process","K13238//3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8]","gi|162287040|ref|NP_059002.2|//enoyl-CoA delta isomerase 1, mitochondrial precursor [Rattus norvegicus]"]
[null,50567,1857,4416.03007190065,1755.75887407109,1.33065526953683,"UP",0.00170662759237151,"Slc3a2","GO:0031224//intrinsic component of membrane;GO:0044459//plasma membrane part;GO:0048770//pigment granule","GO:0043167//ion binding;GO:0015171//amino acid transmembrane transporter activity","GO:0015801//aromatic amino acid transport;GO:0044238//primary metabolic process;GO:0015820//leucine transport","K06519//solute carrier family 3, member 2","gi|402743472|ref|NP_062156.2|//4F2 cell-surface antigen heavy chain isoform 1 [Rattus norvegicus]"]
[null,50654,1739,743.594387354854,1783.90729096661,-1.2624528548942,"DOWN",{"v":6.13177118124999e-07,"d":"6.13E-07"},"Ctss","GO:0000323//lytic vacuole","GO:0004175//endopeptidase activity;GO:0005488//binding","GO:0019538//protein metabolic process","K01368//cathepsin S [EC:3.4.22.27]","gi|537259880|gb|ERE89868.1|//cathepsin K [Cricetulus griseus];gi|8393221|ref|NP_059016.1|//cathepsin S preproprotein [Rattus norvegicus]"]
[null,50662,2613,21.2165926660291,122.931127499502,-2.53458538145566,"DOWN",{"v":2.07867802158593e-09,"d":"2.08E-09"},"Runx1","GO:0031981//nuclear lumen;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005604//basement membrane","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0070491//repressing transcription factor binding;GO:0042803//protein homodimerization activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046872//metal ion binding;GO:0032559//adenyl ribonucleotide binding;GO:0005509//calcium ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:1990841//promoter-specific chromatin binding;GO:0008134//transcription factor binding;GO:0001047//core promoter binding","GO:1903431//positive regulation of cell maturation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0043009//chordate embryonic development;GO:0030728//ovulation;GO:0048666//neuron development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030853//negative regulation of granulocyte differentiation;GO:0002667//regulation of T cell anergy;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0002318//myeloid progenitor cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0048468//cell development;GO:0033189//response to vitamin A;GO:0008285//negative regulation of cell proliferation;GO:0032729//positive regulation of interferon-gamma production;GO:0007610//behavior;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000872//positive regulation of progesterone secretion;GO:0002062//chondrocyte differentiation;GO:0031069//hair follicle morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048663//neuron fate commitment;GO:0009966//regulation of signal transduction;GO:0007399//nervous system development;GO:0001503//ossification;GO:0032743//positive regulation of interleukin-2 production;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0071336//regulation of hair follicle cell proliferation;GO:0035162//embryonic hemopoiesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0060216//definitive hemopoiesis;GO:0001889//liver development;GO:0030854//positive regulation of granulocyte differentiation;GO:0001701//in utero embryonic development;GO:0007417//central nervous system development;GO:0032526//response to retinoic acid;GO:0048266//behavioral response to pain;GO:0045765//regulation of angiogenesis","K08367//runt-related transcription factor 1;K09278//runt-related transcription factor 2","gi|149059888|gb|EDM10771.1|//runt related transcription factor 1, isoform CRA_b [Rattus norvegicus];gi|8392900|ref|NP_059021.1|//runt-related transcription factor 1 [Rattus norvegicus]"]
[null,50671,9737,1537.37582512441,674.686503038092,1.18818068128576,"UP",0.00447543294517415,"Fasn","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0042587//glycogen granule;GO:0042470//melanosome;GO:0005913//cell-cell adherens junction;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0048770//pigment granule;GO:0005886//plasma membrane","GO:0031177//phosphopantetheine binding;GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0004313//[acyl-carrier-protein] S-acetyltransferase activity;GO:0019842//vitamin binding;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0047451//3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity;GO:0004319//enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity;GO:0070402//NADPH binding;GO:0022892//substrate-specific transporter activity;GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0008144//drug binding;GO:0047117//enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity;GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0102132//3-oxo-pimeloyl-[acp] methyl ester reductase activity;GO:0016297//acyl-[acyl-carrier-protein] hydrolase activity;GO:0004317//3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0044822//poly(A) RNA binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042803//protein homodimerization activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0050661//NADP binding;GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity","GO:0001649//osteoblast differentiation;GO:0006641//triglyceride metabolic process;GO:0055114//oxidation-reduction process;GO:0006732//coenzyme metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006631//fatty acid metabolic process;GO:0071353//cellular response to interleukin-4;GO:0006633//fatty acid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0051234//establishment of localization;GO:0030879//mammary gland development","K00665//fatty acid synthase, animal type [EC:2.3.1.85]","gi|2506136|sp|P12785.3|FAS_RAT//RecName: Full=Fatty acid synthase; Includes: RecName: Full=[Acyl-carrier-protein] S-acetyltransferase; Includes: RecName: Full=[Acyl-carrier-protein] S-malonyltransferase; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase; Includes: RecName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Includes: RecName: Full=Enoyl-[acyl-carrier-protein] reductase; Includes: RecName: Full=Oleoyl-[acyl-carrier-protein] hydrolase;gi|8394158|ref|NP_059028.1|//fatty acid synthase [Rattus norvegicus];gi|148702862|gb|EDL34809.1|//fatty acid synthase, isoform CRA_b [Mus musculus];gi|56133|emb|CAA31780.1|//unnamed protein product [Rattus norvegicus]"]
[null,50672,4082,158.642304124956,404.761560428262,-1.35129474947625,"DOWN",0.000728435361671522,"Ednrb","GO:0031965//nuclear membrane;GO:0045121//membrane raft;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031702//type 1 angiotensin receptor binding;GO:0017046//peptide hormone binding;GO:0004962//endothelin receptor activity;GO:0031701//angiotensin receptor binding","GO:0008217//regulation of blood pressure;GO:0014043//negative regulation of neuron maturation;GO:0042127//regulation of cell proliferation;GO:0006885//regulation of pH;GO:0071222//cellular response to lipopolysaccharide;GO:0050880//regulation of blood vessel size;GO:0007494//midgut development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033555//multicellular organismal response to stress;GO:0050931//pigment cell differentiation;GO:0048246//macrophage chemotaxis;GO:0042044//fluid transport;GO:0060406//positive regulation of penile erection;GO:0001755//neural crest cell migration;GO:0001660//fever generation;GO:0051240//positive regulation of multicellular organismal process;GO:0043066//negative regulation of apoptotic process;GO:0086100//endothelin receptor signaling pathway;GO:0050678//regulation of epithelial cell proliferation;GO:0006915//apoptotic process;GO:0051930//regulation of sensory perception of pain;GO:0007422//peripheral nervous system development;GO:0031280//negative regulation of cyclase activity;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0055067//monovalent inorganic cation homeostasis;GO:0014070//response to organic cyclic compound;GO:0032496//response to lipopolysaccharide;GO:0035645//enteric smooth muscle cell differentiation;GO:0051931//regulation of sensory perception;GO:0001932//regulation of protein phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014826//vein smooth muscle contraction;GO:0042045//epithelial fluid transport;GO:0019934//cGMP-mediated signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0048265//response to pain;GO:0031620//regulation of fever generation;GO:0014041//regulation of neuron maturation;GO:0030318//melanocyte differentiation;GO:0042311//vasodilation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007497//posterior midgut development;GO:0030595//leukocyte chemotaxis;GO:0032269//negative regulation of cellular protein metabolic process;GO:0001667//ameboidal-type cell migration;GO:0007568//aging;GO:0048484//enteric nervous system development;GO:0035815//positive regulation of renal sodium excretion;GO:0014821//phasic smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035810//positive regulation of urine volume;GO:0008284//positive regulation of cell proliferation","K04198//endothelin receptor type B","gi|148668175|gb|EDL00505.1|//endothelin receptor type B, isoform CRA_b, partial [Mus musculus]"]
[null,50677,2820,46.140761762665,119.918724855762,-1.37794322016196,"DOWN",0.000878241628891555,"Ptpro","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0043197//dendritic spine","GO:0004871//signal transducer activity;GO:0017147//Wnt-protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0042803//protein homodimerization activity","GO:0030032//lamellipodium assembly;GO:0003105//negative regulation of glomerular filtration;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0048731//system development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006464//cellular protein modification process;GO:0036060//slit diaphragm assembly;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0002548//monocyte chemotaxis;GO:0007411//axon guidance","K18035//receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48]","gi|958819396|ref|XP_014689678.1|//PREDICTED: receptor-type tyrosine-protein phosphatase O [Equus asinus];gi|8394227|ref|NP_059032.1|//receptor-type tyrosine-protein phosphatase O precursor [Rattus norvegicus]"]
[null,54231,1459,411.904241226941,154.298514853009,1.41658480537119,"UP",0.000854504209437215,"Car2","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part;GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part;GO:0043005//neuron projection","GO:0016836//hydro-lyase activity;GO:0046914//transition metal ion binding;GO:0048037//cofactor binding","GO:0015669//gas transport;GO:0048729//tissue morphogenesis;GO:0006885//regulation of pH;GO:0009628//response to abiotic stimulus;GO:0032846//positive regulation of homeostatic process;GO:0048545//response to steroid hormone;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0044237//cellular metabolic process;GO:0010038//response to metal ion;GO:0042476//odontogenesis","K18245//carbonic anhydrase 2 [EC:4.2.1.1]","gi|9506445|ref|NP_062164.1|//carbonic anhydrase 2 [Rattus norvegicus]"]
[null,54232,1952,699.862823014596,259.594930379426,1.43080996428717,"UP",0.0215226609880816,"Car3","GO:0044424//intracellular part;GO:0005829//cytosol","GO:0016836//hydro-lyase activity;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity;GO:0016791//phosphatase activity;GO:0016151//nickel cation binding","GO:0006979//response to oxidative stress;GO:0006950//response to stress;GO:0006730//one-carbon metabolic process;GO:0044237//cellular metabolic process;GO:0016311//dephosphorylation;GO:0045471//response to ethanol","K01672//carbonic anhydrase [EC:4.2.1.1]","gi|31377484|ref|NP_062165.2|//carbonic anhydrase 3 [Rattus norvegicus]"]
[null,54242,1441,2.36787200577899,7.16901468078591,-1.59818374770197,"DOWN",0.0217412967650252,"Cpa3","GO:0016023//null","GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity","GO:0019538//protein metabolic process","K08780//carboxypeptidase A3 [EC:3.4.17.1]","gi|213512704|ref|NP_062173.1|//mast cell carboxypeptidase A precursor [Rattus norvegicus]"]
[null,54249,846,385.048484217515,820.616529702315,-1.09166809744072,"DOWN",0.000443874622887178,"Cfd","GO:0044421//extracellular region part","GO:0004175//endopeptidase activity","GO:0006956//complement activation;GO:0007166//cell surface receptor signaling pathway","K01334//component factor D [EC:3.4.21.46]","gi|117647198|ref|NP_001071110.1|//complement factor D precursor [Rattus norvegicus]"]
[null,54251,5514,245.705638557971,562.016486152317,-1.19368148532024,"DOWN",0.000901574836954969,"Flt1","GO:0031981//nuclear lumen;GO:0005768//endosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0043235//receptor complex","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0036326//VEGF-A-activated receptor activity;GO:0019838//growth factor binding;GO:0004716//signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0036332//placental growth factor-activated receptor activity;GO:0036327//VEGF-B-activated receptor activity;GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0060252//positive regulation of glial cell proliferation;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0097421//liver regeneration;GO:0048869//cellular developmental process;GO:0045471//response to ethanol;GO:1901534//positive regulation of hematopoietic progenitor cell differentiation;GO:0032355//response to estradiol;GO:0045766//positive regulation of angiogenesis;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0007565//female pregnancy;GO:0001525//angiogenesis;GO:0036323//vascular endothelial growth factor receptor-1 signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:1903671//negative regulation of sprouting angiogenesis;GO:0046777//protein autophosphorylation;GO:0010863//positive regulation of phospholipase C activity;GO:0030522//intracellular receptor signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0048598//embryonic morphogenesis;GO:1904046//negative regulation of vascular endothelial growth factor production;GO:0071456//cellular response to hypoxia;GO:0006950//response to stress;GO:0006937//regulation of muscle contraction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002548//monocyte chemotaxis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0000165//MAPK cascade;GO:0043406//positive regulation of MAP kinase activity;GO:0014823//response to activity;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006940//regulation of smooth muscle contraction;GO:0007568//aging;GO:0006464//cellular protein modification process;GO:0009967//positive regulation of signal transduction;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0008284//positive regulation of cell proliferation","K05096//FMS-like tyrosine kinase 1 [EC:2.7.10.1]","gi|827835089|ref|NP_001296310.1|//vascular endothelial growth factor receptor 1 isoform 2 precursor [Rattus norvegicus];gi|828178219|ref|NP_062179.2|//vascular endothelial growth factor receptor 1 isoform 1 precursor [Rattus norvegicus]"]
[null,54260,3951,50.6519565602567,111.789478233003,-1.14209450332063,"DOWN",0.0304170257872474,"Itpkb","NA","GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding;GO:0051766//inositol trisphosphate kinase activity","GO:0046578//regulation of Ras protein signal transduction;GO:0045582//positive regulation of T cell differentiation;GO:0043368//positive T cell selection;GO:0006796//phosphate-containing compound metabolic process","K00911//1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]","gi|164565364|ref|NP_062185.2|//inositol-trisphosphate 3-kinase B [Rattus norvegicus]"]
[null,54292,5121,68.5952255448435,192.827862168931,-1.49113345651452,"DOWN",0.00105962240270729,"Rgs12","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0030054//cell junction;GO:0097440//apical dendrite;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0043234//protein complex;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0001965//G-protein alpha-subunit binding;GO:0004871//signal transducer activity;GO:0060589//nucleoside-triphosphatase regulator activity;GO:0008047//enzyme activator activity;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity","K16449//regulator of G-protein signaling","gi|9507043|ref|NP_062212.1|//regulator of G-protein signaling 12 [Rattus norvegicus];gi|149047407|gb|EDM00077.1|//regulator of G-protein signaling 12, isoform CRA_c [Rattus norvegicus]"]
[null,54294,3408,547.89220280497,1196.61107802435,-1.1269903468577,"DOWN",0.0331241736649182,"Rgs5","GO:0016020//membrane;GO:0044424//intracellular part","GO:0060089//molecular transducer activity;GO:0008047//enzyme activator activity","GO:0043087//regulation of GTPase activity;GO:0007166//cell surface receptor signaling pathway","K16449//regulator of G-protein signaling","gi|9507045|ref|NP_062214.1|//regulator of G-protein signaling 5 [Rattus norvegicus];gi|524937811|ref|XP_005071479.1|//PREDICTED: regulator of G-protein signaling 5 [Mesocricetus auratus]"]
[null,54349,7147,14556.2230083805,6984.72429216468,1.05936098483921,"UP",0.00489812954703442,"Aox1","GO:0044444//cytoplasmic part","GO:0016623//oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor;GO:0000166//nucleotide binding;GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0050662//coenzyme binding","GO:0044237//cellular metabolic process","K00157//aldehyde oxidase [EC:1.2.3.1]","gi|625197425|ref|XP_007640844.1|//PREDICTED: aldehyde oxidase 1 isoform X1 [Cricetulus griseus];gi|20072148|gb|AAH26132.1|//Aldehyde oxidase 1 [Mus musculus];gi|32996707|ref|NP_062236.2|//aldehyde oxidase 1 [Rattus norvegicus]"]
[null,54404,3024,52870.9391823747,144913.572762756,-1.45464586597878,"DOWN",{"v":7.90332039013389e-09,"d":"7.90E-09"},"Itih4","GO:0016020//membrane;GO:0044424//intracellular part","GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity","GO:0030203//glycosaminoglycan metabolic process","K19014//inter-alpha-trypsin inhibitor heavy chain H1;K19015//inter-alpha-trypsin inhibitor heavy chain H2","gi|126722991|ref|NP_062242.2|//inter-alpha-trypsin inhibitor heavy chain H4 precursor [Rattus norvegicus];gi|589937616|ref|XP_006981565.1|//PREDICTED: inter alpha-trypsin inhibitor, heavy chain 4-like [Peromyscus maniculatus bairdii]"]
[null,54702,2825,47.8633182187439,136.329261468844,-1.51010292973372,"DOWN",0.0169238764052191,"Egln3","GO:0043231//intracellular membrane-bounded organelle","GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019842//vitamin binding;GO:0046914//transition metal ion binding","GO:0008152//metabolic process;GO:0008283//cell proliferation;GO:0012501//programmed cell death;GO:0006950//response to stress","K09592//hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]","gi|9507123|ref|NP_062244.1|//egl nine homolog 3 [Rattus norvegicus]"]
[null,56761,7319,22.3140710304254,52.2904166176628,-1.22859281853575,"DOWN",0.0499090522024822,"Notch3","GO:0031981//nuclear lumen;GO:0044432//endoplasmic reticulum part;GO:0016021//integral component of membrane;GO:0044431//Golgi apparatus part","GO:0005488//binding","GO:0045165//cell fate commitment;GO:0044267//cellular protein metabolic process;GO:0045596//negative regulation of cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007420//brain development","K02599//Notch 1","gi|9966775|ref|NP_064472.2|//neurogenic locus notch homolog protein 3 precursor [Rattus norvegicus]"]
[null,58835,1803,384.68739384439,113.744133455188,1.75789441567203,"UP",0.0051860052739743,"Phgdh","NA","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding","GO:0010001//glial cell differentiation;GO:0009064//glutamine family amino acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0030030//cell projection organization;GO:0007417//central nervous system development;GO:0006563//L-serine metabolic process;GO:0009066//aspartate family amino acid metabolic process;GO:0010467//gene expression;GO:0007049//cell cycle","K00058//D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]","gi|13928850|ref|NP_113808.1|//D-3-phosphoglycerate dehydrogenase [Rattus norvegicus]"]
[null,58917,1610,131374.631512952,344101.215539036,-1.38914627077047,"DOWN",{"v":7.35941126246504e-06,"d":"7.36E-06"},"Hpx","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005623//cell","GO:0015232//heme transporter activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0005506//iron ion binding","GO:0020027//hemoglobin metabolic process;GO:0006879//cellular iron ion homeostasis;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0060255//regulation of macromolecule metabolic process;GO:0002639//positive regulation of immunoglobulin production;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0060330//regulation of response to interferon-gamma;GO:0042168//heme metabolic process;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0051234//establishment of localization;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006778//porphyrin-containing compound metabolic process;GO:0002377//immunoglobulin production;GO:0015886//heme transport;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin","K18977//hemopexin [EC:3.2.1.35]","gi|16758014|ref|NP_445770.1|//hemopexin precursor [Rattus norvegicus];gi|122065203|sp|P20059.3|HEMO_RAT//RecName: Full=Hemopexin; Flags: Precursor;gi|149068486|gb|EDM18038.1|//hemopexin, isoform CRA_e [Rattus norvegicus]"]
[null,58949,3396,92.0234868324927,197.655553046665,-1.10291446033004,"DOWN",0.00315081702604978,"Ptafr","GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0005654//nucleoplasm;GO:0005887//integral component of plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0001530//lipopolysaccharide binding;GO:0051019//mitogen-activated protein kinase binding;GO:0004992//platelet activating factor receptor activity;GO:0001875//lipopolysaccharide receptor activity","GO:1904317//cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine;GO:0007166//cell surface receptor signaling pathway;GO:0045776//negative regulation of blood pressure;GO:0032760//positive regulation of tumor necrosis factor production;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0048017//inositol lipid-mediated signaling;GO:0045909//positive regulation of vasodilation;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0010863//positive regulation of phospholipase C activity;GO:0048015//phosphatidylinositol-mediated signaling;GO:0071258//cellular response to gravity;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway;GO:0009609//response to symbiotic bacterium;GO:1902943//positive regulation of voltage-gated chloride channel activity;GO:0045727//positive regulation of translation;GO:0002237//response to molecule of bacterial origin;GO:0032959//inositol trisphosphate biosynthetic process;GO:0071320//cellular response to cAMP;GO:0071398//cellular response to fatty acid;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:1904303//positive regulation of maternal process involved in parturition;GO:0045907//positive regulation of vasoconstriction;GO:1904306//positive regulation of gastro-intestinal system smooth muscle contraction;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:0006935//chemotaxis;GO:0032501//multicellular organismal process;GO:0071548//response to dexamethasone;GO:1904300//positive regulation of transcytosis;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:1904058//positive regulation of sensory perception of pain;GO:0032957//inositol trisphosphate metabolic process;GO:0043315//positive regulation of neutrophil degranulation;GO:0006954//inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006952//defense response","K04279//platelet-activating factor receptor","gi|16758018|ref|NP_445773.1|//platelet-activating factor receptor [Rattus norvegicus]"]
[null,59075,5189,118.852532437197,239.448294749607,-1.01054151766816,"DOWN",0.00187498997875475,"Grk5","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004677//DNA-dependent protein kinase activity;GO:0004676//3-phosphoinositide-dependent protein kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004711//ribosomal protein S6 kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0047696//beta-adrenergic receptor kinase activity;GO:0019912//cyclin-dependent protein kinase activating kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0008545//JUN kinase kinase activity;GO:0060089//molecular transducer activity;GO:0034211//GTP-dependent protein kinase activity;GO:0004703//G-protein coupled receptor kinase activity;GO:0008289//lipid binding;GO:0004705//JUN kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032559//adenyl ribonucleotide binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0042493//response to drug;GO:0007217//tachykinin receptor signaling pathway;GO:0042221//response to chemical;GO:0043066//negative regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0045444//fat cell differentiation;GO:0016055//Wnt signaling pathway;GO:0051726//regulation of cell cycle;GO:0008284//positive regulation of cell proliferation","K08291//G protein-coupled receptor kinase [EC:2.7.11.16]","gi|13540624|ref|NP_110456.1|//G protein-coupled receptor kinase 5 [Rattus norvegicus];gi|3005012|gb|AAC09271.1|//G protein-coupled receptor kinase 5 [Mus musculus]"]
[null,59086,1482,110.377404079981,248.825244436099,-1.1726879998711,"DOWN",{"v":6.37798994661918e-05,"d":"6.38E-05"},"Tgfb1","GO:0031012//extracellular matrix;GO:0044297//cell body;GO:0031091//platelet alpha granule;GO:0043005//neuron projection;GO:0044431//Golgi apparatus part","GO:0042802//identical protein binding;GO:0005160//transforming growth factor beta receptor binding;GO:0046983//protein dimerization activity","GO:0060602//branch elongation of an epithelium;GO:0050863//regulation of T cell activation;GO:0009746//response to hexose;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0030323//respiratory tube development;GO:0043627//response to estrogen;GO:0001837//epithelial to mesenchymal transition;GO:0008285//negative regulation of cell proliferation;GO:0051414//response to cortisol;GO:0010761//fibroblast migration;GO:0032103//positive regulation of response to external stimulus;GO:0060363//cranial suture morphogenesis;GO:0006915//apoptotic process;GO:0070848//response to growth factor;GO:0007096//regulation of exit from mitosis;GO:0045596//negative regulation of cell differentiation;GO:0033273//response to vitamin;GO:0003006//developmental process involved in reproduction;GO:0009206//purine ribonucleoside triphosphate biosynthetic process;GO:0016049//cell growth;GO:0007405//neuroblast proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006814//sodium ion transport;GO:0042476//odontogenesis;GO:0001773//myeloid dendritic cell activation;GO:0030282//bone mineralization;GO:0016573//histone acetylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0051149//positive regulation of muscle cell differentiation;GO:0002260//lymphocyte homeostasis;GO:0042307//positive regulation of protein import into nucleus;GO:0090077//foam cell differentiation;GO:0014706//striated muscle tissue development;GO:0006260//DNA replication;GO:0007162//negative regulation of cell adhesion;GO:0010595//positive regulation of endothelial cell migration;GO:0043405//regulation of MAP kinase activity;GO:0009628//response to abiotic stimulus;GO:0001819//positive regulation of cytokine production;GO:0008366//axon ensheathment;GO:0007431//salivary gland development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0002507//tolerance induction;GO:0007599//hemostasis;GO:0060688//regulation of morphogenesis of a branching structure;GO:0033993//response to lipid;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0045806//negative regulation of endocytosis;GO:0046730//induction of host immune response by virus;GO:0034405//response to fluid shear stress;GO:0002246//wound healing involved in inflammatory response;GO:0000082//G1/S transition of mitotic cell cycle;GO:0030217//T cell differentiation;GO:0016575//histone deacetylation;GO:0007050//cell cycle arrest;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0001934//positive regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007276//gamete generation;GO:0050832//defense response to fungus;GO:0012502//induction of programmed cell death;GO:0010596//negative regulation of endothelial cell migration;GO:0034330//cell junction organization;GO:0045830//positive regulation of isotype switching;GO:0009057//macromolecule catabolic process;GO:0042098//T cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0006887//exocytosis","K13375//transforming growth factor beta-1","gi|11024652|ref|NP_067589.1|//transforming growth factor beta-1 precursor [Rattus norvegicus]"]
[null,59115,907,7.6975055466535,2.8293960757382,1.44389685391721,"UP",0.0391272376055361,"Ninj2","GO:0016021//integral component of membrane","NA","GO:0007155//cell adhesion;GO:0042246//tissue regeneration","NA","gi|11024676|ref|NP_067606.1|//ninjurin-2 [Rattus norvegicus]"]
[null,59326,3744,74.2606314134014,346.597907396183,-2.22259345706159,"DOWN",{"v":1.78193292304997e-05,"d":"1.78E-05"},"Rapgef3","GO:0016020//membrane;GO:0031090//organelle membrane;GO:0031526//brush border membrane;GO:0043025//neuronal cell body;GO:0044424//intracellular part;GO:0030426//growth cone;GO:0030864//cortical actin cytoskeleton;GO:1990796//photoreceptor cell terminal bouton;GO:0070062//extracellular exosome;GO:1990795//rod bipolar cell terminal bouton;GO:0097470//ribbon synapse;GO:0030027//lamellipodium;GO:0005902//microvillus;GO:0009925//basal plasma membrane;GO:0030175//filopodium;GO:0048471//perinuclear region of cytoplasm;GO:0043234//protein complex;GO:1990794//basolateral part of cell;GO:0045177//apical part of cell","GO:0030552//cAMP binding;GO:0044325//ion channel binding;GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity;GO:0016208//AMP binding;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0030695//GTPase regulator activity","GO:0035094//response to nicotine;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0035690//cellular response to drug;GO:0097421//liver regeneration;GO:0007420//brain development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1990791//dorsal root ganglion development;GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0045766//positive regulation of angiogenesis;GO:1904427//positive regulation of calcium ion transmembrane transport;GO:1904426//positive regulation of GTP binding;GO:1901985//positive regulation of protein acetylation;GO:0006468//protein phosphorylation;GO:0045793//positive regulation of cell size;GO:0034242//negative regulation of syncytium formation by plasma membrane fusion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009966//regulation of signal transduction;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0061028//establishment of endothelial barrier;GO:0032486//Rap protein signal transduction;GO:0021510//spinal cord development;GO:0043547//positive regulation of GTPase activity;GO:0071320//cellular response to cAMP;GO:1904453//positive regulation of hydrogen:potassium-exchanging ATPase activity;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0014911//positive regulation of smooth muscle cell migration;GO:0046827//positive regulation of protein export from nucleus;GO:0032966//negative regulation of collagen biosynthetic process;GO:0060840//artery development;GO:0051496//positive regulation of stress fiber assembly;GO:1904474//cellular response to L-dopa;GO:2000615//regulation of histone H3-K9 acetylation","K08014//Rap guanine nucleotide exchange factor 3","gi|78070706|gb|AAI07668.1|//Rap guanine nucleotide exchange factor (GEF) 3 [Rattus norvegicus];gi|672060243|ref|XP_008764000.1|//PREDICTED: rap guanine nucleotide exchange factor 3 isoform X2 [Rattus norvegicus]"]
[null,60324,5341,380.621514089001,1221.65590724853,-1.682408976219,"DOWN",{"v":1.09911129183461e-05,"d":"1.10E-05"},"Synpo","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0030018//Z disc;GO:0005923//bicellular tight junction;GO:0015629//actin cytoskeleton;GO:0032432//actin filament bundle;GO:0043197//dendritic spine;GO:0043296//apical junction complex;GO:0045211//postsynaptic membrane","GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding","GO:0032233//positive regulation of actin filament bundle assembly;GO:0030865//cortical cytoskeleton organization;GO:0032231//regulation of actin filament bundle assembly","K21112//synaptopodin","gi|48428501|sp|Q9Z327.2|SYNPO_RAT//RecName: Full=Synaptopodin;gi|569002902|ref|XP_006525531.1|//PREDICTED: synaptopodin isoform X2 [Mus musculus]"]
[null,60335,2870,69.2457981374495,414.098641533892,-2.58017603427842,"DOWN",{"v":1.54781679423448e-05,"d":"1.55E-05"},"Tgm1","GO:0070062//extracellular exosome;GO:0031224//intrinsic component of membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0016755//transferase activity, transferring amino-acyl groups","GO:0009653//anatomical structure morphogenesis;GO:0030216//keratinocyte differentiation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0031424//keratinization;GO:0018149//peptide cross-linking;GO:0009887//animal organ morphogenesis;GO:0006464//cellular protein modification process;GO:0045787//positive regulation of cell cycle","K05619//transglutaminase 1 [EC:2.3.2.13]","gi|13928912|ref|NP_113847.1|//protein-glutamine gamma-glutamyltransferase K [Rattus norvegicus]"]
[null,60357,3714,20.2396153852115,42.9991184882975,-1.08712520920994,"DOWN",0.0385068185376557,"Prom1","GO:0044421//extracellular region part;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0005903//brush border;GO:0031988//null;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0032420//stereocilium;GO:0070062//extracellular exosome;GO:0044459//plasma membrane part;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005902//microvillus;GO:0071914//prominosome;GO:0009986//cell surface;GO:0042622//photoreceptor outer segment membrane;GO:0031513//null","GO:0042805//actinin binding;GO:0045296//cadherin binding","GO:0072139//glomerular parietal epithelial cell differentiation;GO:0001754//eye photoreceptor cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0010842//retina layer formation;GO:0003407//neural retina development;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0060219//camera-type eye photoreceptor cell differentiation","K06532//prominin 1","gi|158635964|ref|NP_068519.2|//prominin-1 isoform 1 precursor [Rattus norvegicus];gi|158635966|ref|NP_001103607.1|//prominin-1 isoform 2 precursor [Rattus norvegicus] ;gi|148705654|gb|EDL37601.1|//prominin 1, isoform CRA_b, partial [Mus musculus]"]
[null,60414,1509,6.10217869131017,22.2638887720884,-1.86730927388313,"DOWN",0.0048634690476692,"Rhd","GO:0031224//intrinsic component of membrane","GO:0015101//organic cation transmembrane transporter activity","GO:0015696//ammonium transport","K06579//Rhesus blood group glycoprotein","gi|11968076|ref|NP_071950.1|//blood group Rh(D) polypeptide [Rattus norvegicus]"]
[null,60416,2712,31.2121683977765,62.6133687571629,-1.00436213508791,"DOWN",0.0188078799725424,"Pfkp","GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0044444//cytoplasmic part","GO:0003872//6-phosphofructokinase activity;GO:0005524//ATP binding;GO:0070061//fructose binding;GO:0008443//phosphofructokinase activity;GO:0046872//metal ion binding;GO:0043169//cation binding;GO:0032559//adenyl ribonucleotide binding;GO:0070095//fructose-6-phosphate binding;GO:0032403//protein complex binding","GO:0098779//mitophagy in response to mitochondrial depolarization;GO:0016310//phosphorylation;GO:0006007//glucose catabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0051289//protein homotetramerization;GO:0006000//fructose metabolic process;GO:0051260//protein homooligomerization;GO:0061615//glycolytic process through fructose-6-phosphate;GO:0030388//fructose 1,6-bisphosphate metabolic process","K00850//6-phosphofructokinase 1 [EC:2.7.1.11]","gi|149020944|gb|EDL78551.1|//phosphofructokinase, platelet, isoform CRA_b [Rattus norvegicus];gi|57977273|ref|NP_996729.1|//ATP-dependent 6-phosphofructokinase, platelet type [Rattus norvegicus]"]
[null,60628,1726,61.0097897946979,139.738696856804,-1.1956189264058,"DOWN",0.0217541656442698,"Cxcr4","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031410//cytoplasmic vesicle;GO:0030427//site of polarized growth","GO:0017022//myosin binding;GO:0004950//chemokine receptor activity;GO:0019899//enzyme binding;GO:0032182//ubiquitin-like protein binding","GO:0021537//telencephalon development;GO:0042110//T cell activation;GO:0016477//cell migration;GO:0003006//developmental process involved in reproduction;GO:0001525//angiogenesis;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0019058//viral life cycle;GO:0006941//striated muscle contraction;GO:0010959//regulation of metal ion transport;GO:0032101//regulation of response to external stimulus;GO:0012501//programmed cell death;GO:0008037//cell recognition;GO:0007276//gamete generation;GO:0007411//axon guidance;GO:0030855//epithelial cell differentiation","K04189//C-X-C chemokine receptor type 4","gi|59709461|ref|NP_071541.2|//C-X-C chemokine receptor type 4 [Rattus norvegicus]"]
[null,63839,1298,28.5492301672971,60.8840779134175,-1.09261314766782,"DOWN",0.0354324966906662,"Fhl2","GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0031672//A band;GO:0031430//M band;GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0005924//cell-substrate adherens junction","GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding","GO:0055015//ventricular cardiac muscle cell development;GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0055014//atrial cardiac muscle cell development;GO:0043066//negative regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009719//response to endogenous stimulus;GO:0060347//heart trabecula formation;GO:0009725//response to hormone","K14380//four and a half LIM domains protein 2","gi|880911340|ref|XP_005075413.2|//PREDICTED: four and a half LIM domains protein 2 [Mesocricetus auratus];gi|13928940|ref|NP_113865.1|//four and a half LIM domains protein 2 [Rattus norvegicus]"]
[null,63849,2377,21.2004661296426,86.6713821167932,-2.03145972560427,"DOWN",0.000675344645816468,"Mmp8","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding","GO:0032963//collagen metabolic process;GO:0006508//proteolysis;GO:0019538//protein metabolic process;GO:0030574//collagen catabolic process","K01402//matrix metalloproteinase-8 (neutrophil collagenase) [EC:3.4.24.34]","gi|149020725|gb|EDL78530.1|//matrix metallopeptidase 8 [Rattus norvegicus];gi|11560008|ref|NP_071557.1|//neutrophil collagenase precursor [Rattus norvegicus]"]
[null,63865,1940,1130.70655448255,2513.31348523757,-1.15236606571298,"DOWN",0.00301010498237466,"Lgmn","GO:0005768//endosome;GO:0070062//extracellular exosome;GO:0005770//late endosome;GO:0045177//apical part of cell;GO:0005764//lysosome;GO:0000323//lytic vacuole","GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0006775//fat-soluble vitamin metabolic process;GO:0032801//receptor catabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0042221//response to chemical;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:1901185//negative regulation of ERBB signaling pathway;GO:0035264//multicellular organism growth;GO:0003014//renal system process;GO:0019538//protein metabolic process;GO:0010447//response to acidic pH;GO:0006624//vacuolar protein processing;GO:0040015//negative regulation of multicellular organism growth;GO:0006629//lipid metabolic process","K01369//legumain [EC:3.4.22.34]","gi|56388620|gb|AAH87708.1|//Legumain [Rattus norvegicus];gi|31543514|ref|NP_071562.2|//legumain precursor [Rattus norvegicus]"]
[null,64016,1431,130.761306122921,54.2960859220218,1.26801558642357,"UP",0.00957136388054686,"Qtrt1","GO:0043231//intracellular membrane-bounded organelle","GO:0016763//transferase activity, transferring pentosyl groups;GO:0043169//cation binding","GO:0006400//tRNA modification","K00773//queuine tRNA-ribosyltransferase [EC:2.4.2.29]","gi|158186687|ref|NP_071586.2|//queuine tRNA-ribosyltransferase [Rattus norvegicus]"]
[null,64032,2349,116.620939230632,375.802479562554,-1.68814773879892,"DOWN",0.000150053499337576,"Ctgf","GO:0031012//extracellular matrix;GO:0044431//Golgi apparatus part","GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0019838//growth factor binding","GO:0001101//response to acid chemical;GO:0009746//response to hexose;GO:0006950//response to stress;GO:0016049//cell growth;GO:0030323//respiratory tube development;GO:0006259//DNA metabolic process;GO:0043627//response to estrogen;GO:0048869//cellular developmental process;GO:0001932//regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell proliferation;GO:0048870//cell motility;GO:0045989//positive regulation of striated muscle contraction;GO:0033993//response to lipid;GO:0016337//single organismal cell-cell adhesion;GO:0008219//cell death;GO:0006816//calcium ion transport;GO:0031589//cell-substrate adhesion;GO:0032940//secretion by cell;GO:0007568//aging;GO:0031960//response to corticosteroid;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010467//gene expression;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0010952//positive regulation of peptidase activity;GO:0045787//positive regulation of cell cycle","K06827//connective tissue growth factor","gi|149032916|gb|EDL87771.1|//connective tissue growth factor [Rattus norvegicus]"]
[null,64043,5010,13.0315097839257,39.4009696297915,-1.59622689475987,"DOWN",0.00539757181199968,"Gcnt1","GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part","GO:0008375//acetylglucosaminyltransferase activity","GO:0006486//protein glycosylation;GO:0009887//animal organ morphogenesis;GO:0043434//response to peptide hormone","K00727//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]","gi|11560101|ref|NP_071612.1|//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [Rattus norvegicus]"]
[null,64158,1621,74.007115660889,148.953128821895,-1.00912253306191,"DOWN",0.00403183175894193,"Tuba1a","GO:0005874//microtubule;GO:0044444//cytoplasmic part","GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0046983//protein dimerization activity","GO:0006458//'de novo' protein folding;GO:0022402//cell cycle process;GO:0007017//microtubule-based process;GO:0009207//purine ribonucleoside triphosphate catabolic process;GO:0043623//cellular protein complex assembly","K07374//tubulin alpha","gi|505846589|ref|XP_004616768.1|//PREDICTED: tubulin alpha-1B chain isoform X2 [Sorex araneus];gi|488552971|ref|XP_004467830.1|//PREDICTED: tubulin alpha-1D chain [Dasypus novemcinctus]"]
[null,64160,1024,35.5786927709347,71.4368368284131,-1.005654696168,"DOWN",0.0451281650164353,"Basp1","NA","NA","NA","NA","NA"]
[null,64191,3510,1173.17955404644,514.861218887351,1.18816832280515,"UP",0.000744275164944839,"Dhcr7","GO:0031224//intrinsic component of membrane;GO:0031965//nuclear membrane","GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","GO:0001944//vasculature development;GO:0008203//cholesterol metabolic process;GO:0008283//cell proliferation;GO:0040007//growth;GO:0050810//regulation of steroid biosynthetic process;GO:0030323//respiratory tube development;GO:0048869//cellular developmental process","K00213//7-dehydrocholesterol reductase [EC:1.3.1.21]","gi|672039485|ref|XP_008758392.1|//PREDICTED: 7-dehydrocholesterol reductase isoform X2 [Rattus norvegicus];gi|755524052|ref|XP_006508539.2|//PREDICTED: 7-dehydrocholesterol reductase isoform X2 [Mus musculus]"]
[null,64195,1463,41.3956304295035,166.097163403064,-2.00447703996359,"DOWN",{"v":3.55431973765372e-05,"d":"3.55E-05"},"Clec10a","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding","GO:0002248//connective tissue replacement involved in inflammatory response wound healing","K06721//C-type lectin domain family 10 member A","gi|564372953|ref|XP_006246865.1|//PREDICTED: C-type lectin domain family 10 member A isoform X2 [Rattus norvegicus];gi|61889079|ref|NP_071788.2|//C-type lectin domain family 10 member A [Rattus norvegicus]"]
[null,64203,1548,14.6640747658943,39.8613077215905,-1.44270299444904,"DOWN",0.0235812032626882,"Bcat2","GO:0043231//intracellular membrane-bounded organelle","GO:0004084//branched-chain-amino-acid transaminase activity","GO:0007589//body fluid secretion;GO:0008652//cellular amino acid biosynthetic process;GO:0009063//cellular amino acid catabolic process;GO:0006551//leucine metabolic process;GO:0006549//isoleucine metabolic process","K00826//branched-chain amino acid aminotransferase [EC:2.6.1.42]","gi|11693174|ref|NP_071795.1|//branched-chain-amino-acid aminotransferase, mitochondrial precursor [Rattus norvegicus]"]
[null,64362,2169,29.1604323858474,66.5793188335608,-1.19106199862715,"DOWN",0.0303319257981202,"Des","GO:0005913//cell-cell adherens junction;GO:0031674//I band;GO:0005882//intermediate filament","GO:0005198//structural molecule activity;GO:0005488//binding","GO:0048513//animal organ development","K07610//desmin","gi|829929071|ref|XP_012595618.1|//PREDICTED: desmin [Microcebus murinus]"]
[null,64442,4571,39.7545456238124,94.5589290549844,-1.25009386528083,"DOWN",0.0048703253954792,"St3gal2","GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0005576//extracellular region","GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity","GO:0006464//cellular protein modification process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation;GO:0001574//ganglioside biosynthetic process","K03368//beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.99.4]","gi|589922499|ref|XP_006974157.1|//PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 isoform X1 [Peromyscus maniculatus bairdii] "]
[null,64455,3682,1362.07716650821,595.102782393139,1.19459767123535,"UP",0.0204087702411916,"Rasd1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part","GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity","GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0009207//purine ribonucleoside triphosphate catabolic process","K07844//RASD family, member 2;K12665//cytochrome P450 family 26 subfamily C;K07843//RAS, dexamethasone-induced Ras-related protein 1","gi|959037096|ref|XP_014726531.1|//PREDICTED: dexamethasone-induced Ras-related protein 1 [Sturnus vulgaris];gi|625251441|ref|XP_007617037.1|//PREDICTED: dexamethasone-induced Ras-related protein 1 isoform X1 [Cricetulus griseus]"]
[null,64475,2465,279.424413546276,559.408300286762,-1.00144358439643,"DOWN",0.00626414075134417,"P4ha1","GO:0016020//membrane;GO:0044432//endoplasmic reticulum part;GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0005739//mitochondrion","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019842//vitamin binding;GO:0005506//iron ion binding;GO:0046914//transition metal ion binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0004656//procollagen-proline 4-dioxygenase activity","GO:0019471//4-hydroxyproline metabolic process;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0055114//oxidation-reduction process","K00472//prolyl 4-hydroxylase [EC:1.14.11.2]","gi|51036657|ref|NP_742059.2|//prolyl 4-hydroxylase subunit alpha-1 precursor [Rattus norvegicus];gi|74225936|dbj|BAE28745.1|//unnamed protein product [Mus musculus]"]
[null,64537,3177,92.7117319759528,217.749282734349,-1.23184414882011,"DOWN",0.0133755170586773,"Hpse","GO:0031012//extracellular matrix;GO:0005764//lysosome","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043167//ion binding","GO:0044238//primary metabolic process","K07964//heparanase [EC:3.2.1.166]","gi|12018276|ref|NP_072127.1|//heparanase precursor [Rattus norvegicus]"]
[null,64547,5034,114.892647364537,285.025063754259,-1.31080231396682,"DOWN",0.00011735307248311,"Bcl2l11","GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0044444//cytoplasmic part","GO:0015631//tubulin binding;GO:0046983//protein dimerization activity","GO:0040008//regulation of growth;GO:0048732//gland development;GO:0048232//male gamete generation;GO:0043009//chordate embryonic development;GO:0070227//lymphocyte apoptotic process;GO:0008406//gonad development;GO:0048534//hematopoietic or lymphoid organ development;GO:0001836//release of cytochrome c from mitochondria;GO:0042476//odontogenesis;GO:0031589//cell-substrate adhesion;GO:0007417//central nervous system development;GO:0032461//positive regulation of protein oligomerization;GO:0007423//sensory organ development;GO:0050793//regulation of developmental process;GO:0051726//regulation of cell cycle;GO:0002260//lymphocyte homeostasis;GO:0048646//anatomical structure formation involved in morphogenesis","K05727//dedicator of cytokinesis protein 3;K16341//Bcl-2-like protein 11","gi|149023239|gb|EDL80133.1|//BCL2-like 11 (apoptosis facilitator), isoform CRA_c [Rattus norvegicus];gi|47208488|emb|CAF93086.1|//unnamed protein product, partial [Tetraodon nigroviridis];gi|25282461|ref|NP_741986.1|//bcl-2-like protein 11 isoform BOD-M [Rattus norvegicus];gi|672046963|ref|XP_006235047.2|//PREDICTED: bcl-2-like protein 11 isoform X3 [Rattus norvegicus]"]
[null,64826,2634,50.7728180958776,110.650922368691,-1.12388723448074,"DOWN",0.0309894952572886,"Foxq1","GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex","GO:0035258//steroid hormone receptor binding;GO:0043566//structure-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0030234//enzyme regulator activity;GO:0043565//sequence-specific DNA binding;GO:0019899//enzyme binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000737//DNA catabolic process, endonucleolytic;GO:0001942//hair follicle development;GO:0010952//positive regulation of peptidase activity","K09410//forkhead box protein Q","gi|550513|gb|AAA74561.1|//HNF-3/forkhead homolog-1 [Rattus norvegicus]"]
[null,64846,3246,586.617931280558,1436.60225528476,-1.29216760942456,"DOWN",0.000235683857781965,"Slc13a3","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane","GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0015362//high-affinity sodium:dicarboxylate symporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015137//citrate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity","GO:0035725//sodium ion transmembrane transport;GO:0006842//tricarboxylic acid transport;GO:0071422//succinate transmembrane transport;GO:1903825//organic acid transmembrane transport;GO:0006865//amino acid transport;GO:0089712//L-aspartate transmembrane transport;GO:0015746//citrate transport;GO:0006814//sodium ion transport;GO:0015744//succinate transport","K14445//solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5","gi|162138928|ref|NP_074057.2|//solute carrier family 13 member 3 [Rattus norvegicus];gi|149042880|gb|EDL96454.1|//solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 [Rattus norvegicus]"]
[null,65030,1992,2951.13047962206,1130.60444449232,1.38417343522525,"UP",0.00580083159446988,"Ephx2","GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0005924//cell-substrate adherens junction","GO:0046872//metal ion binding;GO:0016803//ether hydrolase activity;GO:0016791//phosphatase activity","GO:0008217//regulation of blood pressure;GO:0007600//sensory perception;GO:0042221//response to chemical;GO:0006725//cellular aromatic compound metabolic process;GO:0002538//arachidonic acid metabolite production involved in inflammatory response;GO:0001676//long-chain fatty acid metabolic process;GO:0006796//phosphate-containing compound metabolic process","K08726//soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]","gi|12621098|ref|NP_075225.1|//bifunctional epoxide hydrolase 2 [Rattus norvegicus]"]
[null,66021,4344,345.066998311502,1107.7216987374,-1.68264705947301,"DOWN",{"v":8.3720256664498e-08,"d":"8.37E-08"},"Cybb","GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0045335//phagocytic vesicle;GO:0044297//cell body;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0043020//NADPH oxidase complex;GO:0005739//mitochondrion","GO:0052693//epoxyqueuosine reductase activity;GO:0005506//iron ion binding;GO:0043826//sulfur oxygenase reductase activity;GO:0046982//protein heterodimerization activity;GO:0050660//flavin adenine dinucleotide binding;GO:0043738//reduced coenzyme F420 dehydrogenase activity;GO:0046983//protein dimerization activity;GO:0008748//N-ethylmaleimide reductase activity;GO:0043914//NADPH:sulfur oxidoreductase activity;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0009055//electron carrier activity;GO:0020037//heme binding;GO:0005244//voltage-gated ion channel activity;GO:0043883//malolactic enzyme activity;GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0050662//coenzyme binding","GO:0006801//superoxide metabolic process;GO:0034220//ion transmembrane transport;GO:0055114//oxidation-reduction process;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0042493//response to drug;GO:0042221//response to chemical;GO:0042743//hydrogen peroxide metabolic process;GO:0034765//regulation of ion transmembrane transport;GO:0006091//generation of precursor metabolites and energy;GO:0045730//respiratory burst;GO:0006954//inflammatory response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0006952//defense response;GO:0031667//response to nutrient levels;GO:0050665//hydrogen peroxide biosynthetic process","K08008//NADPH oxidase","gi|13027416|ref|NP_076455.1|//cytochrome b-245, beta polypeptide [Rattus norvegicus];gi|161333819|ref|NP_031833.3|//cytochrome b-245 heavy chain [Mus musculus]"]
[null,78962,8020,164.487410453528,441.303166082046,-1.42379293069767,"DOWN",0.00432057446096835,"Per3","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0060089//molecular transducer activity;GO:0031625//ubiquitin protein ligase binding;GO:0019900//kinase binding;GO:0005488//binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023052//signaling;GO:0032922//circadian regulation of gene expression;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0045187//regulation of circadian sleep/wake cycle, sleep","K02633//period circadian protein","gi|166197716|ref|NP_076468.2|//period circadian protein homolog 3 [Rattus norvegicus]"]
[null,78967,2933,70.3037374356588,155.898489680147,-1.14893365955917,"DOWN",0.00910750643456054,"Mcam","GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body","NA","GO:0016337//single organismal cell-cell adhesion","K06534//melanoma cell adhesion molecule","gi|77176454|ref|NP_001029181.1|//cell surface glycoprotein MUC18 isoform 2 precursor [Rattus norvegicus];gi|77176452|ref|NP_076473.2|//cell surface glycoprotein MUC18 isoform 1 precursor [Rattus norvegicus]"]
[null,79128,4669,295.76971860738,770.677240964936,-1.38165243255701,"DOWN",0.00331836384658964,"Dab2","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0005925//focal adhesion;GO:0030136//clathrin-coated vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0012505//endomembrane system;GO:0030132//clathrin coat of coated pit;GO:0070022//transforming growth factor beta receptor homodimeric complex;GO:0005730//nucleolus;GO:0030665//clathrin-coated vesicle membrane","GO:0035612//AP-2 adaptor complex binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0038024//cargo receptor activity;GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0035615//clathrin adaptor activity;GO:0046332//SMAD binding","GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:0030335//positive regulation of cell migration;GO:0002092//positive regulation of receptor internalization;GO:0043009//chordate embryonic development;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031331//positive regulation of cellular catabolic process;GO:2000370//positive regulation of clathrin-dependent endocytosis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0007492//endoderm development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043393//regulation of protein binding;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0035026//leading edge cell differentiation;GO:0007257//activation of JUN kinase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:2000860//positive regulation of aldosterone secretion;GO:2000643//positive regulation of early endosome to late endosome transport;GO:0003008//system process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0016049//cell growth;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0001932//regulation of protein phosphorylation;GO:0010977//negative regulation of neuron projection development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0048268//clathrin coat assembly;GO:0006897//endocytosis;GO:0006907//pinocytosis;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0000902//cell morphogenesis;GO:0030308//negative regulation of cell growth;GO:0001921//positive regulation of receptor recycling;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0007588//excretion;GO:0001701//in utero embryonic development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:1902074//response to salt;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K12475//disabled homolog 2","gi|3157995|gb|AAC33406.1|//DOC-2 p59 isoform [Rattus norvegicus];gi|13162357|ref|NP_077073.1|//disabled homolog 2 [Rattus norvegicus]"]
[null,79252,4395,396.703741319129,906.626045896571,-1.1924456044824,"DOWN",0.00187968396597197,"Adamts1","GO:0031982//vesicle;GO:0005578//proteinaceous extracellular matrix","GO:0004175//endopeptidase activity;GO:0005539//glycosaminoglycan binding;GO:0046914//transition metal ion binding","GO:0022602//ovulation cycle process;GO:0001525//angiogenesis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0060343//trabecula formation","K08617//a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-]","gi|148747506|ref|NP_077376.2|//A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor [Rattus norvegicus]"]
[null,80878,2793,31.7448645636128,71.3421638797322,-1.16823175204432,"DOWN",0.0372556953724713,"Slc16a3","GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0031965//nuclear membrane;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope;GO:0015629//actin cytoskeleton","GO:0015291//secondary active transmembrane transporter activity;GO:0044822//poly(A) RNA binding;GO:0015129//lactate transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity","GO:0006820//anion transport;GO:0046942//carboxylic acid transport;GO:0035879//plasma membrane lactate transport","K08180//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 3","gi|13540632|ref|NP_110461.1|//monocarboxylate transporter 4 [Rattus norvegicus];gi|589950100|ref|XP_006987706.1|//PREDICTED: monocarboxylate transporter 4 isoform X1 [Peromyscus maniculatus bairdii]"]
[null,81506,1411,9.45065430270227,24.1362009481771,-1.35271249208089,"DOWN",0.0285633094297455,"Bst1","GO:0031224//intrinsic component of membrane","GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds","NA","K18152//ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]","gi|13540658|ref|NP_110475.1|//ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 precursor [Rattus norvegicus]"]
[null,81508,1978,22860.6023327421,9760.07241955269,1.22789965857215,"UP",0.013080667312697,"Bhmt","GO:0032991//macromolecular complex","GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0008172//S-methyltransferase activity","GO:0008213//protein alkylation;GO:0000097//sulfur amino acid biosynthetic process","K00544//betaine-homocysteine S-methyltransferase [EC:2.1.1.5]","gi|13540663|ref|NP_110477.1|//betaine--homocysteine S-methyltransferase 1 [Rattus norvegicus];gi|532086665|ref|XP_005329051.1|//PREDICTED: betaine--homocysteine S-methyltransferase 1 [Ictidomys tridecemlineatus]"]
[null,81520,1540,58.9768486744352,133.300580037735,-1.1764624164486,"DOWN",0.00643103557453567,"Marcksl1","GO:0016020//membrane","NA","GO:0006810//transport;GO:0008283//cell proliferation","K13536//MARCKS-related protein","gi|672013322|ref|XP_008772695.1|//PREDICTED: MARCKS-related protein-like [Rattus norvegicus]"]
[null,81521,2099,133.568706453057,310.302864148283,-1.21609497200351,"DOWN",0.0270765097269876,"Msn","GO:0031981//nuclear lumen;GO:0030141//secretory granule;GO:0044459//plasma membrane part;GO:0031254//cell trailing edge;GO:0043232//intracellular non-membrane-bounded organelle;GO:0005902//microvillus;GO:0030175//filopodium","GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity","GO:0002376//immune system process;GO:0016337//single organismal cell-cell adhesion;GO:0022406//membrane docking","K05763//moesin","gi|13540689|ref|NP_110490.1|//moesin [Rattus norvegicus]"]
[null,81633,1412,54.0203404045605,190.69700978026,-1.81970758567644,"DOWN",0.00201850794151257,"Acta2","GO:0032432//actin filament bundle;GO:0043292//contractile fiber","GO:0032559//adenyl ribonucleotide binding;GO:0005198//structural molecule activity","GO:0008015//blood circulation;GO:0007015//actin filament organization;GO:0006939//smooth muscle contraction;GO:0048747//muscle fiber development;GO:0051707//response to other organism","K12313//actin, aortic smooth muscle","gi|625206860|ref|XP_003505997.2|//PREDICTED: actin, aortic smooth muscle isoform X1 [Cricetulus griseus]"]
[null,81639,2216,124.934525616137,816.696877306123,-2.70862849111884,"DOWN",{"v":2.34074934244263e-05,"d":"2.34E-05"},"Alox15","GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0008200//ion channel inhibitor activity;GO:0046914//transition metal ion binding;GO:0016803//ether hydrolase activity","GO:0006884//cell volume homeostasis;GO:0000038//very long-chain fatty acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0006873//cellular ion homeostasis;GO:0016049//cell growth;GO:0001503//ossification;GO:0006691//leukotriene metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0008283//cell proliferation;GO:0006952//defense response","K00460//arachidonate 15-lipoxygenase [EC:1.13.11.33]","gi|31542125|ref|NP_112272.2|//arachidonate 15-lipoxygenase [Rattus norvegicus]"]
[null,81680,5824,123.440049047821,458.611491208717,-1.89346196402737,"DOWN",0.000992001415367364,"Lifr","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0004897//ciliary neurotrophic factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0019955//cytokine binding;GO:0004923//leukemia inhibitory factor receptor activity;GO:0046982//protein heterodimerization activity;GO:0019838//growth factor binding;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005126//cytokine receptor binding","GO:0031100//animal organ regeneration;GO:0014070//response to organic cyclic compound;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0048858//cell projection morphogenesis;GO:0008283//cell proliferation;GO:0048812//neuron projection morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0008284//positive regulation of cell proliferation","K05058//leukemia inhibitory factor receptor","gi|13591979|ref|NP_112310.1|//leukemia inhibitory factor receptor precursor [Rattus norvegicus];gi|149016481|gb|EDL75699.1|//leukemia inhibitory factor receptor, isoform CRA_a [Rattus norvegicus];gi|7305235|ref|NP_038612.1|//leukemia inhibitory factor receptor isoform 1 precursor [Mus musculus]"]
[null,81683,551,179.594059733931,61.1801038676015,1.55360517085837,"UP",0.0164363973117035,"Mif","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part","GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0005102//receptor binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds","GO:0009968//negative regulation of signal transduction;GO:0014909//smooth muscle cell migration;GO:0051260//protein homooligomerization;GO:0043627//response to estrogen;GO:0032571//response to vitamin K;GO:0030888//regulation of B cell proliferation;GO:0006813//potassium ion transport;GO:0010737//protein kinase A signaling;GO:0032103//positive regulation of response to external stimulus;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0031960//response to corticosteroid;GO:0008544//epidermis development;GO:0042770//signal transduction in response to DNA damage;GO:0007631//feeding behavior;GO:0034614//cellular response to reactive oxygen species;GO:0048232//male gamete generation;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0006110//regulation of glycolytic process;GO:0002237//response to molecule of bacterial origin;GO:0007050//cell cycle arrest;GO:0010828//positive regulation of glucose transport;GO:0050707//regulation of cytokine secretion;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0043434//response to peptide hormone;GO:0002526//acute inflammatory response;GO:0007417//central nervous system development;GO:0002684//positive regulation of immune system process;GO:0007568//aging;GO:0010467//gene expression;GO:0006693//prostaglandin metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0008284//positive regulation of cell proliferation","K07253//phenylpyruvate tautomerase [EC:5.3.2.1]","gi|13591985|ref|NP_112313.1|//macrophage migration inhibitory factor [Rattus norvegicus]"]
[null,81686,3053,56.3804228304039,136.193178145144,-1.2723882385242,"DOWN",0.00223585556545895,"Mmp2","GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0030016//myofibril","GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding","GO:0014070//response to organic cyclic compound;GO:0002009//morphogenesis of an epithelium;GO:0019229//regulation of vasoconstriction;GO:0001568//blood vessel development;GO:0009628//response to abiotic stimulus;GO:0001503//ossification;GO:0000302//response to reactive oxygen species;GO:0032355//response to estradiol;GO:0070555//response to interleukin-1;GO:0048870//cell motility;GO:0022602//ovulation cycle process;GO:0031103//axon regeneration;GO:0009605//response to external stimulus;GO:0060343//trabecula formation;GO:0006915//apoptotic process;GO:0032963//collagen metabolic process;GO:0007155//cell adhesion;GO:0019538//protein metabolic process;GO:0040007//growth","K01398//matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]","gi|146262019|ref|NP_112316.2|//72 kDa type IV collagenase precursor [Rattus norvegicus]"]
[null,81687,2986,15.5185371256569,42.8072926959257,-1.46386403014717,"DOWN",0.0181487062868184,"Mmp9","GO:0031012//extracellular matrix;GO:0032991//macromolecular complex","GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding","GO:0014070//response to organic cyclic compound;GO:0030335//positive regulation of cell migration;GO:0006950//response to stress;GO:0002237//response to molecule of bacterial origin;GO:0009628//response to abiotic stimulus;GO:0043627//response to estrogen;GO:0070555//response to interleukin-1;GO:0031668//cellular response to extracellular stimulus;GO:0055098//response to low-density lipoprotein particle;GO:0043062//extracellular structure organization;GO:0006915//apoptotic process;GO:0002684//positive regulation of immune system process;GO:0032963//collagen metabolic process;GO:0045765//regulation of angiogenesis;GO:0019538//protein metabolic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0040007//growth;GO:0033273//response to vitamin;GO:0048167//regulation of synaptic plasticity","K01403//matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]","gi|13591993|ref|NP_112317.1|//matrix metalloproteinase-9 precursor [Rattus norvegicus]"]
[null,81730,1697,11.7597692515572,39.3774493469686,-1.74350991236865,"DOWN",0.00180850601296164,"Fez1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043005//neuron projection","GO:0015631//tubulin binding;GO:0019901//protein kinase binding","GO:0070848//response to growth factor;GO:0051649//establishment of localization in cell;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0045597//positive regulation of cell differentiation","K16502//cadherin-related family member 2","gi|13994121|ref|NP_112328.1|//fasciculation and elongation protein zeta-1 [Rattus norvegicus]"]
[null,81782,1750,31.4871028362467,81.5550263774133,-1.37301277588312,"DOWN",0.0417978398865462,"Soat1","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane","GO:0004772//sterol O-acyltransferase activity;GO:0032934//sterol binding;GO:0005504//fatty acid binding","GO:0019915//lipid storage;GO:0034377//plasma lipoprotein particle assembly;GO:0016125//sterol metabolic process;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0030301//cholesterol transport;GO:0034434//sterol esterification;GO:0090077//foam cell differentiation","K00637//sterol O-acyltransferase [EC:2.3.1.26]","gi|13592087|ref|NP_112380.1|//sterol O-acyltransferase 1 [Rattus norvegicus]"]
[null,81809,2880,15.7673210989758,43.889692800322,-1.47694460826705,"DOWN",0.0125028492588858,"Tgfb2","GO:0044297//cell body;GO:0031091//platelet alpha granule;GO:0043005//neuron projection;GO:0044431//Golgi apparatus part;GO:0005578//proteinaceous extracellular matrix","GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0005160//transforming growth factor beta receptor binding;GO:0046983//protein dimerization activity","GO:0014706//striated muscle tissue development;GO:0032872//regulation of stress-activated MAPK cascade;GO:0033627//cell adhesion mediated by integrin;GO:0030323//respiratory tube development;GO:0043627//response to estrogen;GO:0007420//brain development;GO:0009628//response to abiotic stimulus;GO:0007431//salivary gland development;GO:0022008//neurogenesis;GO:0043065//positive regulation of apoptotic process;GO:0008016//regulation of heart contraction;GO:0001837//epithelial to mesenchymal transition;GO:0007599//hemostasis;GO:0033189//response to vitamin A;GO:0045597//positive regulation of cell differentiation;GO:0014855//striated muscle cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0009611//response to wounding;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0010692//regulation of alkaline phosphatase activity;GO:0016337//single organismal cell-cell adhesion;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0060363//cranial suture morphogenesis;GO:0043029//T cell homeostasis;GO:0030198//extracellular matrix organization;GO:0006606//protein import into nucleus;GO:0034405//response to fluid shear stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0051726//regulation of cell cycle;GO:0048598//embryonic morphogenesis;GO:0048771//tissue remodeling;GO:0003006//developmental process involved in reproduction;GO:0035051//cardiocyte differentiation;GO:0016049//cell growth;GO:0032906//transforming growth factor beta2 production;GO:0001944//vasculature development;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0017145//stem cell division;GO:0042417//dopamine metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0048534//hematopoietic or lymphoid organ development;GO:0012502//induction of programmed cell death;GO:0045165//cell fate commitment;GO:0010631//epithelial cell migration;GO:0034330//cell junction organization;GO:0030595//leukocyte chemotaxis;GO:0048565//digestive tract development;GO:0002684//positive regulation of immune system process;GO:0030278//regulation of ossification;GO:0035270//endocrine system development;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0001775//cell activation;GO:0009967//positive regulation of signal transduction;GO:0022402//cell cycle process;GO:0048818//positive regulation of hair follicle maturation;GO:0007423//sensory organ development;GO:0006887//exocytosis","K13376//transforming growth factor beta-2","gi|13592109|ref|NP_112393.1|//transforming growth factor beta-2 precursor [Rattus norvegicus]"]
[null,81818,1796,463.581047968448,1243.09709171843,-1.4230454893659,"DOWN",{"v":5.70912382060627e-06,"d":"5.71E-06"},"Vim","GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0044444//cytoplasmic part;GO:0043005//neuron projection","GO:0019900//kinase binding;GO:0005198//structural molecule activity","GO:0021782//glial cell development;GO:0048708//astrocyte differentiation;GO:0045104//intermediate filament cytoskeleton organization;GO:0010975//regulation of neuron projection development","K07606//vimentin","gi|524962788|ref|XP_005081318.1|//PREDICTED: vimentin [Mesocricetus auratus]"]
[null,83509,2674,158.883469563268,317.94765756882,-1.00082024735269,"DOWN",0.032180498072102,"Slc7a7","GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0044459//plasma membrane part;GO:0005887//integral component of plasma membrane","GO:0015174//basic amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0015297//antiporter activity","GO:0015807//L-amino acid transport;GO:1990822//basic amino acid transmembrane transport;GO:0006865//amino acid transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0003333//amino acid transmembrane transport;GO:0000821//regulation of arginine metabolic process","K13867//solute carrier family 7 (L-type amino acid transporter), member 7","gi|568987117|ref|XP_006518809.1|//PREDICTED: Y+L amino acid transporter 1 isoform X2 [Mus musculus];gi|110625647|ref|NP_035535.2|//Y+L amino acid transporter 1 [Mus musculus];gi|13786176|ref|NP_112631.1|//Y+L amino acid transporter 1 [Rattus norvegicus]"]
[null,83512,1706,2826.55026362965,764.06965778331,1.88726627694579,"UP",0.000672442434336202,"Fads2","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0005506//iron ion binding;GO:0016215//acyl-CoA desaturase activity","GO:0000038//very long-chain fatty acid metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization","K10226//acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]","gi|13786182|ref|NP_112634.1|//fatty acid desaturase 2 [Rattus norvegicus]"]
[null,83535,3051,23.4274256309103,7.33078679925251,1.67615847604068,"UP",0.00989229883522182,"Kcnj11","GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma","GO:0005515//protein binding;GO:0005242//inward rectifier potassium channel activity;GO:0032559//adenyl ribonucleotide binding;GO:0031420//alkali metal ion binding","GO:0048545//response to steroid hormone;GO:0003008//system process;GO:0006873//cellular ion homeostasis;GO:0071805//potassium ion transmembrane transport;GO:0019318//hexose metabolic process;GO:0050796//regulation of insulin secretion","K05004//potassium inwardly-rectifying channel subfamily J member 11","gi|19923693|ref|NP_112648.2|//ATP-sensitive inward rectifier potassium channel 11 [Rattus norvegicus]"]
[null,83585,1460,132.580787224283,291.061786128655,-1.13445371434545,"DOWN",0.0442335040401251,"Gda","NA","GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding","NA","K01487//guanine deaminase [EC:3.5.4.3]","gi|148747414|ref|NP_113964.2|//guanine deaminase [Rattus norvegicus]"]
[null,83681,1972,411.325252304486,896.950200251802,-1.12474824193452,"DOWN",0.00672530244332944,"Cish","GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0005488//binding","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0040008//regulation of growth;GO:0046426//negative regulation of JAK-STAT cascade;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway","K04701//cytokine inducible SH2-containing protein","gi|198278490|ref|NP_113992.1|//cytokine-inducible SH2-containing protein [Rattus norvegicus]"]
[null,83727,8395,130.875865016673,382.326609974257,-1.54660654280179,"DOWN",0.00144648111557832,"Fbn1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001527//microfibril;GO:0043205//fibril;GO:0005604//basement membrane","GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005198//structural molecule activity;GO:0005179//hormone activity","GO:0030514//negative regulation of BMP signaling pathway;GO:0001656//metanephros development;GO:0048513//animal organ development;GO:0043010//camera-type eye development;GO:0007507//heart development;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0035582//sequestering of BMP in extracellular matrix;GO:0048050//post-embryonic eye morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0048048//embryonic eye morphogenesis;GO:0001501//skeletal system development","K06825//fibrillin 1","gi|149023175|gb|EDL80069.1|//fibrillin 1, isoform CRA_a [Rattus norvegicus];gi|13929178|ref|NP_114013.1|//fibrillin-1 precursor [Rattus norvegicus]"]
[null,83731,6466,12.1788295945621,71.6697125969417,-2.55698807461527,"DOWN",0.000123015112865366,"Kcnma1","GO:0030425//dendrite;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0031090//organelle membrane;GO:0048787//presynaptic active zone membrane;GO:0043025//neuronal cell body;GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0033267//axon part;GO:0005739//mitochondrion;GO:0045211//postsynaptic membrane;GO:0008076//voltage-gated potassium channel complex;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0043195//terminal bouton;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane;GO:0044444//cytoplasmic part","GO:0005249//voltage-gated potassium channel activity;GO:0015269//calcium-activated potassium channel activity;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0042803//protein homodimerization activity;GO:0003779//actin binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0060072//large conductance calcium-activated potassium channel activity;GO:0032403//protein complex binding","GO:0021700//developmental maturation;GO:0046541//saliva secretion;GO:0034220//ion transmembrane transport;GO:0060113//inner ear receptor cell differentiation;GO:0008344//adult locomotory behavior;GO:0051260//protein homooligomerization;GO:0009628//response to abiotic stimulus;GO:0030001//metal ion transport;GO:0043627//response to estrogen;GO:0060087//relaxation of vascular smooth muscle;GO:0060083//smooth muscle contraction involved in micturition;GO:0060004//reflex;GO:0019218//regulation of steroid metabolic process;GO:0032344//regulation of aldosterone metabolic process;GO:0006884//cell volume homeostasis;GO:0045909//positive regulation of vasodilation;GO:0051289//protein homotetramerization;GO:0009268//response to pH;GO:0014832//urinary bladder smooth muscle contraction;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0048545//response to steroid hormone;GO:0048469//cell maturation;GO:0031960//response to corticosteroid;GO:0051592//response to calcium ion;GO:0042491//auditory receptor cell differentiation;GO:0001508//action potential;GO:0007628//adult walking behavior;GO:0045475//locomotor rhythm;GO:0050885//neuromuscular process controlling balance;GO:0007589//body fluid secretion;GO:0045986//negative regulation of smooth muscle contraction;GO:0006970//response to osmotic stress;GO:0006950//response to stress;GO:0034465//response to carbon monoxide;GO:0003014//renal system process;GO:0019228//neuronal action potential;GO:0030007//cellular potassium ion homeostasis;GO:0010038//response to metal ion;GO:0042311//vasodilation;GO:0043525//positive regulation of neuron apoptotic process;GO:0045794//negative regulation of cell volume;GO:0034765//regulation of ion transmembrane transport;GO:0060082//eye blink reflex;GO:0007267//cell-cell signaling;GO:0048511//rhythmic process;GO:0007568//aging;GO:0006875//cellular metal ion homeostasis;GO:0007605//sensory perception of sound;GO:0007268//chemical synaptic transmission;GO:0050905//neuromuscular process;GO:1904348//negative regulation of small intestine smooth muscle contraction;GO:0071805//potassium ion transmembrane transport;GO:0050954//sensory perception of mechanical stimulus","K04936//potassium large conductance calcium-activated channel subfamily M alpha member 1","gi|13929184|ref|NP_114016.1|//calcium-activated potassium channel subunit alpha-1 [Rattus norvegicus]"]
[null,83792,5055,79.2702230354206,218.162598351041,-1.4605528475012,"DOWN",0.00110814644401135,"Scd2","GO:0031227//intrinsic component of endoplasmic reticulum membrane","GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity","GO:0044126//regulation of growth of symbiont in host;GO:0045444//fat cell differentiation;GO:0006631//fatty acid metabolic process;GO:0042742//defense response to bacterium;GO:0034434//sterol esterification;GO:0008366//axon ensheathment","K00507//stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]","gi|13929208|ref|NP_114029.1|//acyl-CoA desaturase 2 [Rattus norvegicus]"]
[null,83838,4389,36.4760137494397,95.8729042087445,-1.39417506110274,"DOWN",0.00342726164038353,"Ltbp3","NA","NA","NA","K08023//latent transforming growth factor beta binding protein 2/3/4","gi|300797036|ref|NP_001178490.1|//latent-transforming growth factor beta-binding protein 3 precursor [Rattus norvegicus]"]
[null,83842,3886,3229.98841155425,1436.35753368095,1.16911408381839,"UP",0.0128532102753024,"Crot","GO:0044439//peroxisomal part","GO:0016406//carnitine O-acyltransferase activity","GO:0032787//monocarboxylic acid metabolic process;GO:0009719//response to endogenous stimulus;GO:0015908//fatty acid transport;GO:0042221//response to chemical;GO:0006629//lipid metabolic process","K05940//carnitine O-octanoyltransferase [EC:2.3.1.137]","gi|564345556|ref|XP_006236066.1|//PREDICTED: peroxisomal carnitine O-octanoyltransferase isoform X2 [Rattus norvegicus];gi|537246340|gb|ERE87938.1|//peroxisomal carnitine O-octanoyltransferase isoform 1 [Cricetulus griseus]"]
[null,84007,2093,14.112449404879,35.3046619565065,-1.32289029422844,"DOWN",0.0267043791971254,"C3ar1","GO:0031224//intrinsic component of membrane","GO:0004942//null;GO:0001848//complement binding","GO:0045765//regulation of angiogenesis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0051480//regulation of cytosolic calcium ion concentration","K04009//C3a anaphylatoxin chemotactic receptor","gi|14091740|ref|NP_114449.1|//C3a anaphylatoxin chemotactic receptor [Rattus norvegicus]"]
[null,84032,4792,1116.27308778459,3572.63192683319,-1.67829727200899,"DOWN",{"v":1.81078630045373e-06,"d":"1.81E-06"},"Col3a1","GO:0005583//fibrillar collagen trimer","GO:0005198//structural molecule activity;GO:0019838//growth factor binding;GO:0005102//receptor binding","GO:0009611//response to wounding;GO:0002683//negative regulation of immune system process;GO:0031589//cell-substrate adhesion;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0009628//response to abiotic stimulus;GO:0008544//epidermis development;GO:0001944//vasculature development;GO:0006464//cellular protein modification process;GO:0030198//extracellular matrix organization;GO:0010033//response to organic substance;GO:0009059//macromolecule biosynthetic process","K19720//collagen, type III, alpha","gi|537234259|gb|ERE84831.1|//collagen alpha-1(III) chain-like isoform 2 [Cricetulus griseus]"]
[null,84357,3154,23.2800557095661,49.0094747507107,-1.07396617438972,"DOWN",0.0396540592229637,"Sh3kbp1","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0043232//intracellular non-membrane-bounded organelle;GO:0043005//neuron projection;GO:0012506//vesicle membrane;GO:0031981//nuclear lumen;GO:0030139//endocytic vesicle;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0045202//synapse;GO:0030659//cytoplasmic vesicle membrane","GO:0019904//protein domain specific binding;GO:0017124//SH3 domain binding;GO:0016772//transferase activity, transferring phosphorus-containing groups","GO:0016477//cell migration;GO:0007154//cell communication;GO:0008360//regulation of cell shape;GO:0006915//apoptotic process;GO:0016192//vesicle-mediated transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0042981//regulation of apoptotic process;GO:0006796//phosphate-containing compound metabolic process","K12470//SH3 domain-containing kinase-binding protein 1","gi|29789297|ref|NP_445812.1|//SH3 domain-containing kinase-binding protein 1 [Rattus norvegicus];gi|672087440|ref|XP_006256991.2|//PREDICTED: SH3 domain-containing kinase-binding protein 1 isoform X3 [Rattus norvegicus]"]
[null,84398,4779,131.374918388913,295.600474266355,-1.16995871619529,"DOWN",0.0462627768871202,"Cd93","GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle","GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0001846//opsonin binding;GO:0004871//signal transducer activity","GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0023052//signaling;GO:0002274//myeloid leukocyte activation","K06702//CDW93 antigen","gi|16758114|ref|NP_445835.1|//complement component C1q receptor precursor [Rattus norvegicus]"]
[null,84407,5173,10.5082422442261,30.5029695871393,-1.5374283375919,"DOWN",0.0177210757320984,"Cdh11","GO:0031224//intrinsic component of membrane;GO:0044424//intracellular part","GO:0046872//metal ion binding","GO:0016337//single organismal cell-cell adhesion","K06803//cadherin 11, type 2, OB-cadherin","gi|281427192|ref|NP_445844.1|//cadherin-11 [Rattus norvegicus] "]
[null,84426,1211,17.1676003209263,45.7883746029107,-1.41529295888831,"DOWN",0.0300395364279648,"Wnt4","GO:0031012//extracellular matrix;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle","GO:0001664//G-protein coupled receptor binding;GO:0060089//molecular transducer activity;GO:0003712//transcription cofactor activity;GO:0005198//structural molecule activity","GO:2000181//negative regulation of blood vessel morphogenesis;GO:0032342//aldosterone biosynthetic process;GO:0033554//cellular response to stress;GO:0030178//negative regulation of Wnt signaling pathway;GO:0003002//regionalization;GO:0033077//T cell differentiation in thymus;GO:0008584//male gonad development;GO:0031948//positive regulation of glucocorticoid biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0071363//cellular response to growth factor stimulus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035567//non-canonical Wnt signaling pathway;GO:0030282//bone mineralization;GO:0072075//metanephric mesenchyme development;GO:0072659//protein localization to plasma membrane;GO:0016337//single organismal cell-cell adhesion;GO:0003338//metanephros morphogenesis;GO:0003382//epithelial cell morphogenesis;GO:0040020//regulation of meiotic nuclear division;GO:0006915//apoptotic process;GO:0035270//endocrine system development;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0061370//testosterone biosynthetic process;GO:0007281//germ cell development;GO:0042692//muscle cell differentiation;GO:0006497//protein lipidation;GO:0016331//morphogenesis of embryonic epithelium;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0031128//developmental induction","K00408//wingless-type MMTV integration site family, member 4","gi|16758130|ref|NP_445854.1|//protein Wnt-4 precursor [Rattus norvegicus]"]
[null,84491,2486,380.46984624972,805.720056318145,-1.08249654920568,"DOWN",0.0219401361370349,"Qsox1","GO:0044421//extracellular region part;GO:0031228//intrinsic component of Golgi membrane","GO:0016972//thiol oxidase activity","GO:0006457//protein folding;GO:0019725//cellular homeostasis","K10758//thiol oxidase [EC:1.8.3.2]","gi|16758172|ref|NP_445883.1|//sulfhydryl oxidase 1 isoform B precursor [Rattus norvegicus];gi|158138547|ref|NP_001103368.1|//sulfhydryl oxidase 1 isoform A precursor [Rattus norvegicus]"]
[null,84551,4117,39.1774949535482,124.880597554678,-1.67245228738437,"DOWN",{"v":7.54848784130812e-05,"d":"7.55E-05"},"Slc7a8","GO:0044424//intracellular part;GO:0044459//plasma membrane part;GO:0016021//integral component of membrane","GO:0003823//antigen binding;GO:0008324//cation transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0042221//response to chemical;GO:0006812//cation transport;GO:0055080//cation homeostasis;GO:0019752//carboxylic acid metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0006865//amino acid transport;GO:0002376//immune system process;GO:0007599//hemostasis","K13781//solute carrier family 7 (L-type amino acid transporter), member 8","gi|16758188|ref|NP_445894.1|//large neutral amino acids transporter small subunit 2 [Rattus norvegicus]"]
[null,84575,3380,2113.01068496217,767.882043467728,1.46034344602259,"UP",0.000841636795910312,"Fads1","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane","GO:0005506//iron ion binding;GO:0016215//acyl-CoA desaturase activity","GO:0032502//developmental process;GO:0000038//very long-chain fatty acid metabolic process;GO:0043434//response to peptide hormone;GO:0006091//generation of precursor metabolites and energy;GO:0001676//long-chain fatty acid metabolic process;GO:0034285//response to disaccharide;GO:0006633//fatty acid biosynthetic process;GO:0033273//response to vitamin;GO:0031669//cellular response to nutrient levels;GO:0051234//establishment of localization","K10224//acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]","gi|162287208|ref|NP_445897.2|//fatty acid desaturase 1 [Rattus norvegicus]"]
[null,84586,3720,142.821431812821,342.191507208089,-1.26059146755225,"DOWN",{"v":8.96386880570446e-05,"d":"8.96E-05"},"Fgl2","GO:0005615//extracellular space","GO:0005515//protein binding;GO:0016787//hydrolase activity","GO:0023052//signaling;GO:0022414//reproductive process","K10104//ficolin;K05466//angiopoietin 2","gi|76781462|ref|NP_445907.2|//fibroleukin precursor [Rattus norvegicus]"]
[null,84604,367,2953.63969162968,441.379896674478,2.74240101900077,"UP",{"v":2.75292581900544e-07,"d":"2.75E-07"},"Hamp","GO:0044448//cell cortex part","NA","GO:0006875//cellular metal ion homeostasis;GO:0006952//defense response","NA","gi|16758218|ref|NP_445921.1|//hepcidin precursor [Rattus norvegicus]"]
[null,84607,2540,512.832691829511,1080.16914821465,-1.07469710946282,"DOWN",0.0125314582916701,"Socs2","GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0005131//growth hormone receptor binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005126//cytokine receptor binding","GO:0007595//lactation;GO:0007589//body fluid secretion;GO:0045666//positive regulation of neuron differentiation;GO:0016567//protein ubiquitination;GO:0043627//response to estrogen;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0060396//growth hormone receptor signaling pathway;GO:0032355//response to estradiol;GO:0040015//negative regulation of multicellular organism growth;GO:0045597//positive regulation of cell differentiation;GO:0001558//regulation of cell growth;GO:0046426//negative regulation of JAK-STAT cascade;GO:0007568//aging;GO:0035264//multicellular organism growth;GO:0060749//mammary gland alveolus development;GO:0006469//negative regulation of protein kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0048856//anatomical structure development","K04695//suppressor of cytokine signaling 2","gi|149067130|gb|EDM16863.1|//suppressor of cytokine signaling 2, isoform CRA_b [Rattus norvegicus];gi|149067132|gb|EDM16865.1|//suppressor of cytokine signaling 2, isoform CRA_d [Rattus norvegicus];gi|488509226|ref|XP_004446793.1|//PREDICTED: suppressor of cytokine signaling 2 isoform X1 [Dasypus novemcinctus]"]
[null,85246,6796,6.84789477268201,17.1929634464164,-1.32808579677916,"DOWN",0.0496576667952746,"Gas7","GO:0031252//cell leading edge;GO:0015629//actin cytoskeleton","GO:0003779//actin binding","GO:0008154//actin polymerization or depolymerization;GO:0048858//cell projection morphogenesis;GO:0030154//cell differentiation;GO:0065008//regulation of biological quality;GO:0048731//system development","K18618//growth arrest-specific protein 7","gi|285026446|ref|NP_445936.2|//growth arrest-specific protein 7 [Rattus norvegicus]"]
[null,85247,538,18.1046920302556,48.8897197292422,-1.43316749874404,"DOWN",0.00543641962725227,"S100a6","GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005635//nuclear envelope;GO:0048471//perinuclear region of cytoplasm;GO:0012505//endomembrane system;GO:0001726//ruffle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part","GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0015075//ion transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding;GO:0005523//tropomyosin binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0048306//calcium-dependent protein binding;GO:0022891//substrate-specific transmembrane transporter activity","GO:0034220//ion transmembrane transport;GO:0023052//signaling;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006811//ion transport;GO:0008284//positive regulation of cell proliferation","K21128//protein S100-A9;K17274//calpactin-1 light chain","gi|537264393|gb|ERE90687.1|//EF-HAND 2 containing protein [Cricetulus griseus]"]
[null,85249,2295,1694.48708456303,515.894381212934,1.71570100180425,"UP",0.00432416032875734,"Pex11a","GO:0005779//integral component of peroxisomal membrane;GO:0031231//intrinsic component of peroxisomal membrane;GO:0043234//protein complex","GO:0042803//protein homodimerization activity","GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0007165//signal transduction;GO:0044375//regulation of peroxisome size;GO:0045444//fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0023052//signaling;GO:0016559//peroxisome fission","K13351//peroxin-11A","gi|16758246|ref|NP_445939.1|//peroxisomal membrane protein 11A [Rattus norvegicus];gi|148675102|gb|EDL07049.1|//peroxisomal biogenesis factor 11a, isoform CRA_b, partial [Mus musculus]"]
[null,85250,5893,80.0459927544013,234.714141183595,-1.55200367897777,"DOWN",0.000473473191185194,"Col5a2","GO:0005583//fibrillar collagen trimer;GO:0005588//collagen type V trimer","GO:0005201//extracellular matrix structural constituent;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046332//SMAD binding","GO:0043588//skin development;GO:0030199//collagen fibril organization;GO:0048592//eye morphogenesis;GO:1903225//negative regulation of endodermal cell differentiation;GO:0071230//cellular response to amino acid stimulus;GO:0009887//animal organ morphogenesis;GO:0008544//epidermis development;GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development","K19721//collagen, type V/XI/XXIV/XXVII, alpha","gi|281371499|ref|NP_445940.1|//collagen alpha-2(V) chain precursor [Rattus norvegicus]"]
[null,85254,4169,292.792543271753,629.241692027071,-1.10373545130628,"DOWN",0.00204101060446561,"Slc44a1","GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane","GO:0005275//amine transmembrane transporter activity","GO:0015697//quaternary ammonium group transport","K06515//solute carrier family 44 (choline transporter-like protein), member 1","gi|76563923|ref|NP_445944.2|//choline transporter-like protein 1 isoform 2 [Rattus norvegicus]"]
[null,85255,2028,3351.31516816185,1543.56677913993,1.11845946903556,"UP",0.0425611135552914,"Hacl1","GO:0042579//microbody;GO:0005777//peroxisome","GO:0000287//magnesium ion binding;GO:0019842//vitamin binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0016830//carbon-carbon lyase activity;GO:0046872//metal ion binding;GO:0016829//lyase activity;GO:0005515//protein binding;GO:0030976//thiamine pyrophosphate binding","GO:0001561//fatty acid alpha-oxidation;GO:0009062//fatty acid catabolic process;GO:0051259//protein oligomerization","K12261//2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-]","gi|27436863|ref|NP_445945.1|//2-hydroxyacyl-CoA lyase 1 [Rattus norvegicus];gi|589967612|ref|XP_006996307.1|//PREDICTED: 2-hydroxyacyl-CoA lyase 1 [Peromyscus maniculatus bairdii]"]
[null,85264,4821,194.047203551789,735.912655763623,-1.92312690305071,"DOWN",{"v":1.63475700661594e-09,"d":"1.63E-09"},"Abcg1","GO:0005654//nucleoplasm;GO:0009897//external side of plasma membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0005768//endosome;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0032934//sterol binding;GO:0008565//protein transporter activity;GO:0046982//protein heterodimerization activity;GO:0017127//cholesterol transporter activity;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0015248//sterol transporter activity;GO:0043531//ADP binding;GO:0019534//toxin transporter activity;GO:0032559//adenyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0034041//sterol-transporting ATPase activity;GO:0034437//glycoprotein transporter activity;GO:0005548//phospholipid transporter activity","GO:0034436//glycoprotein transport;GO:0009593//detection of chemical stimulus;GO:0042987//amyloid precursor protein catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:1901998//toxin transport;GO:0055099//response to high density lipoprotein particle;GO:0016125//sterol metabolic process;GO:0015031//protein transport;GO:0055091//phospholipid homeostasis;GO:0033993//response to lipid;GO:0034369//plasma lipoprotein particle remodeling;GO:0055094//response to lipoprotein particle;GO:0010742//macrophage derived foam cell differentiation;GO:0010893//positive regulation of steroid biosynthetic process;GO:0033700//phospholipid efflux;GO:0043691//reverse cholesterol transport;GO:0010888//negative regulation of lipid storage;GO:0010875//positive regulation of cholesterol efflux;GO:0010878//cholesterol storage;GO:0006355//regulation of transcription, DNA-templated;GO:0006516//glycoprotein catabolic process;GO:0010872//regulation of cholesterol esterification;GO:0015914//phospholipid transport;GO:0042632//cholesterol homeostasis;GO:0009207//purine ribonucleoside triphosphate catabolic process;GO:0010874//regulation of cholesterol efflux;GO:0010883//regulation of lipid storage;GO:0006351//transcription, DNA-templated;GO:0055092//sterol homeostasis;GO:0032367//intracellular cholesterol transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0034375//high-density lipoprotein particle remodeling;GO:0045542//positive regulation of cholesterol biosynthetic process","K05679//ATP-binding cassette, subfamily G (WHITE), member 1","gi|149043544|gb|EDL96995.1|//ATP-binding cassette, sub-family G (WHITE), member 1, isoform CRA_a [Rattus norvegicus];gi|16758262|ref|NP_445954.1|//ATP-binding cassette sub-family G member 1 [Rattus norvegicus]"]
[null,85383,1553,35.5376281311726,87.3598101365094,-1.29762232521965,"DOWN",0.0288581724774901,"Nol3","GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm","GO:0005515//protein binding","GO:0006396//RNA processing;GO:0006915//apoptotic process","K12797//caspase recruitment domain-containing protein 6;K05185//gamma-aminobutyric acid receptor subunit epsilon;K09417//heat shock transcription factor 4","gi|149037998|gb|EDL92358.1|//nucleolar protein 3 (apoptosis repressor with CARD domain), isoform CRA_a [Rattus norvegicus];gi|675751875|ref|XP_002761108.3|//PREDICTED: LOW QUALITY PROTEIN: nucleolar protein 3 [Callithrix jacchus]"]
[null,85483,5295,39.8343981881137,84.6297390602711,-1.08714993930408,"DOWN",0.0394539432211397,"Ciita","GO:0043231//intracellular membrane-bounded organelle","GO:0032559//adenyl ribonucleotide binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006952//defense response;GO:0034097//response to cytokine","K08060//class II, major histocompatibility complex, transactivator","gi|399154121|ref|NP_001257732.1|//MHC class II transactivator isoform 2 [Rattus norvegicus];gi|399154119|ref|NP_445981.2|//MHC class II transactivator isoform 1 [Rattus norvegicus]"]
[null,89783,2170,276.468167610566,591.373283260196,-1.09695568871434,"DOWN",0.00185646454842756,"Laptm5","GO:0016021//integral component of membrane;GO:0005764//lysosome","NA","GO:0051234//establishment of localization","K12387//lysosomal-associated transmembrane protein","gi|40254749|ref|NP_445990.2|//lysosomal-associated transmembrane protein 5 [Rattus norvegicus]"]
[null,89784,2817,908.500736500727,309.189762395635,1.5549951331449,"UP",0.0152016712681554,"Idi1","GO:0042579//microbody","GO:0043169//cation binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds","GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0016109//tetraterpenoid biosynthetic process","K01823//isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]","gi|399567836|ref|NP_445991.2|//isopentenyl-diphosphate Delta-isomerase 1 [Rattus norvegicus]"]
[null,89786,440,785.000410608111,376.999271353675,1.05813167350715,"UP",0.00540662438573654,"Cox17","GO:0005740//mitochondrial envelope","GO:0005507//copper ion binding","GO:0000041//transition metal ion transport;GO:0048513//animal organ development;GO:0044237//cellular metabolic process;GO:0007417//central nervous system development","K02260//cytochrome c oxidase assembly protein subunit 17","gi|744568968|ref|XP_010979873.1|//PREDICTED: cytochrome c oxidase copper chaperone [Camelus dromedarius]"]
[null,89804,4559,133.699699128744,276.356326013212,-1.04753341848726,"DOWN",0.00495743006253678,"Tek","GO:0042995//cell projection;GO:0044459//plasma membrane part;GO:0016021//integral component of membrane","GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding;GO:0004871//signal transducer activity","GO:0016477//cell migration;GO:0006950//response to stress;GO:0001503//ossification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0033189//response to vitamin A;GO:0048534//hematopoietic or lymphoid organ development;GO:0030155//regulation of cell adhesion;GO:0030154//cell differentiation;GO:0031589//cell-substrate adhesion;GO:0043066//negative regulation of apoptotic process;GO:0048545//response to steroid hormone;GO:0009887//animal organ morphogenesis;GO:0045765//regulation of angiogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0006461//protein complex assembly","K05121//endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]","gi|157787147|ref|NP_001099207.1|//angiopoietin-1 receptor [Rattus norvegicus]"]
[null,89806,3844,273.813122256753,648.514331104785,-1.24394686786424,"DOWN",0.000566036792727595,"Tie1","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0032559//adenyl ribonucleotide binding;GO:0004871//signal transducer activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0001701//in utero embryonic development;GO:0030336//negative regulation of cell migration;GO:0043009//chordate embryonic development;GO:0032526//response to retinoic acid;GO:0006464//cellular protein modification process;GO:0045026//plasma membrane fusion;GO:0033189//response to vitamin A;GO:0001570//vasculogenesis;GO:0018108//peptidyl-tyrosine phosphorylation","K05120//tyrosine kinase receptor 1 [EC:2.7.10.1]","gi|197927244|ref|NP_445997.1|//tyrosine-protein kinase receptor Tie-1 precursor [Rattus norvegicus];gi|564352468|ref|XP_006238782.1|//PREDICTED: tyrosine-protein kinase receptor Tie-1 isoform X1 [Rattus norvegicus]"]
[null,94199,1580,14.0182841848699,38.4808625067405,-1.45683135927939,"DOWN",0.0137837013257324,"Dpep1","GO:0031224//intrinsic component of membrane;GO:0044459//plasma membrane part;GO:0005902//microvillus","GO:0043169//cation binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity","GO:0019538//protein metabolic process","K01273//membrane dipeptidase [EC:3.4.13.19]","gi|16758372|ref|NP_446043.1|//dipeptidase 1 precursor [Rattus norvegicus]"]
[null,113882,2512,6.25632963593837,16.679630361882,-1.41469888446025,"DOWN",0.0383047491802842,"Hemgn","GO:0031981//nuclear lumen","NA","GO:0048869//cellular developmental process;GO:0030278//regulation of ossification","K04574//neurofilament heavy polypeptide;K08134//leucine proline-enriched proteoglycan (leprecan)","gi|81884690|sp|Q6AZ54.1|HEMGN_RAT//RecName: Full=Hemogen; AltName: Full=Hemopoietic gene protein; AltName: Full=Protein RP59"]
[null,113902,1940,4951.32980092005,1120.51892635849,2.14364903113622,"UP",0.000147904616362044,"Ces1d","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0044432//endoplasmic reticulum part;GO:0005811//lipid particle;GO:0005829//cytosol","GO:0004806//triglyceride lipase activity;GO:0004771//sterol esterase activity;GO:0030339//fatty-acyl-ethyl-ester synthase activity","GO:0051969//regulation of transmission of nerve impulse;GO:0019626//short-chain fatty acid catabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:0006732//coenzyme metabolic process;GO:0042221//response to chemical;GO:0006637//acyl-CoA metabolic process;GO:0046464//acylglycerol catabolic process;GO:0030855//epithelial cell differentiation;GO:0009636//response to toxic substance","K01044//carboxylesterase 1 [EC:3.1.1.1]","gi|140969642|ref|NP_579829.3|//carboxylesterase 1D precursor [Rattus norvegicus];gi|148679149|gb|EDL11096.1|//mCG145172, partial [Mus musculus]"]
[null,113955,2320,759.807059967992,1637.03707037113,-1.10738196931954,"DOWN",0.0319313713004397,"Gpnmb","GO:0016021//integral component of membrane;GO:0048770//pigment granule","GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding","GO:0009987//cellular process;GO:0001503//ossification","K17304//melanocyte protein PMEL","gi|18959234|ref|NP_579832.1|//transmembrane glycoprotein NMB precursor [Rattus norvegicus]"]
[null,113959,1772,46.5340681836438,109.117406762786,-1.22952203985439,"DOWN",0.00460798258111906,"C5ar1","GO:0031224//intrinsic component of membrane","GO:0001848//complement binding;GO:0004942//null;GO:0001847//opsonin receptor activity","GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0042742//defense response to bacterium;GO:0002237//response to molecule of bacterial origin;GO:0001819//positive regulation of cytokine production;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0043523//regulation of neuron apoptotic process;GO:0045765//regulation of angiogenesis","K04010//C5a anaphylatoxin chemotactic receptor","gi|16758418|ref|NP_446071.1|//C5a anaphylatoxin chemotactic receptor 1 [Rattus norvegicus]"]
[null,113992,2348,2294.29817051111,654.645098188428,1.8092680009081,"UP",0.00256268115749551,"Ugt1a6","GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane","GO:0008194//UDP-glycosyltransferase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005501//retinoid binding","GO:0018879//biphenyl metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0051384//response to glucocorticoid;GO:0006063//uronic acid metabolic process","K00699//glucuronosyltransferase [EC:2.4.1.17]","gi|89276778|ref|NP_001034780.1|//UDP-glucuronosyltransferase 1-6 precursor [Rattus norvegicus]"]
[null,114024,3065,463.647843662141,121.893334373783,1.927410209585,"UP",0.000376658965244646,"Acsl3","GO:0005783//endoplasmic reticulum;GO:0044439//peroxisomal part;GO:0005741//mitochondrial outer membrane;GO:0048471//perinuclear region of cytoplasm;GO:0031224//intrinsic component of membrane;GO:0005811//lipid particle;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005778//peroxisomal membrane","GO:0015645//fatty acid ligase activity;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0032559//adenyl ribonucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0102391//decanoate--CoA ligase activity;GO:0016405//CoA-ligase activity;GO:0019901//protein kinase binding","GO:0014070//response to organic cyclic compound;GO:0006641//triglyceride metabolic process;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0001676//long-chain fatty acid metabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:2001247//positive regulation of phosphatidylcholine biosynthetic process;GO:0010033//response to organic substance;GO:0031667//response to nutrient levels;GO:0006631//fatty acid metabolic process;GO:0007584//response to nutrient;GO:0006633//fatty acid biosynthetic process;GO:0051047//positive regulation of secretion;GO:0044539//long-chain fatty acid import","K01897//long-chain acyl-CoA synthetase [EC:6.2.1.3]","gi|655829623|ref|XP_008257455.1|//PREDICTED: long-chain-fatty-acid--CoA ligase 3 isoform X1 [Oryctolagus cuniculus];gi|149016230|gb|EDL75476.1|//acyl-CoA synthetase long-chain family member 3, isoform CRA_b [Rattus norvegicus];gi|16923952|ref|NP_476448.1|//long-chain-fatty-acid--CoA ligase 3 [Rattus norvegicus]"]
[null,114108,1455,4.46741542115037,13.4053349543577,-1.58529494690772,"DOWN",0.0203217218093968,"Pdlim3","GO:0005856//cytoskeleton;GO:0031674//I band","GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity","GO:0014706//striated muscle tissue development;GO:0030036//actin cytoskeleton organization;GO:0048513//animal organ development","K19867//LIM domain-binding protein 3","gi|25742666|ref|NP_446102.1|//PDZ and LIM domain protein 3 [Rattus norvegicus];gi|51858557|gb|AAH81703.1|//Pdlim3 protein [Rattus norvegicus]"]
[null,114203,2856,45.7941367848566,100.11574273529,-1.12843404813278,"DOWN",0.00520069663861035,"Sh2b2","GO:0031252//cell leading edge;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0001726//ruffle;GO:0001725//stress fiber;GO:0032432//actin filament bundle;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0060089//molecular transducer activity;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity","GO:0007399//nervous system development;GO:0008286//insulin receptor signaling pathway;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0048731//system development;GO:0042593//glucose homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001922//B-1 B cell homeostasis;GO:0046578//regulation of Ras protein signal transduction;GO:0008152//metabolic process;GO:0030036//actin cytoskeleton organization;GO:0046325//negative regulation of glucose import;GO:0019222//regulation of metabolic process;GO:0009967//positive regulation of signal transduction;GO:0045444//fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0007010//cytoskeleton organization;GO:0019221//cytokine-mediated signaling pathway;GO:0001782//B cell homeostasis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0050851//antigen receptor-mediated signaling pathway","K07193//SH2B adapter protein 2","gi|148687368|gb|EDL19315.1|//SH2B adaptor protein 2, isoform CRA_c, partial [Mus musculus];gi|564378780|ref|XP_006249154.1|//PREDICTED: SH2B adapter protein 2 isoform X2 [Rattus norvegicus]"]
[null,114511,1423,46.7986388669719,133.931016491851,-1.51695163180797,"DOWN",0.0031204753615444,"Emb","GO:0031224//intrinsic component of membrane;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045202//synapse","GO:0005515//protein binding","GO:0007155//cell adhesion;GO:0009987//cellular process;GO:0035879//plasma membrane lactate transport","K06535//basigin","gi|16758534|ref|NP_446171.1|//embigin precursor [Rattus norvegicus]"]
[null,114553,2800,116.601588135243,259.681255649527,-1.15515444250347,"DOWN",0.000924541917643898,"Ncf1","GO:0005783//endoplasmic reticulum;GO:0044297//cell body;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection","GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0019904//protein domain specific binding;GO:0005543//phospholipid binding","GO:0006801//superoxide metabolic process;GO:0006605//protein targeting;GO:0009620//response to fungus;GO:0042743//hydrogen peroxide metabolic process;GO:0070944//neutrophil mediated killing of bacterium;GO:0006940//regulation of smooth muscle contraction;GO:0012501//programmed cell death;GO:0006690//icosanoid metabolic process","K08011//neutrophil cytosolic factor 1","gi|40254742|ref|NP_446186.2|//neutrophil cytosolic factor 1 [Rattus norvegicus]"]
[null,114860,1483,484.013618479765,213.397762371525,1.18150259200094,"UP",0.00596318360603744,"Gale","GO:0070062//extracellular exosome","GO:0042802//identical protein binding;GO:0003974//UDP-N-acetylglucosamine 4-epimerase activity;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0048037//cofactor binding;GO:0042803//protein homodimerization activity;GO:0003978//UDP-glucose 4-epimerase activity","GO:0033499//galactose catabolic process via UDP-galactose;GO:0019388//galactose catabolic process;GO:0006012//galactose metabolic process;GO:0061623//glycolytic process from galactose","K01784//UDP-glucose 4-epimerase [EC:5.1.3.2]","gi|672054325|ref|XP_008762419.1|//PREDICTED: UDP-glucose 4-epimerase isoform X2 [Rattus norvegicus]"]
[null,116465,2826,453.278351793572,954.465691376917,-1.07429607942898,"DOWN",{"v":7.95745736850096e-07,"d":"7.96E-07"},"Ifngr1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0044430//cytoskeletal part;GO:0014069//postsynaptic density;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005515//protein binding;GO:0004896//cytokine receptor activity;GO:0004871//signal transducer activity;GO:0042015//interleukin-20 binding","GO:0023052//signaling;GO:0051607//defense response to virus;GO:0019221//cytokine-mediated signaling pathway","K05132//interferon gamma receptor 1","gi|149039622|gb|EDL93784.1|//interferon gamma receptor 1 [Rattus norvegicus]"]
[null,116491,1898,3.65282102670794,16.7005616125631,-2.19281364460182,"DOWN",0.00180376635493412,"Kcnk6","GO:0031224//intrinsic component of membrane","GO:0005261//cation channel activity","GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport","K04917//potassium channel subfamily K member 6","gi|158138511|ref|NP_446258.2|//potassium channel, subfamily K, member 6 [Rattus norvegicus]"]
[null,116548,6607,70.0826014014807,189.681629775671,-1.4364517313042,"DOWN",0.000172668854683853,"Pcsk5","GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part;GO:0016023//null;GO:0044431//Golgi apparatus part","GO:0004175//endopeptidase activity;GO:0005488//binding","GO:0035295//tube development;GO:0048513//animal organ development;GO:0006518//peptide metabolic process;GO:0035107//appendage morphogenesis;GO:0003002//regionalization;GO:0007154//cell communication;GO:0048565//digestive tract development;GO:0001816//cytokine production;GO:0019058//viral life cycle;GO:0016486//peptide hormone processing;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001999//renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure;GO:0001501//skeletal system development","K08654//proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]","gi|353526321|sp|P41413.3|PCSK5_RAT//RecName: Full=Proprotein convertase subtilisin/kexin type 5; AltName: Full=Proprotein convertase 5; Short=PC5; AltName: Full=Proprotein convertase 6; Short=PC6; AltName: Full=Subtilisin/kexin-like protease PC5; Short=rPC5; Flags: Precursor;gi|457866801|ref|NP_446275.1|//proprotein convertase subtilisin/kexin type 5 preproprotein [Rattus norvegicus]"]
[null,116657,3972,26.364616570832,57.2817006243928,-1.11947130981989,"DOWN",0.0459106588195263,"Cplx2","GO:0044424//intracellular part;GO:0044297//cell body;GO:0043234//protein complex;GO:0043005//neuron projection","GO:0019905//syntaxin binding","GO:0006836//neurotransmitter transport;GO:0006887//exocytosis","K15294//complexin-1/2","gi|927191125|ref|XP_013929381.1|//PREDICTED: complexin-2 [Thamnophis sirtalis];gi|507621648|ref|XP_004696860.1|//PREDICTED: complexin-2 [Echinops telfairi]"]
[null,116669,8803,195.760679558411,594.055231480973,-1.60150605520849,"DOWN",0.000164438286312939,"Vwf","GO:0031012//extracellular matrix;GO:0030141//secretory granule;GO:0009986//cell surface","GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0032403//protein complex binding","GO:0007155//cell adhesion;GO:0001775//cell activation;GO:0048513//animal organ development;GO:0007599//hemostasis;GO:0051259//protein oligomerization","K03900//von Willebrand factor","gi|449083357|ref|NP_446341.1|//von Willebrand factor precursor [Rattus norvegicus]"]
[null,116682,1764,1463.11363298608,723.376687013842,1.01622281232493,"UP",0.000321841386028531,"Kynu","GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part","GO:0016823//hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances;GO:0042802//identical protein binding;GO:0048037//cofactor binding","GO:0043650//dicarboxylic acid biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0006084//acetyl-CoA metabolic process;GO:0034097//response to cytokine;GO:0006569//tryptophan catabolic process;GO:0033273//response to vitamin","K01556//kynureninase [EC:3.7.1.3]","gi|16758776|ref|NP_446354.1|//kynureninase [Rattus norvegicus]"]
[null,116724,4438,12.4344793707064,41.3035202662275,-1.73191864318585,"DOWN",0.000834872705569756,"Epb41l3","GO:0005856//cytoskeleton;GO:0043232//intracellular non-membrane-bounded organelle;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0030673//axolemma;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0033270//paranode region of axon;GO:0005911//cell-cell junction;GO:0033267//axon part;GO:0044224//juxtaparanode region of axon","GO:0003779//actin binding;GO:0005198//structural molecule activity","GO:0001558//regulation of cell growth;GO:0030036//actin cytoskeleton organization;GO:0072659//protein localization to plasma membrane;GO:0030866//cortical actin cytoskeleton organization;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0071205//protein localization to juxtaparanode region of axon;GO:0008360//regulation of cell shape;GO:0002175//protein localization to paranode region of axon;GO:0048812//neuron projection morphogenesis;GO:0043217//myelin maintenance;GO:0030913//paranodal junction assembly","K06107//erythrocyte membrane protein band 4.1","gi|16758808|ref|NP_446379.1|//band 4.1-like protein 3 [Rattus norvegicus]"]
[null,117022,879,12.1008179247723,39.4942590583637,-1.70653839013997,"DOWN",0.0124217866733969,"Il1r2","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004910//interleukin-1, Type II, blocking receptor activity;GO:0004908//interleukin-1 receptor activity;GO:0019966//interleukin-1 binding","GO:0010955//negative regulation of protein processing;GO:0050712//negative regulation of interleukin-1 alpha secretion;GO:0007166//cell surface receptor signaling pathway;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:1900016//negative regulation of cytokine production involved in inflammatory response","K04387//interleukin 1 receptor type II","gi|149046289|gb|EDL99182.1|//interleukin 1 receptor, type II, isoform CRA_a [Rattus norvegicus];gi|149046290|gb|EDL99183.1|//interleukin 1 receptor, type II, isoform CRA_b [Rattus norvegicus]"]
[null,117029,2495,15.8126923290501,40.7741312440875,-1.36657111106889,"DOWN",0.0464534678957804,"Ccr5","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface","GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0004950//chemokine receptor activity","GO:0016477//cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0071888//macrophage apoptotic process;GO:0002237//response to molecule of bacterial origin;GO:0007420//brain development;GO:0019058//viral life cycle;GO:0002376//immune system process;GO:0045597//positive regulation of cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0030308//negative regulation of cell growth;GO:0016337//single organismal cell-cell adhesion;GO:0031349//positive regulation of defense response;GO:0001660//fever generation;GO:0009314//response to radiation;GO:0010467//gene expression;GO:0019048//modulation by virus of host morphology or physiology","K04180//C-C chemokine receptor type 5","gi|51592090|ref|NP_446412.2|//C-C chemokine receptor type 5 [Rattus norvegicus]"]
[null,117042,958,1021.73262715836,473.222167624012,1.11042815097459,"UP",0.0360480194504122,"Rpl6","GO:0030529//intracellular ribonucleoprotein complex;GO:0044444//cytoplasmic part","GO:0005198//structural molecule activity","GO:0006412//translation","K02934//large subunit ribosomal protein L6e","gi|162287391|ref|NP_446423.2|//60S ribosomal protein L6 [Rattus norvegicus]"]
[null,117048,3411,114.894793327623,295.748640147131,-1.3640581140233,"DOWN",0.0390682145678286,"Cdh17","GO:0044459//plasma membrane part;GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0015322//secondary active oligopeptide transmembrane transporter activity","GO:0016337//single organismal cell-cell adhesion;GO:0015833//peptide transport","K06811//cadherin 17, LI cadherin","gi|16758872|ref|NP_446429.1|//cadherin-17 precursor [Rattus norvegicus]"]
[null,117257,3824,2.94197246828064,8.28917832274142,-1.49444535394214,"DOWN",0.0337790358316342,"Gpr176","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity","GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway","K08442//G protein-coupled receptor 176","gi|401709975|ref|NP_001257915.1|//probable G-protein coupled receptor 176 [Rattus norvegicus]"]
[null,117269,5396,13.2174423214,53.8019058131214,-2.02521424689291,"DOWN",0.000409707819894856,"Rps6ka2","GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part","GO:0046872//metal ion binding;GO:0032559//adenyl ribonucleotide binding;GO:0004672//protein kinase activity","GO:0003006//developmental process involved in reproduction;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0002224//toll-like receptor signaling pathway;GO:0007067//mitotic nuclear division","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","gi|281306814|ref|NP_476469.1|//ribosomal protein S6 kinase alpha-2 [Rattus norvegicus]"]
[null,117512,2083,13455.5131502984,38950.992394654,-1.53346267397769,"DOWN",0.000452983830089216,"C9","GO:0005887//integral component of plasma membrane","NA","GO:0012502//induction of programmed cell death;GO:0006956//complement activation;GO:0006952//defense response;GO:0007599//hemostasis;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006915//apoptotic process","K04000//complement component 9","gi|149016494|gb|EDL75712.1|//rCG50972 [Rattus norvegicus]"]
[null,117522,3165,599.544317182593,267.004025042177,1.16700490840186,"UP",0.00893891980468112,"Xpnpep2","GO:0070062//extracellular exosome","GO:0043169//cation binding;GO:0008237//metallopeptidase activity","GO:0019538//protein metabolic process","K14208//Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]","gi|16566671|gb|AAL26562.1|AF428102_1//membrane bound aminopeptidase P [Mus musculus];gi|16924020|ref|NP_476496.1|//xaa-Pro aminopeptidase 2 precursor [Rattus norvegicus]"]
[null,117524,3313,37.1688907605833,142.291075381049,-1.93667763833696,"DOWN",0.000253311981649185,"Ccnf","GO:0043231//intracellular membrane-bounded organelle;GO:0005813//centrosome;GO:0031461//cullin-RING ubiquitin ligase complex","NA","GO:0010639//negative regulation of organelle organization;GO:0048513//animal organ development;GO:0000087//mitotic M phase;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation","K10289//F-box protein 1 (cyclin F)","gi|158261993|ref|NP_001093944.1|//cyclin-F [Rattus norvegicus]"]
[null,117538,3968,86.2759197307486,173.314294357277,-1.00636079437318,"DOWN",0.0276379262435476,"Wipf1","GO:0015629//actin cytoskeleton","GO:0005488//binding","GO:0030029//actin filament-based process","K19475//WAS/WASL-interacting protein","gi|48675858|ref|NP_476540.2|//WAS/WASL-interacting protein family member 1 [Rattus norvegicus]"]
[null,117560,2721,234.289033693861,494.141912773707,-1.07663600143815,"DOWN",0.00651054013949967,"Klf9","GO:0043231//intracellular membrane-bounded organelle","GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding","GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0030518//intracellular steroid hormone receptor signaling pathway","K09208//krueppel-like factor 9/13/14/16","gi|17105368|ref|NP_476559.1|//Krueppel-like factor 9 [Rattus norvegicus]"]
[null,140910,1712,1340.23278440055,614.886357721649,1.12409189977594,"UP",0.0495622872345367,"Msmo1","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding","GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0006631//fatty acid metabolic process","K07750//methylsterol monooxygenase [EC:1.14.13.72]","gi|18266684|ref|NP_543162.1|//methylsterol monooxygenase 1 [Rattus norvegicus]"]
[null,140942,1773,89.4936825929368,189.119443416639,-1.07943994427893,"DOWN",0.00902770005357418,"Ddit4","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0071889//14-3-3 protein binding;GO:0005515//protein binding","GO:0032007//negative regulation of TOR signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006950//response to stress;GO:0009968//negative regulation of signal transduction;GO:0006110//regulation of glycolytic process;GO:0007420//brain development;GO:0032984//macromolecular complex disassembly;GO:0008283//cell proliferation;GO:0043241//protein complex disassembly;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0030182//neuron differentiation;GO:0051607//defense response to virus;GO:1901216//positive regulation of neuron death;GO:0072593//reactive oxygen species metabolic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0071549//cellular response to dexamethasone stimulus;GO:0001666//response to hypoxia;GO:0001764//neuron migration;GO:0012501//programmed cell death;GO:0045820//negative regulation of glycolytic process;GO:0010801//negative regulation of peptidyl-threonine phosphorylation","K08270//DNA-damage-inducible transcript 4","gi|18376839|ref|NP_543182.1|//DNA damage-inducible transcript 4 protein [Rattus norvegicus];gi|524935179|ref|XP_005070906.1|//PREDICTED: DNA damage-inducible transcript 4 protein [Mesocricetus auratus]"]
[null,154516,2264,658.934610236421,296.150290712727,1.15380580330604,"UP",0.0380464923968125,"Ugt1a7c","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane","GO:0008194//UDP-glycosyltransferase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005501//retinoid binding","GO:0019217//regulation of fatty acid metabolic process;GO:0006706//steroid catabolic process;GO:0014070//response to organic cyclic compound;GO:0006464//cellular protein modification process;GO:0009804//coumarin metabolic process;GO:0009812//flavonoid metabolic process","K00699//glucuronosyltransferase [EC:2.4.1.17]","gi|51260641|gb|AAH78732.1|//Ugt1a7c protein [Rattus norvegicus]"]
[null,155012,4162,10374.8955033739,23018.5605676607,-1.14970081383247,"DOWN",0.00422694380171872,"Cfh","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0005634//nucleus;GO:0072562//blood microparticle;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0043395//heparan sulfate proteoglycan binding;GO:0001851//complement component C3b binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0001846//opsonin binding","GO:0071346//cellular response to interferon-gamma;GO:0002673//regulation of acute inflammatory response;GO:0006956//complement activation;GO:0030449//regulation of complement activation;GO:0034341//response to interferon-gamma;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0070301//cellular response to hydrogen peroxide","K04004//complement factor H","gi|77861917|ref|NP_569093.2|//complement factor H precursor [Rattus norvegicus];gi|672074006|ref|XP_008767755.1|//PREDICTED: complement factor H isoform X3 [Rattus norvegicus]"]
[null,155918,3407,80.0813955941546,168.768567541563,-1.07550721135295,"DOWN",0.0128249793627317,"Lcp2","GO:0044444//cytoplasmic part","GO:0005488//binding","GO:0009306//protein secretion;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007599//hemostasis;GO:0050851//antigen receptor-mediated signaling pathway;GO:0002274//myeloid leukocyte activation","K07361//lymphocyte cytosolic protein 2","gi|18426850|ref|NP_569105.1|//lymphocyte cytosolic protein 2 [Rattus norvegicus]"]
[null,170465,1619,19175.7873009132,9208.73307233361,1.0582112210828,"UP",0.0249727574151691,"Acaa2","GO:0044429//mitochondrial part;GO:0019866//organelle inner membrane","GO:0016408//C-acyltransferase activity","GO:0006732//coenzyme metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0009062//fatty acid catabolic process","K07508//acetyl-CoA acyltransferase 2 [EC:2.3.1.16]","gi|18426866|ref|NP_569117.1|//3-ketoacyl-CoA thiolase, mitochondrial [Rattus norvegicus]"]
[null,170496,902,3570.58843722504,48783.0993546148,-3.77214766350047,"DOWN",{"v":4.63945018300372e-10,"d":"4.64E-10"},"Lcn2","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0044444//cytoplasmic part","GO:0002020//protease binding;GO:0042802//identical protein binding;GO:0005506//iron ion binding;GO:0046914//transition metal ion binding;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity;GO:0036094//small molecule binding","GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0034614//cellular response to reactive oxygen species;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0051260//protein homooligomerization;GO:0071356//cellular response to tumor necrosis factor;GO:0031346//positive regulation of cell projection organization;GO:0055072//iron ion homeostasis;GO:0071347//cellular response to interleukin-1;GO:0070555//response to interleukin-1;GO:0045087//innate immune response;GO:0031669//cellular response to nutrient levels;GO:0070207//protein homotrimerization;GO:0070301//cellular response to hydrogen peroxide;GO:0010046//response to mycotoxin;GO:0015688//iron chelate transport;GO:0042493//response to drug;GO:0030030//cell projection organization;GO:0010628//positive regulation of gene expression;GO:0009635//response to herbicide;GO:0015891//siderophore transport;GO:0006811//ion transport;GO:0006915//apoptotic process;GO:0010467//gene expression;GO:0034612//response to tumor necrosis factor;GO:0031667//response to nutrient levels;GO:0006952//defense response;GO:0009615//response to virus","K21129//lipocalin 2;K01830//prostaglandin-H2 D-isomerase [EC:5.3.99.2]","gi|18543345|ref|NP_570097.1|//neutrophil gelatinase-associated lipocalin precursor [Rattus norvegicus] ;gi|306526224|sp|P30152.2|NGAL_RAT//RecName: Full=Neutrophil gelatinase-associated lipocalin; Short=NGAL; AltName: Full=Alpha-2-microglobulin-related protein; AltName: Full=Alpha-2U globulin-related protein; AltName: Full=Lipocalin-2; AltName: Full=Siderocalin LCN2; AltName: Full=p25; Flags: Precursor"]
[null,170509,1633,156.643011744253,505.317204160137,-1.68970889042671,"DOWN",0.000153394328930706,"Cyp3a62","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0007608//sensory perception of smell;GO:0007565//female pregnancy;GO:0070989//oxidative demethylation;GO:0010043//response to zinc ion;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0010628//positive regulation of gene expression;GO:0043627//response to estrogen;GO:0007606//sensory perception of chemical stimulus;GO:0045471//response to ethanol;GO:0032355//response to estradiol;GO:0042737//drug catabolic process;GO:0009820//alkaloid metabolic process;GO:0071548//response to dexamethasone;GO:0009822//alkaloid catabolic process","K17689//cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-];K07424//cytochrome P450 family 3 subfamily A [EC:1.14.14.1]","gi|66730479|ref|NP_001019403.1|//cytochrome P450, family 3, subfamily a, polypeptide 62 [Rattus norvegicus];gi|354488851|ref|XP_003506579.1|//PREDICTED: cytochrome P450 3A9-like isoform X1 [Cricetulus griseus]"]
[null,170568,2510,768.035266375601,2074.20013848474,-1.43331064300823,"DOWN",0.000571565848160163,"Dmbt1","GO:0031012//extracellular matrix;GO:0030658//transport vesicle membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005615//extracellular space;GO:0030666//endocytic vesicle membrane;GO:0019898//extrinsic component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix;GO:0042589//zymogen granule membrane;GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle;GO:0016021//integral component of membrane","GO:0005044//scavenger receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0035375//zymogen binding;GO:0019899//enzyme binding","GO:0006810//transport;GO:0006950//response to stress;GO:0042246//tissue regeneration;GO:0043627//response to estrogen;GO:0048545//response to steroid hormone;GO:0001833//inner cell mass cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0006898//receptor-mediated endocytosis;GO:0010033//response to organic substance;GO:0015031//protein transport;GO:0001832//blastocyst growth;GO:0030855//epithelial cell differentiation","K13912//deleted in malignant brain tumors 1 protein","gi|672014845|ref|XP_006223754.2|//PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein-like isoform X6, partial [Rattus norvegicus];gi|975347|gb|AAC52248.1|//ebnerin [Rattus norvegicus];gi|46240860|ref|NP_074040.2|//deleted in malignant brain tumors 1 protein precursor [Rattus norvegicus]"]
[null,170580,627,916.29114817112,338.896758277173,1.43496024549196,"UP",0.000933022083000268,"Fgf21","NA","GO:0005102//receptor binding","GO:0008283//cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010828//positive regulation of glucose transport","K04358//fibroblast growth factor","gi|18543365|ref|NP_570108.1|//fibroblast growth factor 21 precursor [Rattus norvegicus]"]
[null,170583,756,9.07626263543533,79.6875047507517,-3.13418326157077,"DOWN",{"v":1.70720959179898e-06,"d":"1.71E-06"},"Fgf23","GO:0044421//extracellular region part","GO:0005104//fibroblast growth factor receptor binding","GO:0006775//fat-soluble vitamin metabolic process;GO:0010979//regulation of vitamin D 24-hydroxylase activity;GO:0046883//regulation of hormone secretion;GO:0006793//phosphorus metabolic process;GO:0072502//cellular trivalent inorganic anion homeostasis;GO:0006706//steroid catabolic process;GO:0006817//phosphate ion transport;GO:0030279//negative regulation of ossification;GO:0043410//positive regulation of MAPK cascade;GO:0045596//negative regulation of cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway","K04358//fibroblast growth factor","gi|18543369|ref|NP_570110.1|//fibroblast growth factor 23 precursor [Rattus norvegicus]"]
[null,170816,3592,153.039499339035,43.3632473601598,1.81935935359303,"UP",0.0017795388247408,"Olr59","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","GO:0023052//signaling;GO:0007606//sensory perception of chemical stimulus","K04257//olfactory receptor","gi|27545364|ref|NP_775415.1|//olfactory receptor 51E2 [Rattus norvegicus];gi|655601036|ref|XP_008256922.1|//PREDICTED: olfactory receptor 51E2 isoform X1 [Oryctolagus cuniculus]"]
[null,171064,2243,61.2136836911351,131.963354121177,-1.10821125879473,"DOWN",0.0171759802978246,"Igsf6","GO:0031224//intrinsic component of membrane","NA","NA","NA","gi|19424206|ref|NP_598226.1|//immunoglobulin superfamily member 6 precursor [Rattus norvegicus]"]
[null,171081,4095,326.809727715599,791.911842740445,-1.27688890852657,"DOWN",0.000345154862658586,"Csf2rb","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0005488//binding","GO:0001558//regulation of cell growth;GO:0007166//cell surface receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0019221//cytokine-mediated signaling pathway;GO:0002237//response to molecule of bacterial origin","K04738//cytokine receptor common subunit beta","gi|149066007|gb|EDM15880.1|//rCG59972 [Rattus norvegicus];gi|19424232|ref|NP_598239.1|//cytokine receptor common subunit beta precursor [Rattus norvegicus]"]
[null,171099,3469,3.86587222098636,25.9106008478758,-2.74467661302424,"DOWN",0.000100140804966408,"Rasd2","GO:0016020//membrane","GO:0032561//guanyl ribonucleotide binding;GO:0019900//kinase binding;GO:0017111//nucleoside-triphosphatase activity","GO:0007610//behavior;GO:0016925//protein sumoylation;GO:0016567//protein ubiquitination;GO:0007270//neuron-neuron synaptic transmission;GO:0009207//purine ribonucleoside triphosphate catabolic process","K07844//RASD family, member 2","gi|537193698|gb|ERE77608.1|//GTP-binding protein Rhes-like protein [Cricetulus griseus]"]
[null,171103,3132,29.173049861507,77.795086542488,-1.41504282001331,"DOWN",0.00481540013188089,"Cdc25b","GO:0031981//nuclear lumen;GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0044444//cytoplasmic part;GO:0005737//cytoplasm","GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0019901//protein kinase binding","GO:0032467//positive regulation of cytokinesis;GO:0007127//meiosis I;GO:0003006//developmental process involved in reproduction;GO:0000087//mitotic M phase;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045931//positive regulation of mitotic cell cycle;GO:0001556//oocyte maturation;GO:0007067//mitotic nuclear division;GO:0007144//female meiosis I;GO:0008283//cell proliferation;GO:0033674//positive regulation of kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0006470//protein dephosphorylation","K05866//M-phase inducer phosphatase 2 [EC:3.1.3.48]","gi|19424260|ref|NP_598256.1|//M-phase inducer phosphatase 2 [Rattus norvegicus];gi|149023335|gb|EDL80229.1|//cell division cycle 25 homolog B (S. cerevisiae), isoform CRA_a [Rattus norvegicus]"]
[null,171109,3240,214.970921836081,451.537954196625,-1.07070573304297,"DOWN",0.0147434603934763,"Dusp5","GO:0031981//nuclear lumen;GO:0005634//nucleus","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000165//MAPK cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001706//endoderm formation;GO:0001704//formation of primary germ layer;GO:0000188//inactivation of MAPK activity;GO:0035970//peptidyl-threonine dephosphorylation;GO:0006464//cellular protein modification process","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","gi|19424268|ref|NP_598262.1|//dual specificity protein phosphatase 5 [Rattus norvegicus]"]
[null,171139,870,255.775956505371,122.082302785913,1.06702657365345,"UP",0.000429182544694988,"Timm9","GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0019866//organelle inner membrane","GO:0043169//cation binding;GO:0046914//transition metal ion binding","GO:0006612//protein targeting to membrane;GO:0050954//sensory perception of mechanical stimulus","K17777//mitochondrial import inner membrane translocase subunit TIM9","gi|148704607|gb|EDL36554.1|//translocase of inner mitochondrial membrane 9 homolog (yeast), isoform CRA_a, partial [Mus musculus];gi|148704610|gb|EDL36557.1|//translocase of inner mitochondrial membrane 9 homolog (yeast), isoform CRA_b, partial [Mus musculus]"]
[null,171142,3097,17141.6028122294,4903.07724708564,1.8057426175226,"UP",0.00363856843835351,"Ehhadh","GO:0042579//microbody","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016836//hydro-lyase activity;GO:0048037//cofactor binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds","GO:0006732//coenzyme metabolic process;GO:0009062//fatty acid catabolic process","K07514//enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]","gi|295982065|pdb|2X58|A//Chain A, The Crystal Structure Of Mfe1 Liganded With Coa"]
[null,171160,1065,22.3766922448806,54.384974343518,-1.28121132327849,"DOWN",0.0066848923704386,"Hopx","GO:0043231//intracellular membrane-bounded organelle","GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0051149//positive regulation of muscle cell differentiation;GO:0044057//regulation of system process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048513//animal organ development;GO:0043416//regulation of skeletal muscle tissue regeneration;GO:0001825//blastocyst formation;GO:0006476//protein deacetylation","NA","gi|149035176|gb|EDL89880.1|//homeobox only domain, isoform CRA_a [Rattus norvegicus]"]
[null,171385,1011,41.139085280048,113.641556409496,-1.46590887433128,"DOWN",0.0249566558200026,"Acmsd","GO:0044444//cytoplasmic part","GO:0016831//carboxy-lyase activity;GO:0043169//cation binding","GO:0006586//indolalkylamine metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0009820//alkaloid metabolic process","K03392//aminocarboxymuconate-semialdehyde decarboxylase [EC:4.1.1.45]","gi|19705473|ref|NP_599199.1|//2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [Rattus norvegicus]"]
[null,171396,4067,6.80564662660017,20.5729400076464,-1.59594383065243,"DOWN",0.0150744378813766,"Sulf1","GO:0044421//extracellular region part;GO:0044431//Golgi apparatus part","GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity","GO:0048513//animal organ development;GO:0012501//programmed cell death;GO:0008543//fibroblast growth factor receptor signaling pathway","K14607//extracellular sulfatase Sulf [EC:3.1.6.-]","gi|19705485|ref|NP_599205.1|//extracellular sulfatase Sulf-1 precursor [Rattus norvegicus]"]
[null,171548,5010,21.6572483381516,45.2968957989282,-1.06456223265414,"DOWN",0.0230114151992782,"Dkk3","NA","NA","GO:0032342//aldosterone biosynthetic process;GO:0016055//Wnt signaling pathway;GO:0031947//negative regulation of glucocorticoid biosynthetic process;GO:0035270//endocrine system development","K02165//dickkopf","gi|404312665|ref|NP_612528.2|//dickkopf-related protein 3 precursor [Rattus norvegicus]"]
[null,171553,1936,15.0388709081905,61.0241848228417,-2.02068486214298,"DOWN",0.00020526081677406,"A3galt2","GO:0043231//intracellular membrane-bounded organelle","GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity","GO:0006687//glycosphingolipid metabolic process","K00743//N-acetyllactosaminide 3-alpha-galactosyltransferase [EC:2.4.1.87]","gi|19924055|ref|NP_612533.1|//alpha-1,3-galactosyltransferase 2 [Rattus norvegicus]"]
[null,192181,5646,73.7382963155744,190.822744083744,-1.37174714659373,"DOWN",{"v":5.82116803257108e-05,"d":"5.82E-05"},"Podxl","GO:0031252//cell leading edge;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0005815//microtubule organizing center;GO:0044459//plasma membrane part;GO:0005902//microvillus","GO:0005488//binding","GO:0016477//cell migration;GO:0002376//immune system process;GO:0007162//negative regulation of cell adhesion;GO:0022409//positive regulation of cell-cell adhesion;GO:0035148//tube formation;GO:0030033//microvillus assembly","K06817//podocalyxin-like;K21125//mucin-5AC","gi|20301990|ref|NP_620203.1|//podocalyxin precursor [Rattus norvegicus];gi|880966283|ref|XP_012980993.1|//PREDICTED: podocalyxin [Mesocricetus auratus]"]
[null,192247,4034,285.16871244377,136.893462315778,1.05876215501883,"UP",0.0455493447648086,"Sez6","GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0044459//plasma membrane part;GO:0030054//cell junction;GO:0097440//apical dendrite;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0043198//dendritic shaft;GO:0044424//intracellular part;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane","NA","GO:1900006//positive regulation of dendrite development;GO:0021680//cerebellar Purkinje cell layer development;GO:0090036//regulation of protein kinase C signaling;GO:0008344//adult locomotory behavior;GO:2000171//negative regulation of dendrite development;GO:0060074//synapse maturation;GO:0060079//excitatory postsynaptic potential","K17495//CUB and sushi domain-containing protein;K10362//myosin XVIII","gi|564373361|ref|XP_006247016.1|//PREDICTED: seizure protein 6 homolog isoform X2 [Rattus norvegicus];gi|305682549|ref|NP_001099224.2|//seizure protein 6 homolog precursor [Rattus norvegicus]"]
[null,192262,2908,4389.13177195838,11255.3969173865,-1.3586094447676,"DOWN",{"v":1.79151114488787e-07,"d":"1.79E-07"},"C1s","GO:0031012//extracellular matrix","GO:0004175//endopeptidase activity;GO:0046872//metal ion binding","GO:0030154//cell differentiation;GO:0010033//response to organic substance;GO:0006952//defense response;GO:0019538//protein metabolic process;GO:0002455//humoral immune response mediated by circulating immunoglobulin","K01331//complement component 1, s subcomponent [EC:3.4.21.42]","gi|20302095|ref|NP_620255.1|//complement C1s subcomponent precursor [Rattus norvegicus]"]
[null,192272,2400,4855.31942656174,1539.93062602212,1.65670085334065,"UP",0.00691042045504216,"Acot2","GO:0044429//mitochondrial part","NA","GO:0009991//response to extracellular stimulus;GO:0009719//response to endogenous stimulus;GO:0000038//very long-chain fatty acid metabolic process;GO:0006732//coenzyme metabolic process;GO:0042221//response to chemical;GO:0006950//response to stress","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","gi|48675862|ref|NP_620262.2|//acyl-coenzyme A thioesterase 2, mitochondrial [Rattus norvegicus]"]
[null,192362,5157,33.7968594052666,127.409582803323,-1.91451269599879,"DOWN",0.00133642283554372,"Lamc2","GO:0043256//laminin complex;GO:0044444//cytoplasmic part","GO:0005539//glycosaminoglycan binding","GO:0007044//cell-substrate junction assembly","K06246//laminin, gamma 2","gi|281371494|ref|NP_001094110.1|//laminin subunit gamma-2 precursor [Rattus norvegicus] "]
[null,245982,4739,847.98808883631,140.847490603313,2.58991013999176,"UP",{"v":3.26090990219294e-06,"d":"3.26E-06"},"Coro6","GO:0015629//actin cytoskeleton","GO:0003779//actin binding;GO:0051015//actin filament binding","GO:0030036//actin cytoskeleton organization;GO:0007010//cytoskeleton organization","K13886//coronin-1B/1C/6","gi|767996239|ref|XP_011523688.1|//PREDICTED: coronin-6 isoform X4 [Homo sapiens];gi|148747298|ref|NP_620815.2|//coronin-6 [Rattus norvegicus];gi|564373196|ref|XP_006246951.1|//PREDICTED: coronin-6 isoform X3 [Rattus norvegicus]"]
[null,246208,1874,770.288987496642,1787.79366127782,-1.21470853210387,"DOWN",0.0389343798018485,"Ifi47","NA","NA","GO:0006950//response to stress","K17072//interferon gamma inducible protein 47","gi|672067229|ref|XP_008765884.1|//PREDICTED: interferon gamma inducible protein 47 isoform X2 [Rattus norvegicus]"]
[null,246239,1979,89.5483492995528,185.543479451407,-1.05101855786687,"DOWN",0.00488390954368425,"Slc15a3","GO:0031224//intrinsic component of membrane;GO:0005764//lysosome","GO:0015322//secondary active oligopeptide transmembrane transporter activity;GO:0015295//solute:proton symporter activity","GO:0015833//peptide transport;GO:0006811//ion transport;GO:0006818//hydrogen transport;GO:0009057//macromolecule catabolic process","K14638//solute carrier family 15 (peptide/histidine transporter), member 3/4","gi|21326469|ref|NP_647557.1|//solute carrier family 15 member 3 [Rattus norvegicus]"]
[null,246324,3335,55.2298207935124,140.957541695628,-1.35174131758242,"DOWN",0.00271000206638617,"Rab31","GO:0016020//membrane;GO:0005768//endosome;GO:0044431//Golgi apparatus part","GO:0032561//guanyl ribonucleotide binding","GO:0035556//intracellular signal transduction;GO:0016192//vesicle-mediated transport","K07891//Ras-related protein Rab-22","gi|77404176|ref|NP_659562.2|//ras-related protein Rab-31 [Rattus norvegicus]"]
[null,246766,2914,57.6307684062138,150.217172150208,-1.38213858387704,"DOWN",0.00147478960916824,"Ggta1","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0047276//N-acetyllactosaminide 3-alpha-galactosyltransferase activity;GO:0035250//UDP-galactosyltransferase activity","GO:0030259//lipid glycosylation;GO:0033580//protein galactosylation at cell surface;GO:0044238//primary metabolic process","K00743//N-acetyllactosaminide 3-alpha-galactosyltransferase [EC:2.4.1.87]","gi|21728400|ref|NP_663707.1|//N-acetyllactosaminide alpha-1,3-galactosyltransferase [Rattus norvegicus]"]
[null,252917,2341,366.401018856674,761.838250615432,-1.05606120984423,"DOWN",0.00391547092860241,"Nr1d1","GO:0031981//nuclear lumen;GO:0000785//chromatin","GO:0043565//sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0048511//rhythmic process;GO:0032846//positive regulation of homeostatic process","K03728//nuclear receptor subfamily 1 group D member 1","gi|164663889|ref|NP_001106893.1|//nuclear receptor subfamily 1 group D member 1 isoform 1 [Rattus norvegicus]"]
[null,252922,4687,43642.8675110082,116749.557817722,-1.41959928509557,"DOWN",{"v":4.01514643569227e-06,"d":"4.02E-06"},"Pzp","GO:0044421//extracellular region part","GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity","NA","K03910//alpha-2-macroglobulin","gi|205384|gb|AAA41591.1|//alpha-1-macroglobulin [Rattus norvegicus];gi|307746876|ref|NP_665722.2|//alpha-1-macroglobulin precursor [Rattus norvegicus]"]
[null,252963,3681,784.98203873912,1888.1632555395,-1.26625196025414,"DOWN",0.00503554015421658,"Il13ra1","GO:0031224//intrinsic component of membrane","GO:0004896//cytokine receptor activity","GO:0030888//regulation of B cell proliferation;GO:0002377//immunoglobulin production;GO:0007166//cell surface receptor signaling pathway","K05076//interleukin 13 receptor alpha-1","gi|62899063|ref|NP_665732.2|//interleukin-13 receptor subunit alpha-1 precursor [Rattus norvegicus]"]
[null,259246,899,1006.48232945281,356.740366406247,1.49637546737442,"UP",0.0295694851965338,"LOC259246","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0044444//cytoplasmic part","GO:0005009//insulin-activated receptor activity;GO:0005549//odorant binding;GO:0005550//pheromone binding;GO:0005215//transporter activity;GO:0036094//small molecule binding","GO:0001659//temperature homeostasis;GO:0031649//heat generation;GO:0051897//positive regulation of protein kinase B signaling;GO:0051055//negative regulation of lipid biosynthetic process;GO:0008286//insulin receptor signaling pathway;GO:0006111//regulation of gluconeogenesis;GO:0045721//negative regulation of gluconeogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006112//energy reserve metabolic process;GO:0070584//mitochondrion morphogenesis;GO:0045333//cellular respiration;GO:0071396//cellular response to lipid;GO:0045834//positive regulation of lipid metabolic process;GO:0006810//transport;GO:0010907//positive regulation of glucose metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033993//response to lipid;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0009890//negative regulation of biosynthetic process;GO:0010883//regulation of lipid storage;GO:0009893//positive regulation of metabolic process;GO:0009060//aerobic respiration;GO:0010628//positive regulation of gene expression;GO:0007005//mitochondrion organization;GO:0033500//carbohydrate homeostasis;GO:0007626//locomotory behavior;GO:0046676//negative regulation of insulin secretion;GO:0045475//locomotor rhythm;GO:0010888//negative regulation of lipid storage","K01830//prostaglandin-H2 D-isomerase [EC:5.3.99.2]","gi|564351244|ref|XP_006238283.1|//PREDICTED: major urinary protein isoform X2 [Rattus norvegicus];gi|672019427|ref|XP_008774198.1|//PREDICTED: major urinary protein isoform X1 [Rattus norvegicus];gi|22219448|ref|NP_671745.1|//alpha-2u globulin PGCL3 precursor [Rattus norvegicus]"]
[null,266714,4162,57.3171888690319,126.508793804066,-1.14219791293328,"DOWN",0.0189673229732133,"Myo7a","GO:0016324//apical plasma membrane;GO:0042470//melanosome;GO:0005829//cytosol;GO:0032420//stereocilium;GO:0031477//myosin VII complex;GO:0048770//pigment granule;GO:0016461//unconventional myosin complex;GO:0045202//synapse;GO:0005765//lysosomal membrane;GO:0044459//plasma membrane part;GO:0001917//photoreceptor inner segment;GO:0032391//photoreceptor connecting cilium;GO:1990435//upper tip-link density;GO:0005764//lysosome;GO:0001750//photoreceptor outer segment;GO:0005902//microvillus;GO:0031513//null","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0042623//ATPase activity, coupled;GO:0043531//ADP binding;GO:0019904//protein domain specific binding;GO:0032559//adenyl ribonucleotide binding;GO:0000146//microfilament motor activity;GO:0005516//calmodulin binding;GO:0030507//spectrin binding;GO:0030898//actin-dependent ATPase activity","GO:0030048//actin filament-based movement;GO:0060088//auditory receptor cell stereocilium organization;GO:0007601//visual perception;GO:0001845//phagolysosome assembly;GO:0050953//sensory perception of light stimulus;GO:0006897//endocytosis;GO:0009207//purine ribonucleoside triphosphate catabolic process;GO:0051648//vesicle localization;GO:0030029//actin filament-based process;GO:0042471//ear morphogenesis;GO:0060122//inner ear receptor stereocilium organization;GO:0006886//intracellular protein transport;GO:0050957//equilibrioception;GO:0006906//vesicle fusion;GO:0048563//post-embryonic animal organ morphogenesis;GO:0051904//pigment granule transport;GO:0007605//sensory perception of sound;GO:0007033//vacuole organization;GO:0050954//sensory perception of mechanical stimulus","K10359//myosin VII","gi|984084203|ref|XP_015332864.1|//PREDICTED: unconventional myosin-VIIa [Marmota marmota marmota];gi|23618899|ref|NP_703203.1|//unconventional myosin-VIIa [Rattus norvegicus];gi|367460066|ref|NP_001243011.1|//unconventional myosin-VIIa isoform 3 [Mus musculus]"]
[null,266730,2663,1973.76641490686,897.641799262204,1.13673950172892,"UP",{"v":3.55172591062193e-05,"d":"3.55E-05"},"Slc17a3","GO:0044459//plasma membrane part;GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044444//cytoplasmic part;GO:0048471//perinuclear region of cytoplasm","GO:0005342//organic acid transmembrane transporter activity;GO:0015143//urate transmembrane transporter activity;GO:0005244//voltage-gated ion channel activity;GO:0008308//voltage-gated anion channel activity;GO:0015562//efflux transmembrane transporter activity;GO:0015238//drug transmembrane transporter activity;GO:0005436//sodium:phosphate symporter activity;GO:0019534//toxin transporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity","GO:0044341//sodium-dependent phosphate transport;GO:0035725//sodium ion transmembrane transport;GO:0015747//urate transport;GO:1903825//organic acid transmembrane transport;GO:0030001//metal ion transport;GO:0043269//regulation of ion transport;GO:0015893//drug transport;GO:0006863//purine nucleobase transport;GO:1901998//toxin transport;GO:0006082//organic acid metabolic process;GO:0035435//phosphate ion transmembrane transport;GO:0015698//inorganic anion transport;GO:1903959//regulation of anion transmembrane transport;GO:0006855//drug transmembrane transport;GO:0046415//urate metabolic process","K12300//MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4","gi|24025621|ref|NP_705886.1|//sodium-dependent phosphate transport protein 4 [Rattus norvegicus];gi|149031587|gb|EDL86554.1|//solute carrier family 17 (sodium phosphate), member 3, isoform CRA_a [Rattus norvegicus]"]
[null,266778,2661,16.1404530323609,6.23494394559649,1.37223257806324,"UP",0.0493004684685577,"Vom2r44","GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0005938//cell cortex;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0004888//transmembrane signaling receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0010033//response to organic substance;GO:0023052//signaling;GO:0019236//response to pheromone","K04613//vomeronasal 2 receptor","gi|149064653|gb|EDM14804.1|//rCG50085 [Rattus norvegicus];gi|153792702|ref|NP_001092968.1|//vomeronasal type-2 receptor 1 [Rattus norvegicus]"]
[null,266998,3424,66.4170269561592,293.004481392083,-2.14129768064866,"DOWN",0.000400953557495984,"Slc13a5","GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0044459//plasma membrane part;GO:0005887//integral component of plasma membrane","GO:0015291//secondary active transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0015137//citrate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity","GO:0035674//tricarboxylic acid transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0015746//citrate transport;GO:0006842//tricarboxylic acid transport;GO:0071422//succinate transmembrane transport;GO:0006814//sodium ion transport;GO:0015744//succinate transport","K14445//solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5","gi|564372546|ref|XP_006246664.1|//PREDICTED: solute carrier family 13 member 5 isoform X1 [Rattus norvegicus]"]
[null,282580,5547,645.748594554152,1459.06700915327,-1.17600163853951,"DOWN",0.00294735295750658,"Stab2","GO:0044424//intracellular part;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0015036//disulfide oxidoreductase activity;GO:0005041//low-density lipoprotein receptor activity;GO:0005044//scavenger receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005539//glycosaminoglycan binding;GO:0005540//hyaluronic acid binding","GO:0010468//regulation of gene expression;GO:0042742//defense response to bacterium;GO:0030193//regulation of blood coagulation;GO:0007155//cell adhesion;GO:0006952//defense response;GO:0006897//endocytosis;GO:0023052//signaling;GO:0048646//anatomical structure formation involved in morphogenesis","K19013//stabilin-2","gi|607357226|gb|EZA51692.1|//Acetylcholine receptor subunit alpha-like protein [Cerapachys biroi];gi|350534944|ref|NP_001233286.1|//stabilin-2 precursor [Rattus norvegicus]"]
[null,282636,1463,965.24814031415,398.970088249446,1.27461928144317,"UP",0.00596957427397471,"Impa2","GO:0044424//intracellular part;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0043169//cation binding;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0042802//identical protein binding;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0042803//protein homodimerization activity","GO:0006021//inositol biosynthetic process;GO:0007165//signal transduction;GO:0046855//inositol phosphate dephosphorylation;GO:0023052//signaling;GO:0019751//polyol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0046854//phosphatidylinositol phosphorylation","K01092//myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]","gi|74181837|dbj|BAE32621.1|//unnamed protein product [Mus musculus];gi|344244612|gb|EGW00716.1|//Inositol monophosphatase 2 [Cricetulus griseus]"]
[null,282843,3170,239.914943681296,531.40859702198,-1.14729854547637,"DOWN",0.00292346769811761,"Sorbs3","GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0043232//intracellular non-membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0005737//cytoplasm","GO:0008092//cytoskeletal protein binding;GO:0008134//transcription factor binding;GO:0017166//vinculin binding","GO:0003012//muscle system process;GO:0031589//cell-substrate adhesion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051496//positive regulation of stress fiber assembly;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0032233//positive regulation of actin filament bundle assembly;GO:0043410//positive regulation of MAPK cascade","K06086//sorbin and SH3 domain containing 1","gi|149049884|gb|EDM02208.1|//sorbin and SH3 domain containing 3, isoform CRA_a [Rattus norvegicus];gi|54114997|ref|NP_001005762.1|//vinexin [Rattus norvegicus]"]
[null,286976,1991,20.8503313856812,53.1790082334666,-1.3507865583892,"DOWN",0.0205301166032004,"Gcnt3","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane","GO:0008375//acetylglucosaminyltransferase activity","GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006486//protein glycosylation;GO:0009887//animal organ morphogenesis;GO:0022600//digestive system process","K09662//N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]","gi|149028853|gb|EDL84194.1|//glucosaminyl (N-acetyl) transferase 3, mucin type, isoform CRA_b [Rattus norvegicus]"]
[null,287167,429,52.534617883133,184.896480405805,-1.81537745205259,"DOWN",0.000234752803634689,"Hba-a1","GO:0043234//protein complex;GO:0015935//small ribosomal subunit","GO:0005506//iron ion binding","GO:0008217//regulation of blood pressure;GO:0042743//hydrogen peroxide metabolic process;GO:0008219//cell death;GO:0043009//chordate embryonic development;GO:0051931//regulation of sensory perception;GO:0000302//response to reactive oxygen species;GO:0048468//cell development;GO:0051259//protein oligomerization;GO:0051234//establishment of localization","K13822//hemoglobin subunit alpha","gi|62078447|ref|NP_001013875.1|//hemoglobin alpha, adult chain 1 [Rattus norvegicus]"]
[null,287382,1542,5.7088506259303,16.5229752044789,-1.53320126926996,"DOWN",0.0230972055563265,"Mfap4","GO:0031012//extracellular matrix","GO:0005515//protein binding","GO:0023052//signaling","K10104//ficolin","gi|149052868|gb|EDM04685.1|//microfibrillar-associated protein 4 [Rattus norvegicus]"]
[null,287532,6262,130.08624009047,301.334724391718,-1.2118985632386,"DOWN",0.00171007572210496,"Slc43a2","GO:0016020//membrane","GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport","K08229//MFS transporter, LAT3 family, solute carrier family 43, member 2","gi|157786650|ref|NP_001099282.1|//large neutral amino acids transporter small subunit 4 [Rattus norvegicus] ;gi|950368689|dbj|BAT46558.1|//solute carrier family 43, member 2 [Tokudaia muenninki]"]
[null,287610,2926,13.7078981871948,35.558212891512,-1.37517543638906,"DOWN",0.0375349965868138,"Lpo","GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005737//cytoplasm","GO:0016209//antioxidant activity;GO:0036393//thiocyanate peroxidase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0005506//iron ion binding","GO:0006979//response to oxidative stress;GO:0008152//metabolic process;GO:0018969//thiocyanate metabolic process;GO:0098869//cellular oxidant detoxification;GO:0006950//response to stress;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0042742//defense response to bacterium;GO:0055114//oxidation-reduction process","K12550//lactoperoxidase [EC:1.11.1.7]","gi|157786856|ref|NP_001099299.1|//lactoperoxidase precursor [Rattus norvegicus] ;gi|16740670|gb|AAH16212.1|//Lactoperoxidase [Mus musculus]"]
[null,287710,1393,40.3526178589404,86.432188299161,-1.0989064172179,"DOWN",0.0279257570370285,"Ptrf","GO:0031981//nuclear lumen;GO:0044459//plasma membrane part","GO:0019843//rRNA binding","GO:0006352//DNA-templated transcription, initiation","K19387//polymerase I and transcript release factor","gi|157786694|ref|NP_001099311.1|//polymerase I and transcript release factor [Rattus norvegicus] "]
[null,287885,1600,116.634292799531,240.775482163793,-1.04569646000806,"DOWN",0.00375125616543178,"Sectm1a","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane","GO:0060089//molecular transducer activity;GO:0005125//cytokine activity;GO:0004871//signal transducer activity","GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction;GO:0006955//immune response","K06457//T-cell surface glycoprotein CD7","gi|564375618|ref|XP_006247947.1|//PREDICTED: secreted and transmembrane 1A isoform X1 [Rattus norvegicus];gi|149055111|gb|EDM06928.1|//rCG33965, isoform CRA_a [Rattus norvegicus]"]
[null,287899,5723,63.415479214446,255.207798228546,-2.00876547447027,"DOWN",{"v":6.34423656616953e-06,"d":"6.34E-06"},"Adamts2","GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix","GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding","GO:0030324//lung development;GO:0043588//skin development;GO:0048232//male gamete generation;GO:0030199//collagen fibril organization;GO:0030323//respiratory tube development;GO:0007283//spermatogenesis;GO:0032963//collagen metabolic process;GO:0008544//epidermis development;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0016485//protein processing;GO:0030574//collagen catabolic process","K08618//a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14]","gi|212549639|ref|NP_001131094.1|//A disintegrin and metalloproteinase with thrombospondin motifs 2 precursor [Rattus norvegicus] ;gi|33563307|ref|NP_783574.1|//A disintegrin and metalloproteinase with thrombospondin motifs 2 preproprotein [Mus musculus]"]
[null,287910,348,91.0323521429968,208.117105102759,-1.19294428135284,"DOWN",0.0100689206024324,"Ccl6","GO:0044421//extracellular region part","GO:0005125//cytokine activity;GO:0048020//CCR chemokine receptor binding","GO:0002376//immune system process;GO:0012501//programmed cell death;GO:0006935//chemotaxis","K05510//C-C motif chemokine 6/9;K05511//C-C motif chemokine 15/23","gi|149053674|gb|EDM05491.1|//rCG32832 [Rattus norvegicus]"]
[null,288001,1519,38481.6771469722,238215.029644124,-2.63002085711801,"DOWN",{"v":3.51233634909353e-07,"d":"3.51E-07"},"Kng1l1","GO:0044421//extracellular region part;GO:0043025//neuronal cell body","GO:0004866//endopeptidase inhibitor activity;GO:0019899//enzyme binding","GO:0010466//negative regulation of peptidase activity;GO:0007596//blood coagulation;GO:0050880//regulation of blood vessel size;GO:0043405//regulation of MAP kinase activity;GO:0002526//acute inflammatory response;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0030162//regulation of proteolysis;GO:0001935//endothelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K03898//kininogen","gi|57526868|ref|NP_001009628.1|//T-kininogen 2 precursor [Rattus norvegicus]"]
[null,288016,2923,44.2970065969055,134.21455416682,-1.59926000923374,"DOWN",{"v":8.6121980211162e-05,"d":"8.61E-05"},"P3h2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005604//basement membrane","GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019842//vitamin binding;GO:0005506//iron ion binding;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0046914//transition metal ion binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0031418//L-ascorbic acid binding","GO:0032963//collagen metabolic process;GO:0019511//peptidyl-proline hydroxylation;GO:0008152//metabolic process;GO:0008283//cell proliferation;GO:0055114//oxidation-reduction process;GO:0008285//negative regulation of cell proliferation","K08134//leucine proline-enriched proteoglycan (leprecan)","gi|71043726|ref|NP_001020798.1|//prolyl 3-hydroxylase 2 precursor [Rattus norvegicus]"]
[null,288176,1181,76.7074682612308,34.2766528022034,1.1621408120923,"UP",0.003705611674295,"Cmss1","NA","GO:0032559//adenyl ribonucleotide binding;GO:0042623//ATPase activity, coupled","GO:0009207//purine ribonucleoside triphosphate catabolic process","K14784//protein CMS1","gi|62078467|ref|NP_001013888.1|//protein CMSS1 [Rattus norvegicus]"]
[null,288333,2426,1980.8357212638,888.767044638043,1.15623200874633,"UP",{"v":4.21845283104793e-07,"d":"4.22E-07"},"Gbe1","GO:0070062//extracellular exosome;GO:0044444//cytoplasmic part","GO:0030246//carbohydrate binding;GO:0043169//cation binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016758//transferase activity, transferring hexosyl groups;GO:0003844//1,4-alpha-glucan branching enzyme activity;GO:0043167//ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds","GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0019318//hexose metabolic process","K00700//1,4-alpha-glucan branching enzyme [EC:2.4.1.18]","gi|59808285|gb|AAH90037.1|//Gbe1 protein, partial [Rattus norvegicus];gi|281332160|ref|NP_001093972.1|//1,4-alpha-glucan-branching enzyme [Rattus norvegicus];gi|149016756|gb|EDL75918.1|//glucan (1,4-alpha-), branching enzyme 1, isoform CRA_a [Rattus norvegicus]"]
[null,288924,1335,238.053826743504,118.511098862862,1.00626564310005,"UP",0.00211166406254629,"Wdr83","GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome","NA","GO:0000398//mRNA splicing, via spliceosome;GO:0000377//RNA splicing, via transesterification reactions with bulged adenosine as nucleophile","K13124//mitogen-activated protein kinase organizer 1","gi|114145762|ref|NP_001041312.1|//WD repeat domain-containing protein 83 [Rattus norvegicus];gi|149037795|gb|EDL92155.1|//similar to RIKEN cDNA 1500041N16, isoform CRA_a [Rattus norvegicus]"]
[null,289076,708,8.05603711969276,24.9355407371278,-1.63006125279957,"DOWN",0.0191609906489569,"Rgs18","GO:0016020//membrane;GO:0044424//intracellular part","GO:0060089//molecular transducer activity;GO:0008047//enzyme activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0043087//regulation of GTPase activity","K16449//regulator of G-protein signaling","gi|114052553|ref|NP_001040549.1|//regulator of G-protein signaling 18 [Rattus norvegicus]"]
[null,289104,3809,898.947510879929,1832.90998579961,-1.02782715184076,"DOWN",0.0300289398522085,"Prg4","NA","NA","NA","K10955//intestinal mucin-2;K06251//vitronectin","gi|728050528|ref|NP_001099432.3|//proteoglycan 4 precursor [Rattus norvegicus];gi|149058425|gb|EDM09582.1|//proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) (predicted) [Rattus norvegicus]"]
[null,289197,660,1060.57942267574,375.996410497021,1.49606186855615,"UP",{"v":7.29720366764547e-05,"d":"7.30E-05"},"Mgst3","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane","GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004364//glutathione transferase activity;GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity","GO:0006691//leukotriene metabolic process;GO:0009719//response to endogenous stimulus;GO:0010243//response to organonitrogen compound;GO:0098869//cellular oxidant detoxification;GO:0002538//arachidonic acid metabolite production involved in inflammatory response","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|300797728|ref|NP_001178523.1|//microsomal glutathione S-transferase 3 [Rattus norvegicus]"]
[null,289211,1414,449.433955774607,930.118138674725,-1.04930484375231,"DOWN",0.0212512876705281,"Fcgr2b","GO:0009986//cell surface;GO:0016021//integral component of membrane","GO:0019865//immunoglobulin binding;GO:0004871//signal transducer activity","GO:0030888//regulation of B cell proliferation;GO:0002683//negative regulation of immune system process;GO:0007165//signal transduction;GO:0045806//negative regulation of endocytosis;GO:0002377//immunoglobulin production;GO:0002237//response to molecule of bacterial origin;GO:0045807//positive regulation of endocytosis;GO:0001818//negative regulation of cytokine production;GO:0002478//antigen processing and presentation of exogenous peptide antigen;GO:0001810//regulation of type I hypersensitivity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006909//phagocytosis;GO:0002274//myeloid leukocyte activation","K16824//low affinity immunoglobulin gamma Fc receptor II-c;K06472//low affinity immunoglobulin gamma Fc receptor II-a;K12560//low affinity immunoglobulin gamma Fc receptor II-b","gi|225384|prf||1301316A//macrophage lymphocyte receptor"]
[null,289235,1125,19.9631370387192,46.5359799802052,-1.2210081427757,"DOWN",0.0132439134186063,"Slamf9","NA","NA","NA","K06570//lymphocyte antigen 9","gi|157787012|ref|NP_001099441.1|//SLAM family member 9 precursor [Rattus norvegicus] "]
[null,289237,1893,30.183600880939,67.8945732058036,-1.16953133630043,"DOWN",0.00569086429123228,"Slamf8","GO:0031224//intrinsic component of membrane;GO:0005623//cell;GO:0016021//integral component of membrane","GO:0004872//receptor activity;GO:0042802//identical protein binding","GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0010760//negative regulation of macrophage chemotaxis;GO:0035690//cellular response to drug;GO:0042742//defense response to bacterium;GO:0090383//phagosome acidification;GO:1902623//negative regulation of neutrophil migration;GO:0090027//negative regulation of monocyte chemotaxis;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0033860//regulation of NAD(P)H oxidase activity;GO:0043549//regulation of kinase activity;GO:2000509//negative regulation of dendritic cell chemotaxis","K16853//SLAM family member 8","gi|157787076|ref|NP_001099443.1|//SLAM family member 8 precursor [Rattus norvegicus] ;gi|564381809|ref|XP_006250346.1|//PREDICTED: SLAM family member 8 isoform X1 [Rattus norvegicus]"]
[null,289388,755,1803.84107510176,778.440040156621,1.21241441337529,"UP",0.00434703056924361,"G0s2","NA","NA","NA","NA","gi|57526884|ref|NP_001009632.1|//G0/G1 switch protein 2 [Rattus norvegicus]"]
[null,289459,2482,36.2515236857765,87.7184845026521,-1.27483925279281,"DOWN",0.0251890117413818,"Slc10a6","GO:0031224//intrinsic component of membrane;GO:0005887//integral component of plasma membrane","GO:0043250//sodium-dependent organic anion transmembrane transporter activity;GO:0005343//organic acid:sodium symporter activity;GO:0008508//bile acid:sodium symporter activity;GO:0008514//organic anion transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0015711//organic anion transport;GO:0015718//monocarboxylic acid transport;GO:0015721//bile acid and bile salt transport;GO:0006814//sodium ion transport;GO:0043251//sodium-dependent organic anion transport","K14346//solute carrier family 10 (sodium/bile acid cotransporter), member 6","gi|568936331|ref|XP_006535341.1|//PREDICTED: solute carrier family 10 member 6 isoform X1 [Mus musculus];gi|37591183|ref|NP_932166.1|//solute carrier family 10 member 6 [Rattus norvegicus]"]
[null,289596,3645,10.0431504112128,27.3863544897514,-1.44724534000332,"DOWN",0.0151266174268113,"Corin","GO:0031224//intrinsic component of membrane","GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0008236//serine-type peptidase activity","GO:0030154//cell differentiation;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0023052//signaling","K09614//corin [EC:3.4.21.-]","gi|32563562|ref|NP_872279.1|//atrial natriuretic peptide-converting enzyme [Rattus norvegicus]"]
[null,289754,1956,1981.19434382926,4130.30075277968,-1.05987642973339,"DOWN",0.000454667755252108,"Xbp1","GO:0043231//intracellular membrane-bounded organelle","GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0001820//serotonin secretion;GO:0042221//response to chemical;GO:0006351//transcription, DNA-templated;GO:0009628//response to abiotic stimulus;GO:0031016//pancreas development;GO:0002376//immune system process;GO:0006984//ER-nucleus signaling pathway;GO:0002070//epithelial cell maturation","K09027//X box-binding protein 1","gi|913512819|ref|XP_013208852.1|//PREDICTED: LOW QUALITY PROTEIN: X-box-binding protein 1 [Microtus ochrogaster];gi|795370319|ref|XP_011749032.1|//PREDICTED: LOW QUALITY PROTEIN: X-box-binding protein 1 [Macaca nemestrina];gi|411147454|ref|NP_001258660.1|//X-box-binding protein 1 isoform XBP1(S) [Rattus norvegicus]"]
[null,290350,2585,29.3609678232704,84.93438636279,-1.53244923421617,"DOWN",0.0127053858613083,"Loxl2","GO:0044464//cell part","GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0046914//transition metal ion binding","GO:0008152//metabolic process","K00280//lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-]","gi|201066363|ref|NP_001099517.2|//lysyl oxidase homolog 2 precursor [Rattus norvegicus]"]
[null,290553,1097,6.29160722926862,32.4960991627942,-2.36876603267256,"DOWN",0.000275050471301797,"Mustn1","NA","NA","GO:0009611//response to wounding;GO:0009888//tissue development;GO:0035108//limb morphogenesis","NA","gi|149034210|gb|EDL88980.1|//musculoskeletal, embryonic nuclear protein 1 [Rattus norvegicus]"]
[null,290686,1043,84.7210340516628,41.3168220083428,1.03599090826604,"UP",0.0308416456120839,"Tma16","GO:0005730//nucleolus","NA","NA","K14860//translation machinery-associated protein 16","gi|281182657|ref|NP_001162573.1|//translation machinery-associated protein 16 [Rattus norvegicus] "]
[null,290905,6579,441.406043798652,1231.72958859181,-1.48050727599482,"DOWN",0.000356842912223502,"Col4a1","NA","NA","NA","K06237//collagen, type IV, alpha","gi|641706489|ref|XP_008142163.1|//PREDICTED: collagen alpha-1(IV) chain [Eptesicus fuscus]"]
[null,290986,4485,32.7690970964184,74.1292749016516,-1.1777074775611,"DOWN",0.0401622868548119,"Agtpbp1","GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part","GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity","GO:0001505//regulation of neurotransmitter levels;GO:0035608//protein deglutamylation;GO:0006996//organelle organization;GO:0021988//olfactory lobe development;GO:0046530//photoreceptor cell differentiation;GO:0021533//cell differentiation in hindbrain;GO:0021695//cerebellar cortex development;GO:0018410//C-terminal protein amino acid modification","K05840//dopamine receptor D5;K04257//olfactory receptor","gi|157820001|ref|NP_001099570.1|//cytosolic carboxypeptidase 1 [Rattus norvegicus] "]
[null,291005,1151,1845.62726325523,817.256077916512,1.17525111406975,"UP",0.0113747983070816,"Gadd45g","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0005515//protein binding;GO:0005488//binding","GO:0046330//positive regulation of JNK cascade;GO:0000165//MAPK cascade;GO:0033673//negative regulation of kinase activity;GO:0032609//interferon-gamma production;GO:0045063//T-helper 1 cell differentiation;GO:0042093//T-helper cell differentiation;GO:0000185//activation of MAPKKK activity;GO:1900745//positive regulation of p38MAPK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0043065//positive regulation of apoptotic process;GO:0042095//interferon-gamma biosynthetic process;GO:0012501//programmed cell death;GO:0051726//regulation of cell cycle;GO:0007049//cell cycle;GO:0000186//activation of MAPKK activity","K04402//growth arrest and DNA-damage-inducible protein","gi|117647202|ref|NP_001071108.1|//growth arrest and DNA damage-inducible protein GADD45 gamma [Rattus norvegicus];gi|533192200|ref|XP_005408930.1|//PREDICTED: growth arrest and DNA damage-inducible protein GADD45 gamma [Chinchilla lanigera]"]
[null,291091,1289,52.562764837895,126.229745264298,-1.2639388430798,"DOWN",0.00169722403922403,"Serpinb1a","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0044424//intracellular part;GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0005737//cytoplasm","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0006508//proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0042176//regulation of protein catabolic process;GO:0009894//regulation of catabolic process","K13963//serpin B","gi|72255515|ref|NP_001026812.1|//leukocyte elastase inhibitor A [Rattus norvegicus]"]
[null,291130,6788,21.7703094705988,58.9263099571674,-1.43655000960575,"DOWN",0.00625982845218729,"Dcdc2","NA","NA","GO:0016477//cell migration;GO:0007165//signal transduction;GO:0006952//defense response;GO:0048731//system development","K16579//neuronal migration protein doublecortin;K08805//doublecortin-like kinase 1/2 [EC:2.7.11.1]","gi|167830444|ref|NP_001099580.2|//doublecortin domain-containing protein 2 [Rattus norvegicus]"]
[null,291327,5233,621.997818099338,1395.61215313654,-1.1659166411787,"DOWN",0.00261874396028815,"Mrc1","GO:0031224//intrinsic component of membrane","GO:0048029//monosaccharide binding;GO:0004872//receptor activity","GO:0023052//signaling;GO:0016192//vesicle-mediated transport","K06560//mannose receptor, C type","gi|149021126|gb|EDL78733.1|//mannose receptor, C type 1 (predicted) [Rattus norvegicus]"]
[null,291530,1307,56.3232074532779,117.712685264788,-1.06346840128048,"DOWN",0.044693444847293,"Ccdc68","GO:0005622//intracellular","NA","GO:0035556//intracellular signal transduction","K20283//golgin subfamily A member 4;K06102//cingulin;K16469//rootletin;K11502//centromere protein J","gi|672083347|ref|XP_008770336.1|//PREDICTED: coiled-coil domain-containing protein 68 isoform X3 [Rattus norvegicus];gi|672083345|ref|XP_008770335.1|//PREDICTED: coiled-coil domain-containing protein 68 isoform X2 [Rattus norvegicus];gi|149064570|gb|EDM14773.1|//similar to CTCL tumor antigen se57-1 (predicted), isoform CRA_b [Rattus norvegicus]"]
[null,291541,915,889.624168605569,273.349387110021,1.702449841787,"UP",{"v":2.05168577855909e-05,"d":"2.05E-05"},"Cidea","GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031967//organelle envelope","GO:0042802//identical protein binding","GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050707//regulation of cytokine secretion;GO:0009895//negative regulation of catabolic process;GO:0001818//negative regulation of cytokine production;GO:0000737//DNA catabolic process, endonucleolytic;GO:0048871//multicellular organismal homeostasis;GO:0010884//positive regulation of lipid storage","K02310//DNA fragmentation factor, 45 kD, alpha subunit;K02311//DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]","gi|281427180|ref|NP_001163938.1|//cell death activator CIDE-A [Rattus norvegicus]"]
[null,291760,4653,1779.46390084243,3739.36362143137,-1.07135010202696,"DOWN",0.000216054487466938,"Dsc2","GO:0070062//extracellular exosome;GO:0031410//cytoplasmic vesicle;GO:0031224//intrinsic component of membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0046872//metal ion binding;GO:0005509//calcium ion binding","GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0016337//single organismal cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:0009267//cellular response to starvation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0086091//regulation of heart rate by cardiac conduction","K07601//desmocollin 2","gi|148664522|gb|EDK96938.1|//desmocollin 2, isoform CRA_a, partial [Mus musculus];gi|76096314|ref|NP_001028860.1|//desmocollin-2 precursor [Rattus norvegicus]"]
[null,291966,1000,5.95865669293274,17.3684085875411,-1.54340653620004,"DOWN",0.0201563555932127,"Tppp3","GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm","GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding","GO:0000226//microtubule cytoskeleton organization;GO:0046785//microtubule polymerization;GO:0001578//microtubule bundle formation","K20027//palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]","gi|537191633|gb|ERE77168.1|//tubulin polymerization-promoting protein family member 3-like protein [Cricetulus griseus];gi|685613849|ref|XP_009194938.1|//PREDICTED: tubulin polymerization-promoting protein family member 3 isoform X1 [Papio anubis]"]
[null,291975,1535,27.5798146797479,11.9444906218303,1.20726743208832,"UP",0.0418817053377803,"Enkd1","GO:0005856//cytoskeleton","NA","NA","K08396//Mas-related G protein-coupled receptor member X","gi|157818461|ref|NP_001099650.1|//enkurin domain-containing protein 1 [Rattus norvegicus] "]
[null,292130,3978,37.0964407178603,77.9487598050565,-1.07124529765279,"DOWN",0.0170593566005963,"Afap1l2","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019904//protein domain specific binding;GO:0030295//protein kinase activator activity;GO:0035591//signaling adaptor activity;GO:0017124//SH3 domain binding;GO:0042169//SH2 domain binding;GO:0030296//protein tyrosine kinase activator activity","GO:0000278//mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0032757//positive regulation of interleukin-8 production;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0001819//positive regulation of cytokine production;GO:0006954//inflammatory response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032675//regulation of interleukin-6 production;GO:0009967//positive regulation of signal transduction;GO:0006952//defense response;GO:0045860//positive regulation of protein kinase activity;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway","K18616//actin filament associated protein 1","gi|762005996|ref|NP_001292113.1|//actin filament-associated protein 1-like 2 [Rattus norvegicus]"]
[null,292401,2718,16.2199495056263,55.1343612322341,-1.76518239754483,"DOWN",0.00353009821074503,"Smoc2","GO:0005578//proteinaceous extracellular matrix","GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding","GO:0023052//signaling;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization","K06826//nidogen (entactin)","gi|157819145|ref|NP_001099685.1|//SPARC-related modular calcium-binding protein 2 precursor [Rattus norvegicus]"]
[null,292406,5728,42.3076855234451,123.445769542363,-1.54488572735345,"DOWN",0.00275972274113735,"Thbs2","GO:0005578//proteinaceous extracellular matrix","GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding","GO:0001525//angiogenesis;GO:0044089//positive regulation of cellular component biogenesis","K04659//thrombospondin 2/3/4/5","gi|281332082|ref|NP_001162609.1|//thrombospondin-2 precursor [Rattus norvegicus]"]
[null,292486,1385,392.630556323007,175.208154709055,1.16410253054016,"UP",0.0421409907344806,"Aig1","GO:0031224//intrinsic component of membrane","NA","NA","NA","gi|197313676|ref|NP_001127897.1|//androgen-induced gene 1 protein [Rattus norvegicus]"]
[null,292543,3062,124.919762539185,52.3767227688929,1.25400403438748,"UP",0.0181157144893414,"LOC292543","GO:0031224//intrinsic component of membrane","GO:0005275//amine transmembrane transporter activity","NA","K13865//solute carrier family 7 (cationic amino acid transporter), member 3","gi|672034411|ref|XP_008756976.1|//PREDICTED: uncharacterized protein LOC292543 isoform X1 [Rattus norvegicus];gi|568945773|ref|XP_006540047.1|//PREDICTED: cationic amino acid transporter 5 isoform X1 [Mus musculus];gi|564325646|ref|XP_006228084.1|//PREDICTED: uncharacterized protein LOC292543 isoform X2 [Rattus norvegicus]"]
[null,292710,967,645.208421887814,298.323809136944,1.11288614673311,"UP",0.000163081966393917,"Ethe1","GO:0044429//mitochondrial part","GO:0043169//cation binding;GO:0003824//catalytic activity","NA","K17725//sulfur dioxygenase [EC:1.13.11.18]","gi|157819563|ref|NP_001099704.1|//persulfide dioxygenase ETHE1, mitochondrial [Rattus norvegicus]"]
[null,292999,3758,54.2060630413352,126.436312459213,-1.2218847308366,"DOWN",0.00158169537210166,"Chsy1","GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane","GO:0043169//cation binding;GO:0015020//glucuronosyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity","GO:0006024//glycosaminoglycan biosynthetic process","K13499//chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226]","gi|157823465|ref|NP_001099738.1|//chondroitin sulfate synthase 1 precursor [Rattus norvegicus] "]
[null,293154,1145,76.3860750636021,278.800358470164,-1.86785084750053,"DOWN",{"v":8.32583444585372e-10,"d":"8.33E-10"},"Folr2","GO:0031224//intrinsic component of membrane;GO:0031362//anchored component of external side of plasma membrane","GO:0005542//folic acid binding;GO:0051870//methotrexate binding;GO:0016597//amino acid binding;GO:0051183//vitamin transporter activity;GO:0008517//folic acid transporter activity;GO:0004871//signal transducer activity","GO:0006612//protein targeting to membrane;GO:0015884//folic acid transport;GO:0023052//signaling;GO:0006620//posttranslational protein targeting to membrane;GO:0008284//positive regulation of cell proliferation","K13649//folate receptor","gi|157820549|ref|NP_001099753.1|//folate receptor beta precursor [Rattus norvegicus] "]
[null,293677,1634,63.4528187434752,198.185578643601,-1.64309582688795,"DOWN",0.00209955482078902,"Efemp2","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0044464//cell part;GO:0005578//proteinaceous extracellular matrix","GO:0046872//metal ion binding;GO:0004872//receptor activity;GO:0005509//calcium ion binding","GO:0023052//signaling;GO:0007599//hemostasis","K19866//EGF-containing fibulin-like extracellular matrix protein 2","gi|54400722|ref|NP_001005907.1|//EGF-containing fibulin-like extracellular matrix protein 2 isoform 2 precursor [Rattus norvegicus];gi|564332150|ref|XP_006230804.1|//PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 isoform X2 [Rattus norvegicus];gi|795501906|ref|XP_011897030.1|//PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 isoform X1 [Cercocebus atys];gi|474451700|ref|NP_001264275.1|//EGF-containing fibulin-like extracellular matrix protein 2 isoform 3 precursor [Rattus norvegicus]"]
[null,293749,1404,79.2335004654069,217.988271050881,-1.46006806655946,"DOWN",0.00173687425283948,"Ms4a6bl","GO:0044464//cell part","GO:0004871//signal transducer activity","GO:0023052//signaling","K08090//membrane-spanning 4-domains, subfamily A, member 2","gi|55741532|ref|NP_001006976.1|//membrane-spanning 4-domains, subfamily A, member 6B-like [Rattus norvegicus]"]
[null,293820,2625,332.307237060412,76.9541528028016,2.11044662442453,"UP",{"v":4.34892688163409e-06,"d":"4.35E-06"},"Psat1","GO:0044424//intracellular part","GO:0008483//transaminase activity;GO:0048037//cofactor binding","GO:0006563//L-serine metabolic process","K00831//phosphoserine aminotransferase [EC:2.6.1.52]","gi|537196554|gb|ERE78403.1|//phosphoserine aminotransferase isoform 1 [Cricetulus griseus];gi|61889115|ref|NP_942033.2|//phosphoserine aminotransferase [Rattus norvegicus]"]
[null,293860,8563,490.359528804257,1052.2714403913,-1.10159508731733,"DOWN",0.00512561623409248,"Flna","GO:0016020//membrane;GO:0005903//brush border;GO:0043025//neuronal cell body;GO:0030863//cortical cytoskeleton;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0032432//actin filament bundle;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0031523//Myb complex;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0097440//apical dendrite;GO:0005802//trans-Golgi network;GO:0044431//Golgi apparatus part;GO:0048471//perinuclear region of cytoplasm;GO:0043198//dendritic shaft;GO:0031941//filamentous actin","GO:0051015//actin filament binding;GO:0017048//Rho GTPase binding;GO:0048365//Rac GTPase binding;GO:0019901//protein kinase binding;GO:0034988//Fc-gamma receptor I complex binding;GO:0004871//signal transducer activity;GO:0017160//Ral GTPase binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0044822//poly(A) RNA binding;GO:0031852//mu-type opioid receptor binding;GO:0060089//molecular transducer activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0034987//immunoglobulin receptor binding;GO:0001948//glycoprotein binding;GO:0046332//SMAD binding;GO:0008134//transcription factor binding","GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042177//negative regulation of protein catabolic process;GO:0007172//signal complex assembly;GO:0045216//cell-cell junction organization;GO:0007015//actin filament organization;GO:0001837//epithelial to mesenchymal transition;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0043066//negative regulation of apoptotic process;GO:0001974//blood vessel remodeling;GO:0043392//negative regulation of DNA binding;GO:0009895//negative regulation of catabolic process;GO:0034394//protein localization to cell surface;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0051220//cytoplasmic sequestering of protein;GO:0045022//early endosome to late endosome transport;GO:0051764//actin crosslink formation;GO:0032507//maintenance of protein location in cell;GO:0032231//regulation of actin filament bundle assembly;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0003007//heart morphogenesis;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0030334//regulation of cell migration;GO:0010977//negative regulation of neuron projection development;GO:0044319//wound healing, spreading of cells;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0016197//endosomal transport;GO:0031532//actin cytoskeleton reorganization;GO:0043113//receptor clustering;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0090307//mitotic spindle assembly;GO:0031647//regulation of protein stability;GO:0016479//negative regulation of transcription from RNA polymerase I promoter;GO:0071526//semaphorin-plexin signaling pathway;GO:0070527//platelet aggregation;GO:0050821//protein stabilization;GO:0042307//positive regulation of protein import into nucleus","K04437//filamin","gi|197386807|ref|NP_001128071.1|//filamin-A [Rattus norvegicus]"]
[null,293862,1334,53.7111181494621,12.6893859278249,2.08159850047334,"UP",0.00285918160270857,"Fam50a","GO:0043231//intracellular membrane-bounded organelle","NA","NA","K13119//protein FAM50","gi|281604125|ref|NP_001164044.1|//protein FAM50A [Rattus norvegicus] "]
[null,294254,5918,320.313949638972,60.5613690629138,2.40301690402944,"UP",{"v":1.42889303835909e-05,"d":"1.43E-05"},"Hspa1b","GO:0032991//macromolecular complex;GO:0044429//mitochondrial part;GO:0044459//plasma membrane part;GO:0016604//nuclear body","GO:0032559//adenyl ribonucleotide binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0006401//RNA catabolic process;GO:0006457//protein folding;GO:0010466//negative regulation of peptidase activity;GO:0019229//regulation of vasoconstriction;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0016049//cell growth;GO:0006259//DNA metabolic process;GO:0008283//cell proliferation;GO:0033028//myeloid cell apoptotic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity","K03283//heat shock 70kDa protein 1/8","gi|47059179|ref|NP_997669.1|//heat shock 70kD protein 1B [Rattus norvegicus]"]
[null,294255,2254,82.7934921869611,182.052063288247,-1.13676181446655,"DOWN",0.00938800342916028,"Slc44a4","GO:0031224//intrinsic component of membrane","NA","NA","K15377//solute carrier family 44 (choline transporter-like protein), member 2/4/5","gi|47087113|ref|NP_997706.1|//choline transporter-like protein 4 [Rattus norvegicus]"]
[null,294269,1212,733.659887429745,1875.24078758785,-1.35389254104206,"DOWN",0.00291735899990765,"RT1-Da","GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0042611//MHC protein complex","NA","GO:0019882//antigen processing and presentation","K06752//major histocompatibility complex, class II","gi|57114292|ref|NP_001008847.1|//RT1 class II, locus Da precursor [Rattus norvegicus]"]
[null,294274,1112,32.3994790019073,9.55634438188275,1.761439863886,"UP",0.010343425928989,"RT1-DMa","GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0005764//lysosome;GO:0042611//MHC protein complex","GO:0005488//binding","GO:0006810//transport;GO:0051084//'de novo' posttranslational protein folding;GO:0045580//regulation of T cell differentiation;GO:0065003//macromolecular complex assembly;GO:0043368//positive T cell selection;GO:0002684//positive regulation of immune system process;GO:0002920//regulation of humoral immune response;GO:0002467//germinal center formation;GO:0002478//antigen processing and presentation of exogenous peptide antigen;GO:0019724//B cell mediated immunity","K06752//major histocompatibility complex, class II","gi|38454220|ref|NP_942036.1|//RT1 class II, DM alpha precursor [Rattus norvegicus]"]
[null,294643,765,101.079837210477,237.332552142847,-1.23141474585397,"DOWN",0.009006257456295,"Lhfpl2","GO:0044464//cell part;GO:0016021//integral component of membrane","NA","NA","NA","gi|157822913|ref|NP_001099872.1|//lipoma HMGIC fusion partner-like 2 protein [Rattus norvegicus] ;gi|149034547|gb|EDL89284.1|//methyl-CpG binding domain protein 3 (predicted), isoform CRA_d [Rattus norvegicus]"]
[null,294706,2566,21.1855985498452,46.0509413734286,-1.12014675892002,"DOWN",0.0406809842629249,"Cd180","GO:0031224//intrinsic component of membrane","GO:0004871//signal transducer activity;GO:0005488//binding","GO:0006952//defense response;GO:0023052//signaling","K06555//CD180 antigen","gi|157823329|ref|NP_001099875.1|//CD180 antigen precursor [Rattus norvegicus] "]
[null,294962,1516,20.1187109058731,42.6340803366573,-1.08346926815937,"DOWN",0.0324240486874501,"Gnb4","GO:0031234//extrinsic component of cytoplasmic side of plasma membrane","GO:0060089//molecular transducer activity;GO:0017111//nucleoside-triphosphatase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0033762//response to glucagon;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007606//sensory perception of chemical stimulus","K04538//guanine nucleotide-binding protein subunit beta-4","gi|62078551|ref|NP_001013932.1|//guanine nucleotide-binding protein subunit beta-4 [Rattus norvegicus]"]
[null,295027,5162,158.893318445383,505.300738221139,-1.66908382785546,"DOWN",0.000157056818287999,"Pcdh18","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0005509//calcium ion binding","GO:0016337//single organismal cell-cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007417//central nervous system development;GO:0007420//brain development","K16499//protocadherin delta 2","gi|201025402|ref|NP_001093994.1|//protocadherin-18 precursor [Rattus norvegicus];gi|564336371|ref|XP_006232384.1|//PREDICTED: protocadherin-18 isoform X1 [Rattus norvegicus]"]
[null,295228,2256,136.59209023145,65.6819352530604,1.0563054020953,"UP",0.00682681955393746,"Gpatch4","NA","GO:0044822//poly(A) RNA binding","GO:0002244//hematopoietic progenitor cell differentiation","K11135//Pin2-interacting protein X1","gi|68163385|ref|NP_001020150.1|//G patch domain-containing protein 4 [Rattus norvegicus]"]
[null,295279,1258,117.031498407467,242.855750056313,-1.05320276942829,"DOWN",0.000113881142782818,"Fcgr1a","GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0019763//immunoglobulin receptor activity;GO:0019770//IgG receptor activity;GO:0019864//IgG binding;GO:0031774//leukotriene receptor binding","GO:0060100//positive regulation of phagocytosis, engulfment;GO:0006910//phagocytosis, recognition;GO:0042742//defense response to bacterium;GO:0045807//positive regulation of endocytosis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0038094//Fc-gamma receptor signaling pathway;GO:0001794//type IIa hypersensitivity;GO:0032355//response to estradiol;GO:0051707//response to other organism;GO:0045087//innate immune response;GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0001788//antibody-dependent cellular cytotoxicity;GO:0001805//positive regulation of type III hypersensitivity;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0002682//regulation of immune system process;GO:0001798//positive regulation of type IIa hypersensitivity;GO:0006898//receptor-mediated endocytosis;GO:0071871//response to epinephrine;GO:0001802//type III hypersensitivity","K06498//high affinity immunoglobulin gamma Fc receptor I","gi|158631264|ref|NP_001094306.1|//high affinity immunoglobulin gamma Fc receptor I precursor [Rattus norvegicus]"]
[null,295325,6569,5.61221435958181,14.429088276425,-1.36233812472898,"DOWN",0.044460502164837,"Igsf3","NA","NA","NA","K06522//immunoglobulin superfamily, member 2/3","gi|158631164|ref|NP_001099925.1|//immunoglobulin superfamily member 3 precursor [Rattus norvegicus] "]
[null,295620,2429,433.659357361523,1080.19360923401,-1.31665577299687,"DOWN",0.0147275996350078,"Upp2","GO:0005882//intermediate filament;GO:0044444//cytoplasmic part","GO:0016763//transferase activity, transferring pentosyl groups","GO:0009112//nucleobase metabolic process;GO:0008655//pyrimidine-containing compound salvage;GO:0046131//pyrimidine ribonucleoside metabolic process;GO:0009117//nucleotide metabolic process","K00757//uridine phosphorylase [EC:2.4.2.3]","gi|157816987|ref|NP_001099951.1|//uridine phosphorylase 2 [Rattus norvegicus] ;gi|944215419|gb|KQK81700.1|//uridine phosphorylase 2 [Amazona aestiva];gi|795421273|ref|XP_011759027.1|//PREDICTED: uridine phosphorylase 2 isoform X1 [Macaca nemestrina]"]
[null,295629,1234,2906.60889297838,5996.42377109076,-1.04476538446541,"DOWN",0.00400139375387194,"Cd302","GO:0031224//intrinsic component of membrane","GO:0030246//carbohydrate binding","NA","K06722//CD302 antigen;K06559//lymphocyte antigen 75","gi|62078563|ref|NP_001013938.1|//CD302 antigen precursor [Rattus norvegicus]"]
[null,296102,1660,25.0082032524867,9.75336701891571,1.35842915744886,"UP",0.0220406473705244,"Ell3","GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex","NA","GO:0006354//DNA-templated transcription, elongation","K15183//RNA polymerase II elongation factor ELL","gi|58865484|ref|NP_001011957.1|//RNA polymerase II elongation factor ELL3 [Rattus norvegicus]"]
[null,296119,1630,82.7684922033421,39.4388874575761,1.06946282111464,"UP",0.0170295092917369,"Dtwd1","NA","NA","NA","NA","gi|564342737|ref|XP_006234972.1|//PREDICTED: DTW domain-containing protein 1 isoform X1 [Rattus norvegicus]"]
[null,296271,2878,938.744090952408,400.526624723288,1.22883377347147,"UP",0.0106739861175295,"Srxn1","GO:0044444//cytoplasmic part","GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0032559//adenyl ribonucleotide binding;GO:0003676//nucleic acid binding","GO:0008152//metabolic process;GO:0006950//response to stress","K12260//sulfiredoxin [EC:1.8.98.2]","gi|402747055|ref|NP_001041323.3|//sulfiredoxin-1 [Rattus norvegicus]"]
[null,296371,2025,765.131871893,1757.77914630464,-1.19997349096665,"DOWN",0.0009351157743732,"Pltp","NA","GO:0005488//binding","GO:0010876//lipid localization;GO:0048870//cell motility;GO:0042360//vitamin E metabolic process;GO:0006629//lipid metabolic process;GO:0051234//establishment of localization","K08761//phospholipid transfer protein","gi|672048013|ref|XP_008760698.1|//PREDICTED: phospholipid transfer protein isoform X2 [Rattus norvegicus]"]
[null,296500,2757,4.2690765029756,14.0554388352809,-1.71913257646832,"DOWN",0.0143985865372187,"Dlx1","GO:0043231//intracellular membrane-bounded organelle","GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0021543//pallium development;GO:0003002//regionalization;GO:0043066//negative regulation of apoptotic process;GO:0021892//cerebral cortex GABAergic interneuron differentiation;GO:0045686//negative regulation of glial cell differentiation;GO:0021872//forebrain generation of neurons;GO:0001501//skeletal system development;GO:0042476//odontogenesis","K09314//homeobox protein DLX1/4/6","gi|831244539|ref|XP_012667533.1|//PREDICTED: homeobox protein DLX-1 [Otolemur garnettii]"]
[null,296654,2519,147.374587422096,411.851571999224,-1.4826367210045,"DOWN",0.00234223214784981,"Gsn","GO:0031252//cell leading edge;GO:0032991//macromolecular complex;GO:0005856//cytoskeleton;GO:0044421//extracellular region part;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0044444//cytoplasmic part","GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding;GO:0005509//calcium ion binding","GO:0048017//inositol lipid-mediated signaling;GO:0009611//response to wounding;GO:0006810//transport;GO:0001101//response to acid chemical;GO:0009888//tissue development;GO:0051016//barbed-end actin filament capping;GO:0030835//negative regulation of actin filament depolymerization;GO:0045010//actin nucleation;GO:0021782//glial cell development;GO:0046686//response to cadmium ion;GO:0048858//cell projection morphogenesis;GO:0060271//cilium assembly;GO:0007155//cell adhesion;GO:0010033//response to organic substance;GO:0012501//programmed cell death;GO:0051014//actin filament severing","K05768//gelsolin","gi|51854227|ref|NP_001004080.1|//gelsolin precursor [Rattus norvegicus];gi|961762795|ref|XP_014940272.1|//PREDICTED: gelsolin isoform X1 [Acinonyx jubatus];gi|947236949|ref|XP_014444097.1|//PREDICTED: gelsolin [Tupaia chinensis]"]
[null,296655,1792,109.21095236515,268.451572307104,-1.29754430861613,"DOWN",0.00116485359734255,"Stom","GO:0043232//intracellular non-membrane-bounded organelle;GO:0016021//integral component of membrane","NA","GO:0051259//protein oligomerization","K17286//erythrocyte band 7 integral membrane protein","gi|58865500|ref|NP_001011965.1|//erythrocyte band 7 integral membrane protein [Rattus norvegicus]"]
[null,296953,2935,73.5261959502695,160.155205362243,-1.12314043856181,"DOWN",0.000469524142009447,"Irf5","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000975//regulatory region DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding","GO:0032494//response to peptidoglycan;GO:0043065//positive regulation of apoptotic process;GO:0032495//response to muramyl dipeptide;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0019221//cytokine-mediated signaling pathway","K09446//interferon regulatory factor 5","gi|564346042|ref|XP_006236242.1|//PREDICTED: interferon regulatory factor 5 isoform X1 [Rattus norvegicus]"]
[null,297076,1327,11.7114133483259,35.8085137718803,-1.61238744838792,"DOWN",0.00749398481383083,"Gimap6","NA","GO:0032561//guanyl ribonucleotide binding","NA","NA","gi|58865510|ref|NP_001011968.1|//GTPase IMAP family member 6 [Rattus norvegicus]"]
[null,297436,1078,175.513054386626,86.3764215537839,1.0228688857291,"UP",0.0431162317858042,"Chchd6","NA","NA","NA","K17564//coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial","gi|157819769|ref|NP_001100078.1|//MICOS complex subunit Mic25 [Rattus norvegicus]"]
[null,298006,860,59.9501412155116,176.399237735094,-1.55700926957002,"DOWN",0.00247314914469597,"Ccl21","GO:0009986//cell surface","NA","GO:0048534//hematopoietic or lymphoid organ development","K16062//C-C motif chemokine 21","gi|56606078|ref|NP_001008513.1|//C-C motif chemokine 21 precursor [Rattus norvegicus]"]
[null,298069,5193,5.11803223911426,16.3871045177749,-1.67889982299884,"DOWN",0.017383639515893,"Col15a1","GO:0005578//proteinaceous extracellular matrix","NA","NA","K08135//collagen, type XV, alpha","gi|407228400|ref|NP_001094005.1|//collagen alpha-1(XV) chain precursor [Rattus norvegicus]"]
[null,298079,2221,26.1538959194533,70.0667250847633,-1.42170359804251,"DOWN",0.0334048429759732,"Aldh1b1","GO:0031981//nuclear lumen;GO:0044429//mitochondrial part","GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity","GO:0008152//metabolic process","K00128//aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","gi|58865518|ref|NP_001011975.1|//aldehyde dehydrogenase X, mitochondrial precursor [Rattus norvegicus]"]
[null,298296,3350,952.703495159856,391.270737008306,1.28386006603674,"UP",0.0321641891286936,"Pcsk9","GO:0005768//endosome;GO:0044421//extracellular region part;GO:0005783//endoplasmic reticulum;GO:0000323//lytic vacuole","GO:0004175//endopeptidase activity;GO:0070325//lipoprotein particle receptor binding","GO:0007399//nervous system development;GO:0001881//receptor recycling;GO:0010985//negative regulation of lipoprotein particle clearance;GO:0031329//regulation of cellular catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0016485//protein processing;GO:0016125//sterol metabolic process;GO:0031669//cellular response to nutrient levels;GO:0012502//induction of programmed cell death;GO:0048513//animal organ development;GO:0030154//cell differentiation;GO:0032868//response to insulin;GO:0007034//vacuolar transport;GO:0006639//acylglycerol metabolic process;GO:0055092//sterol homeostasis;GO:0019637//organophosphate metabolic process;GO:0006508//proteolysis;GO:0044092//negative regulation of molecular function;GO:0009966//regulation of signal transduction;GO:0002090//regulation of receptor internalization;GO:0032799//low-density lipoprotein receptor particle metabolic process","K13050//proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]","gi|77020250|ref|NP_954862.2|//proprotein convertase subtilisin/kexin type 9 precursor [Rattus norvegicus]"]
[null,298322,2711,36.2526268315901,17.7007217494945,1.03427734764762,"UP",0.0467946579748203,"Lonrf3","NA","GO:0046914//transition metal ion binding","GO:0019538//protein metabolic process;GO:0009207//purine ribonucleoside triphosphate catabolic process","K09553//stress-induced-phosphoprotein 1","gi|300797540|ref|NP_001178514.1|//LON peptidase N-terminal domain and RING finger protein 3 [Rattus norvegicus]"]
[null,298559,1240,316.656872813538,124.415816442896,1.34775049173412,"UP",0.000153736934196108,"Tcea3","GO:0043231//intracellular membrane-bounded organelle","GO:0008135//translation factor activity, RNA binding;GO:0046914//transition metal ion binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006412//translation;GO:0006354//DNA-templated transcription, elongation","K03145//transcription elongation factor S-II","gi|62543505|ref|NP_001015008.1|//transcription elongation factor A protein 3 [Rattus norvegicus]"]
[null,298566,1025,1848.30622474597,3794.45924545989,-1.03769049926112,"DOWN",0.000245285398458858,"C1qa","GO:0043231//intracellular membrane-bounded organelle","NA","GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin","K03986//complement C1q subcomponent subunit A","gi|56606082|ref|NP_001008515.1|//complement C1q subcomponent subunit A precursor [Rattus norvegicus]"]
[null,298606,2253,127.587229234219,57.9461350093296,1.13869958844462,"UP",0.0264429996824353,"Slc25a34","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane","NA","GO:0051234//establishment of localization","K15117//solute carrier family 25, member 34/35","gi|845633169|ref|NP_001013958.2|//solute carrier family 25 member 34 [Rattus norvegicus]"]
[null,298657,1289,37.5311954866899,16.8517531957615,1.15519155331837,"UP",0.0278070520243484,"Car6","NA","GO:0016829//lyase activity;GO:0046872//metal ion binding","NA","K01672//carbonic anhydrase [EC:4.2.1.1]","gi|672054454|ref|XP_008762461.1|//PREDICTED: carbonic anhydrase 6 isoform X1 [Rattus norvegicus];gi|149024685|gb|EDL81182.1|//carbonic anhydrase 6, isoform CRA_a [Rattus norvegicus]"]
[null,298683,2357,37.709811224051,148.002483297551,-1.97260954923068,"DOWN",{"v":1.13888724271976e-08,"d":"1.14E-08"},"Vwa1","GO:0005578//proteinaceous extracellular matrix","NA","GO:0043062//extracellular structure organization","K08132//collagen, type XII, alpha","gi|62078605|ref|NP_001013960.1|//von Willebrand factor A domain-containing protein 1 precursor [Rattus norvegicus]"]
[null,298699,1659,735.181787871427,351.169905642759,1.06593181330704,"UP",0.00479465726898898,"Ppan","GO:0043231//intracellular membrane-bounded organelle","GO:0032559//adenyl ribonucleotide binding","GO:0001558//regulation of cell growth;GO:0010467//gene expression","K14859//ribosome biogenesis protein SSF1/2","gi|58865536|ref|NP_001011980.1|//suppressor of SWI4 1 homolog [Rattus norvegicus]"]
[null,298744,4076,137.119950553032,292.999169890588,-1.09545808297631,"DOWN",0.0204251608888247,"Crim1","GO:0044464//cell part","GO:0019838//growth factor binding;GO:0004866//endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0016049//cell growth","K19721//collagen, type V/XI/XXIV/XXVII, alpha","gi|281182663|ref|NP_001162574.1|//cysteine-rich motor neuron 1 protein precursor [Rattus norvegicus]"]
[null,298857,3925,62.2171580481265,140.192662747017,-1.17202644295471,"DOWN",0.0494841547744081,"Adgrf3","GO:0031224//intrinsic component of membrane","GO:0004888//transmembrane signaling receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08456//G protein-coupled receptor 113","gi|564355128|ref|XP_006239863.1|//PREDICTED: probable G-protein coupled receptor 113 isoform X2 [Rattus norvegicus];gi|564355126|ref|XP_006239862.1|//PREDICTED: probable G-protein coupled receptor 113 isoform X1 [Rattus norvegicus]"]
[null,298906,1929,10.3440678723503,23.9383804280871,-1.21052190229709,"DOWN",0.0407190829866631,"Pqlc3","GO:0044464//cell part","NA","NA","K09660//mannose-P-dolichol utilization defect 1","gi|77993372|ref|NP_001030124.1|//PQ-loop repeat-containing protein 3 precursor [Rattus norvegicus]"]
[null,299145,1981,34.1208210640545,76.2229749200141,-1.15957355318189,"DOWN",0.0359481900039028,"Rhoj","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0044444//cytoplasmic part","GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005525//GTP binding","GO:0065008//regulation of biological quality;GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0007266//Rho protein signal transduction;GO:0007010//cytoskeleton organization;GO:0009966//regulation of signal transduction;GO:0007265//Ras protein signal transduction;GO:0009207//purine ribonucleoside triphosphate catabolic process","K07864//Ras homolog gene family, member J","gi|148704543|gb|EDL36490.1|//ras homolog gene family, member J, isoform CRA_b, partial [Mus musculus];gi|56605718|ref|NP_001008321.1|//rho-related GTP-binding protein RhoJ [Rattus norvegicus]"]
[null,299203,624,93.8731215078746,41.08677141006,1.19203816490634,"UP",0.0116086046634508,"Acyp1","GO:0070062//extracellular exosome","GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0003998//acylphosphatase activity","NA","K01512//acylphosphatase [EC:3.6.1.7]","gi|157822589|ref|NP_001100216.1|//acylphosphatase-1 [Rattus norvegicus];gi|148670916|gb|EDL02863.1|//acylphosphatase 1, erythrocyte (common) type, isoform CRA_c, partial [Mus musculus]"]
[null,299282,1824,29980.5523445739,11132.3447672593,1.42926946836961,"UP",0.00599485503249703,"LOC299282","GO:0005615//extracellular space","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004857//enzyme inhibitor activity","GO:0001937//negative regulation of endothelial cell proliferation;GO:0010951//negative regulation of endopeptidase activity;GO:0016525//negative regulation of angiogenesis;GO:0071385//cellular response to glucocorticoid stimulus;GO:0043434//response to peptide hormone;GO:0032496//response to lipopolysaccharide;GO:0071320//cellular response to cAMP;GO:0006954//inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0043065//positive regulation of apoptotic process;GO:0071354//cellular response to interleukin-6;GO:0071347//cellular response to interleukin-1;GO:0010033//response to organic substance;GO:0034516//response to vitamin B6","K04525//serpin peptidase inhibitor, clade A","gi|13928716|ref|NP_113719.1|//serine protease inhibitor A3N [Rattus norvegicus];gi|57231|emb|CAA34406.1|//unnamed protein product [Rattus norvegicus];gi|32563565|ref|NP_872280.1|//Serine protease inhibitor [Rattus norvegicus];gi|2507387|sp|P05544.3|SPA3L_RAT//RecName: Full=Serine protease inhibitor A3L; Short=Serpin A3L; AltName: Full=CPI-23; AltName: Full=Contrapsin-like protease inhibitor 3; AltName: Full=Serine protease inhibitor 1; Short=SPI-1; Flags: Precursor"]
[null,299691,3083,164.568392723835,81.8079392938952,1.00837451029323,"UP",0.00956655380597546,"Cry1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005739//mitochondrion","GO:0003904//deoxyribodipyrimidine photo-lyase activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0004872//receptor activity;GO:0042826//histone deacetylase binding;GO:0016830//carbon-carbon lyase activity;GO:0005488//binding;GO:0019901//protein kinase binding;GO:0035257//nuclear hormone receptor binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043130//ubiquitin binding;GO:0003914//DNA (6-4) photolyase activity;GO:0000166//nucleotide binding;GO:0019902//phosphatase binding;GO:0008134//transcription factor binding;GO:0009881//photoreceptor activity","GO:0031397//negative regulation of protein ubiquitination;GO:0042754//negative regulation of circadian rhythm;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0006259//DNA metabolic process;GO:0042593//glucose homeostasis;GO:2000850//negative regulation of glucocorticoid secretion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023052//signaling;GO:0032922//circadian regulation of gene expression;GO:0043153//entrainment of circadian clock by photoperiod;GO:0006975//DNA damage induced protein phosphorylation;GO:0032868//response to insulin;GO:0006094//gluconeogenesis;GO:2000001//regulation of DNA damage checkpoint;GO:0006351//transcription, DNA-templated;GO:0048511//rhythmic process;GO:0018298//protein-chromophore linkage;GO:0019915//lipid storage;GO:0006464//cellular protein modification process;GO:0033762//response to glucagon;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway","K02295//cryptochrome","gi|80861398|ref|NP_942045.2|//cryptochrome-1 [Rattus norvegicus]"]
[null,299735,1290,476.706318826724,192.806424850942,1.305947621698,"UP",0.0139598620971863,"Amdhd1","GO:0044444//cytoplasmic part","GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0043169//cation binding","GO:0006536//glutamate metabolic process","K01468//imidazolonepropionase [EC:3.5.2.7]","gi|300796311|ref|NP_001178710.1|//probable imidazolonepropionase [Rattus norvegicus]"]
[null,300242,1696,4.64568537865895,16.5126853369911,-1.82961139581318,"DOWN",0.00866212740632956,"Krt7","GO:0031981//nuclear lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0005737//cytoplasm","GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005488//binding","GO:0022403//cell cycle phase;GO:0006412//translation;GO:0006259//DNA metabolic process","K07605//type II keratin, basic","gi|149031983|gb|EDL86895.1|//keratin complex 2, basic, gene 7, isoform CRA_a [Rattus norvegicus];gi|148672099|gb|EDL04046.1|//keratin 7, isoform CRA_a, partial [Mus musculus]"]
[null,300455,3785,8.72444635609235,22.3017058105134,-1.35401857559513,"DOWN",0.0400935148975666,"Bmper","GO:0044421//extracellular region part","GO:0005488//binding","GO:0001932//regulation of protein phosphorylation;GO:0001775//cell activation;GO:0030334//regulation of cell migration;GO:0043410//positive regulation of MAPK cascade;GO:0030509//BMP signaling pathway","K18273//alpha-tectorin;K03900//von Willebrand factor","gi|209447103|ref|NP_001129271.1|//BMP-binding endothelial regulator protein precursor [Rattus norvegicus] "]
[null,300644,2831,15.9356285741935,35.2485265521713,-1.14530702494754,"DOWN",0.0378455746648412,"Gramd1b","NA","NA","NA","K19951//TBC1 domain family member 8/9","gi|300798184|ref|NP_001178545.1|//GRAM domain-containing protein 1B [Rattus norvegicus]"]
[null,301056,3959,203.348504570334,475.076404471936,-1.22420517324611,"DOWN",0.0003380664069145,"Ctdspl","GO:0043231//intracellular membrane-bounded organelle;GO:0034679//integrin alpha9-beta1 complex;GO:0009925//basal plasma membrane","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0016791//phosphatase activity","GO:0007155//cell adhesion;GO:0030593//neutrophil chemotaxis;GO:0007229//integrin-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process","K15731//carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16];K06585//integrin alpha 9","gi|148677300|gb|EDL09247.1|//CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, partial [Mus musculus];gi|165377045|ref|NP_598482.2|//integrin alpha-9 isoform a precursor [Mus musculus]"]
[null,301265,1797,36.2291870096131,89.9267738433833,-1.31159828062511,"DOWN",0.0394721148061027,"Pla2g7","GO:0044421//extracellular region part","GO:0008289//lipid binding","GO:0006952//defense response;GO:0006629//lipid metabolic process","K01062//platelet-activating factor acetylhydrolase [EC:3.1.1.47]","gi|564367541|ref|XP_006244668.1|//PREDICTED: platelet-activating factor acetylhydrolase isoform X1 [Rattus norvegicus]"]
[null,301460,4550,289.288029113544,652.129585398558,-1.17265204744213,"DOWN",0.0043030503156867,"Adam23","GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0004222//metalloendopeptidase activity;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding;GO:0005102//receptor binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0006508//proteolysis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway","K06837//disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-]","gi|672065125|ref|XP_008765312.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 23 isoform X2 [Rattus norvegicus];gi|672065123|ref|XP_008765311.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 23 isoform X1 [Rattus norvegicus];gi|585172120|ref|XP_006738017.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 23 [Leptonychotes weddellii];gi|71361651|ref|NP_001025070.1|//disintegrin and metalloproteinase domain-containing protein 23 [Rattus norvegicus]"]
[null,301575,1984,515.132390643186,1037.38373212497,-1.00993448895032,"DOWN",0.00745826919765984,"Itm2c","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0001540//beta-amyloid binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0032559//adenyl ribonucleotide binding","GO:0010977//negative regulation of neuron projection development;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0010975//regulation of neuron projection development;GO:0043068//positive regulation of programmed cell death","K18265//integral membrane protein 2C","gi|297265084|ref|XP_001112946.2|//PREDICTED: integral membrane protein 2C [Macaca mulatta];gi|57527254|ref|NP_001009674.1|//integral membrane protein 2C [Rattus norvegicus]"]
[null,303068,6286,50.5800461025923,123.597224641635,-1.28900609099198,"DOWN",0.00297515904792428,"Adam19","GO:0031224//intrinsic component of membrane","GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding","GO:0048513//animal organ development;GO:0033619//membrane protein proteolysis;GO:0007166//cell surface receptor signaling pathway","K08608//disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-]","gi|237681071|ref|NP_001153700.1|//disintegrin and metalloproteinase domain-containing protein 19 precursor [Rattus norvegicus]"]
[null,303135,4008,37.9172806214732,78.158614642263,-1.04354939611553,"DOWN",0.0181149808556463,"Sept8","GO:0032156//septin cytoskeleton","GO:0032561//guanyl ribonucleotide binding","GO:0009987//cellular process","K16939//septin 6/8/11","gi|148701638|gb|EDL33585.1|//septin 8, isoform CRA_c, partial [Mus musculus]"]
[null,303439,2671,11.0842423708865,36.2636848794875,-1.71001536718845,"DOWN",0.0101391458432085,"Mmd","GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0004871//signal transducer activity","GO:0023052//signaling;GO:0008219//cell death","K11064//monocyte to macrophage differentiation protein","gi|444720844|gb|ELW61613.1|//Monocyte to macrophage differentiation protein [Tupaia chinensis]"]
[null,303517,4901,25.7273875440865,198.570336207358,-2.94827324639788,"DOWN",{"v":2.63337936676084e-07,"d":"2.63E-07"},"Tns4","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0043232//intracellular non-membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0005737//cytoplasm","GO:0003779//actin binding","GO:0012501//programmed cell death;GO:0033036//macromolecule localization;GO:0008104//protein localization;GO:0006915//apoptotic process","K04608//metabotropic glutamate receptor 6/7/8;K18080//tensin;K09383//paired box protein 5","gi|67846032|ref|NP_001020052.1|//tensin-4 precursor [Rattus norvegicus];gi|524952046|ref|XP_005076024.1|//PREDICTED: tensin-4 [Mesocricetus auratus];gi|795356143|ref|XP_011785224.1|//PREDICTED: tensin-4 [Colobus angolensis palliatus]"]
[null,303539,3123,586.446270862649,258.426202071607,1.18224658358871,"UP",0.000474336724504271,"Kat2a","NA","NA","NA","K06062//histone acetyltransferase [EC:2.3.1.48]","gi|157817171|ref|NP_001100520.1|//histone acetyltransferase KAT2A [Rattus norvegicus] ;gi|564374228|ref|XP_006247379.1|//PREDICTED: histone acetyltransferase KAT2A isoform X1 [Rattus norvegicus]"]
[null,303666,777,43.8190228730241,136.591440103568,-1.64023785689036,"DOWN",0.00014040172898071,"RGD1561778","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004871//signal transducer activity;GO:0005488//binding","GO:0050715//positive regulation of cytokine secretion","K06719//CD300 antigen","gi|269973887|ref|NP_001161756.1|//immune activating receptor CD300d2 precursor [Rattus norvegicus];gi|269973889|ref|NP_001161757.1|//immune activating receptor CD300d1 precursor [Rattus norvegicus]"]
[null,303701,1561,83.3063156558651,190.832253677837,-1.19580725120299,"DOWN",0.00123405051591569,"C1qtnf1","GO:0044421//extracellular region part","NA","GO:0051259//protein oligomerization","K19470//complement C1q tumor necrosis factor-related protein 6","gi|672069802|ref|XP_008766596.1|//PREDICTED: complement C1q tumor necrosis factor-related protein 1 isoform X3 [Rattus norvegicus]"]
[null,303772,4338,298.944416437753,98.1770873229908,1.60641899390363,"UP",0.00304927505101791,"Slc16a6","GO:0005887//integral component of plasma membrane","GO:0015129//lactate transmembrane transporter activity","GO:0006810//transport;GO:0035879//plasma membrane lactate transport","K08183//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 6","gi|149054651|gb|EDM06468.1|//rCG32742, isoform CRA_c [Rattus norvegicus];gi|672069808|ref|XP_008766597.1|//PREDICTED: monocarboxylate transporter 7 isoform X2 [Rattus norvegicus]"]
[null,303828,3897,47.1159229752782,100.855862199785,-1.09800833165117,"DOWN",0.00544429122237298,"Etv5","GO:0043231//intracellular membrane-bounded organelle","GO:0043565//sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0006979//response to oxidative stress;GO:0006355//regulation of transcription, DNA-templated;GO:0042078//germ-line stem cell division;GO:0045597//positive regulation of cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060688//regulation of morphogenesis of a branching structure","K15593//ets translocation variant 5","gi|148665211|gb|EDK97627.1|//mCG127346, isoform CRA_b, partial [Mus musculus]"]
[null,304050,748,1.68744090318535,4.46886442706849,-1.40507130042159,"DOWN",0.0363100164159758,"Fam3b","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0005641//nuclear envelope lumen","GO:0005125//cytokine activity;GO:0005102//receptor binding","GO:0030072//peptide hormone secretion;GO:0030073//insulin secretion;GO:0006915//apoptotic process","K07747//beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45];K09666//beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]","gi|157820883|ref|NP_001100572.1|//protein FAM3B [Rattus norvegicus];gi|564376354|ref|XP_006248219.1|//PREDICTED: protein FAM3B isoform X1 [Rattus norvegicus]"]
[null,304135,2787,4.46161098774533,16.6013435264199,-1.89566336766418,"DOWN",0.0061256762816928,"Adamts5","GO:0031012//extracellular matrix","GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding","GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway","K08620//a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-]","gi|38454260|ref|NP_942056.1|//A disintegrin and metalloproteinase with thrombospondin motifs 5 precursor [Rattus norvegicus]"]
[null,304244,10792,25.0480131618606,60.7408616768698,-1.27797120321326,"DOWN",0.0115329383616742,"Fry","NA","NA","NA","NA","gi|281371436|ref|NP_001163869.1|//protein furry homolog [Rattus norvegicus]"]
[null,304816,3937,6.89256748446085,28.3892131752128,-2.04222947171691,"DOWN",0.00188743951693696,"Lmod1","NA","NA","NA","K10370//tropomodulin","gi|157821571|ref|NP_001100649.1|//leiomodin-1 [Rattus norvegicus] "]
[null,304860,2498,27.7621007136175,77.9090836417221,-1.48867480754749,"DOWN",0.000612175328143165,"Npl","GO:0044424//intracellular part","GO:0016833//oxo-acid-lyase activity","GO:0044238//primary metabolic process","K01639//N-acetylneuraminate lyase [EC:4.1.3.3]","gi|62078697|ref|NP_001014006.1|//N-acetylneuraminate lyase [Rattus norvegicus]"]
[null,304884,5341,1195.87927488075,384.213644086693,1.638091097882,"UP",0.000992802363665696,"Tor3a","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen","GO:0003855//3-dehydroquinate dehydratase activity;GO:0016836//hydro-lyase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding;GO:0016887//ATPase activity","GO:0051084//'de novo' posttranslational protein folding","K01056//peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]","gi|57527353|ref|NP_001009683.1|//torsin-3A precursor [Rattus norvegicus]"]
[null,304960,3122,20.096493302506,57.9357884086322,-1.52751102979532,"DOWN",0.00295698138422517,"Olfml2b","NA","NA","NA","K04592//latrophilin 1","gi|157821323|ref|NP_001100665.1|//olfactomedin-like protein 2B precursor [Rattus norvegicus] "]
[null,304966,1178,65.9548219374465,163.231215517916,-1.30736693399621,"DOWN",0.00197000777260545,"Fcgr3a","GO:0031224//intrinsic component of membrane","GO:0019865//immunoglobulin binding;GO:0004871//signal transducer activity","GO:0009611//response to wounding;GO:0002376//immune system process;GO:0023052//signaling","K06463//low affinity immunoglobulin gamma Fc receptor III","gi|46485398|ref|NP_997486.1|//Fc fragment of IgG, low affinity IIIa, receptor precursor [Rattus norvegicus]"]
[null,304988,1946,56.5821533747223,124.517326369796,-1.13792751652856,"DOWN",0.0474235955257034,"Mnda","GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0044822//poly(A) RNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0001047//core promoter binding","GO:0035456//response to interferon-beta;GO:0050853//B cell receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045669//positive regulation of osteoblast differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0035458//cellular response to interferon-beta;GO:0048839//inner ear development;GO:0030889//negative regulation of B cell proliferation;GO:0045597//positive regulation of cell differentiation","K12966//absent in melanoma 2;K12971//interferon-activable protein 202;K20914//gamma-interferon-inducible protein 16","gi|58865634|ref|NP_001012029.1|//myeloid cell nuclear differentiation antigen [Rattus norvegicus]"]
[null,305081,2152,9.09540684414733,25.3565198474553,-1.479146673637,"DOWN",0.012515372713306,"Cd34","GO:0016020//membrane;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0009925//basal plasma membrane;GO:0045171//intercellular bridge;GO:0044424//intracellular part;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0036053//glomerular endothelium fenestra","GO:0030246//carbohydrate binding;GO:0043168//anion binding;GO:0043199//sulfate binding;GO:0008134//transcription factor binding","GO:1901215//negative regulation of neuron death;GO:0008217//regulation of blood pressure;GO:0032733//positive regulation of interleukin-10 production;GO:0061042//vascular wound healing;GO:0003094//glomerular filtration;GO:0071971//extracellular exosome assembly;GO:1900041//negative regulation of interleukin-2 secretion;GO:0010629//negative regulation of gene expression;GO:0032720//negative regulation of tumor necrosis factor production;GO:1900168//positive regulation of glial cell-derived neurotrophic factor secretion;GO:0071425//hematopoietic stem cell proliferation;GO:0002376//immune system process;GO:0038001//paracrine signaling;GO:0072011//glomerular endothelium development;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0045766//positive regulation of angiogenesis;GO:0035759//mesangial cell-matrix adhesion;GO:1900038//negative regulation of cellular response to hypoxia;GO:0001935//endothelial cell proliferation;GO:1900035//negative regulation of cellular response to heat;GO:0030195//negative regulation of blood coagulation;GO:0016337//single organismal cell-cell adhesion;GO:0042482//positive regulation of odontogenesis;GO:0007165//signal transduction;GO:2001214//positive regulation of vasculogenesis;GO:0050900//leukocyte migration;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0010628//positive regulation of gene expression;GO:0060290//transdifferentiation;GO:0001894//tissue homeostasis;GO:0007155//cell adhesion;GO:0071636//positive regulation of transforming growth factor beta production;GO:0072254//metanephric glomerular mesangial cell differentiation","K06474//CD34 antigen","gi|168997382|gb|ACA42447.1|//CD34 antigen isoform 2 [Rattus norvegicus];gi|157821377|ref|NP_001100672.1|//hematopoietic progenitor cell antigen CD34 precursor [Rattus norvegicus]"]
[null,305166,2983,1043.24113526682,340.390027974709,1.61581198390512,"UP",0.0011403808956761,"Gpat3","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0008374//O-acyltransferase activity","GO:0032006//regulation of TOR signaling;GO:0006641//triglyceride metabolic process;GO:0006644//phospholipid metabolic process;GO:0009966//regulation of signal transduction;GO:0019432//triglyceride biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process","K13506//glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]","gi|71043846|ref|NP_001020841.1|//glycerol-3-phosphate acyltransferase 3 [Rattus norvegicus]"]
[null,305373,1549,47.2812275303367,11.8967483097295,1.99070019031946,"UP",0.0042026630943744,"Hmgb3","GO:0043231//intracellular membrane-bounded organelle;GO:0043232//intracellular non-membrane-bounded organelle","GO:0003677//DNA binding","GO:0045577//regulation of B cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0006259//DNA metabolic process","K11296//high mobility group protein B3","gi|148694630|gb|EDL26577.1|//mCG10155, isoform CRA_d, partial [Mus musculus]"]
[null,305494,3853,95.739675592605,224.534173113311,-1.22974621081081,"DOWN",0.00310225652172051,"Aebp1","GO:0044421//extracellular region part;GO:0044424//intracellular part","GO:0008238//exopeptidase activity;GO:0003712//transcription cofactor activity;GO:0005488//binding","GO:0006351//transcription, DNA-templated","K08639//carboxypeptidase X2","gi|155369293|ref|NP_001094440.1|//adipocyte enhancer-binding protein 1 precursor [Rattus norvegicus];gi|564384496|ref|XP_006251378.1|//PREDICTED: adipocyte enhancer-binding protein 1 isoform X1 [Rattus norvegicus]"]
[null,305501,5072,59.0242615464066,120.388322784935,-1.02831547078844,"DOWN",0.0326291634447125,"Ikzf1","GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000775//chromosome, centromeric region","GO:0043565//sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0001071//nucleic acid binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048537//mucosal-associated lymphoid tissue development;GO:0006325//chromatin organization;GO:0030854//positive regulation of granulocyte differentiation;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0007420//brain development;GO:0035264//multicellular organism growth","K09228//KRAB domain-containing zinc finger protein;K09220//IKAROS family zinc finger protein","gi|752397218|ref|XP_002917670.2|//PREDICTED: DNA-binding protein Ikaros isoform X1 [Ailuropoda melanoleuca];gi|148708694|gb|EDL40641.1|//zinc finger protein, subfamily 1A, 1 (Ikaros), isoform CRA_c [Mus musculus];gi|752397232|ref|XP_011221233.1|//PREDICTED: DNA-binding protein Ikaros isoform X5 [Ailuropoda melanoleuca];gi|667262892|ref|XP_008568105.1|//PREDICTED: DNA-binding protein Ikaros isoform X3 [Galeopterus variegatus]"]
[null,306071,3504,236.496200233469,596.043994969469,-1.3336018181886,"DOWN",0.000610979759494643,"Lcp1","GO:0031252//cell leading edge;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0044459//plasma membrane part;GO:0005925//focal adhesion;GO:0001891//phagocytic cup;GO:0030175//filopodium;GO:0005884//actin filament;GO:0001726//ruffle;GO:0001725//stress fiber;GO:0002102//podosome;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part","GO:0003779//actin binding;GO:0051015//actin filament binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0051020//GTPase binding","GO:0016477//cell migration;GO:0071803//positive regulation of podosome assembly;GO:0010737//protein kinase A signaling;GO:0002285//lymphocyte activation involved in immune response;GO:0006950//response to stress;GO:0006886//intracellular protein transport;GO:0022617//extracellular matrix disassembly;GO:0009887//animal organ morphogenesis;GO:0007015//actin filament organization;GO:0051017//actin filament bundle assembly;GO:0002286//T cell activation involved in immune response;GO:0033157//regulation of intracellular protein transport","K17276//plastin-2","gi|564387027|ref|XP_006252380.1|//PREDICTED: plastin-2 isoform X2 [Rattus norvegicus];gi|847033220|ref|XP_012805945.1|//PREDICTED: plastin-2 isoform X2 [Jaculus jaculus]"]
[null,306285,4070,31.7346037340113,5.28272263056647,2.58670325971643,"UP",0.000139384907175837,"Syt15","GO:0031224//intrinsic component of membrane","NA","NA","K19914//synaptotagmin-15","gi|54607175|ref|NP_853663.2|//synaptotagmin-15 [Rattus norvegicus]"]
[null,306527,1630,96.014385357771,43.3860205530644,1.14602030831376,"UP",0.0434803141383188,"Dusp26","GO:0043231//intracellular membrane-bounded organelle","GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding","GO:0006470//protein dephosphorylation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","gi|640815631|ref|XP_008064591.1|//PREDICTED: dual specificity protein phosphatase 26 [Tarsius syrichta]"]
[null,306636,1158,12.774948615476,31.9603020698696,-1.32296355559101,"DOWN",0.0389473248310199,"Efnb2","GO:0016020//membrane","GO:0005515//protein binding","GO:0001944//vasculature development;GO:0009653//anatomical structure morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0048869//cellular developmental process","K05463//ephrin-B","gi|157822681|ref|NP_001100798.1|//ephrin-B2 [Rattus norvegicus]"]
[null,306825,3069,46.8029854522234,98.6073662507414,-1.07509486518903,"DOWN",0.00610447659816354,"Mylip","GO:0043232//intracellular non-membrane-bounded organelle;GO:0044425//membrane part","GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding","GO:0055092//sterol homeostasis;GO:0031647//regulation of protein stability;GO:0010985//negative regulation of lipoprotein particle clearance;GO:0016567//protein ubiquitination;GO:0031329//regulation of cellular catabolic process;GO:0048731//system development;GO:0009896//positive regulation of catabolic process","K10637//E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]","gi|406362834|ref|NP_001100814.2|//E3 ubiquitin-protein ligase MYLIP [Rattus norvegicus]"]
[null,306860,3837,114.072224795644,233.572455312404,-1.03392259475901,"DOWN",0.00421624955887513,"Gcnt2","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity","GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0051897//positive regulation of protein kinase B signaling;GO:0006486//protein glycosylation;GO:0030335//positive regulation of cell migration;GO:0006023//aminoglycan biosynthetic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010608//posttranscriptional regulation of gene expression;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010812//negative regulation of cell-substrate adhesion;GO:0032501//multicellular organismal process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0036438//maintenance of lens transparency;GO:0008284//positive regulation of cell proliferation","K00742//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.150]","gi|148709011|gb|EDL40957.1|//glucosaminyl (N-acetyl) transferase 2, I-branching enzyme, isoform CRA_a, partial [Mus musculus];gi|40849880|gb|AAR95652.1|//I-branching beta-1,6-acetylglucosaminyltransferase family polypeptide 1 [Rattus norvegicus];gi|48040475|ref|NP_001001511.1|//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase [Rattus norvegicus]"]
[null,306941,2470,21.6034109278968,51.7620860013408,-1.26063664363453,"DOWN",0.0117817159396933,"Lrrc16a","NA","NA","NA","K20493//leucine-rich repeat-containing protein 16","gi|672081783|ref|XP_008769867.1|//PREDICTED: leucine-rich repeat-containing protein 16A isoform X6 [Rattus norvegicus];gi|300794513|ref|NP_001178621.1|//leucine-rich repeat-containing protein 16A [Rattus norvegicus]"]
[null,307171,2488,48.0248246559504,99.4715667248502,-1.05050385349743,"DOWN",0.0171380960630228,"Apbb1ip","GO:0016020//membrane;GO:0044424//intracellular part","NA","NA","K17704//amyloid beta A4 precursor protein-binding family B member 1-interacting protein","gi|281332190|ref|NP_001094047.1|//amyloid beta A4 precursor protein-binding family B member 1-interacting protein [Rattus norvegicus]"]
[null,307212,2922,58.7465579707132,141.352535949303,-1.26672153613294,"DOWN",0.00072007852157134,"Cndp1","GO:0005829//cytosol;GO:0044444//cytoplasmic part","GO:0070573//metallodipeptidase activity;GO:0004180//carboxypeptidase activity;GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0008270//zinc ion binding","GO:0006508//proteolysis;GO:0019538//protein metabolic process;GO:0032268//regulation of cellular protein metabolic process;GO:0043171//peptide catabolic process","K05604//beta-Ala-His dipeptidase [EC:3.4.13.20]","gi|56090459|ref|NP_001007688.1|//beta-Ala-His dipeptidase [Rattus norvegicus];gi|625242672|ref|XP_007612561.1|//PREDICTED: beta-Ala-His dipeptidase isoform X2, partial [Cricetulus griseus]"]
[null,307270,2899,48.6062264175276,124.7898989463,-1.36028812189695,"DOWN",0.00111666389873342,"Me2","GO:0043231//intracellular membrane-bounded organelle","GO:0043169//cation binding;GO:0000166//nucleotide binding;GO:0004470//malic enzyme activity","GO:0043648//dicarboxylic acid metabolic process","K00027//malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]","gi|564393980|ref|XP_006254985.1|//PREDICTED: NAD-dependent malic enzyme, mitochondrial isoform X1 [Rattus norvegicus]"]
[null,307398,5343,114.66626096178,28.5536061948218,2.00569609152002,"UP",{"v":1.49585417489416e-06,"d":"1.50E-06"},"Arhgef37","GO:0005737//cytoplasm","GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0035023//regulation of Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity","K12365//phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein;K20710//Rho guanine nucleotide exchange factor 37","gi|155369301|ref|NP_001094444.1|//rho guanine nucleotide exchange factor 37 [Rattus norvegicus];gi|564393678|ref|XP_006254869.1|//PREDICTED: rho guanine nucleotide exchange factor 37 isoform X1 [Rattus norvegicus]"]
[null,307403,4061,1031.42723690954,2190.88935234916,-1.08687457655716,"DOWN",0.000584712485258919,"Csf1r","GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:1990682//CSF1-CSF1R complex","GO:0019955//cytokine binding;GO:0005524//ATP binding;GO:0005011//macrophage colony-stimulating factor receptor activity;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0032559//adenyl ribonucleotide binding;GO:0004871//signal transducer activity","GO:0014706//striated muscle tissue development;GO:0030335//positive regulation of cell migration;GO:0090197//positive regulation of chemokine secretion;GO:0045217//cell-cell junction maintenance;GO:0045672//positive regulation of osteoclast differentiation;GO:0021772//olfactory bulb development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0045124//regulation of bone resorption;GO:0045087//innate immune response;GO:0007411//axon guidance;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0031529//ruffle organization;GO:0021879//forebrain neuron differentiation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0046777//protein autophosphorylation;GO:0006954//inflammatory response;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006464//cellular protein modification process;GO:0046488//phosphatidylinositol metabolic process;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0008284//positive regulation of cell proliferation","K05090//macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]","gi|71361659|ref|NP_001025072.1|//macrophage colony-stimulating factor 1 receptor precursor [Rattus norvegicus];gi|74212790|dbj|BAE33360.1|//unnamed protein product [Mus musculus]"]
[null,307618,3912,341.097167041984,693.651801960604,-1.02402887033916,"DOWN",0.0025431397172401,"Cdh5","GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex","GO:0046872//metal ion binding;GO:0019902//phosphatase binding","GO:0030010//establishment of cell polarity;GO:0008283//cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0001568//blood vessel development","K06533//cadherin 5, type 2, VE-cadherin","gi|74198375|dbj|BAE39672.1|//unnamed protein product [Mus musculus];gi|157817743|ref|NP_001100877.1|//cadherin-5 [Rattus norvegicus] "]
[null,308099,5193,4.5690035236531,12.9300252961226,-1.50077363734184,"DOWN",0.0334479745833415,"Fndc1","NA","NA","NA","K06766//neogenin","gi|84370262|ref|NP_001033704.1|//fibronectin type III domain-containing protein 1 [Rattus norvegicus]"]
[null,308100,1971,598.560491464409,247.513387710295,1.27399049457211,"UP",0.00805969365664989,"Acat2","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0044444//cytoplasmic part","GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0016453//C-acetyltransferase activity","GO:0001889//liver development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0031670//cellular response to nutrient;GO:0046952//ketone body catabolic process;GO:0071398//cellular response to fatty acid;GO:0044248//cellular catabolic process;GO:0007584//response to nutrient;GO:0045797//positive regulation of intestinal cholesterol absorption;GO:0070542//response to fatty acid","K00626//acetyl-CoA C-acetyltransferase [EC:2.3.1.9]","gi|55741502|ref|NP_001006996.1|//acetyl-CoA acetyltransferase, cytosolic [Rattus norvegicus];gi|148747461|ref|NP_033364.2|//acetyl-CoA acetyltransferase, cytosolic [Mus musculus]"]
[null,308501,3411,341.56442882389,853.298679388208,-1.32089307747674,"DOWN",0.00392969022167227,"Cd22","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0015026//coreceptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway","K06467//CD22 antigen","gi|6048962|gb|AAF02417.1|AF102134_1//B lymphocyte cell adhesion molecule [Mus musculus];gi|157819397|ref|NP_001100973.1|//B-cell receptor CD22 precursor [Rattus norvegicus] ;gi|672035735|ref|XP_008757376.1|//PREDICTED: B-cell receptor CD22 isoform X2 [Rattus norvegicus]"]
[null,308831,8565,3.3708904474246,10.9268849308288,-1.69668052559772,"DOWN",0.015894981252418,"Tenm4","NA","NA","NA","K06252//tenascin","gi|300798434|ref|NP_001178557.1|//teneurin-4 [Rattus norvegicus] "]
[null,308899,6702,216.595429776967,464.921307693271,-1.10198374516513,"DOWN",0.0212125075870271,"Mrvi1","GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum","GO:0005515//protein binding","GO:0019934//cGMP-mediated signaling;GO:0060087//relaxation of vascular smooth muscle","K12337//inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate","gi|157419144|ref|NP_001098681.1|//protein MRVI1 isoform a [Rattus norvegicus] "]
[null,308937,3305,142.8482321626,65.0244230922023,1.1354295826187,"UP",0.0262146966673352,"Wee1","GO:0031981//nuclear lumen","GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0032559//adenyl ribonucleotide binding","GO:0048858//cell projection morphogenesis;GO:0000087//mitotic M phase;GO:0007163//establishment or maintenance of cell polarity;GO:0007010//cytoskeleton organization;GO:0006468//protein phosphorylation","K06632//wee1-like protein kinase [EC:2.7.11.1]","gi|60678262|ref|NP_001012760.1|//wee1-like protein kinase [Rattus norvegicus]"]
[null,308965,1257,8.71267697758235,23.1835996569263,-1.41191662587,"DOWN",0.0254913311508577,"Chp2","GO:0044424//intracellular part;GO:0044459//plasma membrane part","GO:0046872//metal ion binding;GO:0005515//protein binding","GO:0006875//cellular metal ion homeostasis;GO:0006885//regulation of pH;GO:0030001//metal ion transport","K17611//calcineurin B homologous protein 2","gi|672037923|ref|XP_008757967.1|//PREDICTED: calcineurin B homologous protein 2 isoform X2 [Rattus norvegicus]"]
[null,308995,3799,212.759360781134,491.778172740358,-1.20878509564594,"DOWN",0.00944193594755388,"Itgal","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane","GO:0004871//signal transducer activity;GO:0046983//protein dimerization activity","GO:0042098//T cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0002286//T cell activation involved in immune response;GO:0009967//positive regulation of signal transduction;GO:0007166//cell surface receptor signaling pathway","K05718//integrin alpha L","gi|359751455|ref|NP_001240801.1|//integrin alpha-L isoform 1 precursor [Mus musculus] ;gi|77404269|ref|NP_001029170.1|//integrin alpha-L precursor [Rattus norvegicus]"]
[null,309136,2668,302.081018391711,150.478174273455,1.00538128340934,"UP",0.0293691547720362,"Oraov1","GO:0035861//site of double-strand break;GO:0030896//checkpoint clamp complex","NA","GO:0033314//mitotic DNA replication checkpoint;GO:0031573//intra-S DNA damage checkpoint;GO:0000724//double-strand break repair via homologous recombination;GO:0044778//meiotic DNA integrity checkpoint;GO:0006289//nucleotide-excision repair","K10903//HUS1 checkpoint protein","gi|157817260|ref|NP_001101035.1|//oral cancer-overexpressed protein 1 [Rattus norvegicus] ;gi|564332230|ref|XP_006230844.1|//PREDICTED: oral cancer-overexpressed protein 1 isoform X1 [Rattus norvegicus];gi|564332233|ref|XP_006230845.1|//PREDICTED: oral cancer-overexpressed protein 1 isoform X2 [Rattus norvegicus]"]
[null,309147,1913,21.7636469273267,49.7359583760579,-1.19236894780901,"DOWN",0.0426812169680881,"Aldh3b1","NA","GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","GO:0044237//cellular metabolic process","K00129//aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]","gi|672039348|ref|XP_008758354.1|//PREDICTED: aldehyde dehydrogenase family 3 member B1 isoform X2 [Rattus norvegicus];gi|532015848|ref|XP_005351687.1|//PREDICTED: aldehyde dehydrogenase family 3 member B1 isoform X1 [Microtus ochrogaster]"]
[null,309375,2772,207.967117746544,846.949189018124,-2.02591998270587,"DOWN",{"v":2.63418284828848e-06,"d":"2.63E-06"},"Marveld1","NA","NA","NA","NA","gi|157820241|ref|NP_001101060.1|//MARVEL domain-containing protein 1 [Rattus norvegicus]"]
[null,309513,2783,1054.72778514246,414.901708260108,1.3460291992952,"UP",0.0049900002146827,"Ppp1r3c","GO:0044444//cytoplasmic part","GO:0005515//protein binding;GO:0016791//phosphatase activity","GO:0006886//intracellular protein transport;GO:0005978//glycogen biosynthetic process;GO:0005980//glycogen catabolic process","K07189//protein phosphatase 1 regulatory subunit 3A/B/C/D/E","gi|58865716|ref|NP_001012072.1|//protein phosphatase 1 regulatory subunit 3C [Rattus norvegicus]"]
[null,309621,1136,317.295348472844,903.930119165748,-1.51038487379074,"DOWN",0.00101818040934275,"RT1-Ba","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0042611//MHC protein complex;GO:0000323//lytic vacuole","GO:0042605//peptide antigen binding;GO:0046982//protein heterodimerization activity;GO:0003823//antigen binding;GO:0023026//MHC class II protein complex binding","GO:0071385//cellular response to glucocorticoid stimulus;GO:0045580//regulation of T cell differentiation;GO:0002506//polysaccharide assembly with MHC class II protein complex;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0050890//cognition;GO:0042130//negative regulation of T cell proliferation;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0034341//response to interferon-gamma;GO:0045582//positive regulation of T cell differentiation;GO:0002478//antigen processing and presentation of exogenous peptide antigen","K06752//major histocompatibility complex, class II","gi|57012346|ref|NP_001008831.1|//rano class II histocompatibility antigen, B alpha chain precursor [Rattus norvegicus];gi|655348966|gb|AIC84033.1|//MHC class II antigen A alpha isoform-004 [Mus musculus]"]
[null,309622,1542,445.576895039282,1254.76095214805,-1.49366620850985,"DOWN",0.00252306345868255,"RT1-Bb","GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0042613//MHC class II protein complex;GO:0031902//late endosome membrane;GO:0042611//MHC protein complex;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0016021//integral component of membrane;GO:0005769//early endosome","GO:0015643//toxic substance binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0023026//MHC class II protein complex binding;GO:1990405//protein antigen binding;GO:0042605//peptide antigen binding;GO:0003823//antigen binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0071346//cellular response to interferon-gamma;GO:0042130//negative regulation of T cell proliferation;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002579//positive regulation of antigen processing and presentation;GO:0071315//cellular response to morphine;GO:0002506//polysaccharide assembly with MHC class II protein complex;GO:0071549//cellular response to dexamethasone stimulus;GO:0046634//regulation of alpha-beta T cell activation;GO:0050890//cognition;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002344//B cell affinity maturation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0009623//response to parasitic fungus;GO:0002478//antigen processing and presentation of exogenous peptide antigen","K06752//major histocompatibility complex, class II","gi|51854235|ref|NP_001004084.1|//rano class II histocompatibility antigen, B-1 beta chain precursor [Rattus norvegicus]"]
[null,309684,3125,401.984188428952,914.328599895072,-1.18557399178133,"DOWN",0.000254893241213351,"Itgb2","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0034687//integrin alphaL-beta2 complex;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft","GO:0050839//cell adhesion molecule binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0001948//glycoprotein binding;GO:0004871//signal transducer activity;GO:0030369//ICAM-3 receptor activity;GO:0032403//protein complex binding","GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0031623//receptor internalization;GO:0007166//cell surface receptor signaling pathway;GO:0035987//endodermal cell differentiation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0001932//regulation of protein phosphorylation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0034113//heterotypic cell-cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0006909//phagocytosis;GO:0043113//receptor clustering;GO:0050798//activated T cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0043542//endothelial cell migration;GO:0030593//neutrophil chemotaxis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030595//leukocyte chemotaxis;GO:0031589//cell-substrate adhesion;GO:0006954//inflammatory response;GO:0007568//aging;GO:0045123//cellular extravasation;GO:0007160//cell-matrix adhesion;GO:0030101//natural killer cell activation;GO:0042098//T cell proliferation;GO:0045765//regulation of angiogenesis;GO:0031328//positive regulation of cellular biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process","K06464//integrin beta 2","gi|149043651|gb|EDL97102.1|//rCG60535, isoform CRA_b [Rattus norvegicus];gi|163937849|ref|NP_001032869.2|//integrin beta-2 precursor [Rattus norvegicus]"]
[null,309816,6051,54.8925442511289,120.752075661776,-1.13736587399949,"DOWN",0.0137949024292468,"Lama4","GO:0043256//laminin complex","GO:0005515//protein binding;GO:0005198//structural molecule activity","GO:0001944//vasculature development;GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0045444//fat cell differentiation;GO:2000026//regulation of multicellular organismal development","K06241//laminin, alpha 4","gi|827342570|ref|NP_001296376.1|//laminin subunit alpha-4 precursor [Rattus norvegicus] "]
[null,310132,4653,204.788562816595,821.649001087257,-2.00438707805233,"DOWN",0.000127722140763984,"Osmr","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0005900//oncostatin-M receptor complex","GO:0004924//oncostatin-M receptor activity;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding","GO:0038165//oncostatin-M-mediated signaling pathway;GO:0008283//cell proliferation;GO:0010033//response to organic substance;GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell proliferation","K05057//oncostatin M receptor","gi|52851389|ref|NP_001005384.1|//oncostatin-M-specific receptor subunit beta precursor [Rattus norvegicus]"]
[null,310392,8894,13.4592826646906,4.72093921126329,1.51145570967177,"UP",0.0317861842891768,"Slc7a11","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0043232//intracellular non-membrane-bounded organelle","GO:0005275//amine transmembrane transporter activity","GO:0006865//amino acid transport;GO:0042221//response to chemical","K13869//solute carrier family 7 (L-type amino acid transporter), member 11","gi|164518939|ref|NP_001101143.2|//cystine/glutamate transporter [Rattus norvegicus]"]
[null,310444,3024,39.035513676519,85.9938527718432,-1.13944627863129,"DOWN",0.0237408034616183,"P2ry13","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0001608//G-protein coupled nucleotide receptor activity","GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway;GO:0071407//cellular response to organic cyclic compound;GO:0007194//negative regulation of adenylate cyclase activity;GO:0035588//G-protein coupled purinergic receptor signaling pathway","K08388//purinergic receptor P2Y, G protein-coupled, 13","gi|50811827|ref|NP_001002853.1|//P2Y purinoceptor 13 [Rattus norvegicus]"]
[null,310486,1360,738.341848031552,1576.82828415537,-1.09466472429574,"DOWN",{"v":5.12115752714247e-06,"d":"5.12E-06"},"Rarres1","GO:0031224//intrinsic component of membrane","NA","GO:0008283//cell proliferation","NA","gi|62339361|ref|NP_001014790.1|//retinoic acid receptor responder protein 1 precursor [Rattus norvegicus]"]
[null,310540,3626,35.3762055757022,91.2701201829654,-1.36736331710395,"DOWN",0.00592013822256866,"Fam198b","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane","NA","NA","NA","gi|40018578|ref|NP_954536.1|//protein FAM198B [Rattus norvegicus]"]
[null,310553,2717,44.0638544285642,117.057855229381,-1.40955414696295,"DOWN",0.00116513988520313,"Tlr2","GO:0031226//intrinsic component of plasma membrane;GO:0042995//cell projection;GO:0009897//external side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0035354//Toll-like receptor 1-Toll-like receptor 2 protein complex;GO:0031224//intrinsic component of membrane;GO:0044424//intracellular part;GO:0009986//cell surface;GO:0044297//cell body;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005794//Golgi apparatus;GO:0035355//Toll-like receptor 2-Toll-like receptor 6 protein complex;GO:0016021//integral component of membrane","GO:0004872//receptor activity;GO:0046982//protein heterodimerization activity;GO:0042834//peptidoglycan binding;GO:0046983//protein dimerization activity;GO:0042497//triacyl lipopeptide binding;GO:0035325//Toll-like receptor binding;GO:0001530//lipopolysaccharide binding;GO:0071723//lipopeptide binding;GO:0042498//diacyl lipopeptide binding;GO:0005539//glycosaminoglycan binding;GO:0004888//transmembrane signaling receptor activity;GO:0070891//lipoteichoic acid binding;GO:0008329//signaling pattern recognition receptor activity","GO:0032481//positive regulation of type I interferon production;GO:0002220//innate immune response activating cell surface receptor signaling pathway;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0034134//toll-like receptor 2 signaling pathway;GO:0001818//negative regulation of cytokine production;GO:0042495//detection of triacyl bacterial lipopeptide;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0070391//response to lipoteichoic acid;GO:0008285//negative regulation of cell proliferation;GO:0044126//regulation of growth of symbiont in host;GO:0002238//response to molecule of fungal origin;GO:0048545//response to steroid hormone;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:1904417//positive regulation of xenophagy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0010935//regulation of macrophage cytokine production;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0032494//response to peptidoglycan;GO:0007252//I-kappaB phosphorylation;GO:0032733//positive regulation of interleukin-10 production;GO:0032695//negative regulation of interleukin-12 production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0050729//positive regulation of inflammatory response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043434//response to peptide hormone;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:0071223//cellular response to lipoteichoic acid;GO:0002224//toll-like receptor signaling pathway;GO:0071224//cellular response to peptidoglycan;GO:0032700//negative regulation of interleukin-17 production;GO:0042892//chloramphenicol transport;GO:0002730//regulation of dendritic cell cytokine production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0050715//positive regulation of cytokine secretion;GO:0002687//positive regulation of leukocyte migration;GO:0032722//positive regulation of chemokine production;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0052063//induction by symbiont of defense-related host nitric oxide production;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0071221//cellular response to bacterial lipopeptide;GO:0052263//induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction;GO:0001774//microglial cell activation;GO:0033993//response to lipid;GO:0006468//protein phosphorylation;GO:0032757//positive regulation of interleukin-8 production;GO:0044130//negative regulation of growth of symbiont in host;GO:0070542//response to fatty acid;GO:0032755//positive regulation of interleukin-6 production;GO:0042891//antibiotic transport;GO:0032289//central nervous system myelin formation;GO:0042742//defense response to bacterium;GO:0052166//positive regulation by symbiont of host innate immune response;GO:0006691//leukotriene metabolic process;GO:0032741//positive regulation of interleukin-18 production;GO:0032735//positive regulation of interleukin-12 production;GO:0060907//positive regulation of macrophage cytokine production;GO:0032728//positive regulation of interferon-beta production;GO:0002374//cytokine secretion involved in immune response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0070340//detection of bacterial lipopeptide;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0042496//detection of diacyl bacterial lipopeptide;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K10159//toll-like receptor 2","gi|672042714|ref|XP_008759324.1|//PREDICTED: toll-like receptor 2 isoform X1 [Rattus norvegicus];gi|568922750|ref|XP_006501523.1|//PREDICTED: toll-like receptor 2 isoform X1 [Mus musculus]"]
[null,310693,1990,899.592037197878,2518.06838779796,-1.48497466933383,"DOWN",0.00317511999132894,"Cd5l","GO:0044464//cell part","GO:0004888//transmembrane signaling receptor activity","GO:0023052//signaling","K13912//deleted in malignant brain tumors 1 protein","gi|71043608|ref|NP_001020856.1|//CD5 antigen-like precursor [Rattus norvegicus]"]
[null,310791,3433,25.1494462898329,66.9292994905667,-1.41211127768406,"DOWN",0.00156947378962529,"Slc25a24","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane","GO:0046872//metal ion binding","GO:0006810//transport","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","gi|189011598|ref|NP_001121016.1|//calcium-binding mitochondrial carrier protein SCaMC-1 [Rattus norvegicus]"]
[null,310903,1896,11.3977274326671,32.6488811468251,-1.5182873551872,"DOWN",0.0160967261056752,"Adh6","GO:0044424//intracellular part;GO:0005739//mitochondrion","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046914//transition metal ion binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity","GO:0008152//metabolic process;GO:0042572//retinol metabolic process;GO:0032526//response to retinoic acid;GO:0055114//oxidation-reduction process;GO:0042573//retinoic acid metabolic process;GO:0048545//response to steroid hormone;GO:0033574//response to testosterone;GO:0006068//ethanol catabolic process;GO:0048149//behavioral response to ethanol","K13952//alcohol dehydrogenase 6 [EC:1.1.1.1]","gi|58865738|ref|NP_001012084.1|//alcohol dehydrogenase 6 [Rattus norvegicus];gi|564338964|ref|XP_006233434.1|//PREDICTED: alcohol dehydrogenase 6 isoform X1 [Rattus norvegicus]"]
[null,311112,2505,285.258747525991,136.764897625751,1.0605731352649,"UP",0.000102777876548034,"Fastkd1","GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion","GO:0044822//poly(A) RNA binding;GO:0032559//adenyl ribonucleotide binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity","GO:0045333//cellular respiration;GO:0006796//phosphate-containing compound metabolic process;GO:0015980//energy derivation by oxidation of organic compounds","K18190//FAST kinase domain-containing protein 2","gi|300795436|ref|NP_001178667.1|//FAST kinase domain-containing protein 1 [Rattus norvegicus];gi|149022167|gb|EDL79061.1|//similar to RIKEN cDNA 5330408N05 gene (predicted) [Rattus norvegicus]"]
[null,311252,2834,63.2601142474386,138.003100828005,-1.12533261719227,"DOWN",0.00323158992064629,"Pamr1","GO:0005576//extracellular region","GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0006508//proteolysis;GO:0019538//protein metabolic process","K13047//tolloid-like protein 2 [EC:3.4.24.-];K05502//bone morphogenetic protein 1 [EC:3.4.24.19]","gi|157820531|ref|NP_001101225.1|//inactive serine protease PAMR1 precursor [Rattus norvegicus] ;gi|672046405|ref|XP_008760283.1|//PREDICTED: inactive serine protease PAMR1 isoform X1 [Rattus norvegicus]"]
[null,311341,5335,559.561973715632,260.75620717231,1.10159632847395,"UP",0.00062372336446526,"Pla2g4b","GO:0005829//cytosol","GO:0004622//lysophospholipase activity;GO:0047498//calcium-dependent phospholipase A2 activity","GO:0046475//glycerophospholipid catabolic process","K16342//cytosolic phospholipase A2 [EC:3.1.1.4]","gi|167900429|ref|NP_001101234.2|//cytosolic phospholipase A2 beta [Rattus norvegicus];gi|205829269|sp|P0C871.1|PA24B_MOUSE//RecName: Full=Cytosolic phospholipase A2 beta; Short=cPLA2-beta; AltName: Full=Phospholipase A2 group IVB;gi|167900427|ref|NP_663353.3|//cytosolic phospholipase A2 beta [Mus musculus]"]
[null,311428,1499,342.535690391203,164.945142892332,1.05426802126328,"UP",0.0157849434027752,"RGD1311739","NA","NA","NA","NA","gi|71043764|ref|NP_001020862.1|//UPF0687 protein C20orf27 homolog [Rattus norvegicus];gi|148696358|gb|EDL28305.1|//RIKEN cDNA 1700037H04, isoform CRA_d, partial [Mus musculus]"]
[null,311437,3428,26.7589841879652,69.1210206287914,-1.36910117013412,"DOWN",0.00486178828100817,"Rassf2","GO:0043231//intracellular membrane-bounded organelle","GO:0005488//binding","GO:0023052//signaling;GO:0009987//cellular process","K09851//Ras association domain-containing protein 2/4","gi|79749367|ref|NP_001032173.1|//ras association domain-containing protein 2 [Rattus norvegicus]"]
[null,311569,2878,649.347822119145,321.445482934511,1.01441738493323,"UP",0.0128301641725523,"Acss2","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0044444//cytoplasmic part;GO:0005737//cytoplasm","GO:0003987//acetate-CoA ligase activity;GO:0005524//ATP binding;GO:0032559//adenyl ribonucleotide binding;GO:0016405//CoA-ligase activity","GO:0006085//acetyl-CoA biosynthetic process;GO:0019413//acetate biosynthetic process;GO:0019542//propionate biosynthetic process;GO:0006084//acetyl-CoA metabolic process;GO:0006083//acetate metabolic process;GO:0019541//propionate metabolic process;GO:0006629//lipid metabolic process","K01895//acetyl-CoA synthetase [EC:6.2.1.1]","gi|564343781|ref|XP_006235383.1|//PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [Rattus norvegicus];gi|157823265|ref|NP_001101263.1|//acetyl-coenzyme A synthetase, cytoplasmic [Rattus norvegicus] "]
[null,311647,3499,216.194909556969,469.069004803553,-1.11746761908779,"DOWN",0.00126718652108269,"Prex1","GO:0005622//intracellular","GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0035023//regulation of Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity","K12365//phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein","gi|208973288|ref|NP_001129190.1|//phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein [Rattus norvegicus];gi|149042860|gb|EDL96434.1|//similar to P-Rex1 (predicted) [Rattus norvegicus]"]
[null,311713,2621,131.954709545559,51.8449381159485,1.34776779886655,"UP",0.000735762024871956,"Mrgbp","GO:0000123//histone acetyltransferase complex","NA","GO:0050789//regulation of biological process;GO:0006325//chromatin organization","K11343//MRG-binding protein","gi|149034020|gb|EDL88803.1|//rCG38412, isoform CRA_e [Rattus norvegicus];gi|149034017|gb|EDL88800.1|//rCG38412, isoform CRA_b [Rattus norvegicus]"]
[null,311748,1369,199.587200959128,98.2546314439359,1.02242188849528,"UP",0.00293962389649443,"Metap1d","GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0070006//metalloaminopeptidase activity","GO:0006508//proteolysis;GO:0019538//protein metabolic process;GO:0070084//protein initiator methionine removal","K01265//methionyl aminopeptidase [EC:3.4.11.18]","gi|189181753|ref|NP_001101282.2|//methionine aminopeptidase 1D, mitochondrial [Rattus norvegicus] "]
[null,311849,2961,2895.38081209878,1206.18731199164,1.2632991451999,"UP",0.0157835596468495,"Crat","GO:0005783//endoplasmic reticulum;GO:0005743//mitochondrial inner membrane;GO:0042579//microbody;GO:0005777//peroxisome;GO:0019866//organelle inner membrane","GO:0004092//carnitine O-acetyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0005102//receptor binding","GO:0006810//transport;GO:0006635//fatty acid beta-oxidation;GO:0006631//fatty acid metabolic process;GO:0019254//carnitine metabolic process, CoA-linked;GO:0051234//establishment of localization","K00624//carnitine O-acetyltransferase [EC:2.3.1.7]","gi|51854229|ref|NP_001004085.1|//carnitine O-acetyltransferase [Rattus norvegicus];gi|947274649|ref|XP_014445434.1|//PREDICTED: carnitine O-acetyltransferase [Tupaia chinensis];gi|50513719|pdb|1T7Q|A//Chain A, Crystal Structure Of The F565a Mutant Of Murine Carnitine Acetyltransferase In Complex With Carnitine And Coa;gi|589941528|ref|XP_006983486.1|//PREDICTED: carnitine O-acetyltransferase [Peromyscus maniculatus bairdii]"]
[null,311860,5406,420.407621993751,209.116996356557,1.00747850130706,"UP",0.00416008528735193,"Abl1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0043232//intracellular non-membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0031981//nuclear lumen;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion;GO:0045202//synapse;GO:0005654//nucleoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0001726//ruffle;GO:0044444//cytoplasmic part","GO:0051015//actin filament binding;GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0017124//SH3 domain binding;GO:0070064//proline-rich region binding;GO:0030145//manganese ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0046914//transition metal ion binding;GO:0070097//delta-catenin binding;GO:0005080//protein kinase C binding;GO:0019904//protein domain specific binding;GO:0008022//protein C-terminus binding;GO:0032559//adenyl ribonucleotide binding;GO:0019905//syntaxin binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:0002333//transitional one stage B cell differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0006914//autophagy;GO:0060020//Bergmann glial cell differentiation;GO:0030041//actin filament polymerization;GO:0006909//phagocytosis;GO:0006975//DNA damage induced protein phosphorylation;GO:0045930//negative regulation of mitotic cell cycle;GO:0034446//substrate adhesion-dependent cell spreading;GO:0048146//positive regulation of fibroblast proliferation;GO:1904528//positive regulation of microtubule binding;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0090135//actin filament branching;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0006915//apoptotic process;GO:1900275//negative regulation of phospholipase C activity;GO:0071871//response to epinephrine;GO:0002322//B cell proliferation involved in immune response;GO:0033690//positive regulation of osteoblast proliferation;GO:0021587//cerebellum morphogenesis;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0001922//B-1 B cell homeostasis;GO:0031113//regulation of microtubule polymerization;GO:0048536//spleen development;GO:0051353//positive regulation of oxidoreductase activity;GO:1903210//glomerular visceral epithelial cell apoptotic process;GO:0050853//B cell receptor signaling pathway;GO:0046632//alpha-beta T cell differentiation;GO:0043525//positive regulation of neuron apoptotic process;GO:0050798//activated T cell proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:1990051//activation of protein kinase C activity;GO:0006469//negative regulation of protein kinase activity;GO:1904531//positive regulation of actin filament binding;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:1902715//positive regulation of interferon-gamma secretion;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:2001020//regulation of response to DNA damage stimulus;GO:0032956//regulation of actin cytoskeleton organization;GO:0022408//negative regulation of cell-cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0045087//innate immune response;GO:1900006//positive regulation of dendrite development;GO:0042493//response to drug;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:1900042//positive regulation of interleukin-2 secretion;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0042770//signal transduction in response to DNA damage;GO:0007010//cytoskeleton organization;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:2000773//negative regulation of cellular senescence;GO:0030514//negative regulation of BMP signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0048668//collateral sprouting;GO:1903055//positive regulation of extracellular matrix organization;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043085//positive regulation of catalytic activity;GO:0006281//DNA repair;GO:0048538//thymus development;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030516//regulation of axon extension;GO:0030035//microspike assembly;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008306//associative learning;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007049//cell cycle","K06619//abelson tyrosine-protein kinase 1 [EC:2.7.10.2]","gi|291167784|ref|NP_001094320.1|//tyrosine-protein kinase ABL1 [Rattus norvegicus] ;gi|392346207|ref|XP_003749487.1|//PREDICTED: tyrosine-protein kinase ABL1 isoform X2 [Rattus norvegicus]"]
[null,312102,1448,268.055212632429,803.026806078817,-1.58291795739587,"DOWN",{"v":7.47947547309846e-07,"d":"7.48E-07"},"Vsig4","NA","NA","GO:0042098//T cell proliferation;GO:0001818//negative regulation of cytokine production","K19822//V-set and immunoglobulin domain-containing protein 4","gi|68163443|ref|NP_001020175.1|//V-set and immunoglobulin domain-containing protein 4 precursor [Rattus norvegicus]"]
[null,312477,1757,25.7489904735426,51.9647380311098,-1.01301710810361,"DOWN",0.0327174143640253,"Dok1","GO:0044444//cytoplasmic part","GO:0005102//receptor binding","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007264//small GTPase mediated signal transduction","K14752//docking protein 1","gi|70794756|ref|NP_001020587.1|//docking protein 1 [Rattus norvegicus]"]
[null,312503,2338,285.887225672573,137.978988762171,1.05099756507652,"UP",0.00448754160403842,"Smyd5","NA","NA","NA","K11426//SET and MYND domain-containing protein","gi|157823305|ref|NP_001101340.1|//SET and MYND domain-containing protein 5 [Rattus norvegicus] ;gi|524936098|ref|XP_005071127.1|//PREDICTED: SET and MYND domain-containing protein 5 [Mesocricetus auratus]"]
[null,312701,6267,858.047488467123,2631.58623043516,-1.61680326836206,"DOWN",{"v":1.93512755193103e-14,"d":"1.94E-14"},"Cd163","GO:0016020//membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005044//scavenger receptor activity;GO:0004888//transmembrane signaling receptor activity","GO:0006953//acute-phase response;GO:0002526//acute inflammatory response","K06545//CD163 antigen","gi|157823809|ref|NP_001101357.1|//scavenger receptor cysteine-rich type 1 protein M130 [Rattus norvegicus] "]
[null,313245,1588,128.54760256094,64.2634132028902,1.00023319049042,"UP",0.0250157694741736,"Polr1e","GO:0031981//nuclear lumen;GO:0044459//plasma membrane part","GO:0034062//5'-3' RNA polymerase activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K03005//DNA-directed RNA polymerase I subunit RPA49","gi|157817813|ref|NP_001101408.1|//DNA-directed RNA polymerase I subunit RPA49 [Rattus norvegicus]"]
[null,313254,2276,60.3532068904628,162.865181122425,-1.43217586739546,"DOWN",0.00107506951287625,"Kif12","GO:0070062//extracellular exosome;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0032559//adenyl ribonucleotide binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0007018//microtubule-based movement;GO:0007017//microtubule-based process","K10399//kinesin family member 12","gi|564351318|ref|XP_006238315.1|//PREDICTED: kinesin-like protein KIF12 isoform X1 [Rattus norvegicus];gi|199560168|ref|NP_001012102.2|//kinesin-like protein KIF12 [Rattus norvegicus]"]
[null,313488,4204,43.7606602897488,89.8988117437888,-1.03866754011402,"DOWN",0.0384482926947068,"Reck","GO:0031224//intrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane","GO:0008191//metalloendopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0045747//positive regulation of Notch signaling pathway;GO:0001568//blood vessel development;GO:0030336//negative regulation of cell migration;GO:0043062//extracellular structure organization;GO:0001955//blood vessel maturation;GO:0007566//embryo implantation;GO:0035115//embryonic forelimb morphogenesis;GO:0030198//extracellular matrix organization;GO:1904684//negative regulation of metalloendopeptidase activity","K17461//reversion-inducing-cysteine-rich protein with kazal motifs","gi|157818137|ref|NP_001101424.1|//reversion-inducing cysteine-rich protein with Kazal motifs precursor [Rattus norvegicus];gi|149045778|gb|EDL98778.1|//rCG54895, isoform CRA_a [Rattus norvegicus]"]
[null,313589,1855,10.2954324396926,26.4679816188006,-1.36224375390747,"DOWN",0.0313772008194697,"Rspo1","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part","GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding","GO:0030177//positive regulation of Wnt signaling pathway;GO:0031323//regulation of cellular metabolic process","K19471//R-spondin-1","gi|880956975|ref|XP_005084423.2|//PREDICTED: R-spondin-1 [Mesocricetus auratus];gi|157818717|ref|NP_001101450.1|//R-spondin-1 precursor [Rattus norvegicus] "]
[null,313840,2256,781.128058364702,350.660100180686,1.15548580056851,"UP",0.00192315758730131,"Rmdn2","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0000922//spindle pole;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","NA","gi|564354652|ref|XP_006239695.1|//PREDICTED: regulator of microtubule dynamics protein 2 isoform X2 [Rattus norvegicus];gi|149050616|gb|EDM02789.1|//similar to hypothetical protein FLJ32954 [Rattus norvegicus];gi|564354654|ref|XP_006239696.1|//PREDICTED: regulator of microtubule dynamics protein 2 isoform X3 [Rattus norvegicus]"]
[null,313917,1387,949.020729942415,361.965875776823,1.3905859070303,"UP",0.00144451443136094,"Abhd1","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane","GO:0052689//carboxylic ester hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds","NA","K13696//abhydrolase domain-containing protein 1/3","gi|56606090|ref|NP_001008520.1|//protein ABHD1 [Rattus norvegicus]"]
[null,314304,2989,1999.6167287996,608.694085757957,1.71593424840784,"UP",0.00269211185854373,"Acot3","GO:0005829//cytosol;GO:0042579//microbody","GO:0052689//carboxylic ester hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0005488//binding","GO:0006732//coenzyme metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006629//lipid metabolic process","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","gi|955508897|ref|XP_014639875.1|//PREDICTED: acyl-coenzyme A thioesterase 1 [Ceratotherium simum simum];gi|157820563|ref|NP_001101511.1|//acyl-CoA thioesterase 3 [Rattus norvegicus];gi|512950221|ref|XP_004837549.1|//PREDICTED: LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 3 [Heterocephalus glaber];gi|348573346|ref|XP_003472452.1|//PREDICTED: acyl-coenzyme A thioesterase 1 [Cavia porcellus];gi|531998330|ref|XP_005343709.1|//PREDICTED: acyl-coenzyme A thioesterase 1 [Microtus ochrogaster]"]
[null,314386,3115,22.3530195696485,52.5212058716543,-1.23243030866369,"DOWN",0.0225005678039706,"Gpr68","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity","GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway","K08408//G protein-coupled receptor 68","gi|157820739|ref|NP_001101519.1|//ovarian cancer G-protein coupled receptor 1 [Rattus norvegicus]"]
[null,314616,2387,5.95783305686042,20.3378178672428,-1.77130529066231,"DOWN",0.00603214986203107,"Arid3a","GO:0043231//intracellular membrane-bounded organelle","GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K11653//AT-rich interactive domain-containing protein 1;K14829//pre-rRNA-processing protein IPI3","gi|224591422|ref|NP_001101536.2|//AT-rich interactive domain-containing protein 3A [Rattus norvegicus]"]
[null,314654,3818,102.211902003599,228.647749570405,-1.16156351989956,"DOWN",0.00398675402690222,"Myo1f","GO:0005884//actin filament","GO:0032559//adenyl ribonucleotide binding;GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity","GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0002283//neutrophil activation involved in immune response;GO:0031347//regulation of defense response;GO:0002444//myeloid leukocyte mediated immunity","K10356//myosin I","gi|157821107|ref|NP_001101546.1|//myosin-If [Rattus norvegicus] "]
[null,314855,5450,32.3266768812452,85.6608571459551,-1.40591090442645,"DOWN",0.000807649768804921,"Cpm","GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane","GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity","GO:0032502//developmental process;GO:0019538//protein metabolic process","K01296//carboxypeptidase M [EC:3.4.17.12]","gi|157821719|ref|NP_001101568.1|//carboxypeptidase M precursor [Rattus norvegicus] "]
[null,314981,3974,509.651213169022,1150.6558522798,-1.17487424309922,"DOWN",0.0114055140259636,"Col14a1","GO:0031012//extracellular matrix","NA","NA","K08133//collagen, type XIV, alpha;K16630//collagen, type XXII, alpha","gi|970731213|ref|XP_015100611.1|//PREDICTED: collagen alpha-1(XXII) chain, partial [Vicugna pacos];gi|194474004|ref|NP_001124020.1|//collagen alpha-1(XIV) chain precursor [Rattus norvegicus] "]
[null,315164,873,253.469835078203,124.515425160969,1.02548958865694,"UP",0.0143454120942548,"Cenpm","GO:0043231//intracellular membrane-bounded organelle;GO:0000776//kinetochore;GO:0044444//cytoplasmic part","NA","GO:0007067//mitotic nuclear division","K11505//centromere protein M","gi|564361196|ref|XP_006242148.1|//PREDICTED: centromere protein M isoform X2 [Rattus norvegicus]"]
[null,315174,7712,25.0834549227394,143.896935497123,-2.52022788843943,"DOWN",0.00023690844112824,"Scube1","NA","NA","NA","K06825//fibrillin 1","gi|149065746|gb|EDM15619.1|//signal peptide, CUB domain, EGF-like 1 [Rattus norvegicus];gi|103472029|ref|NP_073560.2|//signal peptide, CUB and EGF-like domain-containing protein 1 isoform b precursor [Mus musculus];gi|199561863|ref|NP_001128356.1|//signal peptide, CUB and EGF-like domain-containing protein 1 precursor [Rattus norvegicus]"]
[null,315191,2787,20.0573126999333,66.9763978190847,-1.73952446081064,"DOWN",0.00855925476021824,"Fbln1","GO:0005578//proteinaceous extracellular matrix","GO:0005488//binding;GO:0008047//enzyme activator activity","GO:0043062//extracellular structure organization","K17307//fibulin 1/2","gi|189011620|ref|NP_001121019.1|//fibulin-1 precursor [Rattus norvegicus] "]
[null,315219,2503,3077.33069331431,929.927448630394,1.72648941649313,"UP",{"v":1.10441915989801e-08,"d":"1.10E-08"},"Tymp","GO:0005829//cytosol;GO:0044444//cytoplasmic part","GO:0070851//growth factor receptor binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016154//pyrimidine-nucleoside phosphorylase activity;GO:0009032//thymidine phosphorylase activity;GO:0016758//transferase activity, transferring hexosyl groups;GO:0004645//phosphorylase activity","GO:0042221//response to chemical;GO:0006220//pyrimidine nucleotide metabolic process;GO:0008655//pyrimidine-containing compound salvage;GO:0006213//pyrimidine nucleoside metabolic process;GO:0006259//DNA metabolic process;GO:0007005//mitochondrion organization;GO:0009117//nucleotide metabolic process;GO:0048869//cellular developmental process;GO:0009112//nucleobase metabolic process;GO:0032501//multicellular organismal process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0048646//anatomical structure formation involved in morphogenesis","K07152//protein SCO1/2;K00758//thymidine phosphorylase [EC:2.4.2.4]","gi|672060036|ref|XP_008763952.1|//PREDICTED: thymidine phosphorylase isoform X1 [Rattus norvegicus];gi|58865814|ref|NP_001012122.1|//thymidine phosphorylase [Rattus norvegicus];gi|672060043|ref|XP_008763955.1|//PREDICTED: thymidine phosphorylase isoform X5 [Rattus norvegicus]"]
[null,315323,2031,7.32615472792066,22.3608050060479,-1.60984405113056,"DOWN",0.0178609811674445,"Krt4","GO:0005882//intermediate filament","GO:0046983//protein dimerization activity","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0008285//negative regulation of cell proliferation","K07605//type II keratin, basic","gi|57012360|ref|NP_001008806.1|//keratin, type II cytoskeletal 4 [Rattus norvegicus];gi|625227879|ref|XP_003515002.2|//PREDICTED: keratin, type II cytoskeletal 4 [Cricetulus griseus]"]
[null,315348,4947,134.256443261587,314.242168120389,-1.22688546072822,"DOWN",0.000495348936243398,"Nckap1l","GO:0043234//protein complex","GO:0005515//protein binding;GO:0019887//protein kinase regulator activity","GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0033627//cell adhesion mediated by integrin;GO:0050766//positive regulation of phagocytosis;GO:0001932//regulation of protein phosphorylation;GO:0007163//establishment or maintenance of cell polarity;GO:0001818//negative regulation of cytokine production;GO:0045582//positive regulation of T cell differentiation;GO:0030041//actin filament polymerization;GO:0030888//regulation of B cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0045639//positive regulation of myeloid cell differentiation;GO:0006915//apoptotic process;GO:0043376//regulation of CD8-positive, alpha-beta T cell differentiation;GO:0043370//regulation of CD4-positive, alpha-beta T cell differentiation;GO:0042098//T cell proliferation;GO:0002260//lymphocyte homeostasis;GO:0050851//antigen receptor-mediated signaling pathway","K05750//NCK-associated protein 1","gi|524926352|ref|XP_005067414.1|//PREDICTED: nck-associated protein 1-like [Mesocricetus auratus];gi|157824172|ref|NP_001101589.1|//nck-associated protein 1-like [Rattus norvegicus] ;gi|672060100|ref|XP_008763975.1|//PREDICTED: nck-associated protein 1-like isoform X1 [Rattus norvegicus]"]
[null,315594,1743,1013.50525715325,2452.53714233321,-1.27492141320918,"DOWN",0.000295743740881367,"Oaf","NA","NA","NA","K09364//POU domain transcription factor, class 2","gi|62078913|ref|NP_001014112.1|//out at first protein homolog precursor [Rattus norvegicus]"]
[null,315714,2491,16.7729130037366,42.7778748628808,-1.35073154549966,"DOWN",0.00870087436981026,"Loxl1","GO:0031012//extracellular matrix","GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0046914//transition metal ion binding","GO:0008152//metabolic process","K14678//lysyl oxidase-like protein 1 [EC:1.4.3.-]","gi|149041833|gb|EDL95674.1|//rCG57920, isoform CRA_b [Rattus norvegicus]"]
[null,316137,3228,223.265297214132,533.349860579002,-1.25632317943871,"DOWN",0.000163291276401806,"Adgre1","GO:0031224//intrinsic component of membrane;GO:0009986//cell surface","GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K04591//egf-like module containing, mucin-like, hormone receptor-like 1","gi|56090594|ref|NP_001007558.1|//adhesion G protein-coupled receptor E2 precursor [Rattus norvegicus]"]
[null,316256,4350,230.101787576967,754.029288477553,-1.71234837126826,"DOWN",0.000780125062711711,"Tnfrsf21","GO:0031224//intrinsic component of membrane;GO:0044424//intracellular part;GO:0043005//neuron projection","GO:0004871//signal transducer activity","GO:0006915//apoptotic process","K05157//tumor necrosis factor receptor superfamily member 21","gi|157817151|ref|NP_001101677.1|//tumor necrosis factor receptor superfamily member 21 precursor [Rattus norvegicus]"]
[null,316351,4027,145.540108122213,43.8844214647389,1.72963599430777,"UP",0.0015043366001265,"Npas2","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0060089//molecular transducer activity;GO:0031072//heat shock protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0046872//metal ion binding;GO:0003700//transcription factor activity, sequence-specific DNA binding","GO:0042752//regulation of circadian rhythm;GO:0051775//response to redox state;GO:0007626//locomotory behavior;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0023052//signaling;GO:0045739//positive regulation of DNA repair;GO:0045475//locomotor rhythm;GO:0032922//circadian regulation of gene expression;GO:0060548//negative regulation of cell death;GO:0048512//circadian behavior;GO:0042745//circadian sleep/wake cycle","K09026//neuronal PAS domain-containing protein 2","gi|210032658|ref|NP_001101684.2|//neuronal PAS domain-containing protein 2 [Rattus norvegicus] "]
[null,316384,2148,51.7192681139085,143.061857836807,-1.46786531731578,"DOWN",0.00273392189596293,"Sdpr","GO:0044459//plasma membrane part;GO:0044444//cytoplasmic part","GO:0005543//phospholipid binding","GO:0006357//regulation of transcription from RNA polymerase II promoter","K19387//polymerase I and transcript release factor","gi|56090257|ref|NP_001007713.1|//serum deprivation-response protein [Rattus norvegicus]"]
[null,316583,2555,29.1769208780749,363.846612697041,-3.64043083494453,"DOWN",{"v":2.14413513903593e-18,"d":"2.14E-18"},"B3gnt7","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system","GO:0008194//UDP-glycosyltransferase activity;GO:0016758//transferase activity, transferring hexosyl groups","GO:0006464//cellular protein modification process","K09664//beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]","gi|58865838|ref|NP_001012134.1|//UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Rattus norvegicus]"]
[null,316602,6666,215.660791225491,89.2890989668231,1.2722079504094,"UP",0.0113487874660401,"Hjurp","GO:0031981//nuclear lumen;GO:0005730//nucleolus;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0005515//protein binding;GO:0042802//identical protein binding","GO:0007059//chromosome segregation;GO:0043254//regulation of protein complex assembly;GO:0043486//histone exchange;GO:0031497//chromatin assembly;GO:0051101//regulation of DNA binding;GO:0034080//CENP-A containing nucleosome assembly","NA","gi|564369492|ref|XP_006245455.1|//PREDICTED: Holliday junction recognition protein isoform X1 [Rattus norvegicus];gi|300796955|ref|NP_001178742.1|//Holliday junction recognition protein [Rattus norvegicus]"]
[null,317371,1534,35.2424924342621,71.7984855261059,-1.02663745428396,"DOWN",0.025462367600729,"Was","GO:0012505//endomembrane system;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0012506//vesicle membrane;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0017124//SH3 domain binding;GO:0030695//GTPase regulator activity;GO:0019901//protein kinase binding","GO:0042110//T cell activation;GO:0016197//endosomal transport;GO:0030048//actin filament-based movement;GO:0002625//regulation of T cell antigen processing and presentation;GO:0065003//macromolecular complex assembly;GO:0016192//vesicle-mediated transport;GO:0019222//regulation of metabolic process;GO:0008154//actin polymerization or depolymerization;GO:0046649//lymphocyte activation;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:2000146//negative regulation of cell motility","K05747//Wiskott-Aldrich syndrome protein","gi|157816991|ref|NP_001101718.1|//wiskott-Aldrich syndrome protein [Rattus norvegicus] ;gi|165971260|gb|AAI58678.1|//Was protein [Rattus norvegicus]"]
[null,317382,3732,45.4851393162191,14.4155612785735,1.65776826184909,"UP",0.0162008860974142,"Foxp3","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005737//cytoplasm","GO:0051525//NFAT protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0046983//protein dimerization activity;GO:0003712//transcription cofactor activity;GO:0043565//sequence-specific DNA binding;GO:0001047//core promoter binding;GO:0042826//histone deacetylase binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0035035//histone acetyltransferase binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0042036//negative regulation of cytokine biosynthetic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0002262//myeloid cell homeostasis;GO:0002513//tolerance induction to self antigen;GO:0042130//negative regulation of T cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0031064//negative regulation of histone deacetylation;GO:0050710//negative regulation of cytokine secretion;GO:0032753//positive regulation of interleukin-4 production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0002725//negative regulation of T cell cytokine production;GO:0032792//negative regulation of CREB transcription factor activity;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0035067//negative regulation of histone acetylation;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:0032714//negative regulation of interleukin-5 production;GO:0002544//chronic inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002666//positive regulation of T cell tolerance induction;GO:0001782//B cell homeostasis;GO:0016575//histone deacetylation;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0031348//negative regulation of defense response;GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0002669//positive regulation of T cell anergy;GO:0002362//CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment;GO:0032693//negative regulation of interleukin-10 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0032905//transforming growth factor beta1 production;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050707//regulation of cytokine secretion;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0002369//T cell cytokine production;GO:0002677//negative regulation of chronic inflammatory response;GO:0002851//positive regulation of peripheral T cell tolerance induction;GO:0045582//positive regulation of T cell differentiation;GO:0045829//negative regulation of isotype switching;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0035066//positive regulation of histone acetylation;GO:0002458//peripheral T cell tolerance induction;GO:0033080//immature T cell proliferation in thymus;GO:0032713//negative regulation of interleukin-4 production;GO:0050852//T cell receptor signaling pathway;GO:0016573//histone acetylation;GO:0032700//negative regulation of interleukin-17 production;GO:0022037//metencephalon development;GO:0002260//lymphocyte homeostasis;GO:0032831//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0009615//response to virus","K10163//forkhead box P3","gi|294979130|dbj|BAJ05811.1|//forkhead box P3 isoform 2 [Rattus norvegicus]"]
[null,317468,4221,34.4096930281564,104.184223005178,-1.59824989477546,"DOWN",0.00267564859876993,"Tlr7","GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0000323//lytic vacuole","GO:0003723//RNA binding;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0003727//single-stranded RNA binding","GO:0009612//response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0052166//positive regulation by symbiont of host innate immune response;GO:0002252//immune effector process;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0001819//positive regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0001774//microglial cell activation","K05404//toll-like receptor 7","gi|589920338|ref|XP_006973242.1|//PREDICTED: toll-like receptor 7 [Peromyscus maniculatus bairdii];gi|147900684|ref|NP_001091051.1|//toll-like receptor 7 [Rattus norvegicus]"]
[null,338477,2772,33.9543291387623,102.90594664086,-1.59965892056399,"DOWN",0.00140330156018918,"Sla","GO:0043231//intracellular membrane-bounded organelle;GO:0005768//endosome;GO:0016323//basolateral plasma membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","GO:0016785//transferase activity, transferring selenium-containing groups;GO:0052693//epoxyqueuosine reductase activity;GO:0043826//sulfur oxygenase reductase activity;GO:0000049//tRNA binding;GO:0043883//malolactic enzyme activity;GO:0005488//binding;GO:0043738//reduced coenzyme F420 dehydrogenase activity;GO:0008748//N-ethylmaleimide reductase activity;GO:0005515//protein binding;GO:0005507//copper ion binding;GO:0004322//ferroxidase activity;GO:0043914//NADPH:sulfur oxidoreductase activity;GO:0008198//ferrous iron binding","GO:0006879//cellular iron ion homeostasis;GO:0006826//iron ion transport;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process;GO:0001514//selenocysteine incorporation;GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport;GO:0030218//erythrocyte differentiation","K08893//hemopoietic cell kinase [EC:2.7.10.2]","gi|30017421|ref|NP_835198.1|//src-like-adapter [Rattus norvegicus];gi|149066283|gb|EDM16156.1|//src-like adaptor, isoform CRA_b [Rattus norvegicus]"]
[null,353250,1083,9.7901260588587,27.0794985965407,-1.4678016848687,"DOWN",0.0132968823981664,"Niacr1","GO:0031224//intrinsic component of membrane","GO:0016502//nucleotide receptor activity;GO:0032561//guanyl ribonucleotide binding;GO:0004930//G-protein coupled receptor activity","GO:0046887//positive regulation of hormone secretion;GO:0009895//negative regulation of catabolic process;GO:0001781//neutrophil apoptotic process;GO:0007166//cell surface receptor signaling pathway","K08402//G protein-coupled receptor 109","gi|31324560|ref|NP_852141.1|//hydroxycarboxylic acid receptor 2 [Rattus norvegicus]"]
[null,353305,3982,102.647822048319,260.634404368649,-1.34432451860712,"DOWN",0.000126211698563753,"Tbx3","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0003677//DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding","GO:0030540//female genitalia development;GO:0060412//ventricular septum morphogenesis;GO:0003143//embryonic heart tube morphogenesis;GO:0048732//gland development;GO:0001568//blood vessel development;GO:0030857//negative regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0003167//atrioventricular bundle cell differentiation;GO:2000648//positive regulation of stem cell proliferation;GO:0060788//ectodermal placode formation;GO:0021761//limbic system development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0046545//development of primary female sexual characteristics;GO:0000578//embryonic axis specification;GO:0032274//gonadotropin secretion;GO:0035116//embryonic hindlimb morphogenesis;GO:0045661//regulation of myoblast differentiation;GO:0043066//negative regulation of apoptotic process;GO:0003151//outflow tract morphogenesis;GO:0010159//specification of animal organ position;GO:0045662//negative regulation of myoblast differentiation;GO:0030900//forebrain development;GO:0019827//stem cell population maintenance;GO:0051726//regulation of cell cycle;GO:0008595//anterior/posterior axis specification, embryo;GO:0045787//positive regulation of cell cycle;GO:0060931//sinoatrial node cell development;GO:0060923//cardiac muscle cell fate commitment;GO:0060596//mammary placode formation;GO:0006355//regulation of transcription, DNA-templated;GO:0035051//cardiocyte differentiation;GO:0003002//regionalization;GO:0042733//embryonic digit morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001944//vasculature development;GO:0046884//follicle-stimulating hormone secretion;GO:0030539//male genitalia development;GO:0008283//cell proliferation;GO:0090398//cellular senescence;GO:0060021//palate development;GO:0048332//mesoderm morphogenesis;GO:0001701//in utero embryonic development;GO:0007568//aging;GO:0035115//embryonic forelimb morphogenesis;GO:0001947//heart looping;GO:0046546//development of primary male sexual characteristics;GO:0032275//luteinizing hormone secretion;GO:0001501//skeletal system development","K10177//T-box protein 3","gi|31745146|ref|NP_853669.1|//T-box transcription factor TBX3 [Rattus norvegicus];gi|564379570|ref|XP_006249480.1|//PREDICTED: T-box transcription factor TBX3 isoform X2 [Rattus norvegicus]"]
[null,359726,4268,30.6443296082894,74.9380147534196,-1.29007761454314,"DOWN",0.00490501374063159,"Rnasel","GO:0034399//nuclear periphery;GO:0005739//mitochondrion;GO:0016363//nuclear matrix","GO:0003723//RNA binding;GO:0016443//bidentate ribonuclease III activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004521//endoribonuclease activity;GO:0046872//metal ion binding;GO:0043169//cation binding;GO:0032559//adenyl ribonucleotide binding;GO:0004672//protein kinase activity;GO:0043021//ribonucleoprotein complex binding;GO:0004540//ribonuclease activity;GO:0019843//rRNA binding","GO:0006396//RNA processing;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0006397//mRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0006464//cellular protein modification process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0045071//negative regulation of viral genome replication;GO:0051707//response to other organism;GO:0043488//regulation of mRNA stability","K01165//ribonuclease L","gi|149058381|gb|EDM09538.1|//ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) [Rattus norvegicus];gi|564381084|ref|XP_006250066.1|//PREDICTED: 2-5A-dependent ribonuclease isoform X2 [Rattus norvegicus];gi|32996725|ref|NP_872614.1|//2-5A-dependent ribonuclease [Rattus norvegicus]"]
[null,360202,3131,5.38477192563278,14.1810354847696,-1.39700573534889,"DOWN",0.0322192358869918,"Ston1","GO:0030119//AP-type membrane coat adaptor complex","NA","GO:0006897//endocytosis","K20067//stonin-1/2","gi|281427176|ref|NP_891999.2|//stonin-1 [Rattus norvegicus]"]
[null,360228,384,1403.24080696468,4352.55209788996,-1.63309895850443,"DOWN",0.00167446359478908,"Wfdc21","GO:0044421//extracellular region part","GO:0004857//enzyme inhibitor activity;GO:0008047//enzyme activator activity","GO:0045444//fat cell differentiation;GO:0034097//response to cytokine;GO:0002237//response to molecule of bacterial origin","NA","gi|33438173|dbj|BAC81506.1|//WDNM1-like protein [Rattus norvegicus]"]
[null,360482,2136,92.708103918018,43.5531691313046,1.08991775519649,"UP",0.031545142499011,"Tfap4","GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding","GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0051414//response to cortisol;GO:0051100//negative regulation of binding;GO:0065003//macromolecular complex assembly;GO:0007050//cell cycle arrest;GO:0006915//apoptotic process;GO:0000084//mitotic S phase;GO:0043921//modulation by host of viral transcription;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0032897//negative regulation of viral transcription;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K09108//transcription factor AP-4","gi|655889180|ref|XP_008247816.1|//PREDICTED: LOW QUALITY PROTEIN: transcription factor AP-4 [Oryctolagus cuniculus]"]
[null,360569,1479,160.040082057311,74.4794036490587,1.10351984700329,"UP",0.00520443925451333,"Rnmtl1","GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion","GO:0043803//hydroxyneurosporene-O-methyltransferase activity;GO:0008168//methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0034541//dimethylarsinite methyltransferase activity;GO:0052665//tRNA (uracil-2'-O-)-methyltransferase activity;GO:0052667//phosphomethylethanolamine N-methyltransferase activity;GO:0044822//poly(A) RNA binding;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity;GO:0043782//cobalt-precorrin-3 C17-methyltransferase activity;GO:0043770//demethylmenaquinone methyltransferase activity;GO:0016205//selenocysteine methyltransferase activity;GO:0008988//rRNA (adenine-N6-)-methyltransferase activity;GO:0043777//cobalt-precorrin-7 C15-methyltransferase activity;GO:0019702//protein-arginine N5-methyltransferase activity;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0070677//rRNA (cytosine-2'-O-)-methyltransferase activity;GO:0008650//rRNA (uridine-2'-O-)-methyltransferase activity;GO:0080012//trihydroxyferuloyl spermidine O-methyltransferase activity;GO:0034807//4,5-dihydroxybenzo(a)pyrene methyltransferase activity;GO:0043780//cobalt-precorrin-5B C1-methyltransferase activity;GO:0043776//cobalt-precorrin-6B C5-methyltransferase activity;GO:0052624//2-phytyl-1,4-naphthoquinone methyltransferase activity;GO:0034931//1-hydroxypyrene methyltransferase activity;GO:0018423//protein C-terminal leucine carboxyl O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0043834//trimethylamine methyltransferase activity;GO:0008174//mRNA methyltransferase activity;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0034933//1-hydroxy-6-methoxypyrene methyltransferase activity;GO:0051994//P-methyltransferase activity;GO:0043791//dimethylamine methyltransferase activity;GO:0043851//methanol-specific methylcobalamin:coenzyme M methyltransferase activity;GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0052666//tRNA (cytosine-2'-O-)-methyltransferase activity;GO:0043827//tRNA (adenine-57, 58-N(1)-) methyltransferase activity;GO:0043833//methylamine-specific methylcobalamin:coenzyme M methyltransferase activity;GO:0003676//nucleic acid binding;GO:0008172//S-methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0043852//monomethylamine methyltransferase activity;GO:0018707//1-phenanthrol methyltransferase activity;GO:0030792//methylarsonite methyltransferase activity;GO:0009383//rRNA (cytosine-C5-)-methyltransferase activity;GO:0071424//rRNA (cytosine-N4-)-methyltransferase activity","GO:0010467//gene expression;GO:0001510//RNA methylation;GO:0006730//one-carbon metabolic process;GO:0009451//RNA modification;GO:0006364//rRNA processing","K20095//16S rRNA (guanosine(1370)-2'-O)-methyltransferase [EC:2.1.1.-]","gi|157818915|ref|NP_001101752.1|//RNA methyltransferase-like protein 1 [Rattus norvegicus] "]
[null,360577,2508,107.734374810006,237.28852034403,-1.13916366275651,"DOWN",0.00411456667516634,"Nxn","GO:0005634//nucleus;GO:0005829//cytosol","GO:0047134//protein-disulfide reductase activity;GO:0005515//protein binding;GO:0004791//thioredoxin-disulfide reductase activity","GO:0031397//negative regulation of protein ubiquitination;GO:0030154//cell differentiation;GO:0072358//cardiovascular system development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0098869//cellular oxidant detoxification;GO:0055114//oxidation-reduction process;GO:0045454//cell redox homeostasis","K17609//nucleoredoxin [EC:1.8.1.8]","gi|157818993|ref|NP_001101755.1|//nucleoredoxin [Rattus norvegicus] ;gi|564373232|ref|XP_006246969.1|//PREDICTED: nucleoredoxin isoform X1 [Rattus norvegicus]"]
[null,360638,5144,240.110375754433,91.6305044266146,1.38979788076132,"UP",0.00386708560738098,"Adam11","GO:0031224//intrinsic component of membrane","GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding","GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway","K16067//disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-]","gi|564374354|ref|XP_006247441.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 11 isoform X1 [Rattus norvegicus];gi|817347962|ref|XP_012299439.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 11 isoform X1 [Aotus nancymaae];gi|826342313|ref|XP_012516950.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 11 isoform X1 [Propithecus coquereli]"]
[null,360655,731,90.3426069397615,189.255674331159,-1.06685810614463,"DOWN",0.00409943201848573,"Cd300le","GO:0016020//membrane","NA","NA","K20395//CO300B/D/F antigen","gi|320498033|ref|NP_001189392.1|//Cd300 molecule-like family member E precursor [Rattus norvegicus]"]
[null,360959,2440,6.79953474218995,29.1919421714171,-2.10206225957146,"DOWN",0.000811875823453248,"Htra3","NA","GO:0004175//endopeptidase activity;GO:0019838//growth factor binding","GO:0019538//protein metabolic process;GO:0016049//cell growth","K08785//HtrA serine peptidase 3 [EC:3.4.21.-]","gi|402478640|ref|NP_001257956.1|//serine protease HTRA3 precursor [Rattus norvegicus]"]
[null,361232,1535,189.48611197035,85.8481212241178,1.14223364616364,"UP",0.00846229438972293,"Pak1ip1","GO:0031981//nuclear lumen;GO:0016020//membrane","NA","GO:0007165//signal transduction","K14830//protein MAK11","gi|82654216|ref|NP_001032433.1|//p21-activated protein kinase-interacting protein 1 [Rattus norvegicus]"]
[null,361251,3911,19.0634814116665,47.1759393194959,-1.30723963238858,"DOWN",0.0086210637792771,"Elmo1","GO:0016020//membrane;GO:0043232//intracellular non-membrane-bounded organelle;GO:0044444//cytoplasmic part","GO:0019904//protein domain specific binding","GO:0050688//regulation of defense response to virus;GO:0012501//programmed cell death;GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0006909//phagocytosis","K12366//engulfment and cell motility protein 1","gi|148700731|gb|EDL32678.1|//engulfment and cell motility 1, ced-12 homolog (C. elegans), isoform CRA_b [Mus musculus]"]
[null,361289,2913,9.00000263467283,26.992657638781,-1.58456969954469,"DOWN",0.0141205233620329,"Colec12","GO:0031224//intrinsic component of membrane","GO:0043169//cation binding;GO:0071813//lipoprotein particle binding;GO:0048029//monosaccharide binding;GO:0004888//transmembrane signaling receptor activity","GO:0002758//innate immune response-activating signal transduction;GO:0006909//phagocytosis;GO:0051259//protein oligomerization","K10062//collectin sub-family member 12","gi|71043880|ref|NP_001020892.1|//collectin-12 [Rattus norvegicus]"]
[null,361413,1053,474.146753625522,183.90044849237,1.36640866002702,"UP",0.000669332757355242,"Nudt7","GO:0042579//microbody","GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0016289//CoA hydrolase activity;GO:0046914//transition metal ion binding","GO:0009109//coenzyme catabolic process;GO:0045444//fat cell differentiation;GO:0006084//acetyl-CoA metabolic process;GO:0009117//nucleotide metabolic process","K17879//peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-]","gi|149038257|gb|EDL92617.1|//nudix (nucleoside diphosphate linked moiety X)-type motif 7 (predicted), isoform CRA_d [Rattus norvegicus];gi|672085146|ref|XP_006255739.2|//PREDICTED: LOW QUALITY PROTEIN: peroxisomal coenzyme A diphosphatase NUDT7 [Rattus norvegicus]"]
[null,361431,2684,7.46229434430653,20.1595708447791,-1.43377375483993,"DOWN",0.0257379863652186,"Cbfa2t3","GO:0043231//intracellular membrane-bounded organelle","GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0006351//transcription, DNA-templated;GO:0002573//myeloid leukocyte differentiation","K10053//runt-related transcription factor 1; translocated to, 1","gi|158631260|ref|NP_001101923.1|//protein CBFA2T3 [Rattus norvegicus] "]
[null,361493,2094,66.623353316841,206.985634056917,-1.63543076488341,"DOWN",{"v":2.3873906973559e-06,"d":"2.39E-06"},"Lilrb3l","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0002250//adaptive immune response","K06512//leukocyte immunoglobulin-like receptor","gi|82654234|ref|NP_001032434.1|//leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like precursor [Rattus norvegicus]"]
[null,361512,2057,24.2832218586522,67.1548929883904,-1.46753267128304,"DOWN",0.00267636497347945,"Ehd2","GO:0010008//endosome membrane","GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity","GO:0016197//endosomal transport;GO:0030036//actin cytoskeleton organization;GO:0007599//hemostasis;GO:0009207//purine ribonucleoside triphosphate catabolic process","K12469//EH domain-containing protein 2","gi|67846074|ref|NP_001020068.1|//EH domain-containing protein 2 [Rattus norvegicus]"]
[null,361598,7573,330.087943248212,684.191523850698,-1.05154978747873,"DOWN",0.000506685178220386,"Iqgap1","GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0030054//cell junction","GO:0017048//Rho GTPase binding;GO:0019902//phosphatase binding;GO:0008047//enzyme activator activity","NA","K16848//Ras GTPase-activating-like protein IQGAP1","gi|210032529|ref|NP_001101959.2|//ras GTPase-activating-like protein IQGAP1 [Rattus norvegicus] ;gi|37359752|dbj|BAC97854.1|//mKIAA0051 protein [Mus musculus]"]
[null,361600,3001,22.9346359360176,56.8347554829424,-1.30924542746571,"DOWN",0.00640724284289624,"Tm6sf1","GO:0031224//intrinsic component of membrane;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane","NA","NA","K06853//hyaluronan and proteoglycan link protein 4","gi|564329093|ref|XP_006229503.1|//PREDICTED: transmembrane 6 superfamily member 1 isoform X1 [Rattus norvegicus];gi|157817089|ref|NP_001101960.1|//transmembrane 6 superfamily member 1 [Rattus norvegicus] "]
[null,361621,2953,28.0335743441131,57.6614897045503,-1.04045240686229,"DOWN",0.0223559769395883,"Olfml1","NA","NA","NA","K04593//latrophilin 2;K19909//synaptotagmin-9","gi|61557242|ref|NP_001013210.1|//olfactomedin-like protein 1 precursor [Rattus norvegicus]"]
[null,361689,2394,341.802723220951,705.782249943987,-1.04605925620174,"DOWN",0.0016466298844597,"Unc93b1","GO:0045335//phagocytic vesicle;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0032009//early phagosome;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0000323//lytic vacuole","GO:0035325//Toll-like receptor binding;GO:0008565//protein transporter activity;GO:0005102//receptor binding","GO:0000902//cell morphogenesis;GO:0002224//toll-like receptor signaling pathway;GO:2001184//positive regulation of interleukin-12 secretion;GO:0006886//intracellular protein transport;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002478//antigen processing and presentation of exogenous peptide antigen;GO:0015031//protein transport;GO:2000778//positive regulation of interleukin-6 secretion;GO:0034138//toll-like receptor 3 signaling pathway","K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-]","gi|157817875|ref|NP_001101983.1|//protein unc-93 homolog B1 [Rattus norvegicus];gi|564332335|ref|XP_006230895.1|//PREDICTED: protein unc-93 homolog B1 isoform X1 [Rattus norvegicus]"]
[null,361749,2658,522.536087461922,1046.79793809209,-1.00238040642574,"DOWN",0.0347886469827102,"Il33","GO:0043231//intracellular membrane-bounded organelle;GO:0044421//extracellular region part","GO:0005102//receptor binding","GO:0002696//positive regulation of leukocyte activation;GO:0050709//negative regulation of protein secretion;GO:0031349//positive regulation of defense response;GO:0002823//negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0050714//positive regulation of protein secretion;GO:0002828//regulation of type 2 immune response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0032722//positive regulation of chemokine production","K12967//interleukin 33","gi|62079057|ref|NP_001014188.1|//interleukin-33 [Rattus norvegicus];gi|672040124|ref|XP_008758566.1|//PREDICTED: interleukin-33 isoform X1 [Rattus norvegicus]"]
[null,361775,1722,163.598684692198,72.1828400144559,1.1804333373707,"UP",0.00101057024328677,"Trub1","NA","GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding","GO:0010467//gene expression;GO:0006399//tRNA metabolic process","K03177//tRNA pseudouridine55 synthase [EC:5.4.99.25]","gi|58865918|ref|NP_001012173.1|//probable tRNA pseudouridine synthase 1 [Rattus norvegicus]"]
[null,361790,2677,132.001174471699,277.446823306107,-1.07166051867668,"DOWN",0.00138740590900468,"Ppp1r18","GO:0044424//intracellular part","GO:0019902//phosphatase binding","NA","K17559//phostensin","gi|564396686|ref|XP_006256014.1|//PREDICTED: phostensin isoform X1 [Rattus norvegicus];gi|261399902|ref|NP_001119759.2|//phostensin [Rattus norvegicus];gi|958812891|ref|XP_014687749.1|//PREDICTED: phostensin [Equus asinus]"]
[null,361795,1137,71.7115007934856,147.088097357736,-1.03640408970103,"DOWN",0.0499429969759175,"Ltb","GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005164//tumor necrosis factor receptor binding;GO:0043120//tumor necrosis factor binding;GO:0019955//cytokine binding;GO:0005125//cytokine activity;GO:0032813//tumor necrosis factor receptor superfamily binding","GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0043588//skin development;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0048535//lymph node development;GO:0008544//epidermis development;GO:0010467//gene expression;GO:0006955//immune response;GO:0048534//hematopoietic or lymphoid organ development","K03157//lymphotoxin beta (TNF superfamily, member 3)","gi|47059114|ref|NP_997672.1|//lymphotoxin-beta [Rattus norvegicus]"]
[null,361824,640,6548.60085455983,3199.86609758119,1.03317516466793,"UP",0.00851280979383924,"Chchd10","NA","NA","NA","K11837//ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12];K00558//DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]","gi|55741551|ref|NP_001007009.1|//coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial [Rattus norvegicus]"]
[null,361969,1797,96780.8082411617,241319.633903188,-1.31815240612997,"DOWN",0.000776434844521381,"Fga","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005577//fibrinogen complex;GO:0072562//blood microparticle;GO:0005938//cell cortex;GO:0009897//external side of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0030141//secretory granule;GO:0009986//cell surface;GO:0031091//platelet alpha granule","GO:0050839//cell adhesion molecule binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030674//protein binding, bridging;GO:0005102//receptor binding;GO:0005198//structural molecule activity","GO:0097421//liver regeneration;GO:0072377//blood coagulation, common pathway;GO:0071354//cellular response to interleukin-6;GO:0032355//response to estradiol;GO:0046898//response to cycloheximide;GO:0043152//induction of bacterial agglutination;GO:0007599//hemostasis;GO:0045087//innate immune response;GO:0090277//positive regulation of peptide hormone secretion;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:0044468//envenomation resulting in modulation of blood coagulation in other organism;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0031639//plasminogen activation;GO:0002250//adaptive immune response;GO:0007160//cell-matrix adhesion;GO:0051592//response to calcium ion;GO:0097066//response to thyroid hormone;GO:0033595//response to genistein;GO:0043623//cellular protein complex assembly;GO:1990643//cellular response to granulocyte colony-stimulating factor;GO:0009888//tissue development;GO:0043278//response to morphine;GO:0045921//positive regulation of exocytosis;GO:0009636//response to toxic substance;GO:0045907//positive regulation of vasoconstriction;GO:0071407//cellular response to organic cyclic compound;GO:0023052//signaling;GO:0060416//response to growth hormone;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0010038//response to metal ion;GO:0014911//positive regulation of smooth muscle cell migration;GO:0010165//response to X-ray;GO:0032868//response to insulin;GO:0006953//acute-phase response;GO:0050714//positive regulation of protein secretion;GO:0051258//protein polymerization;GO:0001775//cell activation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation","K03903//fibrinogen alpha chain","gi|144922622|ref|NP_434684.1|//fibrinogen alpha chain isoform 2 precursor [Rattus norvegicus];gi|148683476|gb|EDL15423.1|//fibrinogen, alpha polypeptide, isoform CRA_a [Mus musculus];gi|564336914|ref|XP_006232594.1|//PREDICTED: fibrinogen alpha chain isoform X2 [Rattus norvegicus];gi|511905180|ref|XP_004772068.1|//PREDICTED: fibrinogen alpha chain [Mustela putorius furo];gi|958666375|ref|XP_014699373.1|//PREDICTED: fibrinogen alpha chain [Equus asinus];gi|56797757|ref|NP_001008724.1|//fibrinogen alpha chain isoform 1 precursor [Rattus norvegicus];gi|531999345|ref|XP_005344207.1|//PREDICTED: fibrinogen alpha chain [Microtus ochrogaster]"]
[null,362065,2655,56.0397636501006,125.932072736929,-1.16812298324134,"DOWN",0.00185590235058981,"Wls","GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane","GO:0005515//protein binding","GO:0030177//positive regulation of Wnt signaling pathway;GO:0009798//axis specification;GO:0001704//formation of primary germ layer","NA","gi|148679892|gb|EDL11839.1|//G protein-coupled receptor 177, isoform CRA_a, partial [Mus musculus]"]
[null,362103,1278,482.67380875595,238.510831219012,1.01699376102419,"UP",0.00973370256671404,"Ntmt1","GO:0043231//intracellular membrane-bounded organelle","GO:0008168//methyltransferase activity","GO:0000226//microtubule cytoskeleton organization;GO:0035568//N-terminal peptidyl-proline methylation;GO:0035570//N-terminal peptidyl-serine methylation;GO:0018011//N-terminal peptidyl-alanine methylation","K16219//protein N-terminal methyltransferase [EC:2.1.1.244]","gi|564340256|ref|XP_006233981.1|//PREDICTED: N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X2 [Rattus norvegicus]"]
[null,362211,1804,1.7949797138633,4.69679928397899,-1.38771040247849,"DOWN",0.0381113409484736,"Mall","GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0030135//coated vesicle","NA","NA","NA","gi|62079089|ref|NP_001014204.1|//MAL-like protein [Rattus norvegicus]"]
[null,362214,1966,826.252041929949,399.766341906761,1.0474249216493,"UP",0.00453538846021107,"Nop56","GO:0016020//membrane;GO:0032040//small-subunit processome;GO:0005913//cell-cell adherens junction;GO:0030529//intracellular ribonucleoprotein complex;GO:0031428//box C/D snoRNP complex;GO:0005737//cytoplasm;GO:0070761//pre-snoRNP complex","GO:0030515//snoRNA binding;GO:0003723//RNA binding;GO:1990226//histone methyltransferase binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0044822//poly(A) RNA binding","GO:0000154//rRNA modification;GO:0022613//ribonucleoprotein complex biogenesis","K14564//nucleolar protein 56","gi|71143106|ref|NP_001020903.1|//nucleolar protein 56 [Rattus norvegicus];gi|676263967|gb|KFO20546.1|//Transmembrane channel-like protein 2 [Fukomys damarensis]"]
[null,362263,9884,39.1595093844654,157.215440717816,-2.00530832188796,"DOWN",0.000407303528406004,"Ptprt","GO:0031224//intrinsic component of membrane","GO:0050839//cell adhesion molecule binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity;GO:0042805//actinin binding","GO:0016337//single organismal cell-cell adhesion;GO:0006470//protein dephosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway","K13297//receptor-type tyrosine-protein phosphatase T [EC:3.1.3.48]","gi|157824032|ref|NP_001102073.1|//receptor-type tyrosine-protein phosphatase T [Rattus norvegicus] ;gi|690430259|ref|XP_009316932.1|//PREDICTED: receptor-type tyrosine-protein phosphatase T [Pygoscelis adeliae]"]
[null,362332,9049,6.09062245161713,18.1421613284761,-1.57468475671986,"DOWN",0.0236194458808769,"Flnc","GO:0016020//membrane;GO:0030016//myofibril","GO:0008092//cytoskeletal protein binding","GO:0034330//cell junction organization","K04437//filamin","gi|300797978|ref|NP_001178791.1|//filamin-C [Rattus norvegicus]"]
[null,362374,2883,31.1394861240053,65.7941362517741,-1.07921387617986,"DOWN",0.0210332177216084,"Vopp1","GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0060089//molecular transducer activity","GO:0023052//signaling;GO:0006351//transcription, DNA-templated","NA","gi|157820805|ref|NP_001102100.1|//vesicular, overexpressed in cancer, prosurvival protein 1 precursor [Rattus norvegicus]"]
[null,362430,1230,53.685949177452,137.535388802594,-1.35718642484475,"DOWN",0.00136714503674667,"Clec4a1","NA","GO:0030246//carbohydrate binding;GO:0004871//signal transducer activity","GO:0023052//signaling","K10057//C-type lectin domain family 4 member A","gi|54312106|ref|NP_001005890.1|//C-type lectin domain family 4, member A1 [Rattus norvegicus]"]
[null,362431,779,21.3546674656151,47.8164392369255,-1.16295526784491,"DOWN",0.0492185692429231,"Clec4a3","NA","GO:0030246//carbohydrate binding","NA","K10057//C-type lectin domain family 4 member A","gi|54312112|ref|NP_001005891.1|//C-type lectin domain family 4, member A3 [Rattus norvegicus]"]
[null,362456,1151,135.440103767281,295.321432075693,-1.12463107591252,"DOWN",0.000211057696487583,"Arhgdib","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0044424//intracellular part;GO:0005829//cytosol","GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0048365//Rac GTPase binding;GO:0005092//GDP-dissociation inhibitor activity;GO:0005488//binding;GO:0008047//enzyme activator activity;GO:0003924//GTPase activity","GO:0043087//regulation of GTPase activity;GO:1901164//negative regulation of trophoblast cell migration;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0071461//cellular response to redox state;GO:2000249//regulation of actin cytoskeleton reorganization","K12462//Rho GDP-dissociation inhibitor","gi|57527565|ref|NP_001009600.1|//rho GDP-dissociation inhibitor 2 [Rattus norvegicus]"]
[null,362625,4156,160.073844880587,549.157742908971,-1.7784830166675,"DOWN",{"v":1.14781896354493e-05,"d":"1.15E-05"},"Man1c1","GO:0031228//intrinsic component of Golgi membrane","GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity","GO:0006487//protein N-linked glycosylation;GO:0006029//proteoglycan metabolic process;GO:0019318//hexose metabolic process","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","gi|157822577|ref|NP_001102157.1|//mannosyl-oligosaccharide 1,2-alpha-mannosidase IC [Rattus norvegicus] ;gi|524959392|ref|XP_005079647.1|//PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IC [Mesocricetus auratus]"]
[null,362688,1168,39.975410583111,198.583383489363,-2.31256015341585,"DOWN",{"v":1.21724794465792e-05,"d":"1.22E-05"},"Gemin6","GO:0030529//intracellular ribonucleoprotein complex;GO:0044451//nucleoplasm part;GO:0044444//cytoplasmic part","GO:0005488//binding","GO:0000398//mRNA splicing, via spliceosome","K13134//gem associated protein 6","gi|149050595|gb|EDM02768.1|//gem (nuclear organelle) associated protein 6, isoform CRA_a [Rattus norvegicus];gi|57164099|ref|NP_001009466.1|//gem-associated protein 6 [Rattus norvegicus] "]
[null,362863,3960,6.08466286895562,15.152723355922,-1.31632787317752,"DOWN",0.0428129452902639,"LOC362863","GO:0044424//intracellular part","NA","NA","K19360//nephrocystin-3;K11127//telomerase protein component 1","gi|282158061|ref|NP_001164076.1|//tetratricopeptide repeat protein 41 [Rattus norvegicus]"]
[null,362993,1639,127.324717275454,260.390754037054,-1.03216570841836,"DOWN",0.00759781962521071,"Rnd1","GO:0043232//intracellular non-membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0070161//anchoring junction","GO:0005515//protein binding;GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity","GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0042551//neuron maturation;GO:0006935//chemotaxis;GO:0035556//intracellular signal transduction;GO:0009207//purine ribonucleoside triphosphate catabolic process","K07531//Rho family GTPase 1","gi|61557333|ref|NP_001013240.1|//rho-related GTP-binding protein Rho6 [Rattus norvegicus]"]
[null,363143,3361,52.4040447808042,128.612432148352,-1.29528003069805,"DOWN",0.00610376059901165,"Gnat1","GO:0044297//cell body;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0001750//photoreceptor outer segment","GO:0060089//molecular transducer activity;GO:0032561//guanyl ribonucleotide binding;GO:0019900//kinase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005102//receptor binding;GO:0032403//protein complex binding","GO:0001754//eye photoreceptor cell differentiation;GO:0051342//regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051602//response to electrical stimulus;GO:0007603//phototransduction, visible light;GO:0050953//sensory perception of light stimulus;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0009207//purine ribonucleoside triphosphate catabolic process;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04631//guanine nucleotide-binding protein G(t) subunit alpha 1/2","gi|742171392|ref|XP_010850131.1|//PREDICTED: guanine nucleotide-binding protein G(t) subunit alpha-1 isoform X1 [Bison bison bison];gi|826264285|ref|XP_012494811.1|//PREDICTED: guanine nucleotide-binding protein G(t) subunit alpha-1 [Propithecus coquereli]"]
[null,363195,3264,786.603936948033,369.868667168247,1.08862431694049,"UP",0.000482086061532302,"Gtpbp2","NA","GO:0032561//guanyl ribonucleotide binding;GO:0017111//nucleoside-triphosphatase activity","GO:0009207//purine ribonucleoside triphosphate catabolic process","K14416//elongation factor 1 alpha-like protein","gi|926721323|ref|XP_013829250.1|//PREDICTED: GTP-binding protein 2 [Capra hircus];gi|148691529|gb|EDL23476.1|//GTP binding protein 2, isoform CRA_b, partial [Mus musculus]"]
[null,363447,1642,658.903159210104,1319.08711645368,-1.00140149851499,"DOWN",0.000107986184959095,"Tspan7","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0007166//cell surface receptor signaling pathway","K06571//tetraspanin-7","gi|157818589|ref|NP_001102285.1|//tetraspanin-7 [Rattus norvegicus];gi|159895651|gb|ABX10436.1|//neuroprotective protein 5 [Rattus norvegicus]"]
[null,363930,2602,76.4879698646281,162.281147857356,-1.08519065059819,"DOWN",0.01687594350845,"Selplg","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0001931//uropod;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0005515//protein binding","GO:0007159//leukocyte cell-cell adhesion;GO:0071354//cellular response to interleukin-6;GO:0070741//response to interleukin-6;GO:0050902//leukocyte adhesive activation;GO:0050901//leukocyte tethering or rolling","K06544//selectin P ligand","gi|61557366|ref|NP_001013248.1|//P-selectin glycoprotein ligand 1 precursor [Rattus norvegicus];gi|157100915|emb|CAO91829.1|//P-selectin glycoprotein ligand 1 propeptide precursor [Rattus norvegicus]"]
[null,364396,1476,59.7196298214106,121.575115212401,-1.02557083085645,"DOWN",0.0135518334752623,"Arl11","GO:0044464//cell part;GO:0005622//intracellular","GO:0032561//guanyl ribonucleotide binding;GO:0005525//GTP binding","GO:0002244//hematopoietic progenitor cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0035556//intracellular signal transduction","K07959//ADP-ribosylation factor-like protein 11","gi|61740633|ref|NP_001013451.1|//ADP-ribosylation factor-like protein 11 [Rattus norvegicus]"]
[null,364786,5896,20.5410139826855,65.8228044195139,-1.68008009431123,"DOWN",0.00228327906110583,"Itga8","GO:0005887//integral component of plasma membrane;GO:0044430//cytoskeletal part;GO:0032589//neuron projection membrane;GO:0043025//neuronal cell body","GO:0004871//signal transducer activity","GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042471//ear morphogenesis;GO:0001822//kidney development;GO:0031589//cell-substrate adhesion;GO:0007611//learning or memory;GO:0043062//extracellular structure organization;GO:0007417//central nervous system development;GO:0048869//cellular developmental process","K06584//integrin alpha 8","gi|291190715|ref|NP_001167443.1|//integrin alpha-8 [Rattus norvegicus]"]
[null,365395,1877,207.379981136793,94.6939478790469,1.13093250662815,"UP",0.00215942597681699,"Clcf1","GO:0070062//extracellular exosome;GO:0044421//extracellular region part;GO:0005622//intracellular;GO:0097059//CNTFR-CLCF1 complex;GO:0097058//CRLF-CLCF1 complex","GO:0005125//cytokine activity;GO:0046982//protein heterodimerization activity;GO:0005102//receptor binding;GO:0005127//ciliary neurotrophic factor receptor binding","GO:0030098//lymphocyte differentiation;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0051896//regulation of protein kinase B signaling;GO:0007166//cell surface receptor signaling pathway;GO:2000672//negative regulation of motor neuron apoptotic process;GO:0030890//positive regulation of B cell proliferation;GO:0050727//regulation of inflammatory response;GO:0051466//positive regulation of corticotropin-releasing hormone secretion;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0002830//positive regulation of type 2 immune response;GO:0048711//positive regulation of astrocyte differentiation;GO:0030183//B cell differentiation","K05421//B-cell stimulating factor 3","gi|76563944|ref|NP_997498.2|//cardiotrophin-like cytokine factor 1 [Rattus norvegicus];gi|913495780|ref|XP_005351718.2|//PREDICTED: cardiotrophin-like cytokine factor 1 isoform X1 [Microtus ochrogaster]"]
[null,365583,4130,117.300316167683,241.058898643241,-1.03917878556155,"DOWN",0.00784771071849797,"Dse","GO:0043231//intracellular membrane-bounded organelle","GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives","GO:0030205//dermatan sulfate metabolic process","K01794//chondroitin-glucuronate 5-epimerase [EC:5.1.3.19]","gi|74142284|dbj|BAE31905.1|//unnamed protein product [Mus musculus]"]
[null,365963,1801,35.0571859778833,16.5981049984937,1.07869165752189,"UP",0.0490869665433846,"Lhx8","GO:0043231//intracellular membrane-bounded organelle","GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0008406//gonad development;GO:0007610//behavior;GO:0021879//forebrain neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0042476//odontogenesis","K09375//LIM homeobox protein 6/8","gi|149026292|gb|EDL82535.1|//rCG29002 [Rattus norvegicus]"]
[null,366474,5212,12.6895029435058,50.9488634000448,-2.00541440324684,"DOWN",0.000485109514364337,"Col16a1","GO:0005576//extracellular region","NA","GO:0009987//cellular process","K16630//collagen, type XXII, alpha","gi|149024084|gb|EDL80581.1|//procollagen, type XVI, alpha 1 [Rattus norvegicus]"]
[null,366602,1943,109.925186651939,236.794273192125,-1.10711220794932,"DOWN",0.00900416775188821,"Tspan13","GO:0031224//intrinsic component of membrane","NA","NA","K17356//tetraspanin-13/31","gi|148704909|gb|EDL36856.1|//tetraspanin 13, isoform CRA_b, partial [Mus musculus]"]
[null,366734,2040,23.5611297269751,7.60506741775694,1.63137577387689,"UP",0.0165438528223413,"Bag5","GO:0044444//cytoplasmic part","GO:0019899//enzyme binding","GO:0031397//negative regulation of protein ubiquitination;GO:0044087//regulation of cellular component biogenesis;GO:0012501//programmed cell death","K09559//BCL2-associated athanogene 5","gi|56606102|ref|NP_001008526.1|//BAG family molecular chaperone regulator 5 [Rattus norvegicus]"]
[null,366792,1317,3392.00847820008,1138.51566869958,1.57498562932199,"UP",0.000458132441799861,"Mettl7b","GO:0031090//organelle membrane;GO:0044444//cytoplasmic part","GO:0016741//transferase activity, transferring one-carbon groups","GO:0006730//one-carbon metabolic process","NA","gi|66730429|ref|NP_001019447.1|//methyltransferase-like protein 7B precursor [Rattus norvegicus]"]
[null,367215,893,33.9775748266694,14.9483455137548,1.18459706737481,"UP",0.042978067884767,"Trem3","NA","GO:0005488//binding","GO:0023052//signaling","K14362//triggering receptor expressed on myeloid cells 1","gi|300797456|ref|NP_001178510.1|//triggering receptor expressed on myeloid cells 3 precursor [Rattus norvegicus] "]
[null,367252,7181,28.9047927579255,65.5131185856507,-1.18047509755914,"DOWN",0.0092033658457763,"Mgat4a","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0043169//cation binding","GO:0044238//primary metabolic process","K00738//alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]","gi|58866022|ref|NP_001012225.1|//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 2 [Rattus norvegicus];gi|237512962|ref|NP_001153627.1|//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 1 [Rattus norvegicus]"]
[null,367391,1979,1105.85302900158,3068.68179504894,-1.47245939418447,"DOWN",0.00133932099466905,"Marco","GO:0016020//membrane","GO:0004872//receptor activity","GO:0007165//signal transduction","K13884//macrophage receptor with collagenous structure","gi|157823909|ref|NP_001102481.1|//macrophage receptor MARCO [Rattus norvegicus]"]
[null,367901,1451,19.9531004721125,46.2387744519741,-1.21249021870222,"DOWN",0.0398503141995159,"Btk","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0044425//membrane part;GO:0031982//vesicle;GO:0042629//mast cell granule;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0035091//phosphatidylinositol binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0032559//adenyl ribonucleotide binding","GO:0001812//positive regulation of type I hypersensitivity;GO:0021700//developmental maturation;GO:0034614//cellular response to reactive oxygen species;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0009888//tissue development;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019932//second-messenger-mediated signaling;GO:0071226//cellular response to molecule of fungal origin;GO:0001818//negative regulation of cytokine production;GO:0045087//innate immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0002553//histamine secretion by mast cell;GO:0006468//protein phosphorylation;GO:0001805//positive regulation of type III hypersensitivity;GO:0006915//apoptotic process;GO:0046777//protein autophosphorylation;GO:0006979//response to oxidative stress;GO:0048469//cell maturation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002441//histamine secretion involved in inflammatory response","K07370//Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]","gi|56119141|ref|NP_001007799.1|//tyrosine-protein kinase BTK [Rattus norvegicus];gi|149055439|gb|EDM07023.1|//Bruton agammaglobulinemia tyrosine kinase [Rattus norvegicus]"]
[null,367903,3320,8.50429626491565,20.6713988211393,-1.28137225622242,"DOWN",0.0325477995846698,"Armcx2","GO:0031224//intrinsic component of membrane","NA","NA","NA","gi|62079281|ref|NP_001014296.1|//armadillo repeat-containing X-linked protein 2 [Rattus norvegicus]"]
[null,396551,2231,135.390618411058,67.0576260306305,1.01365445910256,"UP",0.0291342586651775,"Ugt1a3","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane","GO:0008194//UDP-glycosyltransferase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0005501//retinoid binding","GO:0009887//animal organ morphogenesis;GO:0001523//retinoid metabolic process;GO:0009698//phenylpropanoid metabolic process;GO:0051384//response to glucocorticoid;GO:0045471//response to ethanol","K00699//glucuronosyltransferase [EC:2.4.1.17]","gi|66773200|ref|NP_958827.1|//UDP-glucuronosyltransferase 1-3 precursor [Rattus norvegicus]"]
[null,399475,1042,122.433703856204,49.1667523721994,1.31624579279939,"UP",0.0286697377644742,"Adm2","NA","NA","GO:0007610//behavior;GO:0008217//regulation of blood pressure;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","NA","gi|148672410|gb|EDL04357.1|//adrenomedullin 2, isoform CRA_a, partial [Mus musculus]"]
[null,406161,5354,410.542214494317,5431.84286113988,-3.72583926258856,"DOWN",{"v":3.26489076385274e-28,"d":"3.26E-28"},"C4b","GO:0044421//extracellular region part","GO:0061135//endopeptidase regulator activity","GO:0010466//negative regulation of peptidase activity;GO:0006952//defense response;GO:0006939//smooth muscle contraction;GO:0002455//humoral immune response mediated by circulating immunoglobulin","K03989//complement component 4","gi|50657362|ref|NP_001002805.1|//complement component 4, gene 2 precursor [Rattus norvegicus]"]
[null,414790,1098,188.441263853904,500.704971906868,-1.40984586804435,"DOWN",0.00590062421739316,"RT1-CE13","GO:0031224//intrinsic component of membrane;GO:0042611//MHC protein complex","GO:0005488//binding","GO:0048002//antigen processing and presentation of peptide antigen","K06751//major histocompatibility complex, class I","gi|57012416|ref|NP_001008836.1|//RT1 class I, locus CE13 precursor [Rattus norvegicus]"]
[null,445442,5175,223.352045721507,591.643853122597,-1.40540952152286,"DOWN",0.0031561952701119,"Thbs1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005577//fibrinogen complex;GO:0009897//external side of plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0031091//platelet alpha granule","GO:0001968//fibronectin binding;GO:0005102//receptor binding;GO:0071813//lipoprotein particle binding;GO:0005178//integrin binding;GO:0008201//heparin binding;GO:0050431//transforming growth factor beta binding;GO:0001786//phosphatidylserine binding;GO:0070051//fibrinogen binding;GO:0070052//collagen V binding;GO:0030169//low-density lipoprotein particle binding;GO:0043236//laminin binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0017134//fibroblast growth factor binding;GO:0005539//glycosaminoglycan binding;GO:0032403//protein complex binding","GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0009746//response to hexose;GO:0009968//negative regulation of signal transduction;GO:0032026//response to magnesium ion;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0002468//dendritic cell antigen processing and presentation;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0001818//negative regulation of cytokine production;GO:0009749//response to glucose;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010746//regulation of plasma membrane long-chain fatty acid transport;GO:0001937//negative regulation of endothelial cell proliferation;GO:0010466//negative regulation of peptidase activity;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:0043652//engulfment of apoptotic cell;GO:0003151//outflow tract morphogenesis;GO:0032103//positive regulation of response to external stimulus;GO:0010761//fibroblast migration;GO:0006915//apoptotic process;GO:0048545//response to steroid hormone;GO:0070848//response to growth factor;GO:0034612//response to tumor necrosis factor;GO:0002544//chronic inflammatory response;GO:0006412//translation;GO:0030194//positive regulation of blood coagulation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0002040//sprouting angiogenesis;GO:0003197//endocardial cushion development;GO:0006911//phagocytosis, engulfment;GO:0010759//positive regulation of macrophage chemotaxis;GO:0032695//negative regulation of interleukin-12 production;GO:0045727//positive regulation of translation;GO:0033574//response to testosterone;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0010038//response to metal ion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0071732//cellular response to nitric oxide;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0016525//negative regulation of angiogenesis;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006954//inflammatory response;GO:0048266//behavioral response to pain;GO:0006464//cellular protein modification process;GO:0045765//regulation of angiogenesis;GO:0003417//growth plate cartilage development;GO:0010755//regulation of plasminogen activation;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0010763//positive regulation of fibroblast migration;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016310//phosphorylation;GO:0001952//regulation of cell-matrix adhesion;GO:0034976//response to endoplasmic reticulum stress;GO:0071356//cellular response to tumor necrosis factor;GO:0010595//positive regulation of endothelial cell migration;GO:0007263//nitric oxide mediated signal transduction;GO:0001819//positive regulation of cytokine production;GO:0030823//regulation of cGMP metabolic process;GO:0051918//negative regulation of fibrinolysis;GO:0018149//peptide cross-linking;GO:0045766//positive regulation of angiogenesis;GO:0001935//endothelial cell proliferation;GO:0009612//response to mechanical stimulus;GO:0042493//response to drug;GO:0043032//positive regulation of macrophage activation;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051592//response to calcium ion;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001953//negative regulation of cell-matrix adhesion;GO:0051897//positive regulation of protein kinase B signaling;GO:0007050//cell cycle arrest;GO:0032905//transforming growth factor beta1 production;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0012502//induction of programmed cell death;GO:0002696//positive regulation of leukocyte activation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0000187//activation of MAPK activity;GO:0010596//negative regulation of endothelial cell migration;GO:0010757//negative regulation of plasminogen activation;GO:0003416//endochondral bone growth;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0022402//cell cycle process;GO:0071636//positive regulation of transforming growth factor beta production;GO:0006955//immune response;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K16857//thrombospondin 1","gi|61556835|ref|NP_001013080.1|//thrombospondin-1 precursor [Rattus norvegicus]"]
[null,450235,2123,19.6233623464651,71.3043527132371,-1.86141788748737,"DOWN",0.00105968472257,"Adgre4","GO:0031224//intrinsic component of membrane","GO:0046872//metal ion binding;GO:0004872//receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08445//egf-like module containing, mucin-like, hormone receptor-like 4","gi|56090590|ref|NP_001007559.1|//EGF-like module-containing mucin-like hormone receptor-like 4 precursor [Rattus norvegicus]"]
[null,474143,831,4.55800020320499,11.9711306618765,-1.39308652585353,"DOWN",0.0404486580064578,"Clec4a","GO:0031224//intrinsic component of membrane","GO:0030246//carbohydrate binding;GO:0004871//signal transducer activity","GO:0006952//defense response","K10057//C-type lectin domain family 4 member A","gi|148235584|ref|NP_001005899.2|//C-type lectin domain family 4 member A [Rattus norvegicus]"]
[null,494499,806,3848.3206078127,1385.81940774484,1.47348973086842,"UP",0.00161613191071871,"Gsta5","GO:0031965//nuclear membrane;GO:0044444//cytoplasmic part","GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0042277//peptide binding","GO:0032502//developmental process;GO:0006805//xenobiotic metabolic process","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|58331251|ref|NP_001010921.1|//glutathione S-transferase alpha-2 [Rattus norvegicus]"]
[null,494500,1488,2337.95653139904,952.261165625865,1.29581890257163,"UP",0.00203189425060373,"Gsta3","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004364//glutathione transferase activity","GO:0046223//aflatoxin catabolic process;GO:0001657//ureteric bud development","K00799//glutathione S-transferase [EC:2.5.1.18];K06840//semaphorin 3","gi|58331159|ref|NP_001009920.1|//glutathione S-transferase alpha-5 isoform 1 [Rattus norvegicus];gi|167527177|ref|XP_001747921.1|//hypothetical protein [Monosiga brevicollis MX1]"]
[null,497811,5457,1224.94209910119,2648.84339917547,-1.11264899630784,"DOWN",0.00049325344459884,"Xdh","GO:0005615//extracellular space;GO:0042579//microbody;GO:0005777//peroxisome;GO:0016529//sarcoplasmic reticulum","GO:0009055//electron carrier activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0042802//identical protein binding;GO:0004855//xanthine oxidase activity;GO:0005506//iron ion binding;GO:0016726//oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor;GO:0046914//transition metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0004854//xanthine dehydrogenase activity;GO:0051536//iron-sulfur cluster binding;GO:0042803//protein homodimerization activity;GO:0016903//oxidoreductase activity, acting on the aldehyde or oxo group of donors;GO:0043546//molybdopterin cofactor binding;GO:0016727//oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor;GO:0050662//coenzyme binding","GO:0007595//lactation;GO:0007589//body fluid secretion;GO:2001213//negative regulation of vasculogenesis;GO:0010629//negative regulation of gene expression;GO:0006145//purine nucleobase catabolic process;GO:0055114//oxidation-reduction process;GO:0010038//response to metal ion;GO:0051898//negative regulation of protein kinase B signaling;GO:0045602//negative regulation of endothelial cell differentiation;GO:0001937//negative regulation of endothelial cell proliferation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0001894//tissue homeostasis;GO:1900745//positive regulation of p38MAPK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030855//epithelial cell differentiation;GO:0009115//xanthine catabolic process","K00106//xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]","gi|313103571|pdb|3AN1|A//Chain A, Crystal Structure Of Rat D428a Mutant, Urate Bound Form;gi|8394544|ref|NP_058850.1|//xanthine dehydrogenase/oxidase [Rattus norvegicus]"]
[null,497942,1730,113.542087108106,231.858377365934,-1.03001668793129,"DOWN",0.00211354568263846,"Cxcl16","GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part","GO:0005125//cytokine activity;GO:0030169//low-density lipoprotein particle binding;GO:0004888//transmembrane signaling receptor activity","GO:0016477//cell migration;GO:0034097//response to cytokine;GO:0016049//cell growth","K10035//C-X-C motif chemokine 16","gi|62945312|ref|NP_001017478.1|//C-X-C motif chemokine 16 precursor [Rattus norvegicus]"]
[null,498022,995,54.7274836446731,244.009243622261,-2.15659837293198,"DOWN",{"v":1.04986883086901e-08,"d":"1.05E-08"},"RGD1559482","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004871//signal transducer activity;GO:0005488//binding","GO:0050715//positive regulation of cytokine secretion","K06719//CD300 antigen","gi|564375252|ref|XP_006247801.1|//PREDICTED: CMRF35-like molecule isoform X1 [Rattus norvegicus];gi|269973889|ref|NP_001161757.1|//immune activating receptor CD300d1 precursor [Rattus norvegicus]"]
[null,498128,1249,14.4473440642946,34.2370171001566,-1.24475271398166,"DOWN",0.0178379101650425,"Mcemp1","GO:0044464//cell part;GO:0016021//integral component of membrane","NA","NA","K20280//trafficking protein particle complex subunit 5;K13438//resistin;K17513//C-type lectin superfamily 17 member A","gi|197387482|ref|NP_001128074.1|//mast cell-expressed membrane protein 1 [Rattus norvegicus] "]
[null,498282,3672,69.935468381029,161.770765806365,-1.20985469491247,"DOWN",0.00805341389810497,"Arhgap30","NA","NA","NA","K17933//Rho GTPase-activating protein 33","gi|157818617|ref|NP_001102547.1|//rho GTPase-activating protein 30 [Rattus norvegicus] "]
[null,498356,2221,48.2188080698435,148.143058603698,-1.6193231346812,"DOWN",0.00117902395855416,"Shisa3","GO:0043231//intracellular membrane-bounded organelle","NA","GO:0032501//multicellular organismal process","NA","gi|157818893|ref|NP_001102557.1|//protein shisa-3 homolog precursor [Rattus norvegicus]"]
[null,498545,1696,1095.75632941125,2767.11498292305,-1.33645558170074,"DOWN",0.00287711859868542,"Tsc22d1","GO:0043231//intracellular membrane-bounded organelle","GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0006351//transcription, DNA-templated","K10955//intestinal mucin-2;K11661//helicase SRCAP [EC:3.6.4.-];K13908//mucin-5B;K11649//SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C","gi|6678315|ref|NP_033392.1|//TSC22 domain family protein 1 isoform 2 [Mus musculus];gi|158186700|ref|NP_001103382.1|//TSC22 domain family protein 1 isoform 1 [Rattus norvegicus] "]
[null,498547,1582,26.1717335737396,55.1561570292424,-1.07551245211727,"DOWN",0.0370534385112377,"Epsti1","NA","NA","NA","K10433//microtubule-associated protein 7;K18626//trichohyalin","gi|112984176|ref|NP_001037722.1|//epithelial-stromal interaction protein 1 [Rattus norvegicus]"]
[null,498564,2314,4.97063735448938,20.8923180052716,-2.07146981173831,"DOWN",0.00180767515720228,"Itgbl1","GO:0005887//integral component of plasma membrane","GO:0004871//signal transducer activity","GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion","K06493//integrin beta 3;K06588//integrin beta 5","gi|62945368|ref|NP_001017505.1|//integrin beta-like protein 1 precursor [Rattus norvegicus]"]
[null,498638,5645,339.265664168199,764.277798914051,-1.17168169533624,"DOWN",0.0136701932169911,"Msr1","NA","NA","NA","K19721//collagen, type V/XI/XXIV/XXVII, alpha;K06558//macrophage scavenger receptor 1;K13912//deleted in malignant brain tumors 1 protein","gi|564389351|ref|XP_006253268.1|//PREDICTED: macrophage scavenger receptor types I and II isoform X1 [Rattus norvegicus];gi|697003280|ref|XP_009567802.1|//PREDICTED: collagen alpha-1(V) chain isoform X2 [Cuculus canorus];gi|984100558|ref|XP_015341532.1|//PREDICTED: macrophage scavenger receptor types I and II isoform X1 [Marmota marmota marmota];gi|532039468|ref|XP_005362593.1|//PREDICTED: macrophage scavenger receptor types I and II [Microtus ochrogaster]"]
[null,498690,1074,92.669398841915,211.114690916471,-1.18786205764946,"DOWN",0.00453936502937401,"Ctla2a","NA","GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity;GO:0004866//endopeptidase inhibitor activity;GO:0005488//binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","NA","K01365//cathepsin L [EC:3.4.22.15]","gi|157819701|ref|NP_001102585.1|//protein CTLA-2-alpha [Rattus norvegicus] ;gi|564390202|ref|XP_006253587.1|//PREDICTED: protein CTLA-2-alpha isoform X1 [Rattus norvegicus]"]
[null,498750,731,10.2748611775154,4.17497203244237,1.29928046363144,"UP",0.0480702210890958,"LOC498750","GO:0044464//cell part","NA","NA","NA","gi|291395715|ref|XP_002714269.1|//PREDICTED: uncharacterized protein C6orf62 homolog isoform X1 [Oryctolagus cuniculus]"]
[null,498757,1747,10.3577188132101,28.2915395753225,-1.44966438930826,"DOWN",0.0234757903296003,"Aoah","NA","NA","GO:0044255//cellular lipid metabolic process;GO:0031348//negative regulation of defense response","K01065//acyloxyacyl hydrolase [EC:3.1.1.77]","gi|300794357|ref|NP_001178869.1|//acyloxyacyl hydrolase precursor [Rattus norvegicus]"]
[null,498840,2040,16.7043062039385,41.0456818852469,-1.2970103915634,"DOWN",0.0128048630834035,"Tmem173","GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane","GO:0042802//identical protein binding;GO:0019900//kinase binding","GO:0043393//regulation of protein binding;GO:0032606//type I interferon production;GO:0012501//programmed cell death;GO:0043330//response to exogenous dsRNA;GO:0000060//protein import into nucleus, translocation;GO:0050691//regulation of defense response to virus by host;GO:0042307//positive regulation of protein import into nucleus","K12654//transmembrane protein 173","gi|564393107|ref|XP_006254663.1|//PREDICTED: stimulator of interferon genes protein isoform X1 [Rattus norvegicus]"]
[null,498940,2065,655.942161469192,280.088475913948,1.22768598324841,"UP",0.00158067914358662,"Ces2h","GO:0044432//endoplasmic reticulum part","GO:0003824//catalytic activity","GO:0008152//metabolic process;GO:0042221//response to chemical","K03927//carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]","gi|112984146|ref|NP_001037723.1|//carboxylesterase 2 isoform 1 precursor [Rattus norvegicus];gi|298493216|ref|NP_001177275.1|//carboxylesterase 2 isoform 2 precursor [Rattus norvegicus]"]
[null,498951,1978,175.927307486938,484.180588478144,-1.46056580497274,"DOWN",0.0187989958619391,"Il34","GO:0044421//extracellular region part;GO:0005615//extracellular space","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005126//cytokine receptor binding","GO:0001932//regulation of protein phosphorylation;GO:0008283//cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0045657//positive regulation of monocyte differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0006954//inflammatory response","NA","gi|148679522|gb|EDL11469.1|//RIKEN cDNA 2010004A03, isoform CRA_a, partial [Mus musculus]"]
[null,499270,4568,334.879146223278,129.6319971805,1.36921867467891,"UP",0.00960380933692934,"Prss53","GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004252//serine-type endopeptidase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides","GO:0006508//proteolysis;GO:0019538//protein metabolic process","K09630//polyserase 2 [EC:3.4.21.-]","gi|157820951|ref|NP_001102626.1|//serine protease 53 precursor [Rattus norvegicus] ;gi|564331111|ref|XP_006230386.1|//PREDICTED: serine protease 53 isoform X2 [Rattus norvegicus]"]
[null,499537,5552,126.884503917795,268.314930836291,-1.080411450772,"DOWN",0.0330704910877009,"Fyb","GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane","GO:0005515//protein binding;GO:0005102//receptor binding;GO:0032403//protein complex binding","GO:0007165//signal transduction;GO:0072659//protein localization to plasma membrane;GO:0006955//immune response;GO:0045576//mast cell activation;GO:0002274//myeloid leukocyte activation","K17698//FYN binding protein","gi|564335481|ref|XP_006232081.1|//PREDICTED: FYN-binding protein isoform X4 [Rattus norvegicus]"]
[null,499615,2084,77.9549849668798,163.964840279214,-1.07267329777313,"DOWN",0.00554636436694343,"Lhfp","NA","NA","NA","NA","gi|157821755|ref|NP_001102653.1|//lipoma HMGIC fusion partner precursor [Rattus norvegicus]"]
[null,499689,1593,1591.71607336738,783.225511718961,1.02308335102664,"UP",0.0147122475826732,"Gstm4","GO:0044444//cytoplasmic part;GO:0005737//cytoplasm","GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:0042178//xenobiotic catabolic process;GO:0006807//nitrogen compound metabolic process;GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0018916//nitrobenzene metabolic process","K00799//glutathione S-transferase [EC:2.5.1.18]","gi|148669993|gb|EDL01940.1|//mCG144942, isoform CRA_a, partial [Mus musculus]"]
[null,499702,4792,22.6527318266265,73.0830186293925,-1.6898511805648,"DOWN",0.00212486782811411,"Synpo2","NA","NA","NA","K21112//synaptopodin;K19867//LIM domain-binding protein 3;K06086//sorbin and SH3 domain containing 1","gi|300794803|ref|NP_001178892.1|//synaptopodin-2 [Rattus norvegicus]"]
[null,499991,3112,903.094231824126,3159.78699387941,-1.80687887115844,"DOWN",{"v":6.91170630122889e-06,"d":"6.91E-06"},"Steap4","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0050662//coenzyme binding","GO:0000041//transition metal ion transport;GO:0008152//metabolic process;GO:0030154//cell differentiation","K19876//metalloreductase STEAP4 [EC:1.16.1.-]","gi|112984288|ref|NP_001037730.1|//metalloreductase STEAP4 [Rattus norvegicus]"]
[null,500040,2396,45.3359510568609,108.390590056427,-1.25751205917581,"DOWN",0.00346259929593015,"Tes","GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction","GO:0046914//transition metal ion binding","NA","K04511//prickle","gi|86129590|ref|NP_001034433.1|//testin [Rattus norvegicus]"]
[null,500237,2244,152.832248708983,72.9579389946993,1.06681211440255,"UP",0.0392448672405821,"Cml2","GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane","GO:0043849//Ras palmitoyltransferase activity;GO:0016751//S-succinyltransferase activity;GO:0004147//dihydrolipoamide branched chain acyltransferase activity;GO:0016750//O-succinyltransferase activity;GO:0016749//N-succinyltransferase activity;GO:0034738//lanosterol O-acyltransferase activity;GO:0043741//L-2-aminoadipate N-acetyltransferase activity;GO:0046941//azetidine-2-carboxylic acid acetyltransferase activity;GO:0034915//2-methylhexanoyl-CoA C-acetyltransferase activity;GO:0016413//O-acetyltransferase activity;GO:0034945//2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity;GO:0043806//keto acid formate lyase activity;GO:0018030//peptidyl-lysine N6-myristoyltransferase activity;GO:0016753//O-sinapoyltransferase activity;GO:0018712//3-hydroxybutyryl-CoA thiolase activity;GO:0090595//acetyl-CoA:L-lysine N6-acetyltransferase;GO:0016418//S-acetyltransferase activity;GO:0016412//serine O-acyltransferase activity;GO:0016414//O-octanoyltransferase activity;GO:0008951//palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity;GO:0052858//peptidyl-lysine acetyltransferase activity;GO:0018713//3-ketopimelyl-CoA thiolase activity;GO:0016454//C-palmitoyltransferase activity;GO:0016419//S-malonyltransferase activity;GO:0016406//carnitine O-acyltransferase activity;GO:0019186//acyl-CoA N-acyltransferase activity;GO:0018031//peptidyl-lysine N6-palmitoyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016416//O-palmitoyltransferase activity;GO:0016407//acetyltransferase activity;GO:0034919//butyryl-CoA 2-C-propionyltransferase activity;GO:0018711//benzoyl acetate-CoA thiolase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0034848//naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity;GO:0034851//2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity;GO:0032216//glucosaminyl-phosphotidylinositol O-acyltransferase activity;GO:0034737//ergosterol O-acyltransferase activity","GO:0007369//gastrulation;GO:0001702//gastrulation with mouth forming second;GO:0007162//negative regulation of cell adhesion","K20180//vacuolar protein sorting-associated protein 16;K20838//N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-];K18309//aspartate N-acetyltransferase [EC:2.3.1.17]","gi|291045290|ref|NP_001166920.1|//probable N-acetyltransferase CML2 [Rattus norvegicus] "]
[null,500245,1266,26.8325142309708,80.8594479536654,-1.59143411125855,"DOWN",0.00653242234451151,"Bmp10","GO:0044421//extracellular region part;GO:0031674//I band","GO:0005102//receptor binding","GO:0031032//actomyosin structure organization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016049//cell growth;GO:0055008//cardiac muscle tissue morphogenesis;GO:0003300//cardiac muscle hypertrophy;GO:0060343//trabecula formation;GO:0001934//positive regulation of protein phosphorylation;GO:0055013//cardiac muscle cell development;GO:0010594//regulation of endothelial cell migration;GO:0014855//striated muscle cell proliferation;GO:0008284//positive regulation of cell proliferation","K05503//bone morphogenetic protein 9/10","gi|73532772|ref|NP_001026994.1|//bone morphogenetic protein 10 precursor [Rattus norvegicus]"]
[null,500590,1416,29.5228690608888,103.274400116948,-1.80657784431347,"DOWN",{"v":3.12914809117248e-05,"d":"3.13E-05"},"Tnfrsf9","GO:0009986//cell surface;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0044425//membrane part","GO:0019955//cytokine binding;GO:0004871//signal transducer activity;GO:0005488//binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0050794//regulation of cellular process;GO:2001183//negative regulation of interleukin-12 secretion;GO:2001180//negative regulation of interleukin-10 secretion;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0032496//response to lipopolysaccharide;GO:0006954//inflammatory response;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0042981//regulation of apoptotic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0070207//protein homotrimerization;GO:0008285//negative regulation of cell proliferation","K05146//tumor necrosis factor receptor superfamily member 9","gi|71043922|ref|NP_001020944.1|//tumor necrosis factor receptor superfamily member 9 precursor [Rattus norvegicus]"]
[null,500690,3638,129.567005409117,64.487464912692,1.00660771724269,"UP",0.0186929773755039,"Map3k9","NA","NA","NA","K04417//mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]","gi|403224991|ref|NP_001094342.1|//mitogen-activated protein kinase kinase kinase 9 [Rattus norvegicus]"]
[null,500824,4732,31.2404843003249,68.6619742027091,-1.13609452017674,"DOWN",0.0384131011307867,"Fgd6","GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0043232//intracellular non-membrane-bounded organelle","GO:0043169//cation binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0051020//GTPase binding","GO:0030035//microspike assembly;GO:0065008//regulation of biological quality;GO:0007010//cytoskeleton organization","K05724//FYVE, RhoGEF and PH domain containing 5/6","gi|212549635|ref|NP_001131117.1|//FYVE, RhoGEF and PH domain-containing protein 6 [Rattus norvegicus] "]
[null,500904,1496,81.866015174404,170.342892195166,-1.0571051711209,"DOWN",0.0152045006090897,"Ncf4","GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part","GO:0005543//phospholipid binding","GO:0009987//cellular process","K08012//neutrophil cytosolic factor 4","gi|187937026|ref|NP_001120776.1|//neutrophil cytosol factor 4 [Rattus norvegicus]"]
[null,500917,768,47.8460919929022,17.8318873811427,1.4239416817815,"UP",0.0287892302254609,"Odf3b","NA","NA","NA","NA","gi|300795403|ref|NP_001178921.1|//outer dense fiber protein 3B [Rattus norvegicus];gi|564361549|ref|XP_006242299.1|//PREDICTED: outer dense fiber protein 3B isoform X1 [Rattus norvegicus]"]
[null,501065,1519,53.486302290184,144.276267221722,-1.43159262939348,"DOWN",0.000316296519449576,"Cmtm7","GO:0031224//intrinsic component of membrane;GO:0044421//extracellular region part","GO:0005102//receptor binding","GO:0042221//response to chemical","NA","gi|157817939|ref|NP_001102770.1|//CKLF-like MARVEL transmembrane domain-containing protein 7 [Rattus norvegicus]"]
[null,501072,1570,19360.6841372935,6750.6313412441,1.52003559402247,"UP",0.0206130957247842,"Acaa1b","GO:0016020//membrane;GO:0044439//peroxisomal part;GO:0005739//mitochondrion;GO:0005777//peroxisome","GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0005515//protein binding;GO:0016401//palmitoyl-CoA oxidase activity;GO:0016453//C-acetyltransferase activity","GO:0006635//fatty acid beta-oxidation;GO:0000038//very long-chain fatty acid metabolic process;GO:0031667//response to nutrient levels;GO:0009725//response to hormone;GO:0008206//bile acid metabolic process","K07513//acetyl-CoA acyltransferase 1 [EC:2.3.1.16]","gi|149018281|gb|EDL76922.1|//rCG25918, isoform CRA_a [Rattus norvegicus];gi|90968642|ref|NP_001035108.1|//3-ketoacyl-CoA thiolase B, peroxisomal precursor [Rattus norvegicus];gi|135742|sp|P07871.2|THIKB_RAT//RecName: Full=3-ketoacyl-CoA thiolase B, peroxisomal; AltName: Full=Acetyl-CoA acyltransferase B; AltName: Full=Beta-ketothiolase B; AltName: Full=Peroxisomal 3-oxoacyl-CoA thiolase B; Flags: Precursor"]
[null,501174,2992,1871.96702592676,4017.57461274172,-1.10176979473315,"DOWN",0.00143611653890499,"Pid1","GO:0044424//intracellular part","NA","NA","K14960//COMPASS component SPP1;K06238//collagen, type VI, alpha","gi|160333166|ref|NP_001103963.1|//PTB-containing, cubilin and LRP1-interacting protein [Rattus norvegicus];gi|947204397|ref|XP_014437905.1|//PREDICTED: PTB-containing, cubilin and LRP1-interacting protein [Tupaia chinensis]"]
[null,501736,1514,124.648730069237,276.975288283077,-1.1518890802427,"DOWN",0.00761290678195678,"Cd300a","GO:0031224//intrinsic component of membrane","GO:0019899//enzyme binding","NA","K06719//CD300 antigen","gi|329112553|ref|NP_001192277.1|//CMRF35-like molecule 8 precursor [Rattus norvegicus]"]
[null,502020,3171,50.937272293151,110.169567113441,-1.11293214348593,"DOWN",0.00174623103129058,"Lrch1","NA","NA","NA","K19613//leucine-rich repeat protein SHOC2;K10130//leucine-rich repeats and death domain-containing protein","gi|197927118|ref|NP_001128199.1|//leucine-rich repeat and calponin homology domain-containing protein 1 [Rattus norvegicus]"]
[null,502902,2429,40.3251729930599,110.089773233027,-1.44892782866648,"DOWN",0.0081935450684022,"Clec7a","GO:0009986//cell surface","GO:0001872//(1->3)-beta-D-glucan binding;GO:0004872//receptor activity","GO:0007155//cell adhesion;GO:0002220//innate immune response activating cell surface receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0045807//positive regulation of endocytosis;GO:0001878//response to yeast;GO:0006909//phagocytosis","K10074//C-type lectin domain family 7 member A","gi|197267597|dbj|BAG69161.1|//C-type lectin domain family 7 member A transcript variant 2 [Rattus norvegicus];gi|187469451|gb|AAI66774.1|//Clec7a protein [Rattus norvegicus]"]
[null,503035,3764,20.9551337296837,44.7789320181335,-1.09551639181837,"DOWN",0.0337667623054921,"Tmem229b","GO:0044464//cell part;GO:0016021//integral component of membrane","NA","NA","NA","gi|564356483|ref|XP_006240338.1|//PREDICTED: transmembrane protein 229B isoform X3 [Rattus norvegicus];gi|564356481|ref|XP_006240337.1|//PREDICTED: transmembrane protein 229B isoform X2 [Rattus norvegicus]"]
[null,503049,1888,267.108114178472,85.6915622875079,1.64019874274273,"UP",0.000212450519701879,"Acot5","GO:0042579//microbody","GO:0005488//binding","GO:0006732//coenzyme metabolic process;GO:0006631//fatty acid metabolic process","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","gi|119310193|ref|NP_001073177.1|//acyl-coenzyme A thioesterase 5 [Rattus norvegicus]"]
[null,503568,2982,225.160510024447,82.1489944273045,1.45463900065938,"UP",0.00565337074247215,"Slc13a4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0015382//sodium:sulfate symporter activity;GO:0008271//secondary active sulfate transmembrane transporter activity","GO:0035725//sodium ion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport","K14444//solute carrier family 13 (sodium/sulfate cotransporter), member 1/4","gi|60460909|ref|NP_001012639.1|//solute carrier family 13 member 4 precursor [Rattus norvegicus];gi|149065251|gb|EDM15327.1|//rCG27983 [Rattus norvegicus]"]
[null,613267,2430,785.435518912466,355.051456533882,1.14546471573885,"UP",0.000433031124038556,"Entpd8","GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0032559//adenyl ribonucleotide binding;GO:0016462//pyrophosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0017110//nucleoside-diphosphatase activity","GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009133//nucleoside diphosphate biosynthetic process;GO:0009132//nucleoside diphosphate metabolic process;GO:0009123//nucleoside monophosphate metabolic process","K01510//apyrase [EC:3.6.1.5]","gi|75677557|ref|NP_001028737.1|//ectonucleoside triphosphate diphosphohydrolase 8 [Rattus norvegicus];gi|564339623|ref|XP_006233704.1|//PREDICTED: ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [Rattus norvegicus]"]
[null,619374,4296,235.848369885332,505.02612559831,-1.09849839269679,"DOWN",0.00677007828412473,"Jam2","GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0043296//apical junction complex;GO:0005886//plasma membrane","GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity","GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion","K06735//junctional adhesion molecule 2","gi|77404265|ref|NP_001029176.1|//junctional adhesion molecule B precursor [Rattus norvegicus]"]
[null,619550,2675,9.65916098402566,22.9279627758301,-1.24713838850942,"DOWN",0.0356739491626107,"Gpr153","GO:0016020//membrane","GO:0004871//signal transducer activity","NA","K08437//G protein-coupled receptor 153","gi|77861912|ref|NP_001030027.1|//probable G-protein coupled receptor 153 [Rattus norvegicus] "]
[null,619558,3123,779.048406698501,1627.6253780046,-1.0629838012478,"DOWN",0.0225191790660549,"Fam134b","GO:0031224//intrinsic component of membrane;GO:0005794//Golgi apparatus;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005801//cis-Golgi network;GO:0044431//Golgi apparatus part","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0007600//sensory perception;GO:0043524//negative regulation of neuron apoptotic process;GO:0019233//sensory perception of pain;GO:0061709//reticulophagy","K12855//pre-mRNA-processing factor 6;K00894//ethanolamine kinase [EC:2.7.1.82];K14816//pre-60S factor REI1","gi|564335666|ref|XP_006232146.1|//PREDICTED: protein FAM134B isoform X4 [Rattus norvegicus];gi|77917608|ref|NP_001030084.1|//reticulophagy receptor FAM134B [Rattus norvegicus]"]
[null,679629,2438,29.8065253876159,76.7267867312279,-1.3641021300309,"DOWN",0.0124416969744679,"Smtnl2","NA","NA","NA","K10314//F-box protein 39;K06115//spectrin beta","gi|300360521|ref|NP_001177927.1|//smoothelin-like protein 2 [Rattus norvegicus]"]
[null,679845,3324,69.3627376653324,16.1404920927922,2.10347627684885,"UP",0.00114659886146461,"Shc4","GO:0044459//plasma membrane part;GO:0030054//cell junction;GO:0045211//postsynaptic membrane","GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding","GO:0048863//stem cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation","K17449//SHC-transforming protein 4","gi|300797114|ref|NP_001177994.1|//SHC-transforming protein 4 [Rattus norvegicus]"]
[null,680308,2061,145.557837337573,39.8648760187942,1.86840243385506,"UP",0.00112879440045999,"Mthfd2","GO:0043231//intracellular membrane-bounded organelle","GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0019238//cyclohydrolase activity","GO:0006760//folic acid-containing compound metabolic process;GO:0006950//response to stress","K13403//methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]","gi|157820897|ref|NP_001102868.1|//bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Rattus norvegicus]"]
[null,680602,2573,167.532050637771,79.7923958736507,1.07011395377969,"UP",0.0126087870683686,"Lcn12","GO:0005576//extracellular region","GO:0001972//retinoic acid binding;GO:0005215//transporter activity","GO:0006810//transport;GO:0051234//establishment of localization","K21129//lipocalin 2;K01830//prostaglandin-H2 D-isomerase [EC:5.3.99.2];K03999//complement component 8 subunit gamma;K11454//chromobox protein 7","gi|108947870|gb|ABG24235.1|//lipocalin 12 [Rattus norvegicus];gi|189458874|ref|NP_001121610.1|//epididymal-specific lipocalin-12 [Rattus norvegicus];gi|328877068|pdb|2L5P|A//Chain A, Solution Nmr Structure Of Protein Lipocalin 12 From Rat Epididymis"]
[null,680611,2133,385.29279619802,856.906768749098,-1.15318303575591,"DOWN",0.00893715483162389,"Bcl3","GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0005654//nucleoplasm;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0032996//Bcl3-Bcl10 complex;GO:0005737//cytoplasm;GO:0033256//I-kappaB/NF-kappaB complex","GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity","GO:0042036//negative regulation of cytokine biosynthetic process;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0000060//protein import into nucleus, translocation;GO:0001819//positive regulation of cytokine production;GO:0045064//T-helper 2 cell differentiation;GO:0002268//follicular dendritic cell differentiation;GO:0006959//humoral immune response;GO:0051101//regulation of DNA binding;GO:0032729//positive regulation of interferon-gamma production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0072595//maintenance of protein localization in organelle;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043066//negative regulation of apoptotic process;GO:0043062//extracellular structure organization;GO:0002313//mature B cell differentiation involved in immune response;GO:0042093//T-helper cell differentiation;GO:0030198//extracellular matrix organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0042348//NF-kappaB import into nucleus;GO:0001562//response to protozoan;GO:0045727//positive regulation of translation;GO:0042742//defense response to bacterium;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0019730//antimicrobial humoral response;GO:0051098//regulation of binding;GO:0010225//response to UV-C;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048536//spleen development;GO:0042088//T-helper 1 type immune response;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002266//follicular dendritic cell activation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042832//defense response to protozoan;GO:0009411//response to UV;GO:0045082//positive regulation of interleukin-10 biosynthetic process;GO:0002467//germinal center formation;GO:0006952//defense response;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0042536//negative regulation of tumor necrosis factor biosynthetic process;GO:0002315//marginal zone B cell differentiation;GO:0045415//negative regulation of interleukin-8 biosynthetic process;GO:0009615//response to virus","K09258//B-cell CLL/lymphoma protein 3","gi|157821585|ref|NP_001102892.1|//B-cell lymphoma 3 protein [Rattus norvegicus];gi|564326672|ref|XP_006228535.1|//PREDICTED: B-cell lymphoma 3 protein isoform X1 [Rattus norvegicus]"]
[null,681337,2561,1992.45995395136,698.133468029539,1.51297594804722,"UP",0.00972500012195237,"Acot4","GO:0042579//microbody","NA","GO:0006732//coenzyme metabolic process;GO:0046459//short-chain fatty acid metabolic process","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","gi|157822089|ref|NP_001102910.1|//acyl-coenzyme A thioesterase 4 [Rattus norvegicus]"]
[null,683626,2634,112.739364697208,261.598507542748,-1.21436296725866,"DOWN",0.00407396933926183,"Lbh","GO:0031981//nuclear lumen","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0032501//multicellular organismal process","K04010//C5a anaphylatoxin chemotactic receptor","gi|672055562|ref|XP_008762755.1|//PREDICTED: protein LBH isoform X1 [Rattus norvegicus]"]
[null,683788,2711,45.8521356536848,103.453597068121,-1.17392297152313,"DOWN",0.00946417251201034,"Fscn1","GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0044459//plasma membrane part;GO:0030427//site of polarized growth;GO:0043005//neuron projection","GO:0003779//actin binding","GO:0007015//actin filament organization;GO:0048513//animal organ development;GO:0048870//cell motility;GO:0031668//cellular response to extracellular stimulus","K17455//fascin 1/2","gi|201066380|ref|NP_001094276.1|//fascin [Rattus norvegicus]"]
[null,684979,1231,6.38208887911922,18.5500783183204,-1.53932467258202,"DOWN",0.0214535757769781,"Hs3st6","GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system","GO:0034483//heparan sulfate sulfotransferase activity","NA","K09679//[heparan sulfate]-glucosamine 3-sulfotransferase 6 [EC:2.8.2.-]","gi|157822283|ref|NP_001102920.1|//heparan sulfate glucosamine 3-O-sulfotransferase 6 [Rattus norvegicus]"]
[null,685545,820,341.33662814277,159.642126998114,1.09635382953521,"UP",0.0256488912839004,"Fam195a","NA","NA","NA","NA","gi|157823085|ref|NP_001102945.1|//protein FAM195A [Rattus norvegicus]"]
[null,689069,2536,35.1876913576174,88.5074568054035,-1.33072814534885,"DOWN",0.00697573750493256,"Parvg","GO:0043232//intracellular non-membrane-bounded organelle;GO:0005924//cell-substrate adherens junction","GO:0008092//cytoskeletal protein binding","GO:0031589//cell-substrate adhesion","K06275//parvin","gi|194474058|ref|NP_001124055.1|//gamma-parvin [Rattus norvegicus]"]
[null,690606,1650,11.8587930532232,28.0345742949522,-1.24124997778043,"DOWN",0.0284443276693651,"Mansc1","GO:0044464//cell part;GO:0016021//integral component of membrane","NA","NA","K03068//low density lipoprotein receptor-related protein 5/6","gi|157819411|ref|NP_001103073.1|//MANSC domain-containing protein 1 precursor [Rattus norvegicus]"]
[null,690899,2976,264.255943259718,606.70590857243,-1.19906144255383,"DOWN",{"v":5.72541560665415e-05,"d":"5.73E-05"},"Vsir","GO:0031224//intrinsic component of membrane;GO:0009897//external side of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane","GO:0005515//protein binding;GO:0004871//signal transducer activity","GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:0023052//signaling;GO:0030513//positive regulation of BMP signaling pathway;GO:0002725//negative regulation of T cell cytokine production;GO:2000738//positive regulation of stem cell differentiation","NA","gi|112983748|ref|NP_001037765.1|//platelet receptor Gi24 [Rattus norvegicus];gi|149038759|gb|EDL93048.1|//rCG22135, isoform CRA_a [Rattus norvegicus]"]
[null,690955,2499,17.4396583355456,42.3995616920534,-1.28167757470795,"DOWN",0.0231386347489869,"Lilrb3b","NA","NA","NA","K06512//leukocyte immunoglobulin-like receptor","gi|927261919|ref|NP_001300853.1|//leukocyte immunoglobulin-like receptor subfamily B member 3-like precursor [Rattus norvegicus]"]
[null,691533,3798,118.905536708439,259.833938778147,-1.12777398967082,"DOWN",0.0210288444509527,"Lilra5","GO:0009986//cell surface;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0050839//cell adhesion molecule binding;GO:0042288//MHC class I protein binding;GO:0023029//MHC class Ib protein binding;GO:0032396//inhibitory MHC class I receptor activity;GO:0008157//protein phosphatase 1 binding","GO:0045591//positive regulation of regulatory T cell differentiation;GO:0002578//negative regulation of antigen processing and presentation;GO:0071222//cellular response to lipopolysaccharide;GO:0042102//positive regulation of T cell proliferation;GO:0051926//negative regulation of calcium ion transport;GO:0042130//negative regulation of T cell proliferation;GO:0002666//positive regulation of T cell tolerance induction;GO:0034113//heterotypic cell-cell adhesion;GO:0002774//Fc receptor mediated inhibitory signaling pathway","K06512//leukocyte immunoglobulin-like receptor;K12822//RNA-binding protein 25","gi|946795252|ref|XP_014383599.1|//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X1 [Myotis brandtii];gi|946795254|ref|XP_014383600.1|//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2 [Myotis brandtii];gi|672035221|ref|XP_008757210.1|//PREDICTED: leukocyte immunoglobulin-like receptor subfamily A member 5 isoform X1 [Rattus norvegicus];gi|153945844|ref|NP_001070261.1|//leukocyte immunoglobulin-like receptor subfamily A member 5 precursor [Rattus norvegicus]"]
[null,100125372,1935,1172.33537029822,353.620734296234,1.72911056726317,"UP",0.0010139174105534,"Ces1f","GO:0044432//endoplasmic reticulum part","NA","GO:0051969//regulation of transmission of nerve impulse","K01044//carboxylesterase 1 [EC:3.1.1.1]","gi|386781527|ref|NP_001096829.2|//liver carboxylesterase 4 precursor [Rattus norvegicus]"]
[null,100188935,1617,4879.67871746832,10784.4281893667,-1.14409161646587,"DOWN",0.00276083236136764,"RT1-A","GO:0031224//intrinsic component of membrane;GO:0042611//MHC protein complex","GO:0005488//binding","GO:0048002//antigen processing and presentation of peptide antigen","K06751//major histocompatibility complex, class I","gi|197927431|ref|NP_001128173.1|//RT1 class I, locus A precursor [Rattus norvegicus]"]
[null,100360757,3202,95.9309897199191,248.543593056461,-1.37343006758678,"DOWN",0.00260642606896944,"Ctcfl","GO:0043231//intracellular membrane-bounded organelle","GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046914//transition metal ion binding","GO:0031060//regulation of histone methylation;GO:0006351//transcription, DNA-templated;GO:0006306//DNA methylation","K09228//KRAB domain-containing zinc finger protein","gi|223462331|gb|AAI51027.1|//Ctcfl protein [Mus musculus];gi|532040659|ref|XP_005363178.1|//PREDICTED: transcriptional repressor CTCFL [Microtus ochrogaster]"]
[null,100361323,4229,10.0765513959388,33.6232111577996,-1.73845553995975,"DOWN",0.00492713024906316,"Astn2","NA","NA","NA","K14480//apolipoprotein L","gi|405113055|ref|NP_001258292.1|//astrotactin-2 precursor [Rattus norvegicus]"]
[null,100363423,902,21.9329063097745,8.51194002391606,1.36553710430997,"UP",0.0296784733434878,"LOC100363423","NA","NA","NA","NA","gi|149053857|gb|EDM05674.1|//rCG35357 [Rattus norvegicus]"]
[null,100365921,1510,120.557482570283,57.3968270801572,1.07067830517111,"UP",0.00958295388974035,"LOC100365921","GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043234//protein complex","NA","GO:0006497//protein lipidation","K11001//phosphatidylinositol glycan anchor biosynthesis, class Y","gi|354475081|ref|XP_003499758.1|//PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit Y [Cricetulus griseus]"]
[null,100912041,1231,679.653040270247,322.432147373067,1.07580285344281,"UP",{"v":3.58050341654055e-05,"d":"3.58E-05"},"LOC100912041","NA","NA","NA","NA","gi|149062282|gb|EDM12705.1|//rCG47316, isoform CRA_b [Rattus norvegicus];gi|149062281|gb|EDM12704.1|//rCG47316, isoform CRA_a [Rattus norvegicus];gi|149062285|gb|EDM12708.1|//rCG47316, isoform CRA_d [Rattus norvegicus]"]
[null,100912083,726,30.6038014385551,13.7736790054311,1.15179690718425,"UP",0.039969652450614,"Dancr","NA","NA","NA","NA","gi|26337233|dbj|BAC32301.1|//unnamed protein product [Mus musculus]"]
[null,106631776,445,385.458869919901,189.765780839449,1.02235706221461,"UP",0.0112404616761492,"LOC106631776","GO:0016020//membrane","NA","NA","NA","gi|81897387|sp|Q8BT35.1|YB039_MOUSE//RecName: Full=Uncharacterized protein LINC00116 homolog"]
[null,"BGI_novel_G000018",2401,13.3866549768079,42.0836980064103,-1.65246597491,"DOWN",0.00721370067667684,"NA","NA","NA","NA","K05637//laminin, alpha 1/2","gi|672012502|ref|XP_008772505.1|//PREDICTED: laminin subunit alpha-2 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G000026",6047,16.1173846237063,49.1144921157254,-1.60753112452763,"DOWN",0.0220618740157504,"NA","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0019898//extrinsic component of membrane;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042731//PH domain binding;GO:0030507//spectrin binding","GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape","K06107//erythrocyte membrane protein band 4.1","gi|293343505|ref|XP_001053351.2|//PREDICTED: band 4.1-like protein 2 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G000028",5565,12.8968192982825,38.3698306879053,-1.57295709666056,"DOWN",0.0252288289889291,"NA","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0019898//extrinsic component of membrane;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042731//PH domain binding;GO:0030507//spectrin binding","GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape","K06107//erythrocyte membrane protein band 4.1","gi|293343505|ref|XP_001053351.2|//PREDICTED: band 4.1-like protein 2 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G000056",2361,15.4842455227125,39.0550377198167,-1.33470756527415,"DOWN",0.0275926234325108,"NA","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K13705//abhydrolase domain-containing protein 12B;K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-]","gi|913509427|ref|XP_013207771.1|//PREDICTED: protein unc-93 homolog A [Microtus ochrogaster]"]
[null,"BGI_novel_G000085",5683,6.26719667146511,19.5597283791737,-1.64199416380834,"DOWN",0.0159661996484212,"NA","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","gi|148706141|gb|EDL38088.1|//zinc finger protein 446 [Mus musculus]"]
[null,"BGI_novel_G000092",5382,52.6873204435972,119.020366328535,-1.17568074881564,"DOWN",0.0351306302131818,"NA","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","gi|148706141|gb|EDL38088.1|//zinc finger protein 446 [Mus musculus]"]
[null,"BGI_novel_G000122",3882,49.5072705126128,170.412013091581,-1.78331472465022,"DOWN",{"v":2.27649870546779e-05,"d":"2.28E-05"},"NA","GO:0016021//integral component of membrane","NA","GO:0045671//negative regulation of osteoclast differentiation","K06512//leukocyte immunoglobulin-like receptor","gi|392337441|ref|XP_001070618.3|//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000136",6135,9.37739422317131,34.6773546980091,-1.88673485974416,"DOWN",0.00640368584317017,"NA","NA","GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding","NA","K06237//collagen, type IV, alpha;K19475//WAS/WASL-interacting protein","gi|392343941|ref|XP_001053214.2|//PREDICTED: zinc finger CCCH domain-containing protein 4 isoform X7 [Rattus norvegicus]"]
[null,"BGI_novel_G000141",2900,31.2633103622089,8.79243471557935,1.83013592544526,"UP",0.00800715248668559,"NA","GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0031307//integral component of mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0033017//sarcoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0031072//heat shock protein binding;GO:0017020//myosin phosphatase regulator activity","GO:0014722//regulation of skeletal muscle contraction by calcium ion signaling;GO:0002028//regulation of sodium ion transport;GO:0050790//regulation of catalytic activity;GO:0051823//regulation of synapse structural plasticity;GO:0014853//regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction;GO:0010830//regulation of myotube differentiation;GO:0018105//peptidyl-serine phosphorylation;GO:0010657//muscle cell apoptotic process;GO:0008016//regulation of heart contraction;GO:0006874//cellular calcium ion homeostasis;GO:0006998//nuclear envelope organization","K08788//dystrophia myotonica-protein kinase [EC:2.7.11.1]","gi|564296955|ref|XP_006223172.1|//PREDICTED: myotonin-protein kinase isoform X8 [Rattus norvegicus]"]
[null,"BGI_novel_G000166",8251,14.4515831648104,56.2103246189959,-1.95960759859914,"DOWN",0.0047492945563445,"NA","GO:0005634//nucleus;GO:0043234//protein complex","GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048286//lung alveolus development","K20225//capicua transcriptional repressor","gi|755520084|ref|XP_011248998.1|//PREDICTED: protein capicua homolog isoform X1 [Mus musculus]"]
[null,"BGI_novel_G000168",5612,2.50401386489746,101.78973479964,-5.34520571630712,"DOWN",{"v":1.38695564582871e-17,"d":"1.39E-17"},"NA","GO:0005634//nucleus;GO:0043234//protein complex","GO:0003682//chromatin binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048286//lung alveolus development","K20225//capicua transcriptional repressor","gi|672035060|ref|XP_008757160.1|//PREDICTED: protein capicua homolog isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G000195",3464,71.5170147679708,2.44702228054036,4.86918737486567,"UP",{"v":2.68667675671049e-14,"d":"2.69E-14"},"NA","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0015031//protein transport","K17933//Rho GTPase-activating protein 33","gi|672036086|ref|XP_008757475.1|//PREDICTED: rho GTPase-activating protein 33 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G000197",4031,69.2524394071233,20.4242558213193,1.76158137752317,"UP",0.000171022071251077,"NA","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005515//protein binding;GO:0005096//GTPase activator activity","NA","K17933//Rho GTPase-activating protein 33","gi|913506920|ref|XP_013206994.1|//PREDICTED: rho GTPase-activating protein 33 isoform X1 [Microtus ochrogaster]"]
[null,"BGI_novel_G000211",1593,10.7399016852928,29.3906556933868,-1.45237675854654,"DOWN",0.0153560083801341,"NA","GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding","GO:0007155//cell adhesion","K06473//CD33 antigen;K06549//sialic acid binding Ig-like lectin 5/14","gi|149056119|gb|EDM07550.1|//rCG54544 [Rattus norvegicus]"]
[null,"BGI_novel_G000225",736,1371.27326398237,392.17184347991,1.80595823243179,"UP",{"v":2.35804020946013e-06,"d":"2.36E-06"},"NA","GO:0016324//apical plasma membrane;GO:0060171//stereocilium membrane;GO:0005737//cytoplasm","GO:0008199//ferric iron binding","GO:0006879//cellular iron ion homeostasis;GO:0007605//sensory perception of sound;GO:0048741//skeletal muscle fiber development","K13625//ferritin light chain","gi|204131|gb|AAA41154.1|//ferritin light chain subunit [Rattus norvegicus]"]
[null,"BGI_novel_G000226",2542,346.321574847127,97.8287581614467,1.82378173266308,"UP",{"v":4.40249959151956e-05,"d":"4.40E-05"},"NA","GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0008043//intracellular ferritin complex;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0008199//ferric iron binding","GO:0006879//cellular iron ion homeostasis;GO:0006826//iron ion transport;GO:0010288//response to lead ion","K13625//ferritin light chain","gi|84000579|ref|NP_071945.3|//ferritin light chain 1 [Rattus norvegicus]"]
[null,"BGI_novel_G000255",3687,10.3787510310999,28.8086221236631,-1.47286781844036,"DOWN",0.0368230711663459,"NA","NA","NA","NA","K12869//crooked neck","gi|564297757|ref|XP_006223409.1|//PREDICTED: protein FAM169B isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000259",1765,17.0065945238939,39.4081776486015,-1.21240075825454,"DOWN",0.0195827794924212,"NA","GO:0016021//integral component of membrane","NA","NA","K10364//capping protein (actin filament) muscle Z-line, alpha","gi|149057193|gb|EDM08516.1|//rCG24730 [Rattus norvegicus]"]
[null,"BGI_novel_G000260",3403,73.8312347501727,28.3533955514655,1.38070976621692,"UP",0.0080006569150493,"NA","NA","NA","NA","K10591//E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]","gi|67983666|ref|XP_669208.1|//hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]"]
[null,"BGI_novel_G000292",1597,7.27925286520335,23.4889970108209,-1.69012282458803,"DOWN",0.011580509265892,"NA","NA","NA","GO:0051260//protein homooligomerization","K15074//BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K20131//Rab5 GDP/GTP exchange factor","gi|564298020|ref|XP_006223473.1|//PREDICTED: BTB/POZ domain-containing protein KCTD14 [Rattus norvegicus]"]
[null,"BGI_novel_G000369",466,4.35222301565167,25.3850655155209,-2.54415559362277,"DOWN",0.000250489315668161,"NA","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity;GO:0035375//zymogen binding","GO:0010033//response to organic substance;GO:0006898//receptor-mediated endocytosis;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0042246//tissue regeneration;GO:0015031//protein transport;GO:0043627//response to estrogen","K13912//deleted in malignant brain tumors 1 protein","gi|672038788|ref|XP_008758187.1|//PREDICTED: deleted in malignant brain tumors 1 protein isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G000370",436,7.84692048007289,23.7055272226271,-1.59502499441421,"DOWN",0.0119511374450557,"NA","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity;GO:0035375//zymogen binding","GO:0010033//response to organic substance;GO:0006898//receptor-mediated endocytosis;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0042246//tissue regeneration;GO:0015031//protein transport;GO:0043627//response to estrogen","K13912//deleted in malignant brain tumors 1 protein","gi|672038788|ref|XP_008758187.1|//PREDICTED: deleted in malignant brain tumors 1 protein isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G000371",3192,111.389297215946,257.47071762158,-1.20879774389222,"DOWN",0.00112665101490073,"NA","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity;GO:0035375//zymogen binding","GO:0010033//response to organic substance;GO:0006898//receptor-mediated endocytosis;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0042246//tissue regeneration;GO:0015031//protein transport;GO:0043627//response to estrogen","K13912//deleted in malignant brain tumors 1 protein","gi|975347|gb|AAC52248.1|//ebnerin [Rattus norvegicus]"]
[null,"BGI_novel_G000379",1410,36.0842091157269,101.250049488238,-1.48848307353748,"DOWN",0.00778723635272881,"NA","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity;GO:0035375//zymogen binding","GO:0010033//response to organic substance;GO:0006898//receptor-mediated endocytosis;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0042246//tissue regeneration;GO:0015031//protein transport;GO:0043627//response to estrogen","K13912//deleted in malignant brain tumors 1 protein","gi|672014845|ref|XP_006223754.2|//PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein-like isoform X6, partial [Rattus norvegicus]"]
[null,"BGI_novel_G000383",1338,32.2285391580213,93.1093981090432,-1.53058799930069,"DOWN",0.0269284839772851,"NA","GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0035375//zymogen binding","GO:0006810//transport;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation","K13912//deleted in malignant brain tumors 1 protein","gi|672014845|ref|XP_006223754.2|//PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein-like isoform X6, partial [Rattus norvegicus]"]
[null,"BGI_novel_G000386",898,31.9102196410131,85.5795370711659,-1.42324733609846,"DOWN",0.0412842105987419,"NA","GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005578//proteinaceous extracellular matrix","GO:0035375//zymogen binding","GO:0006810//transport;GO:0030858//positive regulation of epithelial cell differentiation;GO:0001833//inner cell mass cell proliferation","K13912//deleted in malignant brain tumors 1 protein","gi|672014845|ref|XP_006223754.2|//PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein-like isoform X6, partial [Rattus norvegicus]"]
[null,"BGI_novel_G000397",3070,48.9705371583003,142.113596352688,-1.5370586611378,"DOWN",0.0136981927881184,"NA","GO:0032010//phagolysosome;GO:0032127//dense core granule membrane;GO:0042581//specific granule;GO:0071133//alpha9-beta1 integrin-ADAM8 complex;GO:0070820//tertiary granule;GO:0009986//cell surface;GO:0071065//alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex;GO:0005887//integral component of plasma membrane;GO:0002102//podosome","GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","GO:0071456//cellular response to hypoxia;GO:0002675//positive regulation of acute inflammatory response;GO:0051897//positive regulation of protein kinase B signaling;GO:0043534//blood vessel endothelial cell migration;GO:2000309//positive regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:0002523//leukocyte migration involved in inflammatory response;GO:0061025//membrane fusion;GO:2000415//positive regulation of fibronectin-dependent thymocyte migration;GO:0048247//lymphocyte chemotaxis;GO:0000902//cell morphogenesis;GO:0001525//angiogenesis;GO:0048729//tissue morphogenesis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0043524//negative regulation of neuron apoptotic process;GO:0033089//positive regulation of T cell differentiation in thymus;GO:2000399//negative regulation of thymocyte aggregation;GO:0072675//osteoclast fusion;GO:0045780//positive regulation of bone resorption;GO:0007160//cell-matrix adhesion;GO:2000391//positive regulation of neutrophil extravasation;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0045670//regulation of osteoclast differentiation;GO:2000418//positive regulation of eosinophil migration;GO:0035419//activation of MAPK activity involved in innate immune response","K06540//disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]","gi|564298577|ref|XP_006223620.1|//PREDICTED: disintegrin and metalloproteinase domain-containing protein 8 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G000406",590,1.76705612472997,5.39843473026569,-1.61119329711228,"DOWN",0.0187684995104574,"NA","GO:0016021//integral component of membrane","NA","NA","K06566//interferon induced transmembrane protein","gi|149061536|gb|EDM11959.1|//rCG47837 [Rattus norvegicus]"]
[null,"BGI_novel_G000417",3953,11.0238761165837,30.6818037758573,-1.47675172040916,"DOWN",0.0274089967537087,"NA","GO:0016021//integral component of membrane","NA","GO:0055085//transmembrane transport","K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","gi|149061627|gb|EDM12050.1|//rCG47744, isoform CRA_c [Rattus norvegicus]"]
[null,"BGI_novel_G000458",9367,9.75907669574299,38.6034541418192,-1.98391337578783,"DOWN",0.0043284001413919,"NA","GO:0016021//integral component of membrane","NA","NA","NA","gi|564298773|ref|XP_006223686.1|//PREDICTED: pecanex-like protein 3 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G000480",2526,108.496095076082,274.87304858412,-1.34112233791878,"DOWN",0.00622175288326327,"NA","GO:0016021//integral component of membrane","NA","NA","K08090//membrane-spanning 4-domains, subfamily A, member 2","gi|672014692|ref|XP_001075502.5|//PREDICTED: membrane-spanning 4-domains subfamily A member 6D [Rattus norvegicus]"]
[null,"BGI_novel_G000490",2363,13.4359639935792,38.2329640440374,-1.50871721622714,"DOWN",0.0066579961154623,"NA","NA","NA","NA","K01316//enterokinase [EC:3.4.21.9]","gi|672040032|ref|XP_008758538.1|//PREDICTED: MAM domain-containing protein 2 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G000528",1358,19.8816671588707,7.50655443451311,1.40521598102929,"UP",0.0285632313288387,"NA","GO:0005739//mitochondrion","GO:0017084//delta1-pyrroline-5-carboxylate synthetase activity;GO:0044822//poly(A) RNA binding;GO:0004350//glutamate-5-semialdehyde dehydrogenase activity;GO:0042802//identical protein binding;GO:0004349//glutamate 5-kinase activity","GO:0006561//proline biosynthetic process;GO:0006536//glutamate metabolic process;GO:0006592//ornithine biosynthetic process;GO:0016310//phosphorylation;GO:0019240//citrulline biosynthetic process;GO:0055114//oxidation-reduction process","K12657//delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41]","gi|392345077|ref|XP_003749156.1|//PREDICTED: delta-1-pyrroline-5-carboxylate synthase isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000535",4437,316.300861920788,154.164489918202,1.03682699250472,"UP",0.0461749279019995,"NA","NA","NA","NA","K14794//ribosomal RNA-processing protein 12","gi|625291828|ref|XP_007637668.1|//PREDICTED: RRP12-like protein isoform X2 [Cricetulus griseus]"]
[null,"BGI_novel_G000549",891,272.393464499867,91.3340799127528,1.57646690404164,"UP",0.000334293727861619,"NA","NA","NA","NA","K10591//E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]","gi|149040391|gb|EDL94429.1|//rCG57764, partial [Rattus norvegicus]"]
[null,"BGI_novel_G000561",5058,205.861018603918,77.2479938929737,1.41410129796482,"UP",0.000132366671428192,"NA","NA","NA","NA","NA","gi|293344794|ref|XP_001064355.2|//PREDICTED: protein FAM160B1 [Rattus norvegicus]"]
[null,"BGI_novel_G000565",4632,34.0543555287072,82.4840363101866,-1.27627560216417,"DOWN",0.00437802061445147,"NA","NA","NA","NA","K05636//laminin, beta 1;K10895//fanconi anemia group I protein","gi|672040941|ref|XP_008758809.1|//PREDICTED: attractin-like protein 1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000600",1723,29.1430984164883,10.5399100131139,1.46729171935553,"UP",0.0283246674385545,"NA","NA","NA","NA","K14775//ribosome biogenesis protein UTP30","gi|672066617|ref|XP_008765724.1|//PREDICTED: ribosomal L1 domain-containing protein 1 [Rattus norvegicus]"]
[null,"BGI_novel_G000601",5848,86.5993207337359,33.7003965772479,1.36159014005364,"UP",0.0245705350125454,"NA","NA","NA","NA","K19513//protein CLEC16A","gi|672066640|ref|XP_008765731.1|//PREDICTED: protein CLEC16A isoform X7 [Rattus norvegicus]"]
[null,"BGI_novel_G000634",7595,145.682108045297,66.4586325271955,1.1322951905041,"UP",0.038401883323119,"NA","NA","NA","NA","K11137//telomere length regulation protein","gi|62655853|ref|XP_220236.3|//PREDICTED: telomere length regulation protein TEL2 homolog [Rattus norvegicus]"]
[null,"BGI_novel_G000656",4887,236.810556567691,90.0212872480347,1.39539529540333,"UP",0.0169533186942201,"NA","NA","NA","NA","K16685//protein KIBRA","gi|672024676|ref|XP_008772972.1|//PREDICTED: protein KIBRA isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G000658",3080,13.1524424933026,34.647900829698,-1.39743720603629,"DOWN",0.0254805719272173,"NA","GO:0016021//integral component of membrane","GO:0001786//phosphatidylserine binding","NA","K21125//mucin-5AC","gi|672024712|ref|XP_006220700.2|//PREDICTED: T-cell immunoglobulin and mucin domain-containing protein 4 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G000659",2135,15.2942550785226,54.8504896959692,-1.84251466007445,"DOWN",0.00722817834074354,"NA","GO:0016021//integral component of membrane","GO:0001786//phosphatidylserine binding","NA","K21125//mucin-5AC","gi|672024710|ref|XP_006220699.2|//PREDICTED: T-cell immunoglobulin and mucin domain-containing protein 4 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G000660",3080,13.1524424933026,34.647900829698,-1.39743720603629,"DOWN",0.0254805719272173,"NA","GO:0016021//integral component of membrane","GO:0001786//phosphatidylserine binding","NA","K21125//mucin-5AC","gi|672024712|ref|XP_006220700.2|//PREDICTED: T-cell immunoglobulin and mucin domain-containing protein 4 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G000707",7302,4.01812789768582,158.34783238493,-5.30042982227267,"DOWN",{"v":5.6178375929581e-20,"d":"5.62E-20"},"NA","NA","NA","NA","K11642//chromodomain-helicase-DNA-binding protein 3 [EC:3.6.4.12]","gi|672068312|ref|XP_008766146.1|//PREDICTED: chromodomain-helicase-DNA-binding protein 3 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000709",8257,249.489002372701,117.545532898151,1.08575650902702,"UP",0.000851365200958893,"NA","NA","NA","NA","K11642//chromodomain-helicase-DNA-binding protein 3 [EC:3.6.4.12]","gi|672068312|ref|XP_008766146.1|//PREDICTED: chromodomain-helicase-DNA-binding protein 3 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000722",9930,10.6551061943018,45.3935461842826,-2.09094222546309,"DOWN",0.00291717172426774,"NA","NA","GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","NA","K10595//E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]","gi|564312952|ref|XP_006220785.1|//PREDICTED: zinc finger ZZ-type and EF-hand domain-containing protein 1 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G000772",5167,52.2550495056306,113.091819877052,-1.11385222109437,"DOWN",0.00339826930156794,"NA","GO:0070062//extracellular exosome","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity","K20315//Rho GTPase-activating protein 21/23","gi|564374479|ref|XP_006247499.1|//PREDICTED: rho GTPase-activating protein 23 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G000782",2123,44.7705403456996,140.636132306302,-1.6513456643042,"DOWN",0.00384956749076687,"NA","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane","GO:0001791//IgM binding","GO:0002414//immunoglobulin transcytosis in epithelial cells;GO:0002376//immune system process","K16663//CMRF35-like molecule 9","gi|149054349|gb|EDM06166.1|//rCG33868 [Rattus norvegicus]"]
[null,"BGI_novel_G000822",8007,289.839257172145,16.3691884213594,4.14619831304937,"UP",{"v":1.32382422695389e-10,"d":"1.32E-10"},"NA","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances","GO:0006869//lipid transport","K05649//ATP-binding cassette, subfamily A (ABC1), member 6","gi|262118230|ref|NP_671751.2|//ATP-binding cassette sub-family A member 6 isoform 1 [Mus musculus]"]
[null,"BGI_novel_G000872",5079,34.5103783162873,81.8054492949365,-1.24516665916232,"DOWN",0.0116873226058687,"NA","GO:0005737//cytoplasm","GO:0050700//CARD domain binding","GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0001934//positive regulation of protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0033209//tumor necrosis factor-mediated signaling pathway","K20913//caspase recruitment domain-containing protein 14","gi|149054969|gb|EDM06786.1|//rCG34191, partial [Rattus norvegicus]"]
[null,"BGI_novel_G000910",8171,25.5480598171788,69.4912474254924,-1.44361754518984,"DOWN",0.040656003918487,"NA","GO:0005634//nucleus;GO:0005829//cytosol","GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0001078//transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding","GO:0031062//positive regulation of histone methylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000288//positive regulation of myoblast proliferation;GO:0014842//regulation of skeletal muscle satellite cell proliferation","K13211//GC-rich sequence DNA-binding factor","gi|109492822|ref|XP_001057305.1|//PREDICTED: PAX3- and PAX7-binding protein 1 [Rattus norvegicus]"]
[null,"BGI_novel_G000913",4629,120.001703735491,53.6405037025131,1.1616601989638,"UP",0.034467111103207,"NA","GO:0005634//nucleus;GO:0005829//cytosol","GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0001078//transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding","GO:0031062//positive regulation of histone methylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000288//positive regulation of myoblast proliferation;GO:0014842//regulation of skeletal muscle satellite cell proliferation","K13211//GC-rich sequence DNA-binding factor","gi|109492822|ref|XP_001057305.1|//PREDICTED: PAX3- and PAX7-binding protein 1 [Rattus norvegicus]"]
[null,"BGI_novel_G000944",533,2.638453579327,7.88290797078634,-1.57903533072383,"DOWN",0.0204098894923135,"NA","GO:0000793//condensed chromosome;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0048471//perinuclear region of cytoplasm","GO:0031493//nucleosomal histone binding;GO:0044822//poly(A) RNA binding;GO:0050786//RAGE receptor binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0044378//non-sequence-specific DNA binding, bending;GO:0008289//lipid binding;GO:0003697//single-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0019904//protein domain specific binding;GO:0008144//drug binding;GO:0097100//supercoiled DNA binding;GO:0042056//chemoattractant activity;GO:0008134//transcription factor binding;GO:0003700//transcription factor activity, sequence-specific DNA binding","GO:0031100//animal organ regeneration;GO:0050829//defense response to Gram-negative bacterium;GO:0072091//regulation of stem cell proliferation;GO:0045089//positive regulation of innate immune response;GO:0071222//cellular response to lipopolysaccharide;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0051054//positive regulation of DNA metabolic process;GO:0008584//male gonad development;GO:0032075//positive regulation of nuclease activity;GO:0060326//cell chemotaxis;GO:0001938//positive regulation of endothelial cell proliferation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0050830//defense response to Gram-positive bacterium;GO:0006265//DNA topological change;GO:0043388//positive regulation of DNA binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0032728//positive regulation of interferon-beta production;GO:0007289//spermatid nucleus differentiation;GO:0048545//response to steroid hormone;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045648//positive regulation of erythrocyte differentiation;GO:0006310//DNA recombination;GO:0050767//regulation of neurogenesis;GO:0002437//inflammatory response to antigenic stimulus","K11295//high mobility group protein B2","gi|625292335|ref|XP_007637920.1|//PREDICTED: high mobility group protein B2 isoform X2 [Cricetulus griseus]"]
[null,"BGI_novel_G000998",3229,1556.59765139293,4269.77612324905,-1.45576434165424,"DOWN",0.00422895748131753,"NA","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005829//cytosol","GO:0005102//receptor binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0030195//negative regulation of blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:0007162//negative regulation of cell adhesion;GO:0006953//acute-phase response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042311//vasodilation","K03898//kininogen","gi|205085|gb|AAA41489.1|//LMW T-kininogen I precursor [Rattus norvegicus]"]
[null,"BGI_novel_G001003",5319,33.4963903070674,122.694848620786,-1.87299713930679,"DOWN",{"v":1.98309326782633e-05,"d":"1.98E-05"},"NA","NA","NA","NA","NA","gi|293340917|ref|XP_001058431.2|//PREDICTED: UPF0524 protein C3orf70 homolog [Rattus norvegicus]"]
[null,"BGI_novel_G001017",1375,170.502159267697,81.8417994538614,1.058880238846,"UP",0.0474980526917985,"NA","GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0030659//cytoplasmic vesicle membrane","GO:0043803//hydroxyneurosporene-O-methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0034541//dimethylarsinite methyltransferase activity;GO:0052665//tRNA (uracil-2'-O-)-methyltransferase activity;GO:0052667//phosphomethylethanolamine N-methyltransferase activity;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity;GO:0043782//cobalt-precorrin-3 C17-methyltransferase activity;GO:0043770//demethylmenaquinone methyltransferase activity;GO:0016205//selenocysteine methyltransferase activity;GO:0008988//rRNA (adenine-N6-)-methyltransferase activity;GO:0043777//cobalt-precorrin-7 C15-methyltransferase activity;GO:0019702//protein-arginine N5-methyltransferase activity;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0070677//rRNA (cytosine-2'-O-)-methyltransferase activity;GO:0008650//rRNA (uridine-2'-O-)-methyltransferase activity;GO:0080012//trihydroxyferuloyl spermidine O-methyltransferase activity;GO:0034807//4,5-dihydroxybenzo(a)pyrene methyltransferase activity;GO:0043780//cobalt-precorrin-5B C1-methyltransferase activity;GO:0043776//cobalt-precorrin-6B C5-methyltransferase activity;GO:0052624//2-phytyl-1,4-naphthoquinone methyltransferase activity;GO:0004222//metalloendopeptidase activity;GO:0034931//1-hydroxypyrene methyltransferase activity;GO:0018423//protein C-terminal leucine carboxyl O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0043834//trimethylamine methyltransferase activity;GO:0008174//mRNA methyltransferase activity;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0034933//1-hydroxy-6-methoxypyrene methyltransferase activity;GO:0051994//P-methyltransferase activity;GO:0043791//dimethylamine methyltransferase activity;GO:0043851//methanol-specific methylcobalamin:coenzyme M methyltransferase activity;GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0052666//tRNA (cytosine-2'-O-)-methyltransferase activity;GO:0043827//tRNA (adenine-57, 58-N(1)-) methyltransferase activity;GO:0043833//methylamine-specific methylcobalamin:coenzyme M methyltransferase activity;GO:0008172//S-methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0046872//metal ion binding;GO:0043852//monomethylamine methyltransferase activity;GO:0018707//1-phenanthrol methyltransferase activity;GO:0030792//methylarsonite methyltransferase activity;GO:0009383//rRNA (cytosine-C5-)-methyltransferase activity;GO:0071424//rRNA (cytosine-N4-)-methyltransferase activity","GO:0016486//peptide hormone processing;GO:0032259//methylation","K01415//endothelin-converting enzyme [EC:3.4.24.71]","gi|564377512|ref|XP_006248650.1|//PREDICTED: endothelin-converting enzyme 2 [Rattus norvegicus]"]
[null,"BGI_novel_G001057",5754,2.38178959014885,17.8515133281221,-2.90592850645536,"DOWN",{"v":3.51524908647935e-05,"d":"3.52E-05"},"NA","NA","NA","NA","K12572//PAB-dependent poly(A)-specific ribonuclease subunit 3","gi|564378170|ref|XP_006248906.1|//PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G001083",2930,26.7936888644499,10.7912475499447,1.31203155928713,"UP",0.0324289828363786,"NA","NA","NA","NA","K18743//caprin-1;K12893//splicing factor, arginine/serine-rich 4/5/6","gi|585685077|ref|XP_006820074.1|//PREDICTED: mucin-19-like [Saccoglossus kowalevskii]"]
[null,"BGI_novel_G001114",880,44.1420768795337,109.143376354344,-1.30599816437812,"DOWN",0.0147071914225959,"NA","NA","NA","NA","K15411//paired immunoglobulin-like type 2 receptor alpha","gi|672072818|ref|XP_008767401.1|//PREDICTED: paired immunoglobulin-like type 2 receptor alpha [Rattus norvegicus]"]
[null,"BGI_novel_G001125",2469,99.7951741063111,37.4128453767669,1.41543635939455,"UP",0.00598180929086401,"NA","NA","NA","NA","K01376//UFM1-specific protease 2 [EC:3.4.22.-]","gi|928136440|ref|XP_013969675.1|//PREDICTED: serrate RNA effector molecule homolog isoform X2 [Canis lupus familiaris]"]
[null,"BGI_novel_G001157",2378,26.129274519568,7.60324630144962,1.78097963676086,"UP",0.00967294142179468,"NA","GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle;GO:0005802//trans-Golgi network;GO:0055037//recycling endosome;GO:0005769//early endosome","GO:0042803//protein homodimerization activity","GO:0001881//receptor recycling;GO:0042147//retrograde transport, endosome to Golgi;GO:0007032//endosome organization","K04349//Ras-specific guanine nucleotide-releasing factor 1","gi|325530254|sp|D3ZL52.1|SESQ1_RAT//RecName: Full=Sesquipedalian-1; Short=Ses1; AltName: Full=27 kDa inositol polyphosphate phosphatase interacting protein A; Short=IPIP27A"]
[null,"BGI_novel_G001159",4986,136.576315085442,22.5233367773226,2.60021483461963,"UP",{"v":5.36774708329839e-05,"d":"5.37E-05"},"NA","GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005802//trans-Golgi network;GO:0048471//perinuclear region of cytoplasm;GO:0005844//polysome","GO:0050692//DBD domain binding;GO:0044822//poly(A) RNA binding;GO:0008022//protein C-terminus binding;GO:0005154//epidermal growth factor receptor binding","GO:0048872//homeostasis of number of cells;GO:0034063//stress granule assembly;GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0048812//neuron projection morphogenesis;GO:0021702//cerebellar Purkinje cell differentiation;GO:0040015//negative regulation of multicellular organism growth;GO:0050905//neuromuscular process;GO:0002091//negative regulation of receptor internalization","K13172//serine/arginine repetitive matrix protein 2","gi|672026757|ref|XP_008758699.1|//PREDICTED: ataxin-2 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G001205",320,46.5533152912248,15.093156516312,1.62498935656412,"UP",0.00319934268509987,"NA","GO:0016020//membrane;GO:0032040//small-subunit processome;GO:0031428//box C/D snoRNP complex;GO:0070761//pre-snoRNP complex","GO:0030515//snoRNA binding;GO:1990226//histone methyltransferase binding;GO:0044822//poly(A) RNA binding","GO:0000154//rRNA modification","K14564//nucleolar protein 56","gi|55824708|gb|AAH86568.1|//Nol5a protein, partial [Rattus norvegicus]"]
[null,"BGI_novel_G001209",1023,13.1700518222358,35.141279718333,-1.41590570763892,"DOWN",0.0150153468525669,"NA","GO:0016021//integral component of membrane","NA","NA","K06551//signal-regulatory protein alpha/beta1/gamma","gi|672073886|ref|XP_008767725.1|//PREDICTED: tyrosine-protein phosphatase non-receptor type substrate 1-like isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G001249",435,16.0910054488624,6.567728932853,1.29278798618736,"UP",0.0482676350703706,"NA","NA","NA","NA","K03231//elongation factor 1-alpha","gi|344250492|gb|EGW06596.1|//Elongation factor 1-alpha 1 [Cricetulus griseus]"]
[null,"BGI_novel_G001277",2331,4.5614640353243,11.8398670760404,-1.37608403681445,"DOWN",0.0380655097009571,"NA","GO:0005634//nucleus;GO:0097169//AIM2 inflammasome complex","GO:0042802//identical protein binding;GO:0003690//double-stranded DNA binding","GO:0070269//pyroptosis;GO:0035690//cellular response to drug;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0002218//activation of innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0032461//positive regulation of protein oligomerization;GO:0035458//cellular response to interferon-beta;GO:0002230//positive regulation of defense response to virus by host;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033209//tumor necrosis factor-mediated signaling pathway","K12966//absent in melanoma 2","gi|293341479|ref|XP_001057147.2|//PREDICTED: interferon-inducible protein AIM2 [Rattus norvegicus]"]
[null,"BGI_novel_G001314",4660,1179.48283109062,2546.4644513635,-1.11034115893318,"DOWN",0.00525526360807476,"NA","GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004745//retinol dehydrogenase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity","GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0055114//oxidation-reduction process","K13369//17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]","gi|27545384|ref|NP_775427.1|//17-beta-hydroxysteroid dehydrogenase type 6 [Rattus norvegicus]"]
[null,"BGI_novel_G001358",2299,27.905967167819,9.43966774988022,1.56376566159482,"UP",0.0261261631103947,"NA","NA","NA","NA","K00142//acyl-CoA synthetase [EC:6.2.1.-]","gi|149035189|gb|EDL89893.1|//similar to 2-aminoadipic 6-semialdehyde dehydrogenase (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G001428",2343,141.593545417627,61.0319960722374,1.214117821124,"UP",0.0454397540447961,"NA","NA","NA","NA","K13209//RNA-binding protein EWS","gi|564345594|ref|XP_006236078.1|//PREDICTED: RNA-binding protein EWS isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G001456",7710,32.4351438346892,93.69721902286,-1.5304483921505,"DOWN",0.0282092904022612,"NA","NA","NA","NA","K09254//c-Rel proto-oncogene protein","gi|564317469|ref|XP_006221931.1|//PREDICTED: proto-oncogene c-Rel isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G001457",8666,72.8841361128779,31.4663968786011,1.21179284370973,"UP",0.0330799856774007,"NA","NA","NA","NA","K09254//c-Rel proto-oncogene protein","gi|625220020|ref|XP_007650034.1|//PREDICTED: proto-oncogene c-Rel isoform X3 [Cricetulus griseus]"]
[null,"BGI_novel_G001526",2685,2.72930002763336,44.5546623255952,-4.02897350570154,"DOWN",{"v":2.48945518550413e-09,"d":"2.49E-09"},"NA","GO:0016605//PML body;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis","NA","gi|148704240|gb|EDL36187.1|//zinc finger, MYM-type 2, isoform CRA_b, partial [Mus musculus]"]
[null,"BGI_novel_G001564",2642,23.8847902852086,50.6140802686838,-1.08344657269194,"DOWN",0.0296263320322913,"NA","NA","GO:0005507//copper ion binding","NA","K05810//laccase domain-containing protein","gi|27663906|ref|XP_233749.1|//PREDICTED: laccase domain-containing protein 1 [Rattus norvegicus]"]
[null,"BGI_novel_G001583",6006,212.876542040827,443.654218248205,-1.05941870507361,"DOWN",0.00253748231364198,"NA","GO:0070062//extracellular exosome;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane","GO:0044822//poly(A) RNA binding;GO:0005515//protein binding","GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0051260//protein homooligomerization","K03129//transcription initiation factor TFIID subunit 4;K03849//alpha-1,3-glucosyltransferase [EC:2.4.1.265];K00849//galactokinase [EC:2.7.1.6]","gi|149050122|gb|EDM02446.1|//rCG36961 [Rattus norvegicus]"]
[null,"BGI_novel_G001584",3332,5.07671186460942,2.06443070273812,1.29815038833452,"UP",0.0495722135893053,"NA","NA","NA","NA","K10693//E3 ubiquitin-protein ligase MYCBP2 [EC:2.3.2.27]","gi|672079010|ref|XP_008769160.1|//PREDICTED: probable E3 ubiquitin-protein ligase MYCBP2 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G001600",5729,19.8198138105725,69.4817614732181,-1.80969091936871,"DOWN",0.00833992981612857,"NA","NA","GO:0044822//poly(A) RNA binding","NA","NA","gi|293342292|ref|XP_002725195.1|//PREDICTED: protein FAM208A isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G001610",7780,29.6342581056506,80.2526286243106,-1.43728270752306,"DOWN",0.0190742059053139,"NA","NA","NA","NA","K11757//protein polybromo-1","gi|672029123|ref|XP_008769451.1|//PREDICTED: protein polybromo-1 isoform X14 [Rattus norvegicus]"]
[null,"BGI_novel_G001624",1864,31.7541517929635,63.8502990756189,-1.00774814378622,"DOWN",0.0374885836575958,"NA","GO:0012505//endomembrane system;GO:0019898//extrinsic component of membrane","GO:0005543//phospholipid binding","NA","K18953//factor associated with neutral sphingomyelinase activation","gi|564388246|ref|XP_006252824.1|//PREDICTED: WD repeat- and FYVE domain-containing protein 4 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G001638",5674,29.7628310359753,66.8440981178763,-1.167288423813,"DOWN",0.00859905675448694,"NA","GO:0015630//microtubule cytoskeleton","GO:0008017//microtubule binding","GO:0001578//microtubule bundle formation","NA","gi|672029180|ref|XP_008769842.1|//PREDICTED: serine-rich coiled-coil domain-containing protein 2 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G001642",2090,198.772557244145,97.513341193051,1.02744707220005,"UP",0.0324321369161145,"NA","NA","NA","NA","K11644//paired amphipathic helix protein Sin3a","gi|50510595|dbj|BAD32283.1|//mKIAA0700 protein [Mus musculus]"]
[null,"BGI_novel_G001649",4822,450.637695473163,220.084182879839,1.03391253425031,"UP",0.0435977790063095,"NA","GO:0005615//extracellular space","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0010951//negative regulation of endopeptidase activity","K03910//alpha-2-macroglobulin","gi|112893|sp|P14046.1|A1I3_RAT//RecName: Full=Alpha-1-inhibitor 3; AltName: Full=Alpha-1-inhibitor 3 variant II; Short=Alpha-1-inhibitor III; Flags: Precursor"]
[null,"BGI_novel_G001654",2854,11.1421986838002,2.22810051690109,2.32214772302101,"UP",0.000998193140988917,"NA","NA","NA","NA","K13705//abhydrolase domain-containing protein 12B","gi|524972772|ref|XP_005086235.1|//PREDICTED: leucine-rich repeat-containing protein 25 [Mesocricetus auratus]"]
[null,"BGI_novel_G001656",2728,25.4216560158385,80.2013183194059,-1.6575679380098,"DOWN",0.013580252253977,"NA","NA","NA","NA","K13705//abhydrolase domain-containing protein 12B","gi|524972772|ref|XP_005086235.1|//PREDICTED: leucine-rich repeat-containing protein 25 [Mesocricetus auratus]"]
[null,"BGI_novel_G001681",5709,34.6342769867494,10.0961693212288,1.77839254610017,"UP",0.00970264604201687,"NA","NA","NA","NA","K13705//abhydrolase domain-containing protein 12B","gi|148708998|gb|EDL40944.1|//mCG148429 [Mus musculus]"]
[null,"BGI_novel_G001685",2093,25.4716366451302,8.44732165077843,1.59232576993866,"UP",0.0188632566474001,"NA","NA","NA","NA","K14844//pumilio homology domain family member 6","gi|68163507|ref|NP_001020207.1|//pumilio homolog 3 [Rattus norvegicus]"]
[null,"BGI_novel_G001703",1265,22.7879153599337,4.6093266930599,2.30564102317524,"UP",0.00105722797852511,"NA","GO:0016021//integral component of membrane","GO:0015299//solute:proton antiporter activity","GO:1902600//hydrogen ion transmembrane transport","NA","gi|431913190|gb|ELK14872.1|//Transmembrane and coiled-coil domain-containing protein 3 [Pteropus alecto]"]
[null,"BGI_novel_G001706",5520,328.255771852075,801.240213133026,-1.28741445100412,"DOWN",0.0021892138988656,"NA","GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005587//collagen type IV trimer","GO:0005201//extracellular matrix structural constituent","GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0006351//transcription, DNA-templated","K06237//collagen, type IV, alpha","gi|149057578|gb|EDM08821.1|//procollagen, type IV, alpha 2 (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G001715",10987,62.462094565409,19.2263349614112,1.69989717485898,"UP",0.0147769578497037,"NA","NA","NA","NA","K05098//kinase insert domain protein receptor [EC:2.7.10.1]","gi|642103658|emb|CDQ75102.1|//unnamed protein product [Oncorhynchus mykiss]"]
[null,"BGI_novel_G001767",5734,47.3827727807381,11.5722264946097,2.0336961603051,"UP",0.00351384688125994,"NA","GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0046964//3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity","GO:0098779//mitophagy in response to mitochondrial depolarization;GO:0098792//xenophagy;GO:1902559//3'-phospho-5'-adenylyl sulfate transmembrane transport;GO:0002230//positive regulation of defense response to virus by host","K15277//solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3","gi|564319743|ref|XP_006222434.1|//PREDICTED: adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G001819",1966,154.978353474864,76.951077120926,1.01005329595419,"UP",0.0103616927951762,"NA","GO:0016020//membrane;GO:0030686//90S preribosome;GO:0032040//small-subunit processome;GO:0005739//mitochondrion;GO:0034455//t-UTP complex","GO:0030515//snoRNA binding;GO:0044822//poly(A) RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0045943//positive regulation of transcription from RNA polymerase I promoter","K14550//U3 small nucleolar RNA-associated protein 10","gi|157822545|ref|NP_001101888.1|//HEAT repeat-containing protein 1 [Rattus norvegicus] "]
[null,"BGI_novel_G001831",7213,35.7401677724536,103.266224970813,-1.530750160801,"DOWN",0.0146798991166921,"NA","NA","NA","NA","K19930//SRC kinase signaling inhibitor 1","gi|672082596|ref|XP_008770128.1|//PREDICTED: sickle tail protein homolog isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G001833",7631,20.2931023341413,6.4477092428151,1.65413084319755,"UP",0.0153518027230155,"NA","GO:0005737//cytoplasm","NA","GO:0048706//embryonic skeletal system development","K19930//SRC kinase signaling inhibitor 1","gi|672030318|ref|XP_008772254.1|//PREDICTED: sickle tail protein homolog isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G001840",6116,167.60537482892,430.976218651844,-1.36253984869109,"DOWN",0.000721481234355154,"NA","GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0071944//cell periphery","GO:0043237//laminin-1 binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0043394//proteoglycan binding","GO:0007160//cell-matrix adhesion;GO:0032836//glomerular basement membrane development;GO:0010811//positive regulation of cell-substrate adhesion","K06826//nidogen (entactin)","gi|109505096|ref|XP_213954.4|//PREDICTED: nidogen-1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G001897",2585,155.752014028815,354.372193473239,-1.18601458551158,"DOWN",0.037481557800791,"NA","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0090187//positive regulation of pancreatic juice secretion;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0060046//regulation of acrosome reaction;GO:0090281//negative regulation of calcium ion import;GO:0071375//cellular response to peptide hormone stimulus;GO:0045471//response to ethanol;GO:2001256//regulation of store-operated calcium entry;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0031667//response to nutrient levels;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0090277//positive regulation of peptide hormone secretion;GO:0050679//positive regulation of epithelial cell proliferation","NA","gi|124846|sp|P09656.2|ISK1L_RAT//RecName: Full=Serine protease inhibitor Kazal-type 1-like; AltName: Full=Calcium transport inhibitor; AltName: Full=Caltrin; AltName: Full=Pancreatic secretory trypsin inhibitor II; Short=PSTI-II; Flags: Precursor"]
[null,"BGI_novel_G001898",2585,155.752014028815,354.372193473239,-1.18601458551158,"DOWN",0.037481557800791,"NA","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0090187//positive regulation of pancreatic juice secretion;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0060046//regulation of acrosome reaction;GO:0090281//negative regulation of calcium ion import;GO:0071375//cellular response to peptide hormone stimulus;GO:0045471//response to ethanol;GO:2001256//regulation of store-operated calcium entry;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0031667//response to nutrient levels;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0090277//positive regulation of peptide hormone secretion;GO:0050679//positive regulation of epithelial cell proliferation","NA","gi|124846|sp|P09656.2|ISK1L_RAT//RecName: Full=Serine protease inhibitor Kazal-type 1-like; AltName: Full=Calcium transport inhibitor; AltName: Full=Caltrin; AltName: Full=Pancreatic secretory trypsin inhibitor II; Short=PSTI-II; Flags: Precursor"]
[null,"BGI_novel_G001899",10547,35.7431763308728,12.7154764030554,1.4910823300941,"UP",0.0241157643476749,"NA","NA","NA","NA","NA","gi|690969208|ref|NP_001164005.2|//colorectal mutant cancer protein [Rattus norvegicus]"]
[null,"BGI_novel_G001908",6916,46.4027488427679,145.898904325505,-1.65268687240874,"DOWN",0.00645820145035977,"NA","GO:0030424//axon;GO:0005887//integral component of plasma membrane","GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity;GO:0004888//transmembrane signaling receptor activity","GO:0051642//centrosome localization;GO:0001755//neural crest cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:2001224//positive regulation of neuron migration;GO:0006915//apoptotic process","K06842//semaphorin 6","gi|564320606|ref|XP_006222634.1|//PREDICTED: semaphorin-6A isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G001909",5337,51.8806106612838,108.311855044207,-1.06192379265259,"DOWN",0.0158255614397748,"NA","NA","NA","NA","NA","gi|149064227|gb|EDM14430.1|//rCG46981, isoform CRA_b [Rattus norvegicus]"]
[null,"BGI_novel_G001966",9857,23.7931271093803,7.56433122214227,1.65326045474149,"UP",0.0153342338136247,"NA","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","gi|564394258|ref|XP_006255073.1|//PREDICTED: zinc finger protein 236 isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G001969",5027,28.885781383888,8.60108763412723,1.7477685115686,"UP",0.0109027218876245,"NA","NA","NA","NA","K09236//teashirt","gi|672030980|ref|XP_008772400.1|//PREDICTED: teashirt homolog 1 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G001971",4732,19.6695408227284,173.317391240092,-3.13938124254729,"DOWN",{"v":3.35986461203517e-06,"d":"3.36E-06"},"NA","NA","NA","NA","K09236//teashirt","gi|672083937|ref|XP_008770460.1|//PREDICTED: LOW QUALITY PROTEIN: teashirt homolog 1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G001983",1581,11.9920574101986,4.68024985715933,1.35742173922888,"UP",0.0404048097551221,"NA","GO:0005615//extracellular space","GO:0102209//trans-permethrin hydrolase activity","GO:0006486//protein glycosylation","K03927//carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]","gi|149032323|gb|EDL87214.1|//rCG39026 [Rattus norvegicus]"]
[null,"BGI_novel_G002007",3277,56.9636893143424,13.349455703727,2.0932616667953,"UP",0.00271601919599269,"NA","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K10591//E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]","gi|109507829|ref|XP_341655.3|//PREDICTED: HEAT repeat-containing protein 3 [Rattus norvegicus]"]
[null,"BGI_novel_G002042",6539,18.0682641517375,50.8351526053963,-1.49236855772897,"DOWN",0.0131840897951635,"NA","GO:0016021//integral component of membrane","NA","NA","K13092//nuclear protein NHN1;K12821//pre-mRNA-processing factor 40;K11423//histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43]","gi|167539430|ref|XP_001751113.1|//hypothetical protein [Monosiga brevicollis MX1]"]
[null,"BGI_novel_G002046",3595,7.23677810884187,19.6578304505497,-1.44168466440479,"DOWN",0.0308170432715848,"NA","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0070266//necroptotic process;GO:0006468//protein phosphorylation;GO:0070207//protein homotrimerization","K08849//mixed lineage kinase domain-like [EC:2.7.11.1]","gi|149038205|gb|EDL92565.1|//rCG51567 [Rattus norvegicus]"]
[null,"BGI_novel_G002114",3717,23.766671754785,71.5198881909924,-1.58940459630892,"DOWN",0.0141932088846964,"NA","NA","NA","NA","K17253//lactadherin","gi|149058979|gb|EDM09986.1|//rCG44653, isoform CRA_b [Rattus norvegicus]"]
[null,"BGI_novel_G002115",1006,6.03989027255344,15.320577008963,-1.34287638829571,"DOWN",0.0489152986116656,"NA","NA","NA","NA","NA","gi|149039003|gb|EDL93223.1|//adenylate kinase 1, isoform CRA_b [Rattus norvegicus]"]
[null,"BGI_novel_G002129",4690,36.3809930057536,76.8637320239384,-1.07911810502943,"DOWN",0.0103725567217918,"NA","NA","GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0001886//endothelial cell morphogenesis;GO:0097178//ruffle assembly;GO:0035023//regulation of Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity","K13744//Rho guanine nucleotide exchange factor 26","gi|109464919|ref|XP_227201.4|//PREDICTED: rho guanine nucleotide exchange factor 26 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002137",2303,12.4658041552198,32.9411115709982,-1.40191328596495,"DOWN",0.0146816738049491,"NA","GO:0070062//extracellular exosome;GO:0072557//IPAF inflammasome complex","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070269//pyroptosis;GO:0042742//defense response to bacterium;GO:0006954//inflammatory response;GO:0016045//detection of bacterium;GO:0071391//cellular response to estrogen stimulus;GO:0009966//regulation of signal transduction;GO:0045087//innate immune response","K12807//baculoviral IAP repeat-containing protein 1","gi|109464318|ref|XP_226743.4|//PREDICTED: baculoviral IAP repeat-containing protein 1e-like [Rattus norvegicus]"]
[null,"BGI_novel_G002172",3397,79.7502750709483,252.896446550768,-1.66498536575283,"DOWN",{"v":8.05763532530667e-05,"d":"8.06E-05"},"NA","NA","NA","NA","K03996//complement component 7","gi|672015464|ref|XP_008773300.1|//PREDICTED: complement component C7 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002173",1215,11.1110143155235,30.3961477268329,-1.45189796926893,"DOWN",0.0237960020310759,"NA","NA","NA","NA","K03996//complement component 7","gi|672041790|ref|XP_008759053.1|//PREDICTED: complement component C7 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G002234",6284,369.267892996185,159.755486216321,1.20880235284896,"UP",0.00839103423438226,"NA","GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0070064//proline-rich region binding","GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis","K20045//intersectin;K20705//dynamin-binding protein","gi|564300507|ref|XP_006224226.1|//PREDICTED: SH3 domain-containing protein 19 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G002270",5616,143.342903771675,70.5352963319068,1.02305320782847,"UP",0.0352688153967794,"NA","NA","NA","NA","K06102//cingulin","gi|149030735|gb|EDL85772.1|//rCG51904, isoform CRA_b, partial [Rattus norvegicus]"]
[null,"BGI_novel_G002308",1111,7.2005478041301,2.45148231755858,1.55445231269375,"UP",0.0224087766290763,"NA","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0004556//alpha-amylase activity","NA","K01176//alpha-amylase [EC:3.2.1.1]","gi|148680466|gb|EDL12413.1|//mCG11265, isoform CRA_a, partial [Mus musculus]"]
[null,"BGI_novel_G002319",3654,75.9944704969578,16.6862186407495,2.18723739474276,"UP",0.000921810965507927,"NA","NA","NA","NA","K10203//elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]","gi|1000765535|ref|XP_015605877.1|//PREDICTED: elongation of very long chain fatty acids protein 6 [Cephus cinctus]"]
[null,"BGI_novel_G002371",723,16.6192177062041,5.98566273486573,1.47326957681675,"UP",0.0350252465497449,"NA","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:1990111//spermatoproteasome complex;GO:0005737//cytoplasm;GO:0005839//proteasome core complex","GO:0004298//threonine-type endopeptidase activity","GO:0052548//regulation of endopeptidase activity;GO:0019882//antigen processing and presentation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045444//fat cell differentiation","K02740//20S proteasome subunit beta 8 [EC:3.4.25.1]","gi|672085898|ref|XP_008771008.1|//PREDICTED: proteasome subunit beta type-8-like [Rattus norvegicus]"]
[null,"BGI_novel_G002373",1072,197.252416669842,445.92678984773,-1.17676389897641,"DOWN",0.00235141891389996,"NA","GO:0010008//endosome membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0009986//cell surface;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane;GO:0005771//multivesicular body","GO:0023026//MHC class II protein complex binding","GO:0016064//immunoglobulin mediated immune response;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0002922//positive regulation of humoral immune response;GO:0002636//positive regulation of germinal center formation;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0045059//positive thymic T cell selection;GO:0048839//inner ear development;GO:0045582//positive regulation of T cell differentiation;GO:0015031//protein transport","K06752//major histocompatibility complex, class II","gi|971524|emb|CAA62306.1|//MAr [Mus musculus]"]
[null,"BGI_novel_G002414",708,3214.42525504219,1592.79669811147,1.01299866872213,"UP",0.0253252243427128,"NA","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0009986//cell surface;GO:0043209//myelin sheath;GO:0005737//cytoplasm","GO:0005125//cytokine activity;GO:0050178//phenylpyruvate tautomerase activity;GO:0004167//dopachrome isomerase activity;GO:0042056//chemoattractant activity;GO:0005126//cytokine receptor binding;GO:0032403//protein complex binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002675//positive regulation of acute inflammatory response;GO:0007420//brain development;GO:0032570//response to progesterone;GO:0032572//response to menaquinone;GO:0030890//positive regulation of B cell proliferation;GO:0045821//positive regulation of glycolytic process;GO:0046326//positive regulation of glucose import;GO:0032355//response to estradiol;GO:0042756//drinking behavior;GO:0033197//response to vitamin E;GO:0071157//negative regulation of cell cycle arrest;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0061081//positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0001516//prostaglandin biosynthetic process;GO:0045087//innate immune response;GO:0070301//cellular response to hydrogen peroxide;GO:0042493//response to drug;GO:0002035//brain renin-angiotensin system;GO:0009612//response to mechanical stimulus;GO:0010739//positive regulation of protein kinase A signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0009408//response to heat;GO:0043268//positive regulation of potassium ion transport;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071456//cellular response to hypoxia;GO:0061078//positive regulation of prostaglandin secretion involved in immune response;GO:0010629//negative regulation of gene expression;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0007283//spermatogenesis;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0051384//response to glucocorticoid;GO:0014911//positive regulation of smooth muscle cell migration;GO:0070207//protein homotrimerization;GO:0043406//positive regulation of MAP kinase activity;GO:0032868//response to insulin;GO:0042060//wound healing;GO:0048680//positive regulation of axon regeneration;GO:0032269//negative regulation of cellular protein metabolic process;GO:0090344//negative regulation of cell aging;GO:0002821//positive regulation of adaptive immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050715//positive regulation of cytokine secretion;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0090238//positive regulation of arachidonic acid secretion;GO:0001942//hair follicle development","K07253//phenylpyruvate tautomerase [EC:5.3.2.1]","gi|13591985|ref|NP_112313.1|//macrophage migration inhibitory factor [Rattus norvegicus]"]
[null,"BGI_novel_G002430",3373,26.752374479148,2.31756559312521,3.5289848709284,"UP",{"v":2.70344142223245e-07,"d":"2.70E-07"},"NA","NA","NA","NA","K12898//heterogeneous nuclear ribonucleoprotein F/H","gi|664771894|ref|XP_008505148.1|//PREDICTED: heterogeneous nuclear ribonucleoprotein H3 isoform X1 [Equus przewalskii]"]
[null,"BGI_novel_G002478",3988,115.76483983655,55.3367701811569,1.06488679737032,"UP",0.027364935029333,"NA","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment","GO:0004129//cytochrome-c oxidase activity","GO:0033617//mitochondrial respiratory chain complex IV assembly;GO:0006754//ATP biosynthetic process;GO:0006119//oxidative phosphorylation;GO:1902600//hydrogen ion transmembrane transport;GO:0007030//Golgi organization;GO:0010638//positive regulation of organelle organization","K14998//surfeit locus 1 family protein","gi|33086478|gb|AAP92551.1|//Ab1-205 [Rattus norvegicus]"]
[null,"BGI_novel_G002480",3659,38.6151313041039,196.00931920028,-2.34368406630937,"DOWN",{"v":2.00732320456701e-05,"d":"2.01E-05"},"NA","GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0050436//microfibril binding","GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060481//lobar bronchus epithelium development","K08626//a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-]","gi|62644808|ref|XP_231125.3|//PREDICTED: ADAMTS-like protein 2 [Rattus norvegicus]"]
[null,"BGI_novel_G002505",4949,4.86199436568374,224.014657233684,-5.52590109888819,"DOWN",{"v":9.04613382568278e-18,"d":"9.05E-18"},"NA","GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0001726//ruffle;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion;GO:0045202//synapse","GO:0051015//actin filament binding;GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0070097//delta-catenin binding;GO:0005080//protein kinase C binding;GO:0008022//protein C-terminus binding;GO:0051019//mitogen-activated protein kinase binding;GO:0019905//syntaxin binding;GO:0017124//SH3 domain binding;GO:0070064//proline-rich region binding;GO:0030145//manganese ion binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:0002333//transitional one stage B cell differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0006914//autophagy;GO:0060020//Bergmann glial cell differentiation;GO:0030041//actin filament polymerization;GO:0006909//phagocytosis;GO:0006975//DNA damage induced protein phosphorylation;GO:0045930//negative regulation of mitotic cell cycle;GO:0034446//substrate adhesion-dependent cell spreading;GO:0048146//positive regulation of fibroblast proliferation;GO:1904528//positive regulation of microtubule binding;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0090135//actin filament branching;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:1900275//negative regulation of phospholipase C activity;GO:0071871//response to epinephrine;GO:0002322//B cell proliferation involved in immune response;GO:0033690//positive regulation of osteoblast proliferation;GO:0021587//cerebellum morphogenesis;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0001922//B-1 B cell homeostasis;GO:0031113//regulation of microtubule polymerization;GO:0048536//spleen development;GO:0051353//positive regulation of oxidoreductase activity;GO:1903210//glomerular visceral epithelial cell apoptotic process;GO:0050853//B cell receptor signaling pathway;GO:0046632//alpha-beta T cell differentiation;GO:0043525//positive regulation of neuron apoptotic process;GO:0050798//activated T cell proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:1990051//activation of protein kinase C activity;GO:1904531//positive regulation of actin filament binding;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:1902715//positive regulation of interferon-gamma secretion;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:2001020//regulation of response to DNA damage stimulus;GO:0032956//regulation of actin cytoskeleton organization;GO:0022408//negative regulation of cell-cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:1900006//positive regulation of dendrite development;GO:0042493//response to drug;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:1900042//positive regulation of interleukin-2 secretion;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0042770//signal transduction in response to DNA damage;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:2000773//negative regulation of cellular senescence;GO:0030514//negative regulation of BMP signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0048668//collateral sprouting;GO:1903055//positive regulation of extracellular matrix organization;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006281//DNA repair;GO:0048538//thymus development;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030516//regulation of axon extension;GO:0030035//microspike assembly;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008306//associative learning;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K06619//abelson tyrosine-protein kinase 1 [EC:2.7.10.2]","gi|392346207|ref|XP_003749487.1|//PREDICTED: tyrosine-protein kinase ABL1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002523",6430,209.928130672825,94.1388112908028,1.15703396174184,"UP",0.0221630011481375,"NA","GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032794//GTPase activating protein binding","GO:0007165//signal transduction;GO:0051223//regulation of protein transport;GO:0043547//positive regulation of GTPase activity","K20131//Rab5 GDP/GTP exchange factor","gi|672016642|ref|XP_008773555.1|//PREDICTED: GTPase-activating protein and VPS9 domain-containing protein 1 isoform X7 [Rattus norvegicus]"]
[null,"BGI_novel_G002553",4842,34.634625759264,92.0395398712042,-1.41003868615408,"DOWN",0.00841670542413158,"NA","NA","NA","NA","K04512//dishevelled associated activator of morphogenesis","gi|564301657|ref|XP_006224499.1|//PREDICTED: formin-like protein 2 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002558",4895,2.31904236683733,13.0300304284718,-2.49023937088391,"DOWN",0.000418830330310348,"NA","GO:0072686//mitotic spindle;GO:0000922//spindle pole;GO:0051233//spindle midzone;GO:0044291//cell-cell contact zone;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0030496//midbody;GO:0009898//cytoplasmic side of plasma membrane;GO:0030057//desmosome","NA","GO:0032467//positive regulation of cytokinesis;GO:0007043//cell-cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0043547//positive regulation of GTPase activity","K05690//catenin (cadherin-associated protein), delta 1","gi|392339263|ref|XP_003753774.1|//PREDICTED: plakophilin-4 isoform X8 [Rattus norvegicus]"]
[null,"BGI_novel_G002598",1952,7.31026314083563,19.314307986482,-1.40167474449243,"DOWN",0.045190835156154,"NA","NA","NA","NA","K06487//integrin alpha V","gi|149022401|gb|EDL79295.1|//integrin alpha V (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G002722",3278,65.9464671029156,22.993485189472,1.52007021708847,"UP",0.000558840331828267,"NA","NA","NA","NA","K10591//E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]","gi|149043073|gb|EDL96647.1|//rCG32392, isoform CRA_a [Rattus norvegicus]"]
[null,"BGI_novel_G002732",6925,33.2666970334124,2.49179549897299,3.73882105505785,"UP",{"v":4.02970992155077e-08,"d":"4.03E-08"},"NA","GO:0035097//histone methyltransferase complex","GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005515//protein binding","GO:2000327//positive regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0040029//regulation of gene expression, epigenetic;GO:0048854//brain morphogenesis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0051569//regulation of histone H3-K4 methylation;GO:0021895//cerebral cortex neuron differentiation;GO:0001701//in utero embryonic development;GO:0048812//neuron projection morphogenesis;GO:0080182//histone H3-K4 trimethylation;GO:0002052//positive regulation of neuroblast proliferation","K09228//KRAB domain-containing zinc finger protein","gi|672017732|ref|XP_008773839.1|//PREDICTED: zinc finger protein 335 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G002733",5592,2.31343624313132,28.8526324044829,-3.64059370610329,"DOWN",{"v":1.04294894603001e-07,"d":"1.04E-07"},"NA","GO:0035097//histone methyltransferase complex","GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005515//protein binding","GO:2000327//positive regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0040029//regulation of gene expression, epigenetic;GO:0048854//brain morphogenesis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0051569//regulation of histone H3-K4 methylation;GO:0021895//cerebral cortex neuron differentiation;GO:0001701//in utero embryonic development;GO:0048812//neuron projection morphogenesis;GO:0080182//histone H3-K4 trimethylation;GO:0002052//positive regulation of neuroblast proliferation","K09228//KRAB domain-containing zinc finger protein","gi|672017732|ref|XP_008773839.1|//PREDICTED: zinc finger protein 335 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G002734",3115,13.166563879359,35.1758312860522,-1.41770562814028,"DOWN",0.0431597950897957,"NA","NA","NA","NA","K18985//engulfment and cell motility protein 2","gi|149042886|gb|EDL96460.1|//engulfment and cell motility 2, ced-12 homolog (C. elegans), isoform CRA_c [Rattus norvegicus]"]
[null,"BGI_novel_G002736",3987,39.9530848660682,18.0756678516944,1.14425794891713,"UP",0.0412113420177058,"NA","GO:0016021//integral component of membrane","NA","GO:0090290//positive regulation of osteoclast proliferation;GO:0072674//multinuclear osteoclast differentiation;GO:0071391//cellular response to estrogen stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0034241//positive regulation of macrophage fusion;GO:0045672//positive regulation of osteoclast differentiation","K04282//thyrotropin-releasing hormone receptor","gi|149042881|gb|EDL96455.1|//rCG32320 [Rattus norvegicus]"]
[null,"BGI_novel_G002785",2471,1.59301816132929,4.22650399092619,-1.40770209768293,"DOWN",0.0361527922332303,"NA","NA","NA","NA","K09188//histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]","gi|564303127|ref|XP_006224850.1|//PREDICTED: histone-lysine N-methyltransferase 2C isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002794",2206,31.9411077488804,11.6616231655408,1.45364573840857,"UP",0.0254067215502752,"NA","NA","NA","NA","K09188//histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]","gi|149031399|gb|EDL86389.1|//rCG56742 [Rattus norvegicus]"]
[null,"BGI_novel_G002822",5194,121.004414819349,585.833992550239,-2.27543222200523,"DOWN",{"v":2.23217355723131e-08,"d":"2.23E-08"},"NA","GO:0070062//extracellular exosome;GO:0005584//collagen type I trimer;GO:0005615//extracellular space","GO:0048407//platelet-derived growth factor binding;GO:0005201//extracellular matrix structural constituent;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0030674//protein binding, bridging;GO:0046332//SMAD binding","GO:0008217//regulation of blood pressure;GO:0043589//skin morphogenesis;GO:0071873//response to norepinephrine;GO:0030199//collagen fibril organization;GO:0001568//blood vessel development;GO:0071230//cellular response to amino acid stimulus;GO:0071300//cellular response to retinoic acid;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0070208//protein heterotrimerization;GO:0097067//cellular response to thyroid hormone stimulus;GO:0001501//skeletal system development","K06236//collagen, type I, alpha","gi|672048983|ref|XP_008760958.1|//PREDICTED: collagen alpha-2(I) chain isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G002845",4447,7.27166503624959,24.6938997246476,-1.7637970390935,"DOWN",0.0102863488834704,"NA","GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0042147//retrograde transport, endosome to Golgi;GO:0043547//positive regulation of GTPase activity","K20161//DENN domain-containing protein 2","gi|564303575|ref|XP_006224941.1|//PREDICTED: DENN domain-containing protein 2A isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G002869",4469,154.888167600675,70.8508212362774,1.1283704555574,"UP",0.0137159914025706,"NA","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","gi|62647202|ref|XP_342682.2|//PREDICTED: protein KRBA1 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G002893",4531,7.62512374413159,25.6844467074246,-1.75206233997658,"DOWN",0.00812854124403861,"NA","NA","GO:0005509//calcium ion binding","GO:0007596//blood coagulation","K11498//centromeric protein E;K18744//caprin-2","gi|149037054|gb|EDL91615.1|//rCG55340 [Rattus norvegicus]"]
[null,"BGI_novel_G002949",5700,19.0666502626949,63.1947651115683,-1.72875364922051,"DOWN",0.00560767429098484,"NA","GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005737//cytoplasm","NA","GO:0090162//establishment of epithelial cell polarity","K06791//immunoglobulin superfamily, member 11;K19944//TBC1 domain family member 10","gi|564304113|ref|XP_001077268.4|//PREDICTED: FERM domain-containing protein 4B isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G002951",1573,64.6810579237085,28.6487738847057,1.17486988014612,"UP",0.0115288204844229,"NA","GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit","GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome","GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0097421//liver regeneration;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing;GO:0071549//cellular response to dexamethasone stimulus","K02912//large subunit ribosomal protein L32e","gi|556719835|ref|XP_005955798.1|//PREDICTED: 60S ribosomal protein L32 isoform X1 [Pantholops hodgsonii]"]
[null,"BGI_novel_G002966",2725,35.9438290304334,12.1706127993078,1.56234229406413,"UP",0.0216343509231957,"NA","NA","NA","NA","NA","gi|45478072|gb|AAS66207.1|//LRRG00116 [Rattus norvegicus]"]
[null,"BGI_novel_G002968",5372,33.5609696216437,598.684327559464,-4.15693920076955,"DOWN",{"v":2.12055606121947e-19,"d":"2.12E-19"},"NA","NA","NA","NA","K03910//alpha-2-macroglobulin","gi|148277039|ref|NP_783327.2|//alpha-2-macroglobulin-P precursor [Mus musculus]"]
[null,"BGI_novel_G002977",410,60.1914138332398,20.489581249829,1.55466720456395,"UP",0.0246511679663378,"NA","NA","NA","NA","K03910//alpha-2-macroglobulin","gi|204933|gb|AAA63494.1|//alpha-1-inhibitor 3, partial [Rattus norvegicus]"]
[null,"BGI_novel_G002987",6588,9.28384771329697,26.2312996381128,-1.49849452528016,"DOWN",0.0256182360030373,"NA","NA","NA","NA","K11643//chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]","gi|564349052|ref|XP_006237463.1|//PREDICTED: chromodomain-helicase-DNA-binding protein 4 isoform X9 [Rattus norvegicus]"]
[null,"BGI_novel_G002996",5950,14.656073141226,5.41401394935982,1.4367280985294,"UP",0.0316050485398149,"NA","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0000779//condensed chromosome, centromeric region;GO:0005737//cytoplasm;GO:0000799//nuclear condensin complex;GO:0045120//pronucleus","GO:0042393//histone binding;GO:0003682//chromatin binding","GO:0051304//chromosome separation;GO:0051301//cell division;GO:0010032//meiotic chromosome condensation;GO:0007076//mitotic chromosome condensation","K06677//condensin complex subunit 1","gi|672051120|ref|XP_575668.5|//PREDICTED: LOW QUALITY PROTEIN: condensin complex subunit 1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003002",5637,43.9377556813124,94.4122264737332,-1.10351252257607,"DOWN",0.00892008618655486,"NA","NA","NA","NA","K09448//transcriptional enhancer factor","gi|589950612|ref|XP_006987957.1|//PREDICTED: transcriptional enhancer factor TEF-3 [Peromyscus maniculatus bairdii]"]
[null,"BGI_novel_G003007",2010,97.7202246411996,425.766267165259,-2.1233325664954,"DOWN",{"v":1.58880050198517e-06,"d":"1.59E-06"},"NA","NA","NA","NA","K03910//alpha-2-macroglobulin","gi|293347095|ref|XP_001066684.2|//PREDICTED: ovostatin homolog 2 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003008",3088,24.3437316469594,55.7510016548286,-1.19544739005252,"DOWN",0.0408546030460366,"NA","NA","NA","NA","K03910//alpha-2-macroglobulin","gi|672051271|ref|XP_008761561.1|//PREDICTED: LOW QUALITY PROTEIN: ovostatin homolog 2 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G003011",2982,67.7709538411494,197.119578118591,-1.54033209155351,"DOWN",0.0267947078893597,"NA","NA","NA","NA","K03910//alpha-2-macroglobulin","gi|293347095|ref|XP_001066684.2|//PREDICTED: ovostatin homolog 2 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003015",1601,6.98941717710044,18.4113593976292,-1.39735208714299,"DOWN",0.0472690031547204,"NA","GO:0016021//integral component of membrane","NA","NA","K17517//C-type lectin domain family 12 member B;K10074//C-type lectin domain family 7 member A;K10069//C-type lectin domain family 1 member A","gi|564304518|ref|XP_006225150.1|//PREDICTED: killer cell lectin-like receptor 5 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003023",2291,25.4326049419967,58.6112114654522,-1.20449741939747,"DOWN",0.0164200157376752,"NA","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol","GO:0030331//estrogen receptor binding;GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0030308//negative regulation of cell growth;GO:0007264//small GTPase mediated signal transduction;GO:0009725//response to hormone;GO:0008285//negative regulation of cell proliferation","K07855//Ras-related and estrogen-regulated growth inhibitor","gi|392340179|ref|XP_001072746.3|//PREDICTED: ras-related and estrogen-regulated growth inhibitor [Rattus norvegicus]"]
[null,"BGI_novel_G003024",3033,22.1201811809462,57.7417990175378,-1.38425285485168,"DOWN",0.00502030189441376,"NA","NA","NA","NA","K17277//epidermal growth factor receptor kinase substrate 8","gi|476007242|sp|F1M3L7.2|EPS8_RAT//RecName: Full=Epidermal growth factor receptor kinase substrate 8"]
[null,"BGI_novel_G003060",551,284.09412073414,137.785832692316,1.04394141957629,"UP",0.0169438545719925,"NA","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0022627//cytosolic small ribosomal subunit","GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome","GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing","K02969//small subunit ribosomal protein S20e","gi|675706185|ref|XP_009007421.1|//PREDICTED: 40S ribosomal protein S20, partial [Callithrix jacchus]"]
[null,"BGI_novel_G003065",2685,30.722916567748,76.4516650155726,-1.31523274236841,"DOWN",0.00782430227627117,"NA","GO:0032541//cortical endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0033198//response to ATP;GO:0031585//regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0090316//positive regulation of intracellular protein transport;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0035108//limb morphogenesis;GO:0032237//activation of store-operated calcium channel activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:1901879//regulation of protein depolymerization;GO:0007389//pattern specification process;GO:0071277//cellular response to calcium ion;GO:0031647//regulation of protein stability;GO:0042264//peptidyl-aspartic acid hydroxylation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0060021//palate development;GO:0060325//face morphogenesis;GO:0008285//negative regulation of cell proliferation","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","gi|564304963|ref|XP_006225258.1|//PREDICTED: aspartyl/asparaginyl beta-hydroxylase isoform X12 [Rattus norvegicus]"]
[null,"BGI_novel_G003101",6887,79.9090547451544,233.763304687538,-1.54861758480789,"DOWN",0.0229194802244482,"NA","GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0001784//phosphotyrosine binding;GO:0017080//sodium channel regulator activity;GO:0008092//cytoskeletal protein binding;GO:0051117//ATPase binding;GO:0004725//protein tyrosine phosphatase activity","GO:0045930//negative regulation of mitotic cell cycle;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0006470//protein dephosphorylation;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0098902//regulation of membrane depolarization during action potential","K18027//tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]","gi|568927055|ref|XP_006538160.1|//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X2 [Mus musculus]"]
[null,"BGI_novel_G003103",1049,3.00198226809759,8.82675438892429,-1.55596759883638,"DOWN",0.0270623092344035,"NA","GO:0016020//membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0003682//chromatin binding;GO:0005509//calcium ion binding","GO:0007155//cell adhesion","K17495//CUB and sushi domain-containing protein","gi|564351170|ref|XP_006238256.1|//PREDICTED: sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003131",5330,14.9194039833345,5.69688531794407,1.38894463317363,"UP",0.0365591633326472,"NA","GO:0032593//insulin-responsive compartment;GO:0030904//retromer complex;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0032869//cellular response to insulin stimulus;GO:0072659//protein localization to plasma membrane;GO:0015031//protein transport","K20163//DENN domain-containing protein 4","gi|672053077|ref|XP_008762068.1|//PREDICTED: DENN domain-containing protein 4C isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003171",3896,13.0069263315526,4.96945607006178,1.38812022297863,"UP",0.0367801554343501,"NA","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding","GO:0045893//positive regulation of transcription, DNA-templated","NA","gi|77917610|ref|NP_001030085.1|//vasculin-like protein 1 [Rattus norvegicus]"]
[null,"BGI_novel_G003174",1924,103.963583425933,28.8761767246739,1.84812662303427,"UP",0.00707570168143091,"NA","GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding","GO:0051865//protein autoubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway","NA","gi|880954492|ref|XP_012978848.1|//PREDICTED: E3 ubiquitin-protein ligase RNF220 [Mesocricetus auratus]"]
[null,"BGI_novel_G003181",1778,1653.81342363443,788.386653540989,1.06882122625329,"UP",0.000685295351902634,"NA","NA","NA","NA","K01816//hydroxypyruvate isomerase [EC:5.3.1.22]","gi|392348250|ref|XP_002729578.2|//PREDICTED: putative hydroxypyruvate isomerase isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003188",1956,221.303674398518,1154.0217283143,-2.38257107766645,"DOWN",{"v":5.33187736914732e-10,"d":"5.33E-10"},"NA","NA","NA","NA","K09276//Y-box-binding protein 1","gi|181486|gb|AAA35750.1|//DNA-binding protein B, partial [Homo sapiens]"]
[null,"BGI_novel_G003190",1936,41.5342502631213,16.1839239735423,1.35974006475479,"UP",0.0192770873342895,"NA","GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071001//U4/U6 snRNP","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0043021//ribonucleoprotein complex binding","GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization;GO:0045070//positive regulation of viral genome replication","K09567//peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]","gi|148698503|gb|EDL30450.1|//mCG4207, isoform CRA_b, partial [Mus musculus]"]
[null,"BGI_novel_G003225",2425,100.894981166025,42.3600094728645,1.25207959496698,"UP",0.0451236880566871,"NA","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0051117//ATPase binding","GO:0002028//regulation of sodium ion transport","NA","gi|165377302|ref|NP_080274.2|//sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor [Mus musculus]"]
[null,"BGI_novel_G003231",8347,518.808049997119,107.856254846017,2.26609102078451,"UP",{"v":4.16130753622508e-06,"d":"4.16E-06"},"NA","NA","NA","NA","K06107//erythrocyte membrane protein band 4.1","gi|564306208|ref|XP_006225616.1|//PREDICTED: protein 4.1 isoform X10 [Rattus norvegicus]"]
[null,"BGI_novel_G003255",7317,252.397528419762,613.170219018472,-1.28058984571032,"DOWN",0.000139448965140329,"NA","NA","NA","NA","K06255//heparan sulfate proteoglycan 2 (perlecan)","gi|568930638|ref|XP_006538638.1|//PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein isoform X2 [Mus musculus]"]
[null,"BGI_novel_G003274",6739,231.234830650956,89.9752462554644,1.3617586749757,"UP",0.00457117212272425,"NA","GO:0005829//cytosol;GO:0045202//synapse","GO:0050661//NADP binding;GO:0072341//modified amino acid binding;GO:0004489//methylenetetrahydrofolate reductase (NAD(P)H) activity;GO:0050660//flavin adenine dinucleotide binding;GO:0032403//protein complex binding","GO:0042493//response to drug;GO:0043200//response to amino acid;GO:0070829//heterochromatin maintenance;GO:0046500//S-adenosylmethionine metabolic process;GO:0033274//response to vitamin B2;GO:0055114//oxidation-reduction process;GO:0001666//response to hypoxia;GO:0031060//regulation of histone methylation;GO:0050667//homocysteine metabolic process;GO:0070555//response to interleukin-1;GO:0035999//tetrahydrofolate interconversion;GO:0051593//response to folic acid;GO:0009086//methionine biosynthetic process","K00297//methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]","gi|564306446|ref|XP_006225676.1|//PREDICTED: methylenetetrahydrofolate reductase isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G003295",2086,28.8465067709542,75.3403641785558,-1.38502638374303,"DOWN",0.00905419714476432,"NA","GO:0016021//integral component of membrane","NA","NA","K02893//large subunit ribosomal protein L23Ae;K15544//RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16];K11094//U2 small nuclear ribonucleoprotein B''","gi|380876869|sp|D4A2Q0.1|CA233_RAT//RecName: Full=Fibronectin type-III domain-containing transmembrane protein C1orf233 homolog; Flags: Precursor"]
[null,"BGI_novel_G003308",5559,34.3623699180209,12.6856532158093,1.43763173102351,"UP",0.0415822382115809,"NA","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding","GO:0035914//skeletal muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated","K09407//forkhead box protein N","gi|392348630|ref|XP_237502.5|//PREDICTED: forkhead box protein N2 [Rattus norvegicus]"]
[null,"BGI_novel_G003309",5064,15.8724422600449,86.0200478054643,-2.43814880328591,"DOWN",{"v":8.32453879702165e-05,"d":"8.32E-05"},"NA","GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment","NA","GO:0035845//photoreceptor cell outer segment organization;GO:0050908//detection of light stimulus involved in visual perception;GO:1903546//protein localization to photoreceptor outer segment","K13172//serine/arginine repetitive matrix protein 2;K04622//G protein-coupled receptor family C group 6 member A","gi|564306826|ref|XP_006225764.1|//PREDICTED: uncharacterized protein C2orf71 homolog isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003336",8177,13.4755510775927,4.95473283403817,1.44346510012068,"UP",0.0310215615518599,"NA","NA","NA","NA","K20473//neuroblastoma-amplified sequence","gi|755541484|ref|XP_006515278.2|//PREDICTED: neuroblastoma-amplified sequence isoform X1 [Mus musculus]"]
[null,"BGI_novel_G003347",6559,95.5378495245251,193.649536244335,-1.01930373792343,"DOWN",0.0107991269474132,"NA","NA","NA","NA","K05636//laminin, beta 1","gi|148704971|gb|EDL36918.1|//laminin B1 subunit 1, partial [Mus musculus]"]
[null,"BGI_novel_G003353",2257,33.1122173776502,12.55181042497,1.39946815684709,"UP",0.045360190450363,"NA","NA","NA","NA","K11318//ataxin-7","gi|564307077|ref|XP_006225813.1|//PREDICTED: ataxin-7-like protein 1 isoform X4 [Rattus norvegicus]"]
[null,"BGI_novel_G003355",1688,3.12285780597748,10.1665791537311,-1.70289553812768,"DOWN",0.0154806086707934,"NA","NA","NA","NA","K11318//ataxin-7","gi|564307081|ref|XP_006225815.1|//PREDICTED: ataxin-7-like protein 1 isoform X7 [Rattus norvegicus]"]
[null,"BGI_novel_G003363",6619,56.7355417911384,13.42933728167,2.07886467825728,"UP",0.00289025936430029,"NA","GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane","GO:0004622//lysophospholipase activity;GO:0047499//calcium-independent phospholipase A2 activity","GO:0050482//arachidonic acid secretion;GO:0019369//arachidonic acid metabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0008219//cell death;GO:0001516//prostaglandin biosynthetic process;GO:0043651//linoleic acid metabolic process","K16815//calcium-independent phospholipase A2-gamma","gi|392340992|ref|XP_003754218.1|//PREDICTED: calcium-independent phospholipase A2-gamma [Rattus norvegicus]"]
[null,"BGI_novel_G003370",5949,39.4224410814678,13.5854685141486,1.53695279262907,"UP",0.0291136173570078,"NA","NA","NA","NA","NA","gi|564307175|ref|XP_006225829.1|//PREDICTED: HEAT repeat-containing protein 5A isoform X5 [Rattus norvegicus]"]
[null,"BGI_novel_G003393",3245,13.3519698717446,41.63886704707,-1.64087821042179,"DOWN",0.0195310009975114,"NA","GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome;GO:0000243//commitment complex","GO:0030627//pre-mRNA 5'-splice site binding","GO:0000395//mRNA 5'-splice site recognition","K13217//pre-mRNA-processing factor 39","gi|148704703|gb|EDL36650.1|//PRP39 pre-mRNA processing factor 39 homolog (yeast), isoform CRA_a, partial [Mus musculus]"]
[null,"BGI_novel_G003412",3093,37.967284987653,14.8308643440252,1.35615415596332,"UP",0.0440560654528875,"NA","NA","NA","NA","K04608//metabotropic glutamate receptor 6/7/8;K06467//CD22 antigen","gi|642054418|emb|CDQ91736.1|//unnamed protein product [Oncorhynchus mykiss]"]
[null,"BGI_novel_G003473",1913,288.731759203822,127.885541337314,1.17487664311004,"UP",0.00545687811417038,"NA","GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0005525//GTP binding;GO:0004019//adenylosuccinate synthase activity","GO:0044208//'de novo' AMP biosynthetic process","K01939//adenylosuccinate synthase [EC:6.3.4.4]","gi|149044044|gb|EDL97426.1|//rCG27771, isoform CRA_b [Rattus norvegicus]"]
[null,"BGI_novel_G003490",1119,12.2699243712283,40.0267043208521,-1.705836476806,"DOWN",0.0156363988543205,"NA","NA","NA","NA","K06856//immunoglobulin heavy chain","gi|1220486|gb|AAA91896.1|//gamma-2a immunoglobulin heavy chain [Rattus norvegicus]"]
[null,"BGI_novel_G003493",1126,15.271826148299,49.0388701075562,-1.68305315406391,"DOWN",0.0170705916091602,"NA","NA","NA","NA","K06856//immunoglobulin heavy chain","gi|56788960|gb|AAH88423.1|//LOC367586 protein [Rattus norvegicus]"]
[null,"BGI_novel_G003502",5541,28.0723458604154,59.2531858651446,-1.07774309802514,"DOWN",0.0241310482310175,"NA","NA","NA","NA","K17598//synaptotagmin-like protein","gi|149034329|gb|EDL89079.1|//rCG21039, isoform CRA_a [Rattus norvegicus]"]
[null,"BGI_novel_G003503",4013,82.1636392090214,24.9122055884281,1.72164732777485,"UP",0.0146112008596525,"NA","NA","NA","NA","K17598//synaptotagmin-like protein","gi|149034329|gb|EDL89079.1|//rCG21039, isoform CRA_a [Rattus norvegicus]"]
[null,"BGI_novel_G003527",1506,15.373655608965,61.7088667234354,-2.0050175443064,"DOWN",0.00051778916837432,"NA","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction","GO:0003779//actin binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0005516//calmodulin binding","GO:0031032//actomyosin structure organization;GO:0071260//cellular response to mechanical stimulus;GO:0042127//regulation of cell proliferation;GO:0042060//wound healing;GO:0030336//negative regulation of cell migration;GO:0010628//positive regulation of gene expression;GO:0032970//regulation of actin filament-based process;GO:0050765//negative regulation of phagocytosis;GO:0030097//hemopoiesis","K07441//beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141];K06712//butyrophilin;K20526//transgelin","gi|564358403|ref|XP_006241100.1|//PREDICTED: calponin-2 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003548",11583,1000.53201201789,122.521410012176,3.02966154679077,"UP",{"v":1.27625602306255e-13,"d":"1.28E-13"},"NA","NA","NA","NA","K04608//metabotropic glutamate receptor 6/7/8","gi|148708998|gb|EDL40944.1|//mCG148429 [Mus musculus]"]
[null,"BGI_novel_G003569",11700,403.491521849789,838.227488011865,-1.05480347261135,"DOWN",0.00354149746006313,"NA","GO:0016021//integral component of membrane;GO:0043235//receptor complex","GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity","GO:0001525//angiogenesis;GO:0035335//peptidyl-tyrosine dephosphorylation","K05694//receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]","gi|392341425|ref|XP_003754334.1|//PREDICTED: receptor-type tyrosine-protein phosphatase beta isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003572",538,104.896826458876,236.001322882126,-1.16982391511217,"DOWN",0.0218238254259571,"NA","NA","NA","NA","K13915//lysozyme C [EC:3.2.1.17]","gi|149066890|gb|EDM16623.1|//rCG48637 [Rattus norvegicus]"]
[null,"BGI_novel_G003609",8395,26.0387048309004,7.69824888097242,1.75805547171332,"UP",0.0105264166159679,"NA","NA","NA","NA","K10593//E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]","gi|564308597|ref|XP_006226121.1|//PREDICTED: E3 ubiquitin-protein ligase UBR5 isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003614",5412,38.7979658418371,104.62598102873,-1.43118823059319,"DOWN",0.0185869258727585,"NA","GO:0097433//dense body;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0005739//mitochondrion;GO:0031982//vesicle","GO:0017075//syntaxin-1 binding;GO:0019894//kinesin binding;GO:0008017//microtubule binding","GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus","K17975//kinectin","gi|564308632|ref|XP_006226125.1|//PREDICTED: syntabulin isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003662",2028,86.0873500963695,41.8586981641167,1.04027381633014,"UP",0.0128558231310347,"NA","NA","NA","NA","K21245//transcription factor SPT20 homolog;K17963//peroxisome proliferator-activated receptor gamma coactivator-related protein 1","gi|197245725|gb|AAI68705.1|//Cyhr1 protein [Rattus norvegicus]"]
[null,"BGI_novel_G003677",4155,337.988368582028,155.3492026708,1.12145876208824,"UP",0.00177036529220028,"NA","GO:0034993//LINC complex;GO:0000784//nuclear chromosome, telomeric region;GO:0000794//condensed nuclear chromosome;GO:0005639//integral component of nuclear inner membrane","GO:0042802//identical protein binding;GO:0005521//lamin binding","GO:0051642//centrosome localization;GO:0030335//positive regulation of cell migration;GO:0031022//nuclear migration along microfilament;GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0090292//nuclear matrix anchoring at nuclear membrane;GO:0006998//nuclear envelope organization","K19347//SUN domain-containing protein 1/2","gi|564309029|ref|XP_006226221.1|//PREDICTED: SUN domain-containing protein 2 isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G003694",3203,32.8464018202134,11.2649748396162,1.54389124695634,"UP",0.0264987138410133,"NA","GO:0005874//microtubule;GO:0005930//axoneme;GO:0005737//cytoplasm","GO:0070738//tubulin-glycine ligase activity;GO:0005524//ATP binding;GO:0070740//tubulin-glutamic acid ligase activity;GO:0070736//protein-glycine ligase activity, initiating;GO:0018169//ribosomal S6-glutamic acid ligase activity;GO:0008766//UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity;GO:0070737//protein-glycine ligase activity, elongating;GO:0043773//coenzyme F420-0 gamma-glutamyl ligase activity;GO:0043774//coenzyme F420-2 alpha-glutamyl ligase activity","GO:0018094//protein polyglycylation","K16608//tubulin monoglycylase TTLL3/8 [EC:6.3.2.-]","gi|149017522|gb|EDL76526.1|//rCG59308, isoform CRA_c [Rattus norvegicus]"]
[null,"BGI_novel_G003709",1317,116.742385817459,46.877719104336,1.31635417701644,"UP",0.0444539376875667,"NA","GO:0044545//NSL complex","GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific)","GO:0043984//histone H4-K16 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043981//histone H4-K5 acetylation","K18401//KAT8 regulatory NSL complex subunit 2","gi|50926997|gb|AAH79169.1|//RGD1303127 protein [Rattus norvegicus]"]
[null,"BGI_novel_G003727",2078,295.798537723582,629.489038423636,-1.0895663353545,"DOWN",0.0112644590182624,"NA","GO:0070062//extracellular exosome;GO:0045095//keratin filament","GO:0005198//structural molecule activity;GO:0019899//enzyme binding","NA","K07605//type II keratin, basic","gi|392349739|ref|XP_003750458.1|//PREDICTED: LOW QUALITY PROTEIN: keratin, type II cytoskeletal 79 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003754",3921,22.3695771881081,46.3834520699813,-1.0520722079999,"DOWN",0.0368289771812639,"NA","NA","NA","NA","K06061//mastermind","gi|149020689|gb|EDL78494.1|//rCG31664 [Rattus norvegicus]"]
[null,"BGI_novel_G003755",7553,98.6221482805798,212.380642581022,-1.10666869335752,"DOWN",0.00593561476830084,"NA","NA","NA","NA","K06104//angiomotin like","gi|568960196|ref|XP_006510730.1|//PREDICTED: angiomotin-like protein 1 isoform X2 [Mus musculus]"]
[null,"BGI_novel_G003791",2289,128.673652073389,51.7306222734668,1.31462621850762,"UP",0.0250308818456782,"NA","NA","NA","NA","K15682//ligand of Numb protein X 3/4 [EC:2.3.2.27]","gi|149029902|gb|EDL85014.1|//PDZ domain containing 4 (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G003796",1680,687.058092144349,189.895381187559,1.85522727162884,"UP",0.0041392438897724,"NA","NA","NA","NA","K03283//heat shock 70kDa protein 1/8","gi|77415383|gb|AAI06170.1|//Hspa8 protein, partial [Mus musculus]"]
[null,"BGI_novel_G003797",1550,447.966121453955,113.498839328871,1.98071208484183,"UP",0.00329360108355848,"NA","NA","NA","NA","K03283//heat shock 70kDa protein 1/8","gi|734548180|gb|KHN76385.1|//Heat shock 70 kDa protein 1A/1B [Toxocara canis]"]
[null,"BGI_novel_G003822",1786,74.8059197702447,184.470278246619,-1.30216404126159,"DOWN",0.0326082903781786,"NA","NA","NA","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","gi|148693894|gb|EDL25841.1|//ubiquitin-conjugating enzyme E2Q (putative) 2, isoform CRA_a, partial [Mus musculus]"]
[null,"BGI_novel_G003829",1394,80.9751353337278,39.1248190855746,1.04939489320614,"UP",0.0414072856137906,"NA","NA","NA","NA","K01598//phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]","gi|672062132|ref|XP_008764525.1|//PREDICTED: phosphopantothenoylcysteine decarboxylase isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G003882",6125,36.0691593112842,123.894951830538,-1.78027970251166,"DOWN",{"v":3.35680729493093e-06,"d":"3.36E-06"},"NA","NA","NA","NA","K08132//collagen, type XII, alpha","gi|672023106|ref|XP_008756047.1|//PREDICTED: collagen alpha-1(XII) chain isoform X1 [Rattus norvegicus]"]
[null,"BGI_novel_G003901",3655,78.1495467619374,36.6412625100664,1.09276829241761,"UP",0.0461790879459098,"NA","NA","NA","NA","K13160//heterogeneous nuclear ribonucleoprotein Q","gi|148691168|gb|EDL23115.1|//mCG145372, partial [Mus musculus]"]
[null,"BGI_novel_G003942",10287,5.06342891975481,13.9549275935454,-1.46258803457355,"DOWN",0.0290740938536871,"NA","NA","NA","NA","K05727//dedicator of cytokinesis protein 3","gi|803234542|ref|XP_011977385.1|//PREDICTED: dedicator of cytokinesis protein 3 isoform X7 [Ovis aries musimon]"]
[null,"BGI_novel_G003950",9267,9.42118341522654,35.3392620764951,-1.90729171873239,"DOWN",0.00590403707409239,"NA","GO:0002116//semaphorin receptor complex;GO:0005887//integral component of plasma membrane","GO:0017154//semaphorin receptor activity;GO:0032794//GTPase activating protein binding","GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:0048675//axon extension;GO:0007162//negative regulation of cell adhesion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043931//ossification involved in bone maturation;GO:0043547//positive regulation of GTPase activity;GO:0050772//positive regulation of axonogenesis;GO:0008360//regulation of cell shape;GO:0033689//negative regulation of osteoblast proliferation;GO:0030334//regulation of cell migration;GO:0051493//regulation of cytoskeleton organization;GO:1900220//semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis","K06821//plexin B","gi|564310645|ref|XP_006226632.1|//PREDICTED: plexin-B1 [Rattus norvegicus]"]
[null,"BGI_novel_G003966",5245,51.6751358991363,24.6931799784088,1.06535763959482,"UP",0.0363130697722321,"NA","NA","NA","NA","K04575//amyotrophic lateral sclerosis 2 protein","gi|149018406|gb|EDL77047.1|//similar to RN49018 (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G003998",2825,23.8824289419906,7.38322419076155,1.69362670056318,"UP",0.0133082682870314,"NA","GO:0070062//extracellular exosome;GO:0005764//lysosome","GO:0008146//sulfotransferase activity","GO:0051923//sulfation","K01025","gi|672064044|ref|XP_008765007.1|//PREDICTED: sulfotransferase 1C2-like isoform X3 [Rattus norvegicus]"]
[null,"BGI_novel_G004036",3671,5.53229787852197,15.3617373039398,-1.47339064039483,"DOWN",0.0280362171574558,"NA","NA","GO:0008270//zinc ion binding","NA","K04511//prickle","gi|672023724|ref|XP_008756184.1|//PREDICTED: prickle-like protein 4 [Rattus norvegicus]"]
[null,"BGI_novel_G004039",2696,525.843440056957,246.383487836645,1.09372775574133,"UP",0.0363485711669608,"NA","NA","GO:0008270//zinc ion binding","NA","K04511//prickle","gi|672023724|ref|XP_008756184.1|//PREDICTED: prickle-like protein 4 [Rattus norvegicus]"]
[null,"BGI_novel_G004070",3968,23.754520228671,7.17576078841557,1.72699836644875,"UP",0.0118128222673447,"NA","NA","NA","NA","K01847//methylmalonyl-CoA mutase [EC:5.4.99.2]","gi|149069236|gb|EDM18677.1|//rCG43751 [Rattus norvegicus]"]
[null,"BGI_novel_G004101",5680,43.0904094829592,91.8694812170859,-1.09221887360143,"DOWN",0.0260472699505223,"NA","GO:0016021//integral component of membrane","NA","NA","K04574//neurofilament heavy polypeptide;K21125//mucin-5AC","gi|149046360|gb|EDL99253.1|//similar to RW1 protein (predicted) [Rattus norvegicus]"]
[null,"BGI_novel_G004167",2017,42.9188836017593,17.4820317643799,1.29573968464114,"UP",0.01291222054726,"NA","NA","NA","NA","NA","gi|298351843|sp|D3Z750.2|MRO2A_MOUSE//RecName: Full=Maestro heat-like repeat-containing protein family member 2A; AltName: Full=HEAT repeat-containing protein 7B1"]
[null,"BGI_novel_G004169",5217,47.0194340882893,106.811858206446,-1.18374274293222,"DOWN",0.0261436825617006,"NA","NA","NA","NA","K06238//collagen, type VI, alpha","gi|564312009|ref|XP_006227004.1|//PREDICTED: collagen alpha-3(VI) chain isoform X7 [Rattus norvegicus]"]
[null,"BGI_novel_G004179",3929,26.3804131374108,122.853590682187,-2.21940096085258,"DOWN",{"v":5.55028598120645e-07,"d":"5.55E-07"},"NA","GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007155//cell adhesion","K19479//collagen, type X, alpha","gi|672066409|ref|XP_008765663.1|//PREDICTED: EMILIN-2 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G004183",711,110.693348413838,264.48916479212,-1.25664008843411,"DOWN",0.0232127787611167,"NA","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0031838//haptoglobin-hemoglobin complex;GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0005506//iron ion binding;GO:0004601//peroxidase activity;GO:0031722//hemoglobin beta binding;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding;GO:0031721//hemoglobin alpha binding","GO:0010999//regulation of eIF2 alpha phosphorylation by heme;GO:0015671//oxygen transport;GO:0051291//protein heterooligomerization;GO:0070293//renal absorption;GO:0042542//response to hydrogen peroxide;GO:0048821//erythrocyte development;GO:0006749//glutathione metabolic process;GO:0042744//hydrogen peroxide catabolic process;GO:0070527//platelet aggregation;GO:0010942//positive regulation of cell death","K13823//hemoglobin subunit beta","gi|164448680|ref|NP_001106694.1|//hemoglobin subunit beta-2 [Rattus norvegicus]"]
[null,"BGI_novel_G004184",1185,19.9735186690316,47.4564224801864,-1.2485148365289,"DOWN",0.0316117265806267,"NA","GO:0072562//blood microparticle;GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding","GO:0015671//oxygen transport","K13823//hemoglobin subunit beta","gi|40445397|ref|NP_942071.1|//hemoglobin, beta adult major chain [Rattus norvegicus]"]
[null,"BGI_novel_G004251",2309,54.0426467459503,2.68583513090951,4.33065567933525,"UP",{"v":6.50779685035813e-11,"d":"6.51E-11"},"NA","NA","NA","NA","K10592//E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]","gi|755566680|ref|XP_011246157.1|//PREDICTED: E3 ubiquitin-protein ligase HUWE1 isoform X4 [Mus musculus]"]
[null,"BGI_novel_G004274",757,15.380812776176,56.4161833731906,-1.87497732667598,"DOWN",0.00722530516371445,"NA","GO:0005634//nucleus;GO:0005576//extracellular region","GO:0005549//odorant binding;GO:0005215//transporter activity","GO:0006810//transport","NA","gi|149042373|gb|EDL96080.1|//probasin, isoform CRA_b [Rattus norvegicus]"]
[null,"BGI_novel_G004304",3959,22.402228860425,58.3828381055618,-1.38190206762262,"DOWN",0.0175636195575549,"NA","NA","NA","NA","K11661//helicase SRCAP [EC:3.6.4.-]","gi|564323063|ref|XP_006227503.1|//PREDICTED: armadillo repeat-containing X-linked protein 4 isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G004319",2588,177.667005043203,707.114623341383,-1.99276831502404,"DOWN",0.000222476556910279,"NA","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0015349//thyroid hormone transmembrane transporter activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0042562//hormone binding","GO:0042493//response to drug;GO:0010951//negative regulation of endopeptidase activity;GO:0043434//response to peptide hormone;GO:0034695//response to prostaglandin E;GO:0007568//aging;GO:0070327//thyroid hormone transport;GO:0009791//post-embryonic development;GO:0033189//response to vitamin A;GO:0051412//response to corticosterone","K20734//thyroxine-binding globulin","gi|564323179|ref|XP_001054915.3|//PREDICTED: thyroxine-binding globulin isoform X2 [Rattus norvegicus]"]
[null,"BGI_novel_G004347",2947,27.6156176495232,70.31102127842,-1.34826645498646,"DOWN",0.0276782497887114,"NA","GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0004842//ubiquitin-protein transferase activity","GO:0016567//protein ubiquitination","K10447//kelch-like protein 9/13","gi|149059979|gb|EDM10795.1|//kelch-like 13 (Drosophila) [Rattus norvegicus]"]
[null,"BGI_novel_G004379",282,3.11821636987483,9.50055662622885,-1.60729100303726,"DOWN",0.0222253374089248,"NA","GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity","GO:0070936//protein K48-linked ubiquitination","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","gi|743063465|gb|AJB84606.1|//UBE2Q2Y [Rattus norvegicus]"]